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Nitrous oxide splurge in a tertiary health care center and its environmental impact: No more laughing stock

  • Amit Sharma;GD Puri;Rajeev Chauhan;Ankur Luthra;Gauri Khurana;Amarjyoti Hazarika;Shyam Charan Meena
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.24 no.1
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    • pp.67-73
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    • 2024
  • Background: Nitrous oxide has been an integral part of surgical anesthesia for many years in the developed world and is still used in developing countries such as India. The other main concerns in low-resource countries are the lack of an advanced anesthesia gas-scavenging system and modular surgical theatres. As a greenhouse gas that has been present in the atmosphere for more than 100 years and damages the ozone layer, nitrous oxide is three times worse than sevoflurane. Here, we conducted an observational study to quantify the annual nitrous oxide consumption and its environmental impact in terms of carbon dioxide equivalence in one of busiest tertiary health care and research centers in Northern India. Methods: Data related to nitrous oxide expenditure' from the operation theatre and manifold complex of our tertiary care hospital and research center from 2018 to 2021 were collected monthly and analyzed. The outcomes were extracted from our observational study, which was approved by our institutional ethics board (INT/IEC/2017/1372 Dated 25.11.2017) and registered prospectively under the Central Registry (CTRI/2018/07/014745 Dated 05.07.2018). Results: The annual nitrous oxide consumption in our tertiary care hospital was 22,081.00, 22,904.00, 17,456.00, and 18,392.00 m3 (cubic meters) in 2018, 2019, 2020, and 2021, respectively. This indicates that the environmental impact of nitrous oxide (in terms of CO2 equivalents) from our hospital in 2018, 2019, 2020, and 2021 was 13,016.64, 13,287.82, 10,289.94, and 10,841.24 tons, respectively. Conclusion: This huge amount of nitrous oxide splurge is no longer a matter of laughter, and serious efforts should be made at every central and peripheral health center level to reduce it.

Evaluation of Long Term Operation of Cross-flow Molten Carbonate Fuel Cell Stack (교차류형 100W급 용융탄산염 연료전지 스택 장기운전평가)

  • Lim, H.C.;Seol, J.H.;Ryu, C.S.;Lee, C.W.;Hong, S.A.
    • Journal of Hydrogen and New Energy
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    • v.6 no.2
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    • pp.53-63
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    • 1995
  • A 100kW class stack consisting of 10 molten carbonate fuel cells has been fabricated. Internally manifold stack has been tested for endurance. Each cell in the stack had an electrode area of $100cm^2$ and reactant gases were distributed in each cells in a cross-flow configuration. Initial and long term operation performance of the stack was investgated as a function of gas utilization using a specially designed small scale stack test facility. It was possible to have a stack with an output of more than 100W using an anode gas of 72% $H_2/18%$ $CO_2/10%H_2O$ and cathode gas of 33% $O_2/67%$ $CO_2$ and 70% Air 30% $CO_2$. The output and voltage of the stack at a current 15A($150mA/cm^2$) and gas utilization of 0.4 showed 125.8W and 8.39V respectively by elapsed time of 310 hours operation. In long term operation characteristics, the voltage drop of 52.4mV/1000hour was observed after more than 1,840 hours operation. Among the voltage drop, the OCV loss was highest than other voltage loss such as internal resistance and electrode polarization. Non uniformity of 2voltages and degradation of cell voltage in the stack was observed in according to changing the utilization rate after a long term operation. Further work for increasing the performance prolonging the life of the stack are required.

