• Herbal Formula Science
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• v.20 no.2
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• pp.165-176
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• 2012

In pathologically analyzing, 'Qi(氣)' is fall downed 'Zheng-Qi(正氣; Base energy of human body)' or 'Wai-Gan-Xie-Qi(外感邪氣; poisoned energy from outside of human body)'. And all extroverted symptoms from this 'Qi(氣)' is 'Shang-Chong(上衝)'. Also this symptom's basic mechanism is deficiency of 'Zhong-yang(中陽; basic active energy acting pivot)' by non-proper 'Xia-fa(下法; treatment way getting out focus to down side)' at early days of 'Tai-Yang-bing (太陽病; Primary stage symptoms when the cold energy of the outside tresspasses the external layer of body)'. And comparing herbs in medicines for treating 'Shang-Chong(上衝)' in Shang han lun with Japanese in Shang-han medical practitioner's view, there is 'Ping-Chong(平衝; Supress out bursting energy)''s effect when use 'Gui-zhi(桂枝; Cinnamomum cassia loureirii zeylanuicum)' for mass dosage. Based on these, 'Qi-Shang-Chong(氣上衝)' means all of the symptom's aspects which called 'Yang(陽)''s aspect that is extrovesity, dynamic and imminent by results of the experiment about Cinnamaldehyde which are the main ingredients of 'Gui-zhi(桂枝; Cinnamomum cassia loureirii zeylanuicum)' and clinical data of 'Gui-zhi-tang(桂枝湯)'.

• Herbal Formula Science
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• v.9 no.1
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• pp.137-163
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• 2001

From ancient times to Ching Dynasty, we studied the causes and oriental prescriptions of purpura for 23 oriental medical records. The results were obtained as follows ; 1. Purpura is a disease that raises the purplish speckle or speckle mass on the skin by blood overflowing between flesh and skin and belongs to speckle occurrence(Balban, 發斑) or blood symptom(Hyeoljeong, 血證). 2. At ancient times, purpura named Balban(發斑), Banjin(斑疹), Yin-yang dok(陰陽毒), Podoyeok(葡萄疫) and Bansa etc. 3. In oriental carse of purpura, Insufficient symptoms are gastric energy insufficiency and groundless frame, and Sufficient symptoms are heat-evil in stomach, blood heat, season's improper energy, yin-evil height and wind-heat with phlegm. 4. At oriental prescriptions on purpura, Insufficient symptom used Hwabantang(化斑湯) mostly, the next Hyunsam-seugmatang(玄蔘升麻湯), Jojungtang(調中湯), Seogakcheongdaeeum(犀角靑黛飮), Heuknowhan(黑奴丸) and Sufficient symptom used Jojungikgitang(調中益氣湯), Wibitang(胃脾湯), Daegeonjungtang(大建中湯), Hwanggi-geonjungtang etc. much. 5. The medicines for external use for purpura were Mil(蜜), Seungma(升麻t), Mangcho-jeodamjeup(芒硝猪膽汁), Geongal(乾葛), Seontae(蟬退), Chongbaek and Gangjeup(薑汁) etc., pregnant woman used jeongjeoni(井底泥). 6. The order of medicines were Seungma(升麻), Hwanggi, Insam(人蔘), Seokgo(石膏), Seogak(犀角), Hyunsam(玄蔘) and Chija(梔子) ect.

• Korean Journal of Clinical Laboratory Science
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• v.37 no.3
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• pp.207-211
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• 2005

Body index is known as it affects pulmonary function tests (PFT), so it has been used with predictive formula and nomogram in terms of sex, age, height, etc. Body indices as body weight, body mass index (BMI), and body surface area (BSA) might also affect PFT, so that we have analyzed the correlations between body indices and forced expiratory volume in one second ($FEV_1$), and have done multiple regression analysis to see how body indices affect $FEV_1$. We confirmed that $FEV_1$ had positive correlations with height (r=0.49, p<0.01), body weight (r=0.37, p<0.01), and BSA (r=0.47, p<0.01), inverse correlation with age (r=-0.45, p<0.01), but no correlation with BMI. We found that the 41.9% of $FEV_1$ was diverged from height, age and BSA. Therefore, BSA definitely needs to be considered with predictive formula and nomogram in PFT.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.10
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• pp.4943-4952
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• 2013

This study was conducted among Korean women over aged 60 who participated in Korea National Health and Nutrition Examination Survey (KNHANES) (the 2nd and 3rd year at the 4th survey, and the 1st year at the 5th survey). The purpose of the study was to figure out a relation between femoral neck and lumbar spine bone mineral density and anthropometry, life style, diet, fracture history, family history of osteoporosis, medical history, menstrual history and reproductive factor. To express the strength of the associations, percent differences were calculated from multiple linear regression models using the formula ${\beta}{\times}$(unit/mean BMD). Unit for continuous variables were chosen to approximate 1 standard deviation(SD). In women aged 60 or older, lean mass(B: 0.257) and fat mass(B: 0.237) greatly influenced bone density in the femoral neck and lumbar spine. Therefore it will be an effective way to prevent osteoporosis for elderly women by increasing lean mass and maintaining proper weight.

