• The Journal of Asian Finance, Economics and Business
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• v.6 no.3
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• pp.103-113
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• 2019

The effectiveness of monetary policy critically depends upon how well the transmission mechanism functions, so that the desired impact on output and inflation is achieved. The purpose of this paper is to study the transmission mechanism of monetary policy by analyzing the impact on inflation and output during multiple indicator regime (1998-99 to 2014) in an emerging economy-India. The Inflation Targeting Regime is also briefly outlined alongwith the impact on output and inflation. Using quarterly data for the period 1997 to 2017, the paper uses weighted average call money market rate as a proxy for the policy rate and evaluates the strength of the interest rate channel. We use a conventional Structural vector auto regression (SVAR) methodology to evaluate the efficacy and show the impluse response functions. Our results find that changes in the policy rate impact output growth steeply with a lag of about two quarters and the impact on inflation is maximized after three quarters. The study concludes that the monetary policy in India has a significant impact on output and inflation in the short-to-medium-run. After the policy shock, the fall in the output growth rate is of greater magnitude than the fall in inflation.

• International Journal of Naval Architecture and Ocean Engineering
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• v.8 no.5
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• pp.423-433
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• 2016

In this paper, we consider the cybersecurity issue of ship information system (SIS) from a new perspective which is called opacity. For a SIS, its confidential information (named as "secret") may be leaked through the working behaviors of each Distributed Control Unit (DCU) from an outside observer called an "intruder" which is able to determine ship's mission state by detecting the source of each data flow from the corresponding DCUs in SIS. Therefore we proposed a dual layer mechanism to enforce opacity by activating non-essential DCU during secret mission. This mechanism is calculated by two types of insertion functions: Safety-assured insertion function ($f_{IS}$) and Admissibility-assured insertion function ($f_{IA}$). Due to different objectives, $f_{IS}$ is designed to confuse intruder by constructing a non-secret behaviors from a unsafe one, and the division of $f_{IA}$ is to polish the modified output behaviors back to normal. We define the property of "$I_2$-Enforceability" that dual layer insertion functions has the ability to enforce opacity. By a given mission map of SIS and the marked secret missions, we propose an algorithm to select $f_{IS}$ and compute its matchable $f_{IA}$ and then the DCUs which should be activated to release non-essential data flow in each step is calculable.

• Proceedings of the Technology Innovation Conference
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• 2003.06a
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• pp.108-115
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• 2003

Government R&D Project Management in Korea has had considerable difficulties because of the lack of project monitoring systems and insufficient communication. The National Program for Tera-level Nanodevices (TND Program) is a ten-year R&D program for commercialization in the area of nano technology. Collaboration and communication among the various participants such as business companies, universities, and government R&D institutes are key success factors in this R&D program. TND Program office has developed a Web-based project management system. This system consists of mostly four sub-management functions: (1) Milestones management of all R&D projects; (2) DR (Design Review) management as the mechanism for checking the performance against milestones; (3) Project activity management using the WBS (Work Breakdown Structure); (4) Budget management. Additionally, it also has many R&D supporting functions such as technology information bulletin board, community management, and visual summary of project progress and performance. This system is effective for monitoring research project as well as measuring project performance of the overall research program. This Web-based system has become the useful tool of R&D moving target mechanism and effective communication and collaboration tool. System features and adoption process of the system are also suggested.

• Journal of the Korean Society of Systems Engineering
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• v.2 no.1
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• pp.31-36
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• 2006

Development of launch vehicle needs a large-scale and complicated System Engineering discipline interfacing to small-quantity production with special manufacturing processes. In general, the System Engineering discipline of launch vehicle has its relationship with Production, Operations, Product Assurance and Management disciplines and its internal partitions into the functions of System Engineering Integration & Control, Requirements Engineering, Analysis, Design and Configuration and Verification. As a function of Product Assurance, reliability of launch vehicle plays an significant role in risk management, system safety, flight safety and launch certification through design assurance. Moreover, major functions of systems engineering are integrated by means of reliability in the phases of design and verification. Therefore, derailed identification of system engineering interfaces of reliability, and execution of tasks for reliability assurance is required for successful development of launch vehicle. This paper identifies specific pattern and mechanism of the interfaces between reliability and system engineering.

• Proceedings of the KIEE Conference
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• 2003.07b
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• pp.1111-1113
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• 2003

This paper proposes an effective self-turning algorithm based on Artificial Neural Network (ANN) for fuzzy speed control of the indirect vector controlled induction motor. Indirect vector control method divides and controls stator current by the flux and the torque producing current so that the dynamic characteristic of induction motor may be superior. However, if motor parameter changes, the flux current and the torque producing one's coupling happens and deteriorates the dynamic characteristic. The fuzzy speed controller of an induction motor has the robustness over the effect of this parameter variation than a conventional PI speed controller in some degree. This paper improves its adaptability by adding the self-tuning mechanism to the fuzzy controller. For tracking the speed command, its membership functions are adjusted using ANN adaptation mechanism. This adaptability could be embodied by moving the center positions of the membership functions. Proposed self-tuning method has wide adaptability than existent fuzzy controller or PI controller and is proved robust about parameter variation through Matlab/Simulink simulation.