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R&D Funding and R&D Performance : The Moderating Effect of Indirect R&D Cost Ratio (연구비 재원과 연구개발성과 : 간접비 비율의 조절효과를 중심으로)

  • Lee, Joonbeom
    • Journal of Korea Technology Innovation Society
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    • v.21 no.1
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    • pp.420-453
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    • 2018
  • In the growth of the government's investment in national R&D project and the abuse of research expense, an effective control and management mechanism is strongly demanded. However, an excessive regulation might hinder the R&D performance, which also endangers the underlying objective of R&D policy. Especially, an excessive regulation on the R&D expenditure may damage the SMEs (Small and Medium sized Enterprises) where securing an adequate level of R&D funding is vital. This study investigates the R&D funding and R&D performance of SMEs participating in the national R&D project by using fixed effect panel model. As a result, this paper reveals the effectiveness of 'Government R&D subsidy'. However, that of 'private R&D fund' is not supported strongly. Also, this paper empirically demonstrates the efficiency of both 'Government R&D subsidy' and 'Private R&D fund' as the R&D costs are spent discretionarily (as the degree of 'Indirect Cost Ratio' increases). Especially, the effectiveness of 'Private R&D fund' can be moderated by 'Indirect Cost Ratio'. On the basis of the conclusions, this paper draws an implication that can increase R&D performance of SMEs through the interactions of manifold administrative values (i.e. effectiveness, efficiency and responsibility).

Analysis on Volumetric Efficiency and Torque Characteristics Using Inlet Port Pressure in SI Engines (흡기포트압력을 이용한 SI엔진의 체적효율 및 토크 성능 분석)

  • 이영주;홍성준
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.16 no.7
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    • pp.1408-1418
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    • 1992
  • The valve timing and intake system in SI engine is chosen in order to get the maximum performance at the target rpm. This is a compromise and the performance reduction is expected in a certain rpm range. Therefore, to accomplish the possible engine capacity all over the operation ranges, it is required to investigate the effects of intake system and valve timing on engines more thoroughly. In this paper, it was attempted to examine closely the combined effects on the torque and the volumetric efficiency due to the change of valve timing and intake system dimensions. For this, the inlet port pressure was chosen as a primary parameter to represent engine performance characteristics together with surge tank pressure and induction pressure as secondaries. The inlet port pressure was analyzed in connection with both the secondaries and the performance data. Especially the relation between the inlet port pressure and the torque and volumetric efficiency was investigated on the operating conditions. In this experiment, it was acquired that the performances at specific rpm range could be improved by the combinations of valve timing and intake system. Then it was verified that pressure at a intake system contained useful data for the engine performance. By the analysis of inlet port pressure with the others, it was obtained that the properties of the torque and the volumetric efficiency due to the change of valve timing and intake conditions were able to be defined by the average and the maximum inlet port pressures, the pressure near before the intake valve closing(IVC) point as well as the pressure at IVC point during the intake valve opening duration. These results could be applied to almost all over the experimental conditions.

Spherical-Coordinate-Based Guiding System for Automatic 3D Shape Scanning (3D 형상정보 자동 수집을 위한 구면좌표계식 스캐닝 시스템)

  • Park, Sang Wook;Maeng, Hee-Young;Lee, Myoung Sang;Kwon, Kil Sun;Na, Mi-Sun
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.38 no.9
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    • pp.1029-1036
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    • 2014
  • Several types of automatic 3D scanners are available for use in the 3D scanning industry, e.g., an automatic 3D scanner that uses a robot arm and one that uses an automatic rotary table. Specifically, these scanners are used to obtain a 3D shape using automatic assisting devices. Most of these scanners are required to perform numerous operations, such as merging, aligning, trimming, and filling holes. We are interested in developing an automatic 3D shape collection device using a spherical-coordinate-based guiding system. Then, the aim of the present study is to design an automatic guiding system that can automatically collect 3D shape data. We develop a 3D model of this system and measuring data which are collected by a personal computer. An optimal design of this system and the geometrical accuracy of the measured data are both evaluated using 3D modeling software. The developed system is then applied to an object having a highly complex shape and manifold sections. Our simulation results demonstrate that the developed system collects higher-quality 3D data than the conventional method.

