• 대한간호학회지
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• 제23권2호
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• pp.207-223
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• 1993

Inpatients are mostly occupied in bed with restricted activity, nearly all patient populations are at risk for the occurrence of skeletal muscle atrophy due to decreased level of activity. Restriction of mobility is far greater in pediatric patients compared with adult patients since almost all the activities of daily living is performed by parents or caregivers. It could be assumed that pediatric patients are more vulnerable to skeletal muscle atrophy than adult patients, however, there have been no attempts to reduce the atrophy of developing muscle. Therefore it is important to determine the effect of exercise in developing muscle during decreased activity. The purpose of this study was to determine the effect of periodic weight support during hindlimb suspension on the mass and cross-sectional area of Type I and II fibers in developing soleus(Type I ) muscle. To examine the effectiveness of periodic weight support activity in maintaining mass and fiber size. the hindlimb of young female Wistar rats was suspended(HS) and half of these rats walked on a treadmill for 45min / day(15min every 4h) at 5m / min at a 15 grade(HS-WS). After 7days of hindlimb suspension, soleus wet weight was 28. 57% smaller and relative soleus weight was 28. 21% smaller in comparison with con-trol rats (p〈0.05) Soleus wet weight and relative soleus weight increased by 67.72% and 71.43% each with periodic weight support activity during hindlimb suspension (p〈0.01, p〈0.005), moreover soleus wet weight and relative soleus weight of the HS -WS rats were greater than those of the control group. No change was observed in fiber type percentage of the developing soleus muscle after 1 week of hindlimb suspension plus weight support activity. Type I and II fiber cross-sectional areas of the developing soleus muscle were 50.45% and 43.39% lower in the HS group than in the control group (p〈0.0001), type I and II fiber cross-sectional areas of the developing soleus were 24.49% and 29.93% greater in the HS - WS group than in the HS rats (p〈0.0001), whereas Type I and II fiber cross-sectional areas of HS - WS group were less than those of the control group, The results suggest that periodic weight support activity can ameliorate developing soleus muscle atrophy induced by hindlimb suspension, even in type II fibers that would not have been expected to be recruited by this type of neuromuscular demand. Clinical experimental study is needed to deter-mine the effect of periodic weight bearing exercise on developing atrophied leg muscle based on these results.

• Structural Engineering and Mechanics
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• 제11권4호
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• pp.341-356
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• 2001

A new class of semi-active tuned mass dampers, named as "Ground Hook Tuned Mass Damper" (GHTMD) is introduced. This TMD uses a continuously variable semi-active damper (so called 'Ground-Hook') in order to achieve more reduction in the vibration level. The ground-hook dampers have been used in the auto-industry as a means of reducing the vibration of primary suspension systems in vehicles. This paper investigates the application of this damper as an element of a tuned damper for the vibration reduction of force-excited single degree of freedom (SDOF) models that can be representative of many structural systems. The optimum design parameters of GHTMDs are obtained based on the minimization of the steady-state displacement response of the main mass. The optimum design parameters which are evaluated in terms of non-dimensional values of the GHTMD are obtained for different mass ratios and main mass damping ratios. Using the frequency responses of the resulting systems, performance of the GHTMD is compared to that of equivalent passive TMD, and it is found that GHTMDs are more efficient. A design methodology to obtain the tuning parameters of GHTMD using the relationships developed in this paper is presented.

• 한국음향학회지
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• 제14권5호
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• pp.29-35
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• 1995

진동판 변위의 비선형적 운동에 의해 발생하는 스피커의 비선형왜곡은 음질을 열화시킨다. 이러한 비선형왜곡은 저주파 대역의 경우 주로 스피커의 지지부의 강성과 force factor의 비선형 특성에 의해 발생한다. 본 논문에서는 진동판 변위에 따라 변화하는 스피커의 비선형 강성과 비선형 force factor를 2차함수로 모델링하고 각각의 계수를 결정하는 방법에 대해 연구하였다. 진동판에 질량을 부가하여 동작점을 이동시키는 기계적인 방법을 사용하여 강성과 force factor 간의 커플링을 배제하였으며, 여러 동작점에서의 공진주파수를 측정함으로써 비선형 강성의 계수를 추출하였다. 비선형 force factor의 계수는 공진주파수에서 스피커에의 입력전압, 입력전류, 그리고 진동판 변위를 측정하여 얻은 그래프를 curve fitting 함으로써 구하였다.

• Wind and Structures
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• 제24권4호
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• pp.367-384
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• 2017

The Maanshan Bridge over Yangtze River in China is a new long-span suspension bridge with double main spans of $2{\times}1080m$ and a closed streamline cross-section of single box deck. The flutter and buffeting performances were investigated via wind tunnel tests of a full bridge aeroelastic model at a geometric scale of 1:211. The tests were conducted in both smooth wind and simulated boundary layer wind fields. Emphasis is placed on studying the interference effect of adjacent span via installing a wind deflector and a wind separating board to shelter one span of the bridge model from incoming flow. Issues related to effects of mid-tower stiffness and deck supporting conditions are also discussed. The testing results show that flutter critical wind velocities in smooth flow, with a wind deflector, are remarkably lower than those without. In turbulent wind, torsional and vertical standard deviations for the deck responses at midspan in testing cases without wind deflector are generally less than those at the midspan exposed to wind in testing cases with wind deflector, respectively. When double main spans are exposed to turbulent wind, the existence of either span is a mass damper to the other. Furthermore, both effects of mid-tower stiffness and deck supporting conditions at the middle tower on the flutter and buffeting performances of the Maanshan Bridge are unremarkable.

