• Journal of Life Science
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• v.25 no.5
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• pp.585-593
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• 2015

Stress fiber (SF) alteration is mediated by cellular receptors, which, upon interaction with the extracellular counterpart, signal to the actin cytoskeleton for remodeling. This association is mediated by a variety of scaffold and signaling factors, which control the mechanical and signaling activities of the interaction site. The heterotrimeric transmembrane lymphotoxin α1β2 (LTα1β2), a member of the tumor necrosis factor (TNF) family of cytokines, including soluble homotrimeric lymphotoxin (LT α), plays an important role in lymphoid tissue architecture. Ligation between LTα1β2 and the lymphotoxin β receptor (LTβR) activates signal-cascade in fibroblastic reticular cells (FRCs). We found LTβR stimulation using an agonistic anti-LTβR antibody alone or combined with LTα or TNFα induced changes in the actin and plasticity of cells. To clarify the involvement of myosin underlying the alteration, we analyzed the effect of myosin light chain kinase (MLCK) with an MLCK inhibitor (ML7), the phosphorylation level of myosin light chains (MLC), and the level of phospho-myosin phosphatase target subunit 1 (MYPT1) after treatment with an agonistic anti-LTβR antibody for cytoskeleton reorganization in FRCs. The inhibition of MLCK activity induced changes in the actin cytoskeleton organization and cell morphology in FRC. In addition, we showed the phosphorylation of MLC and MYPT1 was reduced by LTβR stimulation in cells. A DNA chip revealed the LTβR stimulation of FRC down-regulated transcripts of myosin and actin components. Collectively, these results suggest LTβR stimulation is linked to myosin regarding SF alteration in FRC.

• Journal of Radiation Protection and Research
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• v.31 no.1
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• pp.37-46
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• 2006

For the first step to develop a reference disposal container of spent fuel to be used in a deep geological repository, this paper examined safe dimensions of the disposal container on the points of nuclear criticality and radiation safety and mechanical structural safety and provided basic information for dimensioning the container and configuration of the container components, and establishing the favorable and safe disposal conditions. When the safety factor for stress due to the external loads (hydrostatic and swelling pressure) is taken as 2.0, the safe diameter of the filler material to provide enough container strength under the assumed external loads is found to be 112cm with 13cm spacing between inner baskets in PWR container. Also the thickness of the thinner section between the fuel basket and the surface of the cast insert is determined to be 150 mm. Regarding these dimensions of the container, the PWR fuel container is sketched to accommodate 4 square assemblies or 297 CANDU fuel 297 bundles (33 circle tubes x 9 stacks). However the top and bottom parts need to be checked again through the detail radiation shielding analysis with respects to the emplacement position and handling processes of the disposal container.

• Korean journal of food and cookery science
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• v.22 no.6 s.96
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• pp.849-854
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• 2006

The objective of this study was to evaluate the quality characteristics of Dotoridasik prepared by the addition of acorn powder (0%, 20%, 40%, 60%, 80%). The Proximate components were 85.89% carbohydrate, 1.38% crude fat, 0.84% crude protein and 0.32% crude ash. The moisture content of Dotoridasik showed no significant difference between the added acorn powder and control groups. The following Hunter color values are not part of the sensory evaluation testing in the results of for Dotoridasik, decreased while the a and b values increased with increasing acorn powder addition. The bitter taste was evaluated as being improved with increasing acorn powder addition. Dotoridasik with 40% acorn powder showed the highest acceptance. In the mechanical evaluation, hardness recording which from control Will increase with acorn powder it shows a high shame(p<0.05), the adhesiveness result springiness it was not visible a consider difference especially also utterly unintelligible).

