• Journal of Ecology and Environment
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• 제33권3호
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• pp.217-222
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• 2010

To determine whether or not the female Korean salamander, Hynobius leechii, responds to water currents and, if so, whether those responses depend on their reproductive conditions, we evaluated the responses of ovulated and oviposited females to 1-Hz water currents generated by a model salamander with and without the placement of a transparent water current blocker between the model and the test females. The ovulated females responded to water currents by turning their heads toward, approaching, and/or making physical contact with the model. When the water current blocker was in place, the number of salamanders that approached the model was reduced significantly. The approaching and touching responses of ovulated females were greater than those of oviposited females, whereas the other measurements evidenced no differences. None of the responses of the oviposited females to water currents was affected by the presence of the blocker. Our results indicate that female H. leechii responds to water currents via a mechanosensory system.

• Elastomers and Composites
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• 제44권2호
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• pp.98-105
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• 2009

내이의 달팽이관은 기저막(basilar membrane)과 유모세포(hair cells)라는 두 가지 중요한 요소로 이루어져 있다. 기저막은 귀로 들어오는 소리를 주파수에 따라 분리하는 기능을 가지고 있으며, 기저막 위에 있는 유모세포는 생체전기 신호를 발생시키는 기계적 감각 수용기관이다. 인간의 생체청각기구를 모사한 인공와우와 신개념의 인공감각기관을 개발하기 위해서, 본 논문에서는 ZnO 압전 나노필라를 사용하여 인공유모세포(artificial hair cell)를 구현할 수 있는 핵심 기반 기술인 생체모사 기술을 연구하였다. 그 구체적인 방법으로 ZnO 나노필라를 저온성장법으로 유연기판에, 고온성장법으로 실리콘 웨이퍼에 성장시켰다. 유연기판과 실리콘 웨이퍼 위에 ZnO 나노필라를 성장 전에 미리 패턴을 만들었고, 기판에 선택적으로 ZnO 나노필라를 성장시켰다. 또한 ZnO 나노필라의 동적 정적 거동을 이해하기 위해 다중 물리 해석기법을 사용하여 ZnO 나노필라의 electric potential, von Mises stress, 변형량 등을 분석하였다. 본 연구에서는 ZnO 나노필라를 제작 및 패터닝하는 기술과 최적화하는 다중 물리 해석기술을 이용하여 인공 유모세포를 구현하는 핵심기술을 개발하였다.

• 약학회지
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• 제50권2호
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• pp.111-117
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• 2006

Cardiac chambers serve as mechanosensory systems during the haemodynamic or mechanical disturbances. To examine a possible role of fluid pressure (FP) in the regulatien of atrial $Ca^{2+}$ signaling we investigated the effect of FP on L-type $Ca^{2+}$ current $(I_{Ca})$ in rat ventricular myocytes using whole-cell patch-clamp technique. FP $(\sim40cm\;H_2O)$ was applied to whole area of single myocytes with electronically controlled micro-jet system. FP suppressed the magnitude of peak $I_{Ca}$ by $\cong25\%$ at 0 mV without changing voltage dependence of the current-voltage relationship. FP significantly accelerated slow component in inactivation of $I_{Ca}$, but not its fast component. Analysis of steady-state inactivation curve revealed a reduction of the number of $Ca^{2+}$ channels available for activity in the presence of FP. Dialysis of myocytes with high concentration of immobile $Ca^{2+}$ buffer partially attenuated the FP-induced suppression of $I_{Ca}$. In addition, the intracellular $Ca^{2+}$ buttering abolished the FP-induced acceleration of slow component in $I_{Ca}$ inactivation. These results indicate that FP sup-presses $Ca^{2+}$ currents, in part, by increasing cytosolic $Ca^{2+}$ concentration.