• 한국전산유체공학회지
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• 제1권1호
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• pp.55-63
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• 1996

Numerical computations are carried out to analyze the characteristics of flow fields around Air Supported Ships. The computations are performed in a rectangular grid system based on MAC(Marker And Cell) method. The governing equations are represented in finite difference forms by forward differencing in time and centered differencing in space except for its convection terms. For the certification of this numerical analysis method, the computations of flow fields around a Catamaran, an ACV(Air Cushion Vehicle) modeled with pressure distribution on free surface and two SES(Surface Effect Ship)'s are carried out, The results of the present computations are compared with the previously presented computational and experimental results in the same condition.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 하계종합학술대회 논문집(3)
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• pp.199-202
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• 2002

We described a real-time 3D computer vision system called MIMIC(Motion interface f Motion information Capture system) that can capture and save motion of an actor. This system analyzes input images from vision sensors and searches feature information like a head, hands, and feet. Moreover, this estimates intermediated joints as an elbow and hee using feature information and makes 3D human model having 20 joints. This virtual human model mimics the motion of an actor in real-time. Therefore this system can realize the movement of an actor unaffectedly because of making intermediated joint for complete human body contrary to other marker-free motion capture system.

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2003년도 식물바이오벤처 페스티발
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• pp.107-107
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• 2003

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2005년도 추계학술대회 및 한일 식물생명공학 심포지엄
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• pp.440-440
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• 2005

• Journal of Korean Neurosurgical Society
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• 제59권1호
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• pp.44-51
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• 2016

Objective : Malignant gliomas with neuronal marker expression (MGwNM) are rare and poorly characterized. Increasingly diverse types of MGwNM have been described and these reported cases underscore the dilemmas in the classification and diagnosis of those tumors. The aim of this study is to provide additional insights into MGwNM and present the clinicopathological features of 18 patients. Methods : We reviewed the medical records of 18 patients diagnosed as MGwNM at our institute between January 2006 and December 2012. Macroscopic total resection was performed in 11 patients (61%). We evaluated the methylation status of $O^6$-methylguanine-DNA methyltransferase (MGMT) and expression of isocitrate dehydrogenase 1 (IDH-1) in all cases, and deletions of 1p and 19q in available cases. Results : The estimated median overall survival was 21.2 months. The median progression-free survival was 6.3 months. Six patients (33%) had MGMT methylation but IDH1 mutation was found in only one patient (6%). Gene analysis for 1p19q performed in nine patients revealed no deletion in six, 19q deletion only in two, and 1p deletion only in one. The extent of resection was significantly correlated with progression free survival on both univariate analysis and multivariate analysis (p=0.002 and p=0.013, respectively). Conclusion : In this study, the overall survival of MGwNM was not superior to glioblastoma. The extent of resection has a significant prognostic impact on progression-free survival. Further studies of the prognostic factors related to chemo-radio therapy, similar to studies with glioblastoma, are mandatory to improve survival.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2004년도 학술대회지
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• pp.90-95
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• 2004

During the past 50 years methods for predicting wave overtopping of coastal structures have coastal structures have continuously been developed Wave overtopping is one of the most important processes for the design of seawalls. The term 'wave overtopping' is used here to refer to the processes where waves hit a sloping structure run up the slope and, if the crest level of the slope is lower than the highest run up level, overtop the structure. Wave overtopping is dependent on the processes associated with breaking wave. The Numerical model is based on Navier-Stokes equation and Marker-Density Function of method for nonlinear free-surface flow by Miyata & Park(1995). The influence of how the slopes of seawalls, wave type and crest freeboard affect overtopping discharges has been investigated. The research of study using the new development nonlinear free-surface flow numerical model SOLA-VOF are presented.

• 대한조선학회논문집
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• 제51권5호
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• pp.419-428
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• 2014

This paper presents a numerical simulation method for the flow around advancing ships in regular waves by using a rectilinear grid system. Because the grid lines do not consist with body surface in the rectilinear grid system, the body geometries are defined by the interaction points of those grid lines and the body surface. For the satisfaction of body boundary conditions, no-slip and divergence free conditions are imposed on the body surface and body boundary cells, respectively. Meanwhile, free surface is defined with the modified marker density method. The pressure on the free surface is determined to make the pressure gradient terms of the governing equations continuous, and the velocity around the free surface is calculated with the pressure on the free surface. To validate the present numerical method, a vortex induced vibration (VIV) phenomenon and flows around an advancing Wigley III ship model in various regular waves are simulated, and the results are compared with existing and corresponding research data. Also, to check the applicability to practical ship model, flows around KRISO Container Ship (KCS) model advancing in calm water are numerically simulated. On the simulations, the trim and the sinkage are set free to compare the running attitude with some other experimental data. Moreover, flows around the KCS model in regular waves are also simulated.

