• Journal of Ginseng Research
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• v.41 no.1
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• pp.96-102
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• 2017

Background: Korean ginseng, Panax ginseng Meyer, has been used as a traditional oriental medicine to treat illness and promote health for several thousand years. Ginsenosides are the main constituents for the pharmacological effects of P. ginseng. Since several ginsenosides, including ginsenoside (G)-Rg3 and G-Rp1, have reported antiplatelet activity, here we investigate the ability of G-Rp4 to modulate adenosine diphosphate (ADP)-induced platelet aggregation. The ginsenoside Rp4, a similar chemical structure of G-Rp1, was prepared from G-Rg1 by chemical modification. Methods: To examine the effects of G-Rp4 on platelet activation, we performed several experiments, including antiplatelet ability, the modulation of intracellular calcium concentration, and P-selectin expression. In addition, we examined the activation of integrin ${\alpha}IIb{\beta}_3$ and the phosphorylation of signaling molecules using fibrinogen binding assay and immunoblotting in rat washed platelets. Results: G-Rp4 inhibited ADP-induced platelet aggregation in a dose-dependent manner. We found that G-Rp4 decreased calcium mobilization and P-selectin expression in ADP-activated platelets. Moreover, fibrinogen binding to integrin ${\alpha}IIb{\beta}_3$ by ADP was attenuated in G-Rp4-treated platelets. G-Rp4 significantly attenuated phosphorylation of extracellular signal-regulated protein kinases 1 and 2, p38, and c-Jun N-terminal kinase, as well as protein kinase B, phosphatidylinositol 3-kinase, and phospholipase C-${\gamma}$ phosphorylations. Conclusion: G-Rp4 significantly inhibited ADP-induced platelet aggregation and this is mediated via modulating the intracellular signaling molecules. These results indicate that G-Rp4 could be a potential candidate as a therapeutic agent against platelet-related cardiovascular diseases.

• Toxicological Research
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• v.12 no.1
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• pp.129-136
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• 1996

A fertility and general reproductive a. bility study was performed in Sparque-Dawley rats intravenously injected with Ginkgo biloba extract (EGb 761), a potential pharmaceutical excipient, at dose levels of 7.5, 15, and 30 mg/kg/day. Male rats were treated with Ginkgo biloba extract (EGb 761)from 14 days before mating until 21 days after delivery. Female rats received extract for 2 months prior to mating. No abnormal signs were noted in mating or fertility of the rats treated with Ginkgo biloba extract (EGb 761). No significant external, visceral, and skeletal anomalies or mental and physical development attributable to treatment was noted in any fetuses examined. The fertility of F1 generation was not affected by the treatment also. It was concluded that Ginkgo biloba extract (EGb 761) has no harmful effect on mating, fertilization, implantation, embryonic development and normal physical development.

• 한국체육학회지인문사회과학편
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• v.55 no.3
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• pp.15-25
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• 2016

This study attempted an eco-ethical approach to the sporting body, focusing on Toegye's Gyeong. A causes for the conflict between man and nature is a wrong view of nature derived from human desire. Toegye thought that the problem of desire could be overcome through Gyeong. Eco-ethical approaches of Toegye's gyeong thought are possible for the following reasons: First, because Toegye's gyeong is completed in nature. Second, because Toegye's gyeong emphasize human responsibility (consideration) for nature. Third, because gyeong is related to the ability to practice morality. Meanwhile, Toegye understood 'preserving the body well' as self-preservation and at the same time, as the meaning of a natural principle of following the laws of nature. From this perspective, the sporting body has meanings of physical fitness and mental health and at the same time, an aspect of ecological values of understanding man and nature as a single network and following the order of nature. Acquisition of Gyeong through the sporting body suggests the practice of 'gyeongsin (respect for the body)' and 'hwalgyeong (preservation of the ecological environment).' When human beings do physical exercise with nature, they proceed to the stage of building up the virtue of yosan yosu (finding happiness in mountains and water) through nature preserving the ecological environment (hwalgyeong) beyond staying at the stage of gyeongsin.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.2
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• pp.244-249
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• 2008

In this paper, we designed and fabricated the EM wave absorber consists of Sendust and Mn-Zn ferrite for suppressing EM wave noise from PCB in ISM(Industrial, Scientific and Medical) band of 2.4 GHz. We fabricated several samples in different ratios of Sendust to Mn-Zn ferrite with CPE(Chlorinated Ploy-ethylene) as binder and confirmed that optimum composition ratio of absorbing materials was Sendust. Mn-Zn ferrite : CPE=70:5:20 wt.%. The absorbing abilities were simulated according to different thickness of EM wave absorber as the function of material constants calculated by measured data. Measured absorption ability was analyzed and compared with simulated result. The simulated result agree well with the measured ones. As a result, the developed EM wave absorber with thickness of 0.85 mm has absorption ability of 5.4 dB at 2.4 GHz and over 3 dB in frequency rage of 1.4$\sim$4.1 GHz.

