• The Korean Journal of Pain
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• 제35권4호
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• pp.413-422
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• 2022

Background: The neocortex, including the medial prefrontal cortex (mPFC), contains many neurons expressing nitric oxide synthase (NOS). In addition, increasing evidence shows that the nitric oxide (NO) and opioid systems interact in the brain. However, there have been no studies on the interaction of the opioid and NO systems in the mPFC. The objective of this study was to investigate the effects of administrating L-arginine (L-Arg, a precursor of NO) and N(gamma)-nitro-L-arginine methyl ester (L-NAME, an inhibitor of NOS) into the mPFC for neuropathic pain in rats. Also, we used selective opioid receptor antagonists to clarify the possible participation of the opioid mechanism. Methods: Complete transection of the peroneal and tibial branches of the sciatic nerve was applied to induce neuropathic pain, and seven days later, the mPFC was cannulated bilaterally. The paw withdrawal threshold fifty percent (50% PWT) was recorded on the 14th day. Results: Microinjection of L-Arg (2.87, 11.5 and 45.92 nmol per 0.25 µL) increased 50% PWT. L-NAME (17.15 nmol per 0.25 µL) and naloxonazine (an antagonist of mu opioid receptors, 1.54 nmol per 0.25 µL) inhibited anti-allodynia induced by L-Arg (45.92 nmol per 0.25 µL). Naltrindole (a delta opioid receptor antagonist, 2.45 nmol per 0.25 µL) and nor-binaltorphimine (a kappa opioid receptor antagonist, 1.36 nmol per 0.25 µL) were unable to prevent L-Arg (45.92 nmol per 0.25 µL)-induced antiallodynia. Conclusions: Our results indicate that the NO system in the mPFC regulates neuropathic pain. Mu opioid receptors of this area might participate in pain relief caused by L-Arg.

• 한국작물학회지
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• 제14권
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• pp.41-45
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• 1973

본 시험은 중부지방에서 담수직파재배에 알맞은 파종립수를 구명함과 파종립수에 EK른 수량 및 수량구성요소의 변이를 알고져 1972년에 수행하였던 바 그 결과를 요약하면 다음과 같다. 1. 최고분얼수는 밀파할수록 직선적으로 증가하여 280립 파종구에서 최고수치를 보였고 그 이후는 점차 감소되었으며 분얼에 대한 경합은 $m_2$당 280립이상 파종구에서 뚜렸했다. 2. 유효경비율은 $m_2$당 120립부터 280립 파종구까지는 파종밀도가 증가될수록 감소되다가 그 이후는 점차 증가되었다. 3. 최고분얼수가 $m_2$당 1,000개 이하에서는 얼자간 경합이 적었다. 4. 수수와 파종립수는 현저한정(+)의 상관이 인정되었고 수수와 일수영화수, 수수와 동숙비율은 (-)의 상관 경향이었다. 5. 수량과 $m_2$당 영화수는 r=0.929이며 수량과 수수는 r=0.695, 수수와 $m_2$당 영화수는 r=0.796이었다. 또한 수량과 수량구성요소간의 순위상관을 보면 수량과 수수가 가장 상관이 높았으며 (r=0.954_ 담수직파에서 수량을 지배하는 요인은 수수이었다. 6. 수량은 $m_2$당 280립 파종구에서 최고를 나타냈다.

• Journal of Radiation Protection and Research
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• 제42권4호
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• pp.222-228
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• 2017

Background: On June 18, 2017, Korea's first commercial nuclear reactor, the Kori Nuclear Power Plant No. 1, was permanently suspended, and the capacity of nuclear power generation facilities will be adjusted according to the governments denuclearization policy. In these circumstances, it is necessary to assess the quality of radiation safety management in nuclear power plants in Korea by evaluating the radiation dose associated with them. Materials and Methods: The average annual radiation dose per unit, the annual radiation dose per person, and the annual dose distribution were analyzed using the radiation dose database of nuclear reactors for the last 5 years. The results of our analysis were compared to the specifications of the Nuclear Safety Act and Medical Law in Korea. Results and Discussion: The annual average per unit radiation dose of global major nuclear power generation was 720 man-mSv, while that of Korea's nuclear power plants was 374 manmSv. No workers exceeded 50 mSv per year or 100 mSv in 5 years. The individual radiation dose according to occupational exposure was 0.59 mSv for nuclear workers, 1.77 mSv for non-destructive workers, and 0.8 mSv for diagnostic radiologists. Conclusion: The radiation safety management of nuclear power plants in Korea has achieved the best outcomes worldwide, which is considered to be the result of the as-low-as-reasonably-achievable (ALARA) approach and strict radiation safety management. Moreover, the occupational exposures were also very low.

