• 한국한의학연구원논문집
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• 제18권1호
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• pp.59-74
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• 2012

Objective : The aim of this study is to investigate current status of Sasang constitutional medicine researches and to provide source in setting a development strategy and making a policy on the Sasang constitutional medicine. Method : This study analyzed trends in research as represented in the 142 articles of Korea Institute of Oriental Medicine in the field of Sasang constitution medicine from 2007 to 2010. Result : The main themes of studies were Sasang constitution clinical study (68, 47%) and developing instruments for measuring diagnosis (48, 33%), especially pulse diagnosis (25, 17%). Genetic researches and trends studies on Sasang constitutional medicine were respectively 17 (12%) and 8 (5%). As a result, Korea Institute of Oriental Medicine established Sasang clinical information bank, and discovered clinical character of Sasang constitution to develope various diagnosis tools include constitution survey form and pulse diagnosis instrument. Genetic researches also discover constitution related genes such as FTO and MC4R, and explore association between heredity and Sasang constitution. Conclusion : The above mentioned achievements of Korea Institute of Oriental Medicine were limited to diagnosis process, unquestionably studies for reproducibility and authenticity of constitution diagnosis were important mission of Sasang constitutional medicine. However, to develop the advance of Sasang constitutional medicine, not only constitution diagnosis but also constitutional treatment studies should be conducted.

• BMB Reports
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• 제44권11호
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• pp.735-740
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• 2011

Tunicamycin, an endoplasmic reticulum (ER) stress inducer, specifically inhibits N-glycosylation. The cyclic AMP (cAMP) response element-binding protein H (CREBH) was previously shown to be regulated by UPR-dependent proteolytic cleavage in the liver. On the other hand, the role of CREBH in other tissues is unknown. In the present study, tunicamycin increased the level of CREBH activation (cleavage) as well as mRNA expression in osteoblast cells. Adenoviral (Ad) overexpression of CREBH suppressed BMP2-induced expression of alkaline phosphatase (ALP) and osteocalcin (OC). Interestingly, the BMP2-induced OASIS (structurally similar to CREBH, a positive regulator of osteoblast differentiation) expression was also inhibited by CREBH overexpression. In addition, inhibition of CREBH expression using siRNA reversed the tunicamycin-suppressed ALP and OC expression. These results suggest that CREBH inhibited osteoblast differentiation via suppressing BMP2-induced ALP, OC and OASIS expression in mouse calvarial derived osteoblasts.

• 한국태양에너지학회:학술대회논문집
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• 한국태양에너지학회 2011년도 춘계학술발표대회 논문집
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• pp.293-298
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• 2011

The most widely used method to form an electrode in industrial solar cells are screen printing. Screen printing is characterized by a relatively simple and well-known production sequence with high throughput rates. However the method is difficult to implement a fine line width of high-efficiency solar cells can not be made. The open circuit voltage(Voc) and the short circuit current density(Jsc) and fill factor(FF) need to be further improved to increase the efficiency of silicon solar cells. In this study, gravure offset printing method using the multicrystalline-silicon solar cells were fabricated. Gravure off-set printing method which can print the fine line width of finger electrode can have the ability reduce the shaded area and increase the Jsc. Moreover it can make a high aspect ratio thereby series resistance is reduced and FF is increased. Approximately $50{\mu}m$ line width with $35{\mu}m$ height was achieved. The efficiency of gravure off set was 0.7% higher compare to that of scree printing method.

• 대한한방부인과학회지
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• 제35권3호
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• pp.137-149
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• 2022

Objectives: The purpose of this study is to report the effect of Korean medicine treatment in a patient with Herpes Zoster (HZ) during pregnancy. Methods: During 12 days of hospitalization, a patient was treated by Korean medicine treatment such as herbal medicine including Gami-danggui-san, acupuncture, cupping and fumigation. To evaluate the effect of treatment, we took pictures of skin lesion and symptoms were measured by Numeric Rating Scale (NRS), Short-Form McGill Pain Questionnaire (SF-MPQ) and 36 item Short Form Health Survey (SF-36). Results: After Korean medicine treatment, most of vesicles disappeared. NRS of chief complaints such as neuralgic pain and itchness changed 7-8 to 0 and therefore, quality of life of the patient was elevated sharply. Conclusions: This case shows that Korean medicine treatment is beneficial and safe for the patients who suffered from Herpes Zoster during pregnancy.