• Journal of the Korea Convergence Society
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• v.13 no.3
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• pp.379-390
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• 2022

The purpose of this study is to provide the basic data for improving the coping ability of clinical nurses by deeply analyzing and understanding the bioethics dilemma the clinical nurses experience in the COVID-19 pandemic. To understand the essence of bioethics dilemma the clinical nurses would experience in the COVID-19 pandemic, this study interviewed with a clinical nurse and then analyzed it by using Colaizzi (1978)'s phenomenological method. In the results of this study, total three theme clusters were drawn such as 'Agony to face a situation that violates the principle of respect for man's life and dignity', 'Frustration and confusion caused by the situation in which the principle of good deed and prohibition of evil deed cannot be kept', and 'Doubt about fulfilling and not fulfilling the principle of justice'. To improve the ability to cope with bioethics dilemma the clinical nurses experience in the pandemic situation based on the results of this study, it would be necessary to establish the education and policy for clinical nurses, and also to make efforts to improve the treatment of nurses.

• Journal of Navigation and Port Research
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• v.32 no.5
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• pp.349-353
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• 2008

In this paper, the EM wave absorber was designed and fabricated for preventing Reader Interference of RFID communication system in UHF band We fabricated several samples in different composition ratios of Amorphous and CPE(Chlorinated Polyethylene). Absorption abilities were simulated in accordance with different thicknesses of the prepared absorbers and changed complex relative permittivity and permeability due to composition ratio. The mixing ratio of Amorphous and CPE was searched as 80 : 20 wt.% by experiments and simulation. Then the EM wave absorber was fabricated and tested using the simulated data. As a result, the developed EM wave absorber has a thickness of 4 mm and absorption ability was over 20 dB in frequency range of $860\;MHz{\sim}960\;MHz$. Therefore, it was confirmed that the developed absorber can be used for suppressing RFID reader interference in UHF band.

• The Research Journal of the Costume Culture
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• v.15 no.3 s.68
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• pp.510-524
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• 2007

There is something common between the Korean female Kukkuk and the Japanese Takarazuka Revue in that actors are all females and love is the main theme. Some of the females should play men's roles, so they are described as ideal men and are more manly than real men, and female audiences are attracted by them. It is hard for actresses to play men's roles-they have to stretch open their shoulders, walk with long steps and produce a deep voice. They put on a makeup a little exaggeratedly to perfectly disguise themselves as men and express strong images-some red tone makeup on their face, thick eyebrows with their ends upward, thick eye lines to make eyes seem bigger and stronger, and thick side whiskers. On the contrary, a makeup for female characters is softer to highlight femininity with thin penciled hair parted and braided on the sides of the face. The Takarazuka Revue's students are divided into male characters and female ones from the regular course of music schools, and they select their roles in consideration of their height and range of voice, mainly based on their wish. In case of male characters, they need a long career and verification of ability to be the best. Females playing men's roles and showing their manliness are violation of a social custom standardizing the character of males and females and are the reverse of roles expected by a society or a culture. A world experienced by these plays is a kind of revolt breaking the taboo of the patriarchal system.

• The Journal of the Korea Contents Association
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• v.12 no.12
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• pp.510-516
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• 2012

Recently, along with mechanization, automation, modernization of industry, because of decrease in the conventional job that provide labor and receive wages, the industrial society that require production workers have become overcrowded. accordingly, the unemployeds are increasing. in the future, in preparation for IT, content industry that stand on the basis of knowledge industry, we have to develop competitive IT, content industry based on creativity. in the center of the progress, art education holds a special place. However, recent our education is so concentrated in college entrance examination that art education is losing its footing. this paper try to search the basis of creativity for future industry in the art education, emphasize the importance and invigoration of school art education. by the increase of artistic sensitivity that can be attained through art education, we can promote the whole man that can be creative, change one's way of thinking and develop the ability of carving one's way and leading future society. Therefore, we need future education that can promote the whole man that can be creative, change one's way of thinking through revitalized art education.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.18 no.10
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• pp.1136-1141
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• 2007

In this paper, we designed and fabricated EM wave absorbers using Sendust, $Al(OH)_3$ and CPE(Chlorinated Polyethylene). We compared the absorption properties of samples containing 0 wt.%, 3 wt.%, 5 wt.%, 7 wt.% of $Al(OH)_3$. The optimized composition ratio of $Al(OH)_3$ is 5 wt.%, and the absorption property curve just has the tendency to improve at 5 wt.% of $Al(OH)_3$. And we used this characteristics to design the double-layered EM wave absorber. The double-layered EM wave absorber has thickness of 2 mm and has absorption ability more than 18.5 dB at a wireless LAN frequency band using 2.4 GHz.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2009.10a
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• pp.54-55
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• 2009

The bandwidth of detecting radars used for military purpose is increasingly broadened, and recently, the frequency band of the detecting radars is expanding to millimeterwave bands c! the millimeterwave bands of 35 GHz and 94 GHz. Since, especially, it is essential and important to fabricate and develop EM wave absorber with the absorption ability more than 10 dB in 94 GHz band, the EM wave absorber was manufactured based on the design method by FDTD simulation As a result, the developed EM wave absorber with the composition ratio of Binder(CPE with additional materials) : Carbon = 70 : 30 wt.% has the thickness of 0.7 mm and the absorption ability more than 14 dB in the frequency range of 94 GHz.