• 한국가금학회:학술대회논문집
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• 한국가금학회 2001년도 제18차 정기총회 및 학술발표 PROCEEDINGS
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• pp.58-60
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• 2001

Two experiments were conducted to study the effects of nutrient level and feeding method of split diets for a.m. and p.m. on laying hen performance. In both studies, ISA Brown layers were kept in laying hen cages and treatments were represented by three or four replicates each containing 25 or 34 birds. In Experiment 1, the control group(C) was fed a conventional single diet throughout the day and split diet groups(T1, T2 and T3) were offered high energy/protein - low Ca diet and low energy/protein - high Ca diets in a.m. and p.m., respectively. In split diet groups, ME and CP consumption, and feed cost required per day and per kg egg mass were significantly reduced(P＜0.05) compared to C group, while the hen-day egg production, average egg weight and daily feed intake were not different among treatments. In the second study, C and T1 groups were fed the diets same to the C and T2 groups in Experiment 1, respectively. And T2 group was fed the diet mixed with the split diets for a.m. in mash and p.m. in pellet used in T1 group. In T1 and T2 groups, daily feed intake and average egg weight were significantly reduced(P＜0.05), while the hen-day egg production was not influenced by the feeding system. Daily ME and CP consumption, and feed cost were reduced(P＜0.05) in T1 and T2, while the ME, CP and feed cost required per kg egg mass were not different to the C group. In both study, eggshell qualities were improved(P＜0.05) by split diet feeding. It was concluded the feed and nutrients consumption, feed cost per day or per kg egg mass could be spared by introducing split diets for a.m. and p.m., and the feeding method of mixed diet of split diets was also convenient and effective for sparing feed cost and improvement of eggshell quality.

• 한국작물학회지
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• 제46권5호
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• pp.420-423
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• 2001

Combining ability in mungbean was studied in 15 quantitative traits through a 6 $\times$ 6 diallel cross. Both additive and non-additive gene effects were found conditioning the inheritane of nodes of the first peduncle, clusters per plant, clusters on main stem and branches, pods per plant, 1000 seed weight, grain yield per plant, biomass, and harvest index. The additive gene action was found significant for nodes on main stem, average internodal length, branches per plant, pods per cluster, pod length, and seeds per pod. The predominace of additive genetic variance was observed in all traits. For grain yield and yield components, the best combiner were VC3902A, VC1560D and ML-5, while the best combinations were the crosses VC3902A $\times$ ML-5, VC1560D $\times$ ML-5, and NM 92 $\times$ VC1560D.

• 농업과학연구
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• 제23권1호
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• pp.159-176
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• 1996