• 대한지리학회지
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• 제41권2호
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• pp.150-167
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• 2006

이 연구는 미국 위스콘신 남부지방의 뢰스(loess)로 덮여있는 빙퇴석평야상의 소규모 저습지와 산록부에서 관찰되는 치밀차표층(dense subsurface horizons)의 형성원인과 형성과정을 설명하기 위한 것이다. 연구대상이 된 치밀차표층은 Bd 혹은 Bx층으로 명명될 수 있는 토양층이다. 일부 치밀차표층은 형태적으로 이쇄반층(fragipan, Bx)과 매우 유사한 특징을 보이지만, 아직까지 주변지역에서 이쇄반층의 존재가 보고된 바는 없다. 이 연구에서는 치밀차표층과 이쇄반층의 상대적인 분포의 차이를 지형기복과의 관계를 통해 관찰하였으며, 그 형성원인을 파악하기 위해 물리 화학적 분석과 더불어 토양구조의 현미경 관찰을 실시하였다. 그 결과 이쇄반층의 형성은 토양구조의 물리적인 숙성과정(physical ripening)과 그에 이은 콜로이드물질의 집적과정을 거치면서 형성된 것으로 결론을 내렸다. 치밀차표층에서 관찰되는 높은 밀도의 토양매질은 빙하가 물러나면서 형성된 소규모 빙하호수와 범람원에 퇴적된 뢰스물질들이 물리적인 숙성과정(physical ripening)을 거치면서 형성된 것으로 보이며, 그 결과 대규모의 주상구조(prismatic structure)가 형성되었다. 이후 지속적인 토양화과정을 거치면서 Si를 포함하는 콜로이드 물질의 집적에 의해 토양매질이 더욱 단단해지는 과정을 거치게 되면서 이쇄반층으로 발전하게 되었다. Si의 집적정도는 지형적인 특성과 물의 흐름에 의해 결정되게 된다. 물과 물질의 집적이 주로 나타나는 소규모의 저습지에서는 Si의 집적으로 인해 잘 발달된 이쇄반층(Bx)이 발달하게 된다. 반면, Si의 제거가 비교적 활발하게 이루어지는 산록부에서는 이쇄반층의 단계로 발전하지 못하고 치밀층(Bd)에 머물고 있는 것으로 판단된다. 이쇄반층이 만들어진 경우에는 그 상부에 불투수층이 형성되어, 물리적 숙성과정으로 형성된 주상구조의 상부가 서서히 파괴되는 현상을 보기에 된다. 이 경우에는 이쇄반층 상부에 용탈이쇄반층 (eluvial fragic horizon, Ex)이 나타나게 된다.

• 한방재활의학과학회지
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• 제27권3호
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• pp.137-146
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• 2017

Objectives The purpose of this study is to compare the effects between the KL-Grade and improvement of knee pain treated by Korean Medicine therapy. Methods 114 patients who received inpatient treatment from July 2014 to May 2017 in the Daejeon Jaseng of Korean Medicine Hospital were divided into 5 groups by the KL-Grade. All patients received a combination of treatment including acupunture, pharmacopunture, herbal medication. They were compared and analyzed on the basis of improvement between measuring Numeric Rating Scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC Index), EuroQol-5 Dimension Index (EQ-5D Index) as they were hospitalized and as they were discharged. The statistically significance was evaluated by SPSS 23.0 for windows. Results After treatment, KL-Grade 0 group's Numeric Rating Scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC Index), EuroQol-5 Dimension Index (EQ-5D Index) improvement was $2.02{\pm}1.69$, $7.50{\pm}9.67$ and $0.11{\pm}0.15$ respectively. KL-Grade 1 group's improvement was $2.09{\pm}1.23$, $11.75{\pm}13.99$ and $0.12{\pm}0.13$ respectively. KL-Grade 2 group's improvement was $1.60{\pm}1.07$ and $14.70{\pm}14.19$ respectively. But In this group, EQ-5D Index has decreased by $0.01{\pm}0.10$. KL-Grade 3 group's improvement was $1.88{\pm}1.31$, $7.81{\pm}13.35$ and $0.13{\pm}0.20$ respectively (p<0.034). In the case of KL-Grade 4, the population was not statistically significant (N=2) and therefore excluded from statistical significance. And there was no statistically significance between 4 group's improvement after treatment (p>0.05). Conclusions The above study showed that Korean medicine treatments showed significant therapeutic effects on knee pain and degenerative knee joints, but there was no significant difference in the effectiveness of degenerative arthritis (KL-Grade).