A Study for Failure Examples of Emission Gas Recirculation and Air Control and Catalyzed Particulate Filter System in Diesel Engine Vehicle (디젤엔진 자동차의 EGR 및 공기 제어와 CPF 장치에 관련된 고장사례 고찰)

  • Lee, IL Kwon;Kook, Chang Ho;Ham, Sung Hoon;Lee, Young Suk;Youm, Kwang Wook;You, Chang Bae;Kim, Sung Mo;Lim, Ha Young;Ahn, Ho Cheol;Lee, Jeong Ho
    • Journal of the Korean Institute of Gas
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    • v.22 no.2
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    • pp.78-83
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    • 2018
  • The purpose of this paper is to study for failure examples of emission gas recirculation and air control and catalyzed particulate filter system in diesel engine vehicle. The first example, the researcher found the fact that the much engine oil came into the intake manifold causing diaphragm damage of EGR valve. The engine oil entered into combustion chamber of engine so that a car emit the polluted exhaust gas when driving. The second example, the researcher certified the sticking phenomenon of carbon and foreign substance with the throttle flap so that the exhaust fumes discharged exhaust port. The third example, the regeneration function don't activated to not detect the temperature of exhaust gas because of damage in the sensor. Thus, the researcher must meticulously manage his car not in order to take place the problem of environmental pollution.

A Study on the FIDIC Conditions of Contract for Design, Build and Operate Projects (FIDIC의 DBO 프로젝트용 표준계약조건에 관한 연구)

  • Choi, Myung-Kook
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.46
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    • pp.29-60
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    • 2010
  • The incentive and reasons to publish FIDIC Conditions of Contract for Design, Build and Operate Projects(DBO Form) are manifold. It is partly a response to the increasing need for sophisticated project delivery methods in both the public and private sectors and the already widespread use of the FIDIC Yellow Book with operation and maintenance obligations and partly a response to the challenge to decrease maintenance cost to a minimum by means of a new procurement route. As a result, FIDIC has developed a new model form to meet this market place requirement. On the other hand, FIDIC did not simply adapt the Yellow Book but has developed a new form from it, whilst preserving the style of the already known FIDIC Forms and maintaining the wording where it was not necessary to change it for the purposes of a DBO Form. Moreover DBO Form fills up supposed gaps in other FIDIC Forms and ameliorates the claim management and dispute management framework. FIDIC DBO approach may be shortly summarized as follows. First, DBO Form provides for single project responsibility. Second, DBO Form has the clear objective of ensuring the use of a most reliable and efficient technology at the lowest life-cycle cost. Third, DBO Form is intended to operate as an effective quality increase in the design and construction of projects. Fourth, DBO Form is intended to provide significant benefits with regard to system integration and reduction of risks. Fifth, DBO Form accelerates and enhances completion schedule compliance. Sixth, DBO takes care of all three supporting pillars of sustainability(including economical, environmental and social elements). DBO Form is obviously a good starting point for negotiations and the preparation of calls for tenders, thus saving the parties time and money. However, existing cultural and legal differences, particular local conditions and the particular needs of some branches of the industry may require the form to be adapted according to the particular needs of a project. And Civil law practitioners are strongly recommended to verify carefully the underlying legal concepts and background of each clause of the General Conditions in order to avoid unnecessary and sometimes unnatural changes and amendments being made. Note that when preparing the Particular Conditions ensure that terminology is consistent and that existing inherent concepts should not be ignored.

