• BMB Reports
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• v.56 no.8
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• pp.426-438
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• 2023

Muscle wasting in end-stage renal disease (ESRD) is an escalating issue due to the increasing global prevalence of ESRD and its significant clinical impact, including a close association with elevated mortality risk. The phenomenon of muscle wasting in ESRD, which exceeds the rate of muscle loss observed in the normal aging process, arises from multifactorial processes. This review paper aims to provide a comprehensive understanding of muscle wasting in ESRD, covering its epidemiology, underlying molecular mechanisms, and current and emerging therapeutic interventions. It delves into the assessment techniques for muscle mass and function, before exploring the intricate metabolic and molecular pathways that lead to muscle atrophy in ESRD patients. We further discuss various strategies to mitigate muscle wasting, including nutritional, pharmacological, exercise, and physical modalities intervention. This review seeks to provide a solid foundation for future research in this area, fostering a deeper understanding of muscle wasting in ESRD, and paving the way for the development of novel strategies to improve patient outcomes.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.8 no.1
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• pp.69-75
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• 1988

Two rational formulae depicting the relationships between sludge ages and recycle flow rates have been developed to determine sludge wasting volumes at a particular sludge age. A sensitivity analysis shows that the recycle ratio is the most important variable to be measured as accurately as possible in determining the sludge wasting volume to maintain a particular sludge age when the system is controlled by wasting recycled sludge. On the other hand, the final clarifier solids capturing capacity is the most important variable to be measured when the system is operated by wasting mixed liquor.

• Ocean and Polar Research
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• v.24 no.4
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• pp.483-490
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• 2002

Detailed investigations on both submarine and subaerial volcaniclastic deposits around Dokdo were carried out to identify geomorphologic characteristics, stratigraphy, and associated depositional processes of Dokdo caldera. Dokdo volcano has a gently sloping summit (about 11km in diameter) and relatively steep slope (basal diameter is about 20-25 km) rising above sea level at about 2,270m. We found ragged, elliptical-form of Dokdo caldera with a diameter of about 2km estimated by Chirp (3-11 kHz) sub-bottom profile data and side scan sonar data for the central summit area of Dokdo volcano. We interpreted that the volcaniclastic deposits of Dokdo unconformably consist of the Seodo (west islet) and the Dongdo(east islet) formations based on internal structure, constituent mineral composition, and bedding morphology. The Seodo Formation mainly consisted of massive or inversely graded trachytic breccias (Unit S-I), overlain by fine-grained tuff (Unit S-II), which is probably supplied by mass-wasting processes resulting from Dokdo caldera collapse. The Dongdo Formation consists of alternated units of stratified lapilli tuff and inversely graded basaltic breccia (Unit D-I, Unit D-III, and Unit D-V), and massive to undulatory-bedded basaltic tuff breccias (Unit D-II and Unit D-IV) formed by a repetitive pyroclastic surge and reworking processes. Although, two islets of Dokdo are geographically near each other, they have different formations reflecting their different depositional processes and eruptive stages.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.7 no.3
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• pp.148-156
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• 2002

The coastline of Hampyung Bay, southwestern coast of Korea, was examined and measured in the field for the understanding of geomorphic changes and sea-cliff erosion processes. The Hampyung-Bay coastline is characterized by steep-face slope and soft soil and/or intensively weathered rock composition. Saw teeth-shaped coastline, and relict weathered basement-rock and "Island Stack" exposed on the beach surface are peculiar geomorphic features indicating active sea-cliff erosion. The coastline in the study area is continuously retreating with the following cyclic process: erosion of cliff base, gravitational landslide or mass wasting, formation of talus, and then erosion and removal of talus. In this study, sea-level rise during summer in the west coast of Korea is suggested as one of the key factors fur the removal of soil taluses and, thereby, accelerating sea-cliff erosion.f erosion.