• Title/Summary/Keyword: mass fraction

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Association Between Low Muscle Mass and Non-alcoholic Fatty Liver Disease Diagnosed Using Ultrasonography, Magnetic Resonance Imaging Derived Proton Density Fat Fraction, and Comprehensive NAFLD Score in Korea

  • Lee, Hun Ju;Chang, Jae Seung;Ahn, Jhii Hyun;Kim, Moon Young;Park, Kyu-Sang;Ahn, Yeon-Soon;Koh, Sang Baek
    • Journal of Preventive Medicine and Public Health
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    • v.54 no.6
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    • pp.412-421
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    • 2021
  • Objectives: Non-alcoholic fatty liver disease (NAFLD) is an increasingly prevalent metabolic disease. Muscle is known to influence NAFLD development. Therefore, this study aimed to determine the relationships among low muscle mass, NAFLD, and hepatic fibrosis using various definitions of low muscle mass and NAFLD diagnostic methods, including magnetic resonance imaging-based proton density fat fraction (MRI-PDFF). Methods: This cross-sectional study included 320 participants (107 males, 213 females) from the Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population cohort. Muscle mass was assessed using whole-body dual-energy X-ray absorptiometry and adjusted for the height squared, body weight, and body mass index (BMI). NAFLD was diagnosed using ultrasonography (US), MRI-PDFF, and the comprehensive NAFLD score (CNS). Hepatic fibrosis was assessed using magnetic resonance elastography. Multivariable logistic and linear regression analyses were performed to determine the aforementioned associations. Results: According to US, 183 participants (57.2%) had NAFLD. Muscle mass adjusted for body weight was associated with NAFLD diagnosed using US (odds ratio [OR], 3.00; 95% confidence interval [CI], 1.70 to 5.31), MRI-PDFF (OR, 2.00; 95% CI, 1.13 to 3.53), and CNS (OR, 3.39; 95% CI, 1.73 to 6.65) and hepatic fibrosis (males: β=-0.070, p<0.01; females: β=-0.037, p<0.04). Muscle mass adjusted for BMI was associated with NAFLD diagnosed by US (OR, 1.71; 95% CI, 1.02 to 2.86) and CNS (OR, 1.95; 95% CI, 1.04 to 3.65), whereas muscle mass adjusted for height was not associated with NAFLD. Conclusions: Low muscle mass was associated with NAFLD and liver fibrosis; therefore, maintaining sufficient muscle mass is important to prevent NAFLD. A prospective study and additional consideration of muscle quality are needed to strengthen the findings regarding this association.

Chemical Composition of Fine Particulate Matter in the Downtown Area of Jeju City (제주시 도심지역 미세먼지의 화학적 조성 특성)

  • Hu, Chul-Goo;Lee, Ki-Ho
    • Journal of Environmental Science International
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    • v.27 no.7
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    • pp.597-610
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    • 2018
  • This study observed particulate matter ($PM_{2.5}$ and $PM_{10}$) in the downtown area of Jeju City, South Korea, to understand the chemical composition of particulates based on an analysis of the water-soluble ionic species contained in the particles. The mass fraction of the ionic species in the sampled $PM_{10}$ and $PM_{2.5}$ was 44.3% and 42.2%, respectively. In contrast, in Daegu City and Suwon City, the mass fraction of the ionic species in $PM_{2.5}$ was higher than that in $PM_{10}$. The chloride depletion percentage of $PM_{10}$ and $PM_{2.5}$ in Jeju City was higher than 61% and 66%, respectively. The contribution of sea-salt to the mass of $PM_{10}$ (5.9%) and $PM_{2.5}$ (2.6%) in Jeju City was similar to that in several coastal regions of South Korea. The mass ratio of $Cl^-$ to $Na^+$ in the downtown area of Jeju City was comparable to that in some coastal regions, such as the Gosan Area of Jeju Island, Deokjeok Island, and Taean City. The mass fraction of sea-salt in $PM_{10}$ and $PM_{2.5}$ was very low, and the concentration of sodium and chloride ions in $PM_{10}$ was not correlated with those in $PM_{2.5}$ ($R^2$ < 0.2), suggesting that the effects of sea-salt on the formation of particulate matter in Jeju City might be insignificant. The relationship between $NH_4{^+}$ and several anions such as $SO_4{^{2-}}$, $NO_3{^-}$, and $Cl^-$, as well as the relationship between the measurement and calculation of ammonium ion concentration, suggested that sea-salts may not react with $H_2SO_4$, and $(NH_4)_2SO_4$ may be a major secondary inorganic aerosol component of $PM_{2.5}$ and $PM_{10}$ in Jeju City.