• 공업화학
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• 제31권3호
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• pp.267-276
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• 2020

Oxirane계 단량체의 양이온 개환 공중합반응으로 합성되는 ECH (ephichorohydrin) 기반 copolyol (PECH copolyol)류의 특성에 대한 반응온도, 용매의 종류 및 개시제에 대한 영향을 연구하였다. 공단량체로는 butylene oxide와 hexylene oxide 두 종류의 알킬렌 옥사이드를 사용하였으며, 중합 조건은 methylene chloride (MC) 용매에서 개시제로 diethylene glycol (DEG)를 사용한 조건과 toluene을 용매에서 tripropylene glycol (TPG)를 개시제로 사용한 두 조건으로 진행하였다. 개환 공중합반응에서 active monomer (AM) mechanism 유도를 위해 단량체는 실린지 펌프를 사용해 IMA (increased monomer addition) 방법으로 주입하였고 중합온도는 -5 ℃에서 실행하였다. 합성된 ephichorohydrin (ECH) 기반 copolyol인 PECH copolyol은 치환반응으로 ECH unit를 아지드화하여 glycidyl azide계 에너지 함유 copolyol (GAP copolyol)로 전환하였다. 합성된 아지드화 코폴리올은 용매와 개시제의 변화에 대한 영향은 크지 않았으며, 분자량은 아지드화 반응 후 평균 500 증가함으로써 GAP 코폴리올이 설계한 대로 중합되었음을 확인하였다. DSC 분석으로 copolyol류의 조성비 변화에 따른 유리전이 온도(glass transition temperature, T_g)의 변화를 측정하였을 때, 공단량체의 함량이 증가할수록 알킬 사슬의 길이에 의한 영향으로 T_g와 점도가 모두 감소하는 경향을 보였다. 아지드화 반응과정에서 생성되는 CH₃N₃의 생성을 원천적으로 방지할 수 있으며, 대규모 공정이 가능할 것으로 기대된다.

• 대한본초학회지
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• 제28권2호
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• pp.75-82
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• 2013

Objective : This study was to evaluate the effectiveness of the prescription Dokhwalkigisaengtangagambang(DGG) and Gamisayuktanggagambang(GSG), which has been utilized in the treatment of joint disease, for improving low back and knee joint pain. Methods : In the patients for the clinical studies, control group was 28 cases, experimental group was 41 cases. All subjects had low back pain and knee pain. The experimental group was treated with DGG or GSG, the control group was treated with 17 prescriptions. VAS (Visual Analag Scale), WOMAC (Western Ontario and McMasters Universties Osteoarthritis Index) and ODI (Oswestry Low back pain Disability index) measured before and after the prescription administration. Results : In the difference of VAS score, the experimental group (p <0.001) and the control group (p <0.001) were decreased significantly before and after the administration of prescription, and in the comparisons between the experimental group and the control group, experimental group was decreased significantly compared to the control group(p = 0.008). In the WOMAC score, there was no significant difference between the experimental group and the control group. In the difference of ODI items score, lifting (p = 0.020) and sleeping (p = 0.028) index were decreased significantly before and after the administration of prescription. Conclusion : The results indicated that the prescription DGG and GSG can reduce knee pain and low back pain. This study will be helpful for improving joint disease.

• Journal of Radiation Protection and Research
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• 제21권4호
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• pp.255-262
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• 1996

이 논문은 최근 한국원자력연구소(KAERI)와 미국 패시픽노스웨스트 국립연구소(일명, 바텔연구소, PNNL)이 개인선량계의 성능검사를 위한 미국 ANSI N13.11 기준에 근거하여 KAERI 방사선 측정/교정실험실에서 수행한 KAERI 기준 광자 및 베타 방사선장의 국제 상호비교 측정결과를 설명하고 있다. 두 기관이 각각 자국의 일차 표준에 소급성을 갖는 방사선 검출기와 방사선 측정장치를 사용하여 자유공기중에서 광자의 조사선량(율), 공기커마(율)와 베타선의 절대 흡수선량(율)을 측정한 결과, 광자선장에 대해서는 ${\pm}2.0%$을 베타선장에 대해서는${\pm}1.0%$의 오차범위 내에서 잘 일치하였다. 따라서 KAERI의 기준 광자 및 베타 방사선장은 국제표준에 잘 만족되고 있음이 입증되었으며 장차 방사선 도시메트리 연구개발의 국가 기술기반으로 활용될 수 있음이 확인되었다

• 신재생에너지
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• 제9권2호
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• pp.30-39
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• 2013

Multi-crystalline silicon solar cells is not exist a specific crystal direction different from single crystalline silicon solar cells. In functional materials, therefore, isotropic wet etching of mc-Si solar cell is easy the acid solution rather than the alkaline solution. The reflectance of wet texturing process is about 25% and the reflectance of RIE texturing process is achieved less than 10%. In addition, wet texturing has many disadvantages as well as reflectance. So wet texturing process has been replaced by a RIE texturing process. In order to apply BIPV, RIE and wet textured multi-crystalline silicon solar cell modules was manufactured by different kind of EVA sheet. Moreover, in case of BIPV, the short circuit current characteristics according to the angle of incidence is more important, because the installation of BIPV is fixed location. In this study, we has measured SEM image and I-V curve of RIE and wet textured silicon solar cell and PV module. Also we has analyzed quantum efficiency characteristics of RIE and wet textured silicon solar cell for PV modules depending on incidence angle.