• Tuberculosis and Respiratory Diseases
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• 제65권1호
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• pp.52-56
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• 2008

저자들은 갑상샘 암의 림프절 전이를 동반한 30세 사르코이드증 환자를 경험하였기에 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제55권3호
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• pp.303-310
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• 2003

종격종 림프관종은 림프관에서 기원하는 드문 양성 종양이다. 대부분 출생 시 존재하며 생후 첫 2년 이내 발견되는데, 성인에서는 매우 드물게 발생하며, 대부분 증상이 없이 단순 흉부 방사선촬영에서 이상소견이 발견되어 진단된다. 저자들은 단순 흉부 방사선촬영에서 이상소견이 발견된 3명의 환자에서 수술을 통하여 조직학적으로 종격동 림프관종임을 진단하고 치료한 3명의 환자를 경험하여 이를 보고하는 바이다.

• Advances in pediatric surgery
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• 제9권2호
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• pp.94-97
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• 2003

The teratoma is a unique complex neoplasm and is one of the most frequent pediatric tumors originated from the extragonadal germ cells. Mature teratoma is composed of mature differentiated tissues, while immature teratoma always contains embryonic tissues of variable degrees of immaturity, especially in the neuroepithelial elements. Diagnosis of teratoma is relatively easy by conventional radiologic study, but the immaturity can be identified only by histopathological examination. Between January 1993 to December 2002, 63 cases of teratoma were operated and analysed retrospectively at the Chonnam University Hospital Female to male ratio was about 3:1 and age distribution was relatively even. Among 63 cases, gonadal teratoma was the most common (52.4%), followed by sacrococcygeal (25.4%), retroperitoneal (9.5%) and mediastinal teratoma (9.5%). Fifty-six cases were mature teratomas and seven were immature teratomas. Alpha-fetoprotein (AFP) was elevated in 4 of 6 immature cases, but in 2 of 51 mature ones Elevated AFP progressively returned to normal range by 1 month after operation in all. Complete excision of the mass was performed, and major complication was not noticed. In five immature cases, PEB chemotherapy (Cisplatin, Etoposide, Bleomycin) was performed. Two of 2 cases in histological grade II were well tolerated to the aggressive chemotherapy. One of three cases in grade III expired due to severe bone marrow depression, and two of them expired by tumor recurrences. In conclusion, immature teratoma in histological grade III showed high potentiality of recurrence. Therefore, postoperative chemotherapy has to be applied to the high graded immature tumors.

• Tuberculosis and Respiratory Diseases
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• 제44권2호
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• pp.425-429
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• 1997

저자들은 68세 여자에서 전종격동에 발생한 흉선 유암종 1예를 광학 및 전자현미경소견들로 확진하였기에 문헌고찰과 함께 보고하는 바이다.

• Journal of Yeungnam Medical Science
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• 제35권1호
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• pp.114-120
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• 2018

Tracheal tumors are rare and difficult to diagnose. Moreover, delays in diagnosis are very common because the symptoms are nonspecific. As a result, tracheal tumors are commonly mistreated as chronic obstructive pulmonary disease or bronchial asthma. We report a case of a 49-year-old male who presented with a 3-month history of dyspnea and cough. Chest computed tomography scan showed a $1.5{\times}1.3cm$ homogenous tumor originating from the right lateral wall of the tracheobronchial angle into the tracheal lumen as well as a $0.5{\times}0.4cm$ round nodular lesion at the right upper lobe with multiple mediastinal lymph nodes enlargement. Bronchoscopic findings revealed a broad-based, polypoid lesion nearly obstructing the airway of the right main bronchus. The patient was diagnosed with pleomorphic adenoma which is the most common benign tumor of the salivary glands, but rarely appears in the trachea. Upon surgery, tracheal pleomorphic adenoma and co-existing active pulmonary tuberculoma that had been mistreated as bronchial asthma over 3 months was revealed. Following surgery, the patient underwent anti-tuberculosis treatment. No recurrence has been detected in the 3 years since treatment and the patient is now asymptomatic.