• Journal of Mechanical Science and Technology
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• 제15권3호
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• pp.384-391
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• 2001

The aerodynamic effects of a 3-dimensional Wing in Ground Effect (WIG) which moves above the free surface has been numerically investigated via finite difference techniques. The air flow field around a WIG is analyzed by a Marker & Cell (MAC) based method, and the interactions between WIG and the free surface are studied by the pressure distributions on the free surface. Waves are generated by the surface pressure distribution, and a Navier-Stokes solver has been employed, to include the nonlinearities in the free surface conditions. The pressure values Cp and lift/drag ratio are reviewed by changing the height/chord ratio. In the present computations a NACA0012 airfoil with a span/chord ratio of 3.0 are treated. Through computational results, it is confirmed that the free surface can be treated as a rigid wavy wall.

• 생명과학회지
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• 제24권6호
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• pp.618-625
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• 2014

쌀가루는 많은 식품 가공에 이용된다. 그러나 밀가루 반죽이 빵과 면을 포함한 많은 식품 가공 제품에 적합한 반면에, 쌀로 만든 반죽은 신장성과 탄력성이 부족하다. 고분자 글루테닌 서브유닛(HMW-GS)은 밀의 가공 적성을 결정하는데 중요한 역할을 한다. 본 연구에서, 우리는 아그로박테리움(Agrobacterium) 동시 형질전환법을 이용하여 한국 밀 품종인 '조경'으로부터 HMW-GS를 암호화하는 밀 Glu-1Dy10 유전자를 발현하는 marker-free 형질전환 벼 식물체를 개발하였다. 오직 Glu-1Dy10 유전자와 HPTII (hygromycin phosphotransferase II) 저항성 유전자만을 포함하는 분리된 DNA 조각들로 구성된 두 가지 발현 카셋트(cassettes)를 독립적으로 아그로박테리움(Agrobacterium) EHA105 에 도입하였다. Glu-1Dy10 또는 HPTII를 함유하는 EHA105 를 각각 3:1 비율로 벼 캘러스에 접종하였다. 290개의 하이그로마이신(hygromycin) 저항성 $T_0$ 식물체 중에서 우리는 벼 게놈에 Glu-1Dy10과 HPTII 유전자가 모두 삽입된 29개의 형질전환 라인을 획득하였다. 우리는 Glu-1Dy10 유전자가 벼 게놈 내로 도입된 것을 Southern blot 분석을 통해 다시 확인하였다. 형질전환 벼 종자에서 Glu-1Dy10의 전사(Transcripts)와 단백질을 semi-quantitative RT-PCR과 Western blot 분석을 통해서 확인하였다. 최종적으로, 오직 Glu-1Dy10 유전자를 갖는 marker-free 식물체를 $T_1$ 세대에서 성공적으로 선발할 수 있었다.

• 생명과학회지
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• 제23권11호
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• pp.1317-1324
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• 2013

고분자 글루테닌 서버유닛(high molecular-weight glutenin subunit, HMW-GS)은 밀의 가공적성을 결정하는데 중요한 역할을 수행한다. 우리는 Agrobacterium 동시 형질전환법을 이용하여 한국 밀 품종인 '조경'으로부터 밀 HMW-GS을 암호화하는 Glu-1Bx7 유전자를 가지는 marker-free 형질전환 벼를 생산하였다. Glu-1Bx7 유전자의 종자 특이적 발현을 위하여 밀 Glu-1Bx7 유전자 자체 프로모터를 벡터 내에 삽입하였다. 동시 접종을 위해서 오직 Glu-1Bx7 유전자와 hygromycin phosphotransferase II (HPTII) 저항성 유전자만으로 구성된 두 종류의 발현 카셋트를 독립적으로 Agrobacterium EHA105에 도입하였고, Glu-1Bx7와 HPTII가 도입된 각각의 EHA105 Agrobacterium 을 3:1 비율로 혼합하여 벼 캘러스에 접종하였다. 216개의 HPTII 저항성 형질전환체 중에서 벼 게놈에 Glu-1Bx7과 HPTII가 모두 삽입된 24개의 형질전환 라인을 획득하였다. Glu-1Bx7와 HPTII가 벼 게놈에 도입된 것을 Southern blot을 통해서 다시 확인하였다. 형질전환 벼 $T_1$ 세대의 종자에서 밀 Glu-1Bx7 유전자가 전사와 번역되어 오직 Glu-1Bx7만을 가지는 marker-free 식물체를 $T_1$ 세대에서 성공적으로 선발할 수 있었다.