• Food Science of Animal Resources
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• v.35 no.4
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• pp.466-472
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• 2015

A rapid and simple analytical method, using liquid chromatography tandem mass spectrometry (LC-MS/MS), was developed to detect myo-inositol (MI) in infant formulas. For protein removal: acid hydrolysis and lipid removal through organic solvent extraction. The operating conditions for instrumental analysis were determined based on previously reported analogous methods that used LC-MS/MS. Quantitative analysis was used for the detection limit test, infant formula recovery test, and standard reference material (SRM) 1849a to verify the validity of our LC-MS/MS analytical method, which was developed to quantify MI. For validation, the results of our method were compared with the results of quantitative analyses of certified values. The test results showed that the limit of detection was 0.05 mg/L, the limit of quantitation was 0.17 mg/L, and the method detection limit was 17 mg/kg. The recovery test exhibited a recovery between 98.07-98.43% and a relative standard deviation between 1.93-2.74%. Therefore, the result values were good. Additionally, SRM 1849a was measured to have an MI content of 401.84 mg/kg and recovery of 98.25%, which is comparable to the median certified value of 409 mg/kg. From the aforementioned results, we judged that the instrumental analysis conditions and preparation method used in this study were valid. The rapid analytical method developed herein could be implemented in many laboratories that seek to save time and labor.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.18 no.5
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• pp.29-36
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• 2019

In modern society in which the fourth industrial revolution has come to the fore and rapid technology innovations are taking place, a phenomenon of making and selling small quantities of various products that consumers want instead of mass producing one item has emerged. As the market is moving toward the multi-item small-sized production system, there is a need for a system in which a machine independently judges and carries out machining and post-processing. In order for a machine to judge processing on its own, it is necessary to measure the force applied to a product. This study aimed to develop a large-scale dynamometer that enables three-axis measurement using octagonal ring load cells. As for the device's configuration, four octagonal ring load cells, which were previously researched, were used to enable three-axis measurement. It was reconfigured by modifying the attachment position of the octagonal ring load cells' strain gauge and the Wheatstone bridge of each axis, and a system was set up to allow the monitoring of data measured through the monitor. The configured device calculated a strain rate by an experiment, and this rate was compared with the theoretical strain rate to find a correction value. The correction value was entered into a formula, deriving a modified formula. The modified formula was entered into the device, which completed the large-scale dynamometer.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.26 no.2
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• pp.99-115
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• 2023

Purpose: Exclusive breastfeeding promotes gut microbial compositions associated with lower rates of metabolic and autoimmune diseases. Its cessation is implicated in increased microbiome-metabolome discordance, suggesting a vulnerability to dietary changes. Formula supplementation is common within our low-income, ethnic-minority community. We studied exclusively breastfed (EBF) neonates' early microbiome-metabolome coupling in efforts to build foundational knowledge needed to target this inequality. Methods: Maternal surveys and stool samples from seven EBF neonates at first transitional stool (0-24 hours), discharge (30-48 hours), and at first appointment (days 3-5) were collected. Survey included demographics, feeding method, medications, medical history and tobacco and alcohol use. Stool samples were processed for 16S rRNA gene sequencing and lipid analysis by gas chromatography-mass spectrometry. Alpha and beta diversity analyses and Procrustes randomization for associations were carried out. Results: Firmicutes, Proteobacteria, Bacteroidetes and Actinobacteria were the most abundant taxa. Variation in microbiome composition was greater between individuals than within (p=0.001). Palmitic, oleic, stearic, and linoleic acids were the most abundant lipids. Variation in lipid composition was greater between individuals than within (p=0.040). Multivariate composition of the metabolome, but not microbiome, correlated with time (p=0.030). Total lipids, saturated lipids, and unsaturated lipids concentrations increased over time (p=0.012, p=0.008, p=0.023). Alpha diversity did not correlate with time (p=0.403). Microbiome composition was not associated with each samples' metabolome (p=0.450). Conclusion: Neonate gut microbiomes were unique to each neonate; respective metabolome profiles demonstrated generalizable temporal developments. The overall variability suggests potential interplay between influences including maternal breastmilk composition, amount consumed and living environment.