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Power Module Packaging Technology with Extended Reliability for Electric Vehicle Applications (전기자동차용 고신뢰성 파워모듈 패키징 기술)

  • Yoon, Jeong-Won;Bang, Jung-Hwan;Ko, Yong-Ho;Yoo, Se-Hoon;Kim, Jun-Ki;Lee, Chang-Woo
    • Journal of the Microelectronics and Packaging Society
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    • v.21 no.4
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    • pp.1-13
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    • 2014
  • The paper gives an overview of the concepts, basic requirements, and trends regarding packaging technologies of power modules in hybrid (HEV) and electric vehicles (EV). Power electronics is gaining more and more importance in the automotive sector due to the slow but steady progress of introducing partially or even fully electric powered vehicles. The demands for power electronic devices and systems are manifold, and concerns besides aspects such as energy efficiency, cooling and costs especially robustness and lifetime issues. Higher operation temperatures and the current density increase of new IGBT (Insulated Gate Bipolar Transistor) generations make it more and more complicated to meet the quality requirements for power electronic modules. Especially the increasing heat dissipation inside the silicon (Si) leads to maximum operation temperatures of nearly $200^{\circ}C$. As a result new packaging technologies are needed to face the demands of power modules in the future. Wide-band gap (WBG) semiconductors such as silicon carbide (SiC) or gallium nitride (GaN) have the potential to considerably enhance the energy efficiency and to reduce the weight of power electronic systems in EVs due to their improved electrical and thermal properties in comparison to Si based solutions. In this paper, we will introduce various package materials, advanced packaging technologies, heat dissipation and thermal management of advanced power modules with extended reliability for EV applications. In addition, SiC and GaN based WBG power modules will be introduced.

The Structural and Functional Role of p53 as a Cancer Therapeutic Target (암 치료 표적으로서 p53의 구조적 및 기능적 역할)

  • Han, Chang Woo;Park, So Young;Jeong, Mi Suk;Jang, Se Bok
    • Journal of Life Science
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    • v.28 no.4
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    • pp.488-495
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    • 2018
  • The p53 gene plays a critical role in the transcriptional regulation of cellular response to stress, DNA damage, hypoxia, and tumor development. Keeping in mind the recently discovered manifold physiological functions of p53, its involvement in the regulation of cancer is not surprising. In about 50% of all human cancers, inactivation of p53's protein function occurs either through mutations in the gene itself or defects in the mechanisms that activate it. This disorder plays a crucial role in tumor evolution by allowing the evasion of a p53-dependent response. Many recent studies have focused on directly targeting p53 mutants by identifying selective, small molecular compounds to deplete them or to restore their tumor-suppressive function. These small molecules should effectively regulate various interactions while maintaining good drug-like properties. Among them, the discovery of the key p53-negative regulator, MDM2, has led to the design of new small molecule inhibitors that block the interaction between p53 and MDM2. Some of these small molecule compounds have now moved from proof-of-concept studies into clinical trials, with prospects for further, more personalized anti-carcinogenic medicines. Here, we review the structural and functional consequences of wild type and mutant p53 as well as the development of therapeutic agents that directly target this gene, and compounds that inhibit the interaction between it and MDM2.

A Study of the Reduction of Diesel-Engine Emissions for Off-Road Vehicles (비도로 차량용 디젤엔진의 배기가스 저감에 관한 연구)

  • Cho, Gyu-Baek;Kim, Hong-Suk;Kang, Jeong-Ho
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.35 no.6
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    • pp.577-583
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    • 2011
  • To meet the requirements of the Tier 4 interim regulations for off-road vehicles, emissions of particulate matter (PM) and nitrogen oxides (NOx) must be reduced by 95% and 30%, respectively, compared to current regulations. In this research, both the DPF and HPL EGR systems were investigated, with the aim of decreasing the PM and NOx emissions of a 56-kW off-road vehicle. The results of the experiments show that the DOC-DPF system is very useful for reducing PM emissions. It is also found that the back pressure is acceptable, and the rate of power loss is less than 5%. By applying the HPL EGR system to the diesel engine, the NOx emissions under low- and middle-load conditions are reduced effectively because of the high differential pressure between the turbocharger inlet and the intake manifold. The NOx emissions can be decreased by increasing the EGR rate, but total hydrocarbon (THC) emission increases because of the increased fuel consumption needed to compensate for the power loss caused by EGR and DPF.