• 제목/요약/키워드: magnesium, zinc excretion

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The Effect of Diabetes, Gestational Diabetes or Pre-eclampsia on Urinary Protein and Mineral Excretion during Pregnancy

  • Joo, Eun-Jung;Janet C. King
    • Preventive Nutrition and Food Science
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    • 제2권3호
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    • pp.225-231
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    • 1997
  • Thirteen healthy control, 13 pre-eclamptic, 7 diabetic(DM) and 12 gestational diabetic(GDM) pregnant women participated in a study ofthe interrelationships between the levels of protein, calcium, magnesium, phosphorus, zinc and copper in urine. Urinary protein, magnesium and copper levels were significantly higher (p<0.0005, p<0.0003, p<0.005 respectively) in pre-eclamptic women than those of control, DM and GDM women. Urinary zinc excretion in pre-eclamptic women (1.61 mg/g creatinine) was higher than that of DM women (0.81mg/g creatinine); urinary zinc losses of control and GDM women were wre between the other two rups. The GDM women excreted significantly ore phosphorus in their urine in comparison to control and preeclamptic women (p<0.02), but this was not seen in DM women. Among the DM women, urinary protein excretion was positively correlated with glycosylated hemoglobin(r=0.940) and fasting blood glucose concentration (r=0.889). Urinary zinc excretion also was correlated with glycosylated hemoglobin (r=0.853) and fasting blood glucose (r=0.956). In the GDM and pre-eclamptic women there were also significant correlations between urinar calcium and magnesium (r=0.857, r=0.749 respectively) and between urinary protein and copper(r=0.638, r=0.778 respectively).

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대두 이소플라본 보충과 운동이 폐경 후 여성의 소변 칼슘, 마그네슘, 구리, 아연 배설량에 미치는 영향 (Effects of Soy Isoflavones Supplementation and Exercise on Urinary Calcium, Magnecium, Copper and Zinc Excretion in Postmenopausal Women)

  • 윤미은;이다홍;김미현
    • Journal of Nutrition and Health
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    • 제41권7호
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    • pp.612-620
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    • 2008
  • 골다공증의 위험율이 높은 폐경 후 여성을 대상으로 이소플라본 보충과 운동의 단독 또는 복합적인 중재가 소변 칼슘, 마그네슘, 구리, 아연배설량에 미치는 영향을 알아보기 위하여 $45{\sim}67$세의 폐경 후 여성 67명을 연령, 체질량 지수와 Base line 골밀도에 차이가 없도록 대조군 (16명), 보충군 (19명), 운동군 (16명), 보충 + 운동군 (16명)으로 나누어 연구를 수행하였다. 보충 + 운동군과 보충군에게는 8주 동안 매일 이소플라본 90 mg을 보충하였으며 운동군과 보충+운동군에게는 함께 운동을 실시한 후 중재 전후의 소변 칼슘, 마그네슘, 구리, 아연 배설량 변화를 측정하여 다음과 같은 결과를 얻었다. 소변의 칼슘, 마그네슘, 구리의 배설량은 유의적인 변화를 보이지 않았다. 그러나 식이 아연의 섭취량이 운동과 이소플라본 보충을 실시하는 동안 변화가 없었음에도 불구하고, 이소플라본 보충군에서 소변 아연의 배설량이 유의적으로 감소하여 이소플라본의 보충이 골대사에 중요한 역할을 하는 아연 보유량을 증가시킨 것으로 나타났다. 이상의 결과를 통하여 폐경 후 여성에서 운동과 이소플라본의 동시 중재가 각각의 중재방법보다 골대사의 향상에 유의적인 상승 작용이 없음을 확인 할 수 있었다. 또한 이소플라본의 단독 보충군에서만 소변의 아연 배설량을 감소시키는 다소 미미한 연구 결과가 제시되었다. 그러나 본 연구는 연구 기간이 짧고, 이소플라본의 보충량이나 운동의 중재방법이 다양하지 못하다는 많은 제한점을 가지고 있으므로, 추후 효과적인 투여 농도와 운동중재 방법을 모색하고, 또한 운동과 기능성 식이성분의 효과적인 복합 중재 방법을 결정 할 수 있는 계속적인 연구가 필요하다고 본다.