A Study on Control of Dusts in Work Environment (유해 분진사업장의 분진제어에 관한 연구)

  • 김영식;오광중
    • Journal of Environmental Health Sciences
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    • v.21 no.2
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    • pp.1-6
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    • 1995
  • Authors investigated the size distribution and mass fraction of dusts in work environment of Changwon industrial complex. Size distribution of suspended dusts in welding and grinding processes were evaluated using ambient cascade impactors. The mass median diameters of dusts were 0.25 to $0.60 \mu m$ at welding sites and 1.20 to $1.92 \mu m$ at grinding sites. Respirable mass fractions were 63.68 to 73.50% at welding sites and 43.24 to 51.47% at grinding sites. Respirable fractions were calculated from the size distribution data for the ACGIH criteria by the respirable particle mass. In case of dust removal system, electrostatic precipitator and bag filter were appropriate for welding process and grinding process, respectively.

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Effect of Solid Mass Inventory on Hydrodynamics Characteristics in a Circulating Fluidized Bed (순환유동층에서 유동매체량에 따른 수력학적 특성 연구)

  • Kim, E.K.;Shin, D.;Lee, J.;Kim, J.;Hwang, J.
    • Journal of the Korean Society of Combustion
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    • v.7 no.4
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    • pp.10-20
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    • 2002
  • This paper discusses effect of solid mass inventory on the hydrodynamic characteristics of circulating fluidized bed(CFB). Operating parameters of solid mass inventory and air flow rates were varied to understand their effects on fludization pattern. Experimental measurements were made in a CFB of which height and diameter are 3m and 0.05m respectively. Black SiC particles ranging from $100{\mu}m\;to\;500{\mu}m$ were employed as the bed material. Superficial gas velocity of riser and J-valve fluidizing velocity were in the ranges of $1.39{\sim}3.24m/s\;and\;0.139{\sim}0.232m/s$, respectively. The axial solid fraction and solid circulation rate of CFB were calculated based on the experimental data and compared with modellings through IEA-CFBC Model and commercial CFD code.

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Performance of Flow Rate Control of a Cavitating Venturi (캐비테이션 벤튜리의 유량제어 성능)

  • Cho Won Kook;Moon Yoon Wan;Kim Young-Mog
    • 한국전산유체공학회:학술대회논문집
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    • 2002.05a
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    • pp.146-151
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    • 2002
  • Characteristics of flow rate control has been studied for a cavitating venturi adopted in a liquid rocket propellant feed system. Numerical simulation has been peformed to give about $10\%$ discrepancy of mass flow rate to the experimental data for cavitating flow regime. Mass flow rate is confirmed to be saturated for pressure difference higher than $3\times10^5$pa when the upstream pressure is fixed to $22.8\times10^5$pa and the downstream pressure is varied. The evaporation amount depends substantially to non-condensable gas concentration. However the mass flow rate characteristic is relatively insensitive to the mass fraction of non-condensable gas. So it is reduced by only $2\%$ when the non- condensable gas concentration is increased from 1.5PPM to 150PPM. From the previous comparison the expansions of the non-condensable gas and the evaporation of liquid are verified to have same effect to pressure recovery.

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HI gas kinematics of galaxy pairs in the Hydra cluster from ASKAP pilot observations

  • Kim, Shin-Jeong;Oh, Se-Heon
    • The Bulletin of The Korean Astronomical Society
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    • v.45 no.1
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    • pp.61.1-61.1
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    • 2020
  • We examine the HI gas kinematics and distribution of galaxy pairs in group or cluster environment from high-resolution Australian Square Kilometre Array Pathfinder (ASKAP) WALLABY pilot observations. We use 22 well-resolved galaxies in the Hydra cluster of which 4 galaxies are visually identified as pairs and others are isolated ones. We perform profile decomposition of HI velocity profiles of the galaxies using a new tool, BAYGAUD which enables us to separate a line-of-sight velocity profile into an optimal number of Gaussian components based on Bayesian MCMC techniques. All the HI velocity profiles of the galaxies are decomposed into kinematically cold or warm gas components with their velocity dispersion, 4~8 km/s or > 8 km/s, respectively. We derive the mass fraction of the kinematically cold gas with respect to the total HI gas mass, f = log10(M_cold / M_HI), of the galaxies and correlate them with their dynamical mass. The cold gas reservoir of the paired galaxies in the Hydra cluster is found to be relatively higher than that of the isolated ones which show a negative correlation with the dynamical mass in general.

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Separating of Falcarinol from Acanthopanax senticosus (가시오가피(Acanthopanax senticosus)에서 polyacetylene계 화합물인 falcarinol의 동정)

  • Kim, Seong-Ju;Chang, Kyu-Seob
    • Korean Journal of Food Science and Technology
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    • v.37 no.3
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    • pp.360-363
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    • 2005
  • To detect falcarinol in Acanthopanax senticosus, its stem and bark were extracted with methanol fractionated with petroleum ether and diethyl ether, and separated by silica gel column chromatography, Resulting six crude samples were compared with standard falcarinol through TLC on silica gel plates. Fraction 6 showed $R_{f}$ value of 0.46 similar to that of standard falcarinol. Through analytical reverse phase HPLC/PDA, UV spectra of standard falcarinol and traction 6 recorded between 200 and 340 nm showed identical peaks and UV spectra patterns. GC/MS revealed standard falcarinol and fraction 6 have equal retention times of 7.4 and 8.5 min before and after TMS-derivatization, respectively. Standard falcarinol and fraction 6 showed more similar spectrum patterns after TMS-derivatization than before. These results confirm presence of falcarinol in A. senticosus.

