• Molecules and Cells
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• v.37 no.8
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• pp.569-574
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• 2014

As a scaffold, SLX4/FANCP interacts with multiple proteins involved in genome integrity. Although not having recognizable catalytic domains, SLX4 participates in diverse genome maintenance pathways by delivering nucleases where they are needed, and promoting their cooperative execution to prevent genomic instabilities. Physiological importance of SLX4 is emphasized by the identification of causative mutations of SLX4 genes in patients diagnosed with Fanconi anemia (FA), a rare recessive genetic disorder characterized by genomic instability and predisposition to cancers. Recent progress in understanding functional roles of SLX4 has greatly expanded our knowledge in the repair of DNA interstrand crosslinks (ICLs), Holliday junction (HJ) resolution, telomere homeostasis and regulation of DNA damage response induced by replication stress. Here, these diverse functions of SLX4 are reviewed in detail.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2018.05a
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• pp.343-344
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• 2018

This study proposes a standard method of diagnosis and repair to prevent and maintain the problem of durability deterioration caused by leakage cracks in apartment basement structures in Korea. Following the announcement of the previous maintenance plan section, this is the second part of the study, focusing on inspection of methods for diagnosing and repairing leakage cracks in apartment basement structures. In this thesis, the matters required for the procedures, types, times and equipment of the inspection plan and the inspection methods, records, and decisions required for the actual inspection are described.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2018.11a
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• pp.191-192
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• 2018

This study presents the standard methods of diagnosis and repair to prevent and maintain the durability degradation caused by leakage cracks in underground structures in Korea. The third part after the announcement of the existing maintenance plan, The environmental characteristics and leakage condition of underground structures, the causes of deterioration of underground concrete structures, and countermeasures and leakage equipment were described.

• Industrial Engineering and Management Systems
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• v.2 no.1
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• pp.63-70
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• 2003

In this study, we employed an arithmetic process (AP) approach to resolve gearbox maintenance problems. The approach is realistic and direct in modelling the characteristics of a deteriorating system such as a gearbox since a decreasing AP can model a gearbox's successive operating times and an increasing AP can model the corresponding consecutive repair times. First of all, two test statistics were used to check whether the process is arithmetic or not. Next, model parameters of the AP were estimated using the simple linear regression method. Finally, the optimal replacement policy based on minimising the long-run average cost per day was determined for each type of gearbox.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.393-400
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• 2022

Agent-based modeling (ABM), as a relatively new simulation technique, has recently gained in popularity in the civil engineering domain due to its uniquely advantageous features. Among many civil engineering applications, ABM has been applied to facility operation and management, such as energy consumption management, as well as the enhancement of maintenance and repair processes. The former studies used ABM to manage energy consumption through simulating human energy-related behaviors and their interactions with facilities, as well as electrical, heating, and cooling systems and appliances, while the latter used ABM to enhance maintenance process through facilitating coordination, negotiation, and decision making between facility managers, service providers, and repair workers. The present study aims to provide a short qualitative review on the most recent applications of ABM in the above-mentioned areas. Based on the review and follow-up analysis, the study identifies the advantages, disadvantages, and limitations of ABM applications to facility operation and management, and offers several potential future research topics in the hope of filling the existing literature gaps.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2005.05a
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• pp.51-56
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• 2005

It does not find for solution by limitation of technological mechanism of existent of leakage maintenance material. So, it is paid for huge expense because continuous repeat maintenance work is consisting. Furthermore, it is indicated by big problem in construction work that is constructed by field experience that thing by definite and systematic theory is not with proper performance test and analysis up to now. Therefore, wish to measure physical performance change by various environment condition maintenance of structure and performance construction work aspect in that apply to water leakage maintenance material using of acrylic resin system water expansion, leakage maintenance material in this research, and present suitable form of construction work under these environment. also, wish to ready diversified remedy by oversea market opening.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2004.11a
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• pp.548-551
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• 2004

In suite of a high supply of multi-family housings, the government's housing policies have only been focusing on the construction of housings and their supply, while being almost indifferent to the maintenance management of them. As a result, a considerable amount of inconvenience to the use of housing resources and habitation of residents occurred. Accordingly, on this paper, the current housing policies and their inspections on the maintenance period are compared and analyzed with suggestions for improvement. Analysis shows that repairing of housings at appropriate time not only significantly delays the deterioration of housings, but also keeps the function of housings to their original condition. Therefore, through an efficient management of repair maintenance, wearing of buildings can be delayed and their functions can be improved.