• Journal of Chest Surgery
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• 제29권9호
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• pp.1036-1039
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• 1996

폐의 암육종은 상피조직과 간염조직이 혼재하는 악성종양으로 전체 폐종양의 0.3%에 불과한 매우 희귀한 종양이며 흡연과 깊은 관계가 있는 질환이다. 폐에서의 위치에 따라 비교적 예후가 양호한 endobronchial type과 빠른 원격전이로 예후가 불량한 solid parenchymal type으로 분류된다. 비침습적 진단방법으론 발견이 어렵고 생검에 의해 종종 발견된다. 폐문과 종격동으로 전이를 잘하며 광범위 절제가 치료의 기본이고 항암제 요법을 병용하기도 한다. 암육종의 예후는 매우 불랑하여 술후 평균생존 기간은 9개월 정도이고 2년까지 생존율은 10% 미만인것으로 보고 된다.

• 대한세포병리학회지
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• 제5권2호
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• pp.189-193
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• 1994

Malignant thymoma is usually manifested as a mediastinal mass. Occasiomally, these tumors may be associated with a variety of systemic syndromes, such as myasthenia gravis, pure red cell aplasia or hypogammaglobulinemia However, it is generally accepted that thymomas rarely metastasize and the frequency of extrathoracic metastasis has been reported as 1 to 15%. In general, nuclear changes of tumor cells such as enlarged size, irregular shape and altered textures are determining factors in the assessment of the grade of malignancy. We experienced a case of malignant thymoma of anterior mediastinum in a 35-year-old woman. After 3 years, she developed recurrent malignant thymoma in the right supraclavicular area, diagnosed by aspiration biopsy cytology.

• Journal of Chest Surgery
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• 제21권4호
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• pp.766-771
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• 1988

Von Recklinghausen`s neurofibromatosis, tuberous sclerosis and encephalotrigeminal angiomatosis[Sturge-Kalischer-Weber syndrome] are frequently classified under the heading of organic neurocutaneous syndromes. Both neurofibromatosis and tuberous sclerosis are believed to represent instances of simple autosomal dominant heredity. Multiple neurofibroma and cafe*-au-lait spots are the hallmarks of the van-Recklinghausen`s disease. The characteristic features of the fully developed syndrome are [1] pigmentation of the skin, including cafe*-au-lait spots, pigmented freckles and males, and occasionally a generalized darkening of the skin; [2] subcutaneous nodules and deep neurofibromatous tumors and diffuse plexiform growths of neural tissue; [3] skeletal anomalies, especially scoliosis; and [4] predilection to malignancy. In recent years cystic lung disease, usually of the so-called honeycomb lung variety, has been reported on several occasions in patients with tuberous sclerosis. This association has been shown to our sporadically as well as in members of a single family. Little attention has been paid to the presence of cystic lung disease in association with neurofibromatosis. Currently, most think of thoracic involvement in neurofibromatosis in terms of posterior mediastinal neuroma, pheochromocytoma, meningocele or, less commonly, parenchymal pulmonary neurofibromatosis. Author have experienced a case of von Recklinghausen`s disease. This case developed a huge neurofibroma in the both side thorax and invaded to the Lt. 7th rib.

• Journal of Chest Surgery
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• 제54권6호
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• pp.528-531
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• 2021

Pulmonary sclerosing pneumocytoma (PSP) is a tumor of pneumocytic origin that is classified as a benign neoplasm. To date, aggressive behavior of this tumor has rarely been reported. Here, we describe a case of a 56-year-old woman with a huge, 19-cm PSP that resulted in mediastinal shift and showed microscopic endobronchial invasion and necrosis. The differential diagnosis included malignant mesenchymal tumors, such as solitary fibrous tumor; however, PSP was confirmed based on the characteristic thyroid transcription factor 1 positivity and membranous expression of Ki-67 on immunohistochemical staining of tumor cells.

• 대한영상의학회지
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• 제84권1호
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• pp.270-274
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• 2023

갈비뼈에서 발생하는 골연골종은 드물다. 골연골종은 갈비뼈에서 자라서 흉부 밖으로는 피하로 확장되거나 흉부 안으로는 폐 또는 종격동 구조물들을 압박한다. 23세 남자 환자가 작년부터 만져지는 유방 덩이를 주소로 내원했다. 임상 검사에서 소엽 모양의 단단한 뼈 돌기로 촉진되었다. 흉부 영상과 조영증강 CT에서 오른쪽 4번째 갈비뼈의 갈비뼈연골접합부의 앞쪽에 뼈의 과성장이 보였고 대흉근을 밀고 있었다. 유방의 단단한 덩이를 주소로 온 경우 다른 흉곽종양과 함께 골연골종이 감별진단에 포함되어야 한다.