Role of heavy metals in human health and particularly in respect to diabetic patients

  • Asif, Mohammad
    • 셀메드
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    • 제7권1호
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    • pp.1.1-1.10
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    • 2017
  • Minerals are individual of the components of foods and are not produced in the body but essential for best possible health. Several essential metals are vital for the appropriate performance of various enzymes, transcriptional factors and proteins that are essential in various biochemical paths. Metals like zinc (Zn), magnesium (Mg), and manganese (Mn) are cofactors of hundreds of enzymes. Zn is involved in the synthesis and secretion of insulin from the pancreatic ${\beta}-cells$. Chromium (Cr) increases the insulin receptors activity on target tissues, mainly in muscle cells. Insulin hormone is required to maintain the blood glucose amount in normal range. Continual increase of blood serum glucose level leads to marked chronic hyperglycemia or diabetes mellitus. Deficiency of insulin or its resistance, blood glucose level exceeds the upper limit of the common range of 126 mg/dl. Poor glucose control and diabetes changes the levels of essential trace elements such as Zn, Mg, Mn, Cr, iron etc. by rising urinary excretion and their related decrease in the blood. The aim of this article to discusses the important roles of essential trace elements in particular perspective of type 2 diabetes.

DIETARY SILICA EFFECTS ON MINERAL METABOLISM IN LAMBS

  • Prabowo, Akhmad;Spears, J.W.
    • Asian-Australasian Journal of Animal Sciences
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    • 제5권2호
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    • pp.279-283
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    • 1992
  • Eighteen wether lambs averaging 32 kg were used to determine the effects of dietary silica, added as silicic acid, on mineral metabolism. Lambs were fed 1200 g daily of a coastal Bermuda grass based diet supplemented with either 0, .5 or 1.5% silicic acid. A 7-d total collection of urine and feces was conducted after lambs had adjusted to the dietary treatments for 19 days. Urinary excretion of silica was higher (p<.01) in lambs fed added silicic acid. Ruminal soluble concentrations of manganese tended to be lower (p<.10) and apparent absorption and retention of manganese were lower (p<.05) in lambs supplemented with silicic acid compared to control lambs. Apparent absorption and retention of calcium were slightly lower (p<.10) in silicic acid fed lambs. No differences in urinary between lambs fed .5 and those given 1.5% silicic acid. Phosphorus, magnesium, iron, zinc and copper absorption and retention were not affected by treatment.

Effect of water scarcity during thermal-humidity exposure on the mineral footprint of sheep

  • Nejad, Jalil Ghassemi;Lee, Bae-Hun;Kim, Ji-Yung;Park, Kyu-Hyun;Kim, Won-Seob;Sung, Kyung-Il;Lee, Hong-Gu
    • Asian-Australasian Journal of Animal Sciences
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    • 제33권12호
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    • pp.1940-1947
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    • 2020
  • Objective: Combination of two stressors on alteration of mineral footprints in animals needs due attention to meet maximum production and welfare, particularly in grazing sheep. This study tested whether ewes (Ovis aries) exposed to water deprivation and thermal-humidity stressors had altered mineral footprints in their wool, serum, urine, and feces. Methods: Nine ewes (age = 3 years; mean body weight = 41±3.5 kg) were divided among a control group with free access to water, and treatment groups with water deprivation lasting either 2 h (2hWD) or 3 h (3hWD) after feeding. Using a 3×3 Latin square design, animals were assigned to treatment groups for three sampling periods of 21 days each (n = 9). Blood was collected by jugular venipuncture. Wool was collected at the end of periods 2 and 3. Metabolic crates designed with metal grated floors were used for urine and feces collection. We measured sodium (Na), magnesium (Mg), phosphorus (P), chloride (Cl), calcium (Ca), manganese (Mn), copper (Cu), iron (Fe), and zinc (Zn). Results: The wool mineral levels did not differ between the treatment groups, although K was marginally lower (p = 0.10) in the 2hWD group. The serum and urine mineral levels did not differ between the treatments (p>0.05). Fecal K was significantly lower in the 2hWD group than in the other groups (p≤0.05). Conclusion: In conclusion, water deprivation and thermal-humidity exposure altered the excretion of K, but not of other minerals, in the wool, urine, feces, or serum of ewes. Thus, no additional mineral supplementation is needed for water deprived ewes during thermalhumidity exposure.