• Journal of Plant Biotechnology
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• 제50권
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• pp.76-81
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• 2023

As cultured plant cells can grow in high oxidative stress conditions, they form an excellent system to study antioxidant mechanisms and the mass production of antioxidants. Oxidative stress is a major cause of damage in plants exposed to various types of environmental stress, including heavy metals, such as cadmium (Cd). Heavy metal accumulation can interfere with many cell functions and plant growth. To evaluate the contribution of oxidative stress to Cd-induced toxicity, cultured sweetpotato (Ipomoea batatas) cells were treated with increasing concentrations of Cd (0, 10, 25, and 50 μM) and cultured further. Cell growth was significantly inhibited by 25 and 50 μM of Cd, and the total protein content increased with 50 μM of Cd. Additionally, the activity of peroxidase (POD) and ascorbate peroxidase (APX), antioxidant enzymes that remove hydrogen peroxide (a reactive oxygen species), increased in the cells after treatment with 50 μM of Cd. The expression analysis of POD, APX, and peroxiredoxin (PRX) isolated from sweetpotato cultured cells in a previous study revealed the differential expression of POD in response to Cd. In this study, the expression levels of several acidic POD (swpa2, swpa3, and swpa4) and basal POD (swpb1, swpb2, and swpb3) genes were increased in Cd-treated cultured cells. These results indicate that Cd-mediated oxidative stress is closely linked to improved POD-mediated antioxidant defense capacity in sweetpotato suspension-cultured cells.

• Journal of Plant Biotechnology
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• 제4권1호
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• pp.23-27
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• 2002

To establish an in vitro mass production system of grape anthocyanin pigments through callus and cell suspension culture, the effects of nitrogen source and sucrose on fresh weight and anthocyanin production in cell suspension culture of 'Sheridan' grape level were studied. When the medium was devoid of $NO_3^-$, cell fresh weight was either remained stable (1% sucrose) or slightly decreased with culture time (2,3, and 4% sucrose). When $NH_4^-$ was lacking, 3% sucrose was most favorable for cell growth. When $NH_4^-$ was supplied as N source, the anthocyanin content of 2% sucrose containing medium was maintained 2 times higher than other levels till day 8 in culture, then that of 3 and 4% sucrose which peaked at day 12 thereafter. The anthocyanin content was low than $NO_3^-$-free media. Total anthocyanin content in $NH_4^-$-free medium was just about a half of that of $NH_4^+$ medium. Anthocyanin production of 2% sucrose in $NH_4^+$ medium was maintained about 3-fold till day 8, then decreased thereafter. In $NH_4^+$ medium, pH decreased gradually with final pH of 3.5 to 4.0, while pH in $NH_4^+$-free medium increased with final pH of 6.5 to 7.5.

• 오토저널
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• 제4권1호
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• pp.40-45
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• 1982

The spring constant and damping coefficient are vital factors of ride comfort and driving stability in the vibration of the vehicle which is mainly induced by a variety of the surface irregularity. This paper reviewed the optimum condition of the damping factor derived from the typical model of two mass-two degrees of freedom. Through the evaluation and discussion, it was presented that the spring of the torsion bar type was not effective for the driving stability in the large displacement of the wheel, and also that the damper with progressive performance has to be fundamentally selected to meet the requirement of the driving suability when this kind of spring is used as a suspension system of the vehicle.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2004년도 추계학술대회 논문집
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• pp.417-422
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• 2004

The vibration of a running vehicle can be classified on lateral, longitudinal and vertical motions. The important factor on the stability and ride quality of a railway vehicle is the lateral motion. The contact between wheel and rail with conicity influences strongly on the lateral motion. In this study, an experiment for the vibration of a running railway vehicle was performed using a small scale railway vehicle model. Also, the effects on the car body, bogie and wheelset were examined for the weight and the stiffness of the first and second suspension. The experimental results showed that the lateral vibration increases as the wheel conicity and stiffness of the second suspension increase. And the lateral vibration of the bogie increases as the mass ratio between car body and bogie increases. Also, the lateral vibration of the wheel becomes high at low speed, while the wheel of 1/20 conicity makes severe vibration at high speed running.

• 한국정밀공학회지
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• 제13권5호
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• pp.30-37
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• 1996

The objective of this research is to explore the analysis and test method for the reliable design and fabrication of a high precision dynamically tuned gyroscope. The tuning frequency is decided by the calculation of mass moment of inertia of rotor and gimbal and the stiffness of flexures. Due to the complex geometry of the flexure, calculation of the stiffness of the suspension flexure is difficult. In this paper, three analytical methods for obtaining the stiffness of the flexure are porposed and a special testing method is used for checking the accuracy of the computed results.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회A
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• pp.718-723
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• 2007

A three dimensional multibody modeling of a launcher system was developed and dynamic characteristics of the system was carried out. All the components were modeled as rigid bodies, All the components of system, ie; chassis, turret, cage and suspension parts, are modeled as rigid. The force interaction between the ground and tire was modeled as a point contact model. The factors were selected as cause and effect diagram of the MINITAB. To see effect of the stiffness, damping, mass at the launcher system, several cases of suspension parameters were compared and optimal values were selected. The stiffness and the damping coefficient were selected as design variables to minimize the required time for the next fire. The dynamic simulation was carried out using the ADAMS, and the MINITAB was employed for data analysis.