• Title/Summary/Keyword: magnesium, zinc excretion

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The Effect of Diabetes, Gestational Diabetes or Pre-eclampsia on Urinary Protein and Mineral Excretion during Pregnancy

  • Joo, Eun-Jung;Janet C. King
    • Preventive Nutrition and Food Science
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    • v.2 no.3
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    • pp.225-231
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    • 1997
  • Thirteen healthy control, 13 pre-eclamptic, 7 diabetic(DM) and 12 gestational diabetic(GDM) pregnant women participated in a study ofthe interrelationships between the levels of protein, calcium, magnesium, phosphorus, zinc and copper in urine. Urinary protein, magnesium and copper levels were significantly higher (p<0.0005, p<0.0003, p<0.005 respectively) in pre-eclamptic women than those of control, DM and GDM women. Urinary zinc excretion in pre-eclamptic women (1.61 mg/g creatinine) was higher than that of DM women (0.81mg/g creatinine); urinary zinc losses of control and GDM women were wre between the other two rups. The GDM women excreted significantly ore phosphorus in their urine in comparison to control and preeclamptic women (p<0.02), but this was not seen in DM women. Among the DM women, urinary protein excretion was positively correlated with glycosylated hemoglobin(r=0.940) and fasting blood glucose concentration (r=0.889). Urinary zinc excretion also was correlated with glycosylated hemoglobin (r=0.853) and fasting blood glucose (r=0.956). In the GDM and pre-eclamptic women there were also significant correlations between urinar calcium and magnesium (r=0.857, r=0.749 respectively) and between urinary protein and copper(r=0.638, r=0.778 respectively).

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Effects of Soy Isoflavones Supplementation and Exercise on Urinary Calcium, Magnecium, Copper and Zinc Excretion in Postmenopausal Women (대두 이소플라본 보충과 운동이 폐경 후 여성의 소변 칼슘, 마그네슘, 구리, 아연 배설량에 미치는 영향)

  • Yun, Mi-Eun;Lee, Da-Hong;Kim, Mi-Hyun
    • Journal of Nutrition and Health
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    • v.41 no.7
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    • pp.612-620
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    • 2008
  • This study assessed the effects of soy isoflavones supplementation with exercise on urinary mineral (calcium, magnesium, copper, zinc) excretion as an index of bone resorption rates in 67 postmenopausal women. A total subjects were assigned to Isoflavone (90 mg/day) or placebo groups. These groups were further divided into groups that undergone a regular exercise or a rather sedentary state performing daily activity only. We conducted study eight week period. Result showed urinary zinc excretion was more significantly decreased in the isoflavone-sedentary group ($-180.76\;{\pm}\;171.30\;ug/day$) than in the placebo-sedentary group ($-31.23\;{\pm}\;146.60\;ug/day$), placebo-exercise group ($40.93\;{\pm}\;193.44\;ug/day$) and isoflavione-exercise group ($-1.21\;{\pm}\;160.61\;ug/day$) (p < 0.05), but no significant changes in the differences between the values of the pre and post study values in urinary calcium, magnesium and copper excretion. These results suggest that Isoflavone supplementation decrease urinary zinc excretion rate in postmenopausal subjects.

Role of heavy metals in human health and particularly in respect to diabetic patients

  • Asif, Mohammad
    • CELLMED
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    • v.7 no.1
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    • pp.1.1-1.10
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    • 2017
  • Minerals are individual of the components of foods and are not produced in the body but essential for best possible health. Several essential metals are vital for the appropriate performance of various enzymes, transcriptional factors and proteins that are essential in various biochemical paths. Metals like zinc (Zn), magnesium (Mg), and manganese (Mn) are cofactors of hundreds of enzymes. Zn is involved in the synthesis and secretion of insulin from the pancreatic ${\beta}-cells$. Chromium (Cr) increases the insulin receptors activity on target tissues, mainly in muscle cells. Insulin hormone is required to maintain the blood glucose amount in normal range. Continual increase of blood serum glucose level leads to marked chronic hyperglycemia or diabetes mellitus. Deficiency of insulin or its resistance, blood glucose level exceeds the upper limit of the common range of 126 mg/dl. Poor glucose control and diabetes changes the levels of essential trace elements such as Zn, Mg, Mn, Cr, iron etc. by rising urinary excretion and their related decrease in the blood. The aim of this article to discusses the important roles of essential trace elements in particular perspective of type 2 diabetes.

DIETARY SILICA EFFECTS ON MINERAL METABOLISM IN LAMBS

  • Prabowo, Akhmad;Spears, J.W.
    • Asian-Australasian Journal of Animal Sciences
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    • v.5 no.2
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    • pp.279-283
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    • 1992
  • Eighteen wether lambs averaging 32 kg were used to determine the effects of dietary silica, added as silicic acid, on mineral metabolism. Lambs were fed 1200 g daily of a coastal Bermuda grass based diet supplemented with either 0, .5 or 1.5% silicic acid. A 7-d total collection of urine and feces was conducted after lambs had adjusted to the dietary treatments for 19 days. Urinary excretion of silica was higher (p<.01) in lambs fed added silicic acid. Ruminal soluble concentrations of manganese tended to be lower (p<.10) and apparent absorption and retention of manganese were lower (p<.05) in lambs supplemented with silicic acid compared to control lambs. Apparent absorption and retention of calcium were slightly lower (p<.10) in silicic acid fed lambs. No differences in urinary between lambs fed .5 and those given 1.5% silicic acid. Phosphorus, magnesium, iron, zinc and copper absorption and retention were not affected by treatment.

Effect of water scarcity during thermal-humidity exposure on the mineral footprint of sheep

  • Nejad, Jalil Ghassemi;Lee, Bae-Hun;Kim, Ji-Yung;Park, Kyu-Hyun;Kim, Won-Seob;Sung, Kyung-Il;Lee, Hong-Gu
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.12
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    • pp.1940-1947
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    • 2020
  • Objective: Combination of two stressors on alteration of mineral footprints in animals needs due attention to meet maximum production and welfare, particularly in grazing sheep. This study tested whether ewes (Ovis aries) exposed to water deprivation and thermal-humidity stressors had altered mineral footprints in their wool, serum, urine, and feces. Methods: Nine ewes (age = 3 years; mean body weight = 41±3.5 kg) were divided among a control group with free access to water, and treatment groups with water deprivation lasting either 2 h (2hWD) or 3 h (3hWD) after feeding. Using a 3×3 Latin square design, animals were assigned to treatment groups for three sampling periods of 21 days each (n = 9). Blood was collected by jugular venipuncture. Wool was collected at the end of periods 2 and 3. Metabolic crates designed with metal grated floors were used for urine and feces collection. We measured sodium (Na), magnesium (Mg), phosphorus (P), chloride (Cl), calcium (Ca), manganese (Mn), copper (Cu), iron (Fe), and zinc (Zn). Results: The wool mineral levels did not differ between the treatment groups, although K was marginally lower (p = 0.10) in the 2hWD group. The serum and urine mineral levels did not differ between the treatments (p>0.05). Fecal K was significantly lower in the 2hWD group than in the other groups (p≤0.05). Conclusion: In conclusion, water deprivation and thermal-humidity exposure altered the excretion of K, but not of other minerals, in the wool, urine, feces, or serum of ewes. Thus, no additional mineral supplementation is needed for water deprived ewes during thermalhumidity exposure.