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http://dx.doi.org/10.5090/jcs.21.016

Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review  

Lee, Hyun Soo (Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine)
Kim, Jina (Department of Radiology and the Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine)
Moon, Duk Hwan (Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine)
Park, Chul Hwan (Department of Radiology and the Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine)
Jeon, Tae Joo (Department of Nuclear medicine, Gangnam Severance Hospital, Yonsei University College of Medicine)
Lee, Sungsoo (Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine)
Cha, Yoon Jin (Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Publication Information
Journal of Chest Surgery / v.54, no.6, 2021 , pp. 528-531 More about this Journal
Abstract
Pulmonary sclerosing pneumocytoma (PSP) is a tumor of pneumocytic origin that is classified as a benign neoplasm. To date, aggressive behavior of this tumor has rarely been reported. Here, we describe a case of a 56-year-old woman with a huge, 19-cm PSP that resulted in mediastinal shift and showed microscopic endobronchial invasion and necrosis. The differential diagnosis included malignant mesenchymal tumors, such as solitary fibrous tumor; however, PSP was confirmed based on the characteristic thyroid transcription factor 1 positivity and membranous expression of Ki-67 on immunohistochemical staining of tumor cells.
Keywords
Pulmonary sclerosing hemangioma; Computed tomography; Immunohistochemistry; Case report;
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