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.39 no.5
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• pp.11-20
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• 2002

Based on regularization principles, we propose a new dequantization scheme on DCT-based transform coding for reducing of blocking artifacts and minimizing the quantization error. The conventional image dequantization is simply to multiply the received quantized DCT coefficients by the quantization matrix. Therefore, for each DCT coefficients, we premise that the quantization noise is as large as half quantizer step size (in DCT domain). Our approach is based on basic constraint that quantization error is bounded to ${\pm}$(quantizer spacing/2) and at least there are not high frequency components corresponding to discontinuities across block boundaries of the images. Through regularization, our proposed dequantization scheme, sharply reduces blocking artifacts in decoded images. Our proposed algorithm guarantees that the dequantization process will map the quantized DCT coefficients will be evaluated against the standard JPEG, MPEG-1 and H.263 (with Annex J deblocking filter) decoding process. The experimental results will show visual improvements as well as numerical improvements in terms of the peak-signal-to-noise ratio (PSNR) and the blockiness measure (BM) to be defined.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.1
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• pp.52.2-52.2
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• 2014

The Immersion Grating Infrared Spectrometer (IGRINS) is an unprecedentedly minimized infrared cross-dispersed echelle spectrograph with a high-resolution and high-sensitivity optical performance. A silicon immersion grating features the instrument for the first time in this field. IGRINS will cover the entire portion of the wavelength range between 1.45 and $2.45{\mu}m$ accessible from the ground in a single exposure with spectral resolution of 40,000. Individual volume phase holographic (VPH) gratings serve as cross-dispersing elements for separate spectrograph arms covering the H and K bands. On the 2.7m Harlan J. Smith telescope at the McDonald Observatory, the slit size is $1^{\prime\prime}{\times}15^{\prime\prime}$. IGRINS has a $0.27^{\prime\prime}$ pixel-1 plate scale on a $2048{\times}2048$ pixel Teledyne Scientific & Imaging HAWAII-2RG detector with SIDECAR ASIC cryogenic controller. The instrument includes four subsystems; a calibration unit, an input relay optics module, a slit-viewing camera, and nearly identical H and K spectrograph modules. The use of a silicon immersion grating and a compact white pupil design allows the spectrograph collimated beam size to be 25mm, which permits the entire cryogenic system to be contained in a moderately sized rectangular vacuum chamber. The fabrication and assembly of the optical and mechanical hardware components were completed in 2013. In this presentation, we describe the major design characteristics of the instrument and the early performance estimated from the first light commissioning at the McDonald Observatory.

• The Journal of Korean Academy of Prosthodontics
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• v.45 no.6
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• pp.780-786
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• 2007

Statement of problem. The performance and maintenance of implant-supported prostheses are primarily dependent upon load transmission both at the bone-to-implant interface and within the implant-abutment-prosthesis complex. The design of the interface between components has been shown to have a profound influence on the stability of screw joints. Purpose. The Purpose of this study was to compare the strength and the fatigue resistance of 1-piece and 2-piece abutment connected to oral implant, utilizing an internal conical interface. Material and methods. Twenty $Implatium^{(R)}$ tapered implants were embedded to the top of the fixture in acrylic resin blocks. Ten $Combi^{(R)}$(1-piece) and $Dual^{(R)}$(2-piece) abutments of the same dimension were assembled to the implant, respectively. The assembled units were mounted in a testing machine. A load was applied perpendicular to the long axis of the assemblies and the loading points was at the distance of 7mm from the block surface. Half of 1-piece and 2-piece abutment-implant units were tested for the evaluation of the bending strength, and the others were cyclically loaded for the evaluation of the fatigue resistance until plastic deformation occurred. Nonparametric statistical analysis was performed for the results. Results. Mean plastic and maximum bending moment were $1,900{\pm}18Nmm,\;3,609{\pm}106Nmm$ for the 1-piece abutment, and $1,250{\pm}31Nmm,\;2,688{\pm}166Nmm$ for the 2-piece abutment, respectively. Mean cycles and standard deviation when implant-abutment joint showed a first plastic deformation were $238,610{\pm}44,891$. cycles for the 1-piece abutment and $9,476{\pm}3,541$ cycles for the 2-piece abutment. A 1-piece abutment showed significantly higher value than a 2-piece abutment in the first plastic bending moment (p<.05), maximum bending moment (p<.05) and fatigue strength (p<.05). Conclusion. Both 1-piece and 2-piece conical abutment had high strength and fatigue resistance and this suggests long-term durability without mechanical complication. However, the 1-piece conical abutment was more stable than the 2-piece conical abutment in the strength and the fatigue resistance.