This study is aimed at reviewing the methods of joint cost allocation and allocating the joint cost of estuary dam with specially repect to Kumgang Large-scale Agricultural Comprehensive Development Project. Apart from the water resource development project propelled by Water Resource Development Corporation in connection with Law of Multipurpose Dam Development, the Largescale Comprehensive Agricultural Development Projects couldn't ins-titutionally be carried out cost allocation of common facilities, even though it were concerned with irrigation, municipal and industrical water supply, flood control, sightseeing and industrial zone development components. To decrease farmer's burden of the project costs and, operation and maintenance costs, the joint costs of common facilities like estuary dam included in agricultural development projects have to be allocated by suitable method as alternative cost-remaining benefit method and the analytical activity should be supported by revising the concerned laws as Rural Development and Promotion and, Rural Rearrangement conpatible with the law for multipurpose dam development. Kumgang Agricultural Comprehensive Development Project was selected as a case study for the estimation of socio-economic benefits by project components and joint cost allocation of the estuary dam. The main results of the study are as follows; Joint cost allocation and unit charges by components 1. The project area will be 25,554ha with total project cost of 624,860 million won including the estuary dam cost of 120,843 million won. The project costs were ex-pressed by 1994 constant price. 2. Total quantity of water was estimated 365 million tons which were consisted of 245 million tons for irrigation, 73 million tons for municipal water and 47 million tons for industrial water. 3. The rates of joint cost allocation were amounted to 34.2% for agriculture, 2.5% for sightseeing, 45.7% for transportation, 11.8% for M & I water supply and 5.8% for flood control respectively. 4. The unit financial charges by project components were estimated at 7.88 won per ton for irrigation, 16.11won for M & I water, 1,686won per vehicle one pass, 977won per Pyeong according to the capital recovery method. The financial charges using straitline method for depreciation were estimated at 7.88won per ton for irrigation, 9.12won per ton for M & I water, 624won per vehicle one pass for transportation and 331won per Pyeong for sightseeing area. 5. The unit economic charges by project components were estimated at 21.1 won per ton for irrigation, 15.2won for M & I water, 977won per vehicle one pass, 977won per Pyeong according to the capital recovery method. The economic charges using straitline method for depreciation were estimated at 11.72won per ton for irrigation, 8.61won per ton for M & I water, 331won per vehicle one pass for transportation. Policy recommendation 1. The unit operation and maintenance costs for irrigation water in the paddy field couldn't be imposed as the water resource cost untreated. 2. The dam costs including investment cost and O & M cost, as a joint cost, had to be allocated by each benefited components as transportation, M & I water supply, flood control, irrigation and drainage, and sightseeing. But the agricultural comprehensive project have been dealt as an irrigation project without any appraisal socio-economic benefits and any allocating the joint cost of estuary dam. 3. All the associated project benefits and costs must be evaluated based on accounting principle and rent recovery rate of the project costs and O & M costs should be regulated by the laws concerned. 4. The rural development and promotion law and rural rearrangement law have to be revised comprising joint cost allocation considering free rider problems. 5. The government subsidy for the agricultural base development project has to be covered all the project costs. In case of common facilities representing joint cost allocation problems, all the allocated casts for other purposes like transportation and M & I water supply etc. should be recovered for formation in investment fund for agricultural base development and to procure O & M costs for irrigation facilities.

• Journal of Nutrition and Health
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• 제24권1호
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• pp.48-57
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• 1991

The longitudinal changes on human milk volume per day and lactational performance of Korean primiparae(n=9) and multiparae(n=6) from 0.5 month to 5 months after parturition have been studied by test-weighing method. The human milk volume per day tended to increase during lactation. The mean volume to the 3rd month of lactation was 643m1 for primiparae and 654m1 for multiparae, and it was 647 $\pm$ 182m1 for both of them. The mean volume to the 5th month of lactation was 648m1 for primiparae and 668m1 for multiparae, and it was 658$\pm$186$m\ell$ for both of them. The peak volume was observed at the 1st month of lactation in 8 women of 15 lactating women, that is, 53.3% . The high distributions of the individual mean volume to the 5th month were found 550~650$m\ell$(40.0% ) and 650~750$m\ell$(26.7% ). and 13 women of 15 lactating women(86.6% ) were observed below 750m1. The number of feeding per day was 7.7~9.3 to the 5th month and the mean volume per feeding was 65~101$m\ell$. While the former tended to decreased, the latter increased during lactation. The human milk volume was correlated with the peak volume. but not with maternal age. weight before delivery. maternal height and birth weight. As mentioned above, the human milk volume of Koreans was about 658$\pm$ 186$m\ell$ and 86.6% of it was below 750$m\ell$. So the human milk volume, referred to as 800$m\ell$ in recommended dietary allowances for Koreans might be estimated over real amount. It is necessary to study according to regions. socioeconomic levels. maternal nutritional status and the early stage of lactation.

• 환경영향평가
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• 제22권6호
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• pp.557-568
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• 2013

In this study, Calculated the nonpoint sources(NPS) load per unit area about various rainy events in vineyard of Nakdong River basin. NPS monitoring and calculation for NPS load per unit area were estimated from 'Investigation method of precipitation discharge(National Institute of Environmental Research, 2007)'. The evaluation of applicability for NPS load per unit by compared with prior research data and Total Maximum Daily Load(TMDL) data. Five target areas were each $2000m^2$, $1800m^2$, $1943m^2$, $2484m^2$, $864m^2$ and located in Gyeongsangbukdo Gyeongju, Gyeongsangbukdo Sangju, Gyeongsangnamdo Hapcheon in Korea. Since fruits were the only crop on the target area, the characteristics of stormwater discharge at survey sites could be evaluated independently. A total of 115 rainfall events in the Orchard area during five years(2008-2012) was surveyed, and 38 of them became stormwater discharge. In the Nakdong River watershed, average of event mean concentrations(EMCs) in Orchard area for biochemical oxyzen demand(BOD), Chemical oxyzen demand(COD), total nitrogen(T-N), total phosphorus(T-P) were 2.0mg/L, 10.1mg/L, 3.195mg/L, 0.578mg/L, respectively. NPS load per unit area in Orchard area showed BOD : $2.0kg/km^2{\cdot}day$, COD : $10.2kg/km^2{\cdot}day$, T-N : $3.220kg/km^2{\cdot}day$, T-P : $0.606kg/km^2{\cdot}day$.