• Proceedings of the KSR Conference
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• 2007.11a
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• pp.1158-1164
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• 2007

Recently, the demand on the practical application of life-cycle cost effectiveness for design and rehabilitation of civil infrastructure is rapidly growing unprecedentedly in civil engineering practice. Accordingly, it is expected that the life-cycle cost in the 21st century will become a new paradigm for all engineering decision problems in practice. However, in spite of impressive progress in the researches on the LCC, so far, most researches in Koreahave only focused on roadway bridges, which are not applicable to railway bridges. Thus, this paper presents the formulation models and methods for uncertainty-based LCCA for railroad bridges consideringboth objective statistical data available in the agency database of railroad bridges management and subjective data obtained form interviews with experts of the railway agency, which are used to anew uncertainty-based expected maintenance/repair costs including lifetime indirect costs. For reliable assessment of the life-cycle maintenance/repair costs, statistical analysis considering maintenance history data and survey data including the subjective judgments of railway experts on maintenance/management of railroad bridges, are performed to categorize critical maintenance items and associated expected costs and uncertainty-based deterioration models are developed. Finally, the formulation for simulation-based LCC analysis of railway bridges with uncertainty-based deterioration models are applied to the design-decision problem, which is to select an optimal bridge type having minimum Life-Cycle cost among various railway bridges types such as steel plate girder bridge, and prestressed concrete girder bridge in the basic design phase.

• Proceedings of the KSR Conference
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• 2007.11a
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• pp.1132-1140
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• 2007

As it recently appears that Life Cycle Cost Analysis may be considered as new methodology for economic valuation of infrastructure many researches have been made to assess LCC(Life Cycle Cost) of each facility based on a reasonable methods. In general, LCC is composed of construction cost and expected maintenance repair cost. And especially, maintenance repair cost must be estimated to enhance the reliability through systematic and reasonable methods. However in Korea, because high speed railway steel bridges are recently constructed no direct statistical data are available for the account of the maintenance cost and then their maintenance characteristics are not linear yet. Therefore, the approach proposed in the paper utilizes a theoretical determination and degradation of the corrosion and fatigue of the bridges based on Rahgozar et al.(2006)'s model on fatigue notch factor considering into the corrosion to incorporate the corrosion effect into the fatigue strength reduction model. And then, the corresponding probability of failure is calculated in terms of the reliability index using S-N curve to formulate the fatigue limit state. Therefore, this paper proposes the minimum Life Cycle Cost through optimum maintenance plan analysis of high-speed railway steel bridges under construction. Finally, this paper reviews the proposed model in oder to confirm the applicability and feasibility by appling it to high speed railway steel bridges under construction

• Journal of the Korean Society for Precision Engineering
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• v.34 no.1
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• pp.19-22
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• 2017

This paper describes the efficient equipment maintenance that can offer the exact time for repair and change of component in root industry. A conventional method offered the fixed time for repair and change of component because the method is based on early guarantee specification of the component. However the operating condition of manufacturing field is often under worse condition than early guarantee condition for high productivity. So, most components can't use until early guarantee time due to the operation of various different condition. Therefore we suggest the useful method for efficient equipment-maintenance by manufacturing-field analysis and feedback database. For this, the classification of root industry and related equipment is performed and then the detail classification of the process and component for equipment maintenance. And the monitoring module is also designed to gather data for feedback process and the environment is basically implemented for aging and reliability test.