Chemopreventive Potential of an Ethyl Acetate Fraction from Curcuma Longa is Associated with Upregulation of p57kip2 and Rad9 in the PC-3M Prostate Cancer Cell Line

  • Rao, K.V.K.;Samikkannu, T.;Dakshayani, K.B.;Zhang, X.;Sathaye, S.S.;Indap, M.A.;Nair, Madhavan P.N.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.3
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    • pp.1031-1038
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    • 2012
  • Background: Turmeric ($Curcuma$ $longa$) has been shown to possess anti-inflammatory, antioxidant and antitumor properties. However, despite the progress in research with $C.$ $longa$, there is still a big lacuna in the information on the active principles and their molecular targets. More particularly very little is known about the role of cell cycle genes $p57^{kip2}$ and Rad9 during chemoprevention by turmeric and its derivatives especially in prostate cancer cell lines. Methods: Accordingly, in this study, we have examined the antitumor effect of several extracts of $C.$ $longa$ rhizomes by successive fractionation in clonogenic assays using highly metastatic PC-3M prostate cancer cell line. Results: A mixture of isopropyl alcohol: acetone: water: chloroform: and methanol extract of $C.$ $longa$ showed significant bioactivity. Further partition of this extract showed that bioactivity resides in the dichloromethane soluble fraction. Column chromatography of this fraction showed presence of biological activity only in ethyl acetate eluted fraction. HPLC, UV-Vis and Mass spectra studies showed presence three curcuminoids in this fraction besides few unidentified components. Conclusions: From these observations it was concluded that the ethyl acetate fraction showed not only inhibition of colony forming ability of PC-3M cells but also up-regulated cell cycle genes $p57^{kip2}$ and Rad9 and further reduced the migration and invasive ability of prostate cancer cells.

3D Numerical Study of Horizontal Falling Film Evaporator in Multi Effect Distillation (MED) Plant (MED 담수기내 수평관 강하막식 증발기의 3D 수치해석적 연구)

  • Kim, Soo Jae;Je, Junho;Kim, Moo Hwan
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.5
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    • pp.513-522
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    • 2013
  • In the present work, a numerical study of a horizontal falling film evaporator in a multi-effect distillation (MED) plant is performed. Tube bundles in the evaporator are described as porous media, and a volume-averaged method is applied. To calculate the fluid flow and phase change in the evaporator due to heat transfer in the system, FLUENT and user-defined functions (UDF) are used. To observe the performance of the evaporator under different operational conditions, tests are conducted for a steam mass flux ranging from 0.5 to 2.5 $kg/m^2s$ in the horizontal tube, for mass fraction of the noncondensable gas in the tube inlet ranging from 0% to 1%, and for film Reynolds numbers ranging from 100 to 1,000 for the falling film. The evaporation rate increases with the steam mass flux and Reynolds number. In contrast, the evaporation rate decreases by 0.87% with a 1% increase in the mass fraction of the noncondensable gas in the tube.

An Experimental Study on the Combustion Characteristics of CWM Single Droplet (CWM 단일액적의 연소특성에 관한 연구)

  • Park, Chong-Sang;Lee, Tae-Won;HA, Jong-Yul;Chung, Sung-Sik
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.24 no.3
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    • pp.402-410
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    • 2000
  • As the combustion process of CWM consists of the water evaporation, the release and combustion of volatile matter, and the combustion of char for every particle, it is more complex than that of existent liquid fuel. Though the many studies on CWM combustion have been carried out by the single droplet using hanging methods or the multiple droplet using atomization methods, any report don't presents definite solution about the effects by the initial water evaporation and combustion of volatile. When CWM is suddenly exposed in the high temperature surroundings, the internal water evaporates and then each droplet builds up pores. Besides, porosity rate changes along the temperature of surroundings, the composition ratio of CWM, and the initial diameter of droplet. In result, because it affects the whole combustion rate, the combustion of CWM has complex mechanism as compared with the combustion of liquid or gas fuel. Therefore, concentrating on porous structure of CWM, this study has proceeded to acquire the basic data on the CWM injection combustion and closely examines the effects of the first stage combustion on the whole combustion by measuring the diameter variations, pore rate, mass fraction burned, and the internal temperature changes of CWM droplet. The results demonstrate that $60{\sim}70%$ of initial mass is reduced during water evaporation and volatile combustion period, and swelling rate, mass faction burned, and density variation are greatly concerned with atomization of CWM etc.