• Journal of the Korean Home Economics Association
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• v.37 no.7
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• pp.17-27
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• 1999

According to the design method for constructing the Korean Men's Jo-go-ri(the traditional Korean jacket)collar, there are differences in form after its completion. In the construction design of the midsection of the gusset as in that of the basic pattern Jo-go-ri, not only was the positioning of the two sides of the collar not smooth, but also, when the collar strip(Dongjung) was attached, there would be an imbalance on one side or the other so that it was difficult to achieve symmetry. Therefore in this project, by applying the pattern design of the gusset midsection to that of the collar midsection, not only did attaching the collar(Kit) and the collar strip create a visual effect by equalizing the lengths of the two sides, but the construction was also easy. This method of construction introduces the three-dimensional aspect of the human form in its conic, spherical and cylindrical aspects, so that, through schematizing the scientific character of Korea's clothing, its appropriateness is verified. As a matter of fact, since there is no standardization of pattern whether for educational use or for mass-produced clothing, so that even the patterns used in computer-assisted design are executed according to the designer's personal skill, the reality is that after completion of construction the quality has not been uniform. For this schematization, inverse calculation of measurements pertaining to the calculation formula and of teaching materials has been referenced. In particular, the partial regulation of the calculation formula pertaining to the basic pattern construction, the method of making the collar midsection, and the construction method of the extreme and mean ratio adjustment, can be adjusted for all measurements, thereby providing the establishment of a design criterion and the possibility of the standardization of construction methods. The production method for the basic pattern design is as follows: 1) The conic angle for the Jo-go-ri's girth, length end neck width is fixed at 70(72) degree. 2) The radius of the cone is sleeve length. 3) The bust girth calculation formula is B/4 + 2.5 cm. 4) The armhole formula is B/4 + 2.5cm. 5) The neck width formula is B/10. 6) The ratio of the collar junction{width of collar(Kit) + width of collar strip(Dongjung) to the gusset length is 5:8. 7) The length of the side seam is a length intersecting the armhole line and the conic radius of sleeve length, that is an arc that exceeds the length of the Jo-go-ri's midsection.

• Journal of Nutrition and Health
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• v.30 no.2
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• pp.155-169
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• 1997

This study investigated the effect of weight control by using the commercial appetite suppressant ((-)-hydroxycitric acid(HCA) formula) and nutrition education on 72 obese women over a period of 8 weeks. During the study it conducted nutritional education for women to control their weight, thus analyzed their changes in anthropometric variables. All obese women were randomized in a double-blind method to consume either HCA(HCA group : experimental group) or placebo(placebo group : control group). Two groups were also divided randomly into 2 groups combined with commercial formula diet in 1 meal a day(HD group and PD group : HCA + gormula diet and placebo + formula diet) or not(HO group and conducted with 4 groups(HD, HO, PD, and PO group). All subjects were assigned to consume 800-1500kcal/d balanced diet which is 500kcal less than their usual energy requirement. To evaluate the effect of the weight control program, weight, percent of body fat, waist and hip circumferences, and 5 skinfold thickness were measured up to 5 times in all obese women. The mean weight of the subjects at the onset of the study was 76.5$\pm$10.6kg. The mean body mass index(BMI) wa 30.1$\pm$3.8 and it was in the upper 5 percentile of mean BMI of Korean women. At the end of the program, mean weight loss was 3.5kg after 2 weeks(p<0.001), and 5.8kg after 4 weeks(p<0.001). The waist, hip ratio(WHR) and skinfold thickness measurements of biceps, triceps, subscapular, suprailiac and abdominum showed significant reduction over the entire study period(p<0.05). These outcome were evaluated by effect of nutritional education and counselling. The reduction of % of body fat was significantly different among the 4 groups. Women who administrated HCA demonstrated more change in weight, BMI than the placebo group. There was also significant reduction in body composition (% of body fat, WHR, and skinfold thickness) than the other groups. The HD group which was administrated HCA combined with formula diet was more decreased than other groups. It showed that this program using commercial HCA and formula diet induced not only a change in weight but also a change in body composition. The outcome of this study suggests that HCA has a more effctive change on weight control which is carried out with nutritional education and counselling.

• Journal of the Korean Geotechnical Society
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• v.38 no.10
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• pp.41-48
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• 2022

The mass density of the medium (ρ) used to calculate the maximum shear modulus (G_max) of the saturated ground based on the shear wave velocity is unclear. Therefore, to determine the mass density, a verification formula and five scenarios were established. Laboratory tests were conducted, and the obtained results were compared. The mass density of the medium was assumed to be saturated (ρ_sat), wet (ρ_t), dry (ρ_dry), and submerged conditions (ρ_sub), and the V_s ratios of saturated to dry condition were obtained from each case. Assuming the saturated density (ρ_sat), the V_s ratio was consistent with the value from the resonant column test (RCT) results, and the value from the bender element test results was consistent with the wet density assumption (ρ_t). Considering the frequency range of earthquakes, it is concluded that applying the saturated density (ρ_sat) is reasonable as in the RCT results.