• Journal of Korea Multimedia Society
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• v.24 no.10
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• pp.1380-1390
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• 2021

The video face recognition (FR) is one of the most popular researches in the field of computer vision due to a variety of applications. In particular, research using the attention mechanism is being actively conducted. In video face recognition, attention represents where to focus on by using the input value of the whole or a specific region, or which frame to focus on when there are many frames. In this paper, we propose a novel attention based deep learning method. Main novelties of our method are (1) the use of combining two loss functions, namely weighted Softmax loss function and a Triplet loss function and (2) the feasibility of end-to-end learning which includes the feature embedding network and attention weight computation. The feature embedding network has a positive effect on the attention weight computation by using combined loss function and end-to-end learning. To demonstrate the effectiveness of our proposed method, extensive and comparative experiments have been carried out to evaluate our method on IJB-A dataset with their standard evaluation protocols. Our proposed method represented better or comparable recognition rate compared to other state-of-the-art video FR methods.

• IMMUNE NETWORK
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• v.23 no.2
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• pp.12.1-12.17
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• 2023

Ssu72, a dual-specificity protein phosphatase, not only participates in transcription biogenesis, but also affects pathophysiological functions in a tissue-specific manner. Recently, it has been shown that Ssu72 is required for T cell differentiation and function by controlling multiple immune receptor-mediated signals, including TCR and several cytokine receptor signaling pathways. Ssu72 deficiency in T cells is associated with impaired fine-tuning of receptor-mediated signaling and a defect in CD4⁺ T cell homeostasis, resulting in immune-mediated diseases. However, the mechanism by which Ssu72 in T cells integrates the pathophysiology of multiple immune-mediated diseases is still poorly elucidated. In this review, we will focus on the immunoregulatory mechanism of Ssu72 phosphatase in CD4⁺ T cell differentiation, activation, and phenotypic function. We will also discuss the current understanding of the correlation between Ssu72 in T cells and pathological functions which suggests that Ssu72 might be a therapeutic target in autoimmune disorders and other diseases.

• BMB Reports
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• v.57 no.6
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• pp.263-272
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• 2024

Amyloid-β (Aβ) is one of the amyloidogenic intrinsically disordered proteins (IDPs) that self-assemble to protein aggregates, incurring cell malfunction and cytotoxicity. While Aβ has been known to regulate multiple physiological functions, such as enhancing synaptic functions, aiding in the recovery of the blood-brain barrier/brain injury, and exhibiting tumor suppression/antimicrobial activities, the hydrophobicity of the primary structure promotes pathological aggregations that are closely associated with the onset of Alzheimer's disease (AD). Aβ proteins consist of multiple isoforms with 37-43 amino acid residues that are produced by the cleavage of amyloid-β precursor protein (APP). The hydrolytic products of APP are secreted to the extracellular regions of neuronal cells. Aβ 1-42 (Aβ42) and Aβ 1-40 (Aβ40) are dominant isoforms whose significance in AD pathogenesis has been highlighted in numerous studies to understand the molecular mechanism and develop AD diagnosis and therapeutic strategies. In this review, we focus on the differences between Aβ42 and Aβ40 in the molecular mechanism of amyloid aggregations mediated by the two additional residues (Ile41 and Ala42) of Aβ42. The current comprehension of Aβ42 and Aβ40 in AD progression is outlined, together with the structural features of Aβ42/Aβ40 amyloid fibrils, and the aggregation mechanisms of Aβ42/Aβ40. Furthermore, the impact of the heterogeneous distribution of Aβ isoforms during amyloid aggregations is discussed in the system mimicking the coexistence of Aβ42 and Aβ40 in human cerebrospinal fluid (CSF) and plasma.

• Journal of Information Technology Services
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• v.16 no.1
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• pp.73-82
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• 2017

Recently in-memory data stream processing has been actively applied to various subjects such as query processing, OLAP, data mining, i.e., frequent item sets, association rules, clustering. However, finding regular periodic patterns of events in an infinite data stream gets less attention. Most researches about finding periods use autocorrelation functions to find certain changes in periodic patterns, not period itself. And they usually find periodic patterns in time-series databases, not in data streams. Literally a period means the length or era of time that some phenomenon recur in a certain time interval. However in real applications a data set indeed evolves with tiny differences as time elapses. This kind of a period is called as a pseudo-period. This paper proposes a new scheme called FPMH (Finding Periods using Multiple Hash functions) algorithm to find such a set of pseudo-periods over a data stream based on multiple hash functions. According to the type of pseudo period, this paper categorizes FPMH into three, FPMH-E, FPMH-PC, FPMH-PP. To maximize the performance of the algorithm in the data stream environment and to keep most recent periodic patterns in memory, we applied decay mechanism to FPMH algorithms. FPMH algorithm minimizes the usage of memory as well as processing time with acceptable accuracy.

• Molecules and Cells
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• v.44 no.5
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• pp.342-355
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• 2021

The microphthalmia-associated transcription factor family (MiT family) proteins are evolutionarily conserved transcription factors that perform many essential biological functions. In mammals, the MiT family consists of MITF (microphthalmia-associated transcription factor or melanocyte-inducing transcription factor), TFEB (transcription factor EB), TFE3 (transcription factor E3), and TFEC (transcription factor EC). These transcriptional factors belong to the basic helix-loop-helix-leucine zipper (bHLH-LZ) transcription factor family and bind the E-box DNA motifs in the promoter regions of target genes to enhance transcription. The best studied functions of MiT proteins include lysosome biogenesis and autophagy induction. In addition, they modulate cellular metabolism, mitochondria dynamics, and various stress responses. The control of nuclear localization via phosphorylation and dephosphorylation serves as the primary regulatory mechanism for MiT family proteins, and several kinases and phosphatases have been identified to directly determine the transcriptional activities of MiT proteins. In different immune cell types, each MiT family member is shown to play distinct or redundant roles and we expect that there is far more to learn about their functions and regulatory mechanisms in host defense and inflammatory responses.