• Clean Technology
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• v.13 no.2
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• pp.151-158
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• 2007

An experimental study to investigate the condensing heat transfer characteristics of small diameter horizontal double pipe heat exchangers with R-22 and R-410A was performed. Experimental facility was constructed to calculate and observe HTC(heat transfer coefficients), flow patterns and pressure drop. The main components include a liquid pump, an evaporator, a condenser(test section), a sight-glass, pressure taps and measurement apparatus. Two pipes of different diameters are tested; One 5.35 mm ID 0.5 mm thick, the other 3.36 mm ID 0.7 mm thick. The mass flow rate ranged from 200 to $500\;ks/m^2{\cdot}s$ and heating capacity were form 1.0 to 2.4 kW. The flow patterns of R-22 and R-410A were observed with a high speed camera through the sight-glass. The tests revealed that HTC of R-410A was higher than that of R-22 by maximum 5%. Annular pattern was observed for the most cases but stratified flow was also detected when x<0.2. The pressure drop in 3.36 mm ID pipe was higher than that of 5.35 mm by $30{\sim}50%$. Comparing with previous correlations such as Shah, Fujii and Soliman's, Fujii' showed the best good agreement with my data with a maximum deviation of 40%.

• Korean Journal of Optics and Photonics
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• v.24 no.5
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• pp.231-236
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• 2013

We investigated the optical design of a smart headlamp capable of producing various beam patterns through only on/off modulation of light sources. This was implemented by forming a continuous matrix of beams from discontinuous beam patterns by means of a multi-array LED optical system. As one such optical system, the multi-array LED system is a convenient and economical device for implementing beam patterns with the simple on/off modulation of the light sources. A single optical assembly module can be made by combining a multiple-LED array, optical system module, and electronic control with no need for any additional mechanical components. The present optical system was designed to include a secondary lens and a projection lens mounted at the front of each LED in the array to realize accurate lighting patterns as well as the required luminosity at a distance of 25 m in the forward direction. Finally, we identified and analyzed the patterns implemented by the designed optical system that produced satisfactory performance of high beams and adaptive driving beams (ADB).

• The Journal of Korean Academy of Prosthodontics
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• v.49 no.2
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• pp.106-113
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• 2011

The object of this clinical study was to evaluate the short-term outcome of modified resin-bonded fixed partial dentures which utilizes the original tooth undercuts and different path of insertion of components. Materials and methods: 71 units of modified RBFPDs that were used in 21 patients at the Department of Prosthodontics, College of Dentistry, Yonsei University were evaluated. The follow-up period was up to 25 months, the mean being 7 months. Survival rate, mobility, percussion, probing depth, bleeding on probing, plaque index was recorded and radiographs were taken to monitor alveolar bone loss. Results & Conclusion: Within the limits of this short term retrospective study, it was concluded that: 1. No mechanical failure such as debonding or fracture of the framework was found during the follow-up period. 2. The periodontal apparatus was stable and no clinical change was observed after prosthetic treatment. 3. No significant marginal bone loss was found in the radiographic evaluation.

• Restorative Dentistry and Endodontics
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• v.33 no.4
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• pp.377-388
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• 2008

The aim of the present study is to compare the corrosion tendency using two kinds of NiTi files in the various environmental conditions through the visual examination and electrochemical analysis. ProTaper Universal S2, 21 mm (Dentsply Maillefer, Ballaigues, Switzerland) and Hero 642, 0.06 tapers, size 25, 21 mm (Micromega, Besancon, France) rotary instruments were tested. The instruments were randomly divided into eighteen groups (n = 5) by the immersion temperature, the type of solution, the brand of NiTi rotary instrument and the presence of mechanical loading. Each file was examined at various magnifications using Scanning Electron Microscope (JEOL, Akishima, Tokyo, Japan) equipped with energy dispersive X-ray microanalysis (EDX). EDX was used to determine the components of the endodontic file alloy in corroded and noncorroded areas. The corrosion resistance of unused and used NiTi files after repeated uses in the human teeth was evaluated electrochemically by potentiodynamic polarization test using a potentiostat (Applied Corrosion Monitoring, Cark-in-Cartmel, UK). Solution temperature and chloride ion concentration may affect on passivity of NiTi files. Under the conditions of this in vitro study, the corrosion resistance is slightly increased after clinical use.