• 환경위생공학
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• 제4권2호
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• pp.47-59
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• 1989

In order to investigate the bacteriological contamination of water in Han river, the survey was carried out in eight reservoirs of Seoul water supply during the period from January to December in 1985. 1. The counts by means of total bacteria in eight reservoirs by standard plate count method were as follows: $7.7\times10^2$ per ml in Paldang reservior, $9.6\times10^3$ per ml in Gueiri, $8.4\times10^4$ per ml in Doogdo, $1.6\times10^6$ per ml in Bogwang, $2.5\times10^6$ per ml in Noryangjin, $2.2\times10^6$per ml in Seon yoo, $5.9\times10^6$ per ml in Yungdeungpo and $1.9\times10^7$per ml in Gayang. 2. The average counts of total coliform in eight reservoirs by MPN method were as follows : $2.4\times10$ per 100 ml in Paldang, $5.6\times10^2$ per 100 ml in Gueiri, $2.3\times10^3$ per 100 ml in Doogdo, $5.1\times10^4$ per 100 ml in Noryang-jin, $1.2\times10^5$ per 100 ml in Bogwang, $6.2\times10^4$ per 100 ml in Seonyoo, $1.1\times10^5$ per 100 ml in Yungdeungpo and $2.8\times10^5$ per 100 ml Gayang. 3. The counts by means of fecal coliform in eight reservoirs by MPN method were as follows : non detection per 100 ml in Paldang, 5.2 per 100 ml in Gueiri, $1.2\times10^2$ per 100 ml in Doogdo, $1.6\times10^3$ per 100ml in Bogwang, $2.0\times10^3$per 100ml in Noryangjin, $6.6\times10^2$ per 100ml in Seonyoo, $1.2\times10^3$ per 100 ml in Yungdeungpo and $2.5\times10^3$per 100 ml in Gayang. 4. The counts by means of fecal streptococci in eight reservoirs by MPN method were as follows: non detection per 100 ml in Paldang and Gueiri, $6.9\times10$ per 100 ml in Doogdo, $3.2\times10^2$ 102 per 100 ml in Bogwang, $2.9\times10^2$ per 100 ml in Noryangjin, $3.0\times10^2$ per 100 ml in Seonyoo, $4.0\times10^2$ per 100 ml in Yungdeungpo and $14\times10^3$ per 100 ml in Gayang. 5. The counts means of pseudomonas aeruginosa in eight reservoirs by MPN method were as follows; non detection per 100 ml in Paldang, 2.4 per 100 ml in Gueiri, $1.5\times10$ per 100 ml in Doogdo, $2.0\times10$ per 100ml in Bogwang,$6.2\times10$ per 100mI in Noryangjin, $2.1\times10$ per 100ml in Seonyoo, $6.4\times10$ per 100mI in Yungdeungpo and $7.1\times10$ per 100ml in Gaynag.

• 한국산학기술학회논문지
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• 제16권4호
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• pp.2924-2932
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• 2015

본 연구는 초등학교, 중학교 및 고등학교의 급수설비 사용수량의 분석 통해 급수량 산출자료를 추정하여 학교시설 급수시스템의 적정 급수계획에 필요한 기초자료를 얻고자 하였다. 이를 위하여, 강원지역 6개 도시에 소재하는 초 중 고등학교 54개 학교를 대상으로 5년간의 급수설비 사용수량을 분석하였다, 분석결과, 1) 월평균 사용수량의 평균은 $600.7(m^3/mon)$이었으며, 초등학교와 중학교가 $484.2(m^3/mon)$, 고등학교가 $833.8(m^3/mon)$로 분석 되었다. 2) 학급당 월평균 사용수량의 평균은 $27.0(m^3/mon/class)$이었으며, 초등학교와 중학교가 $24.4(m^3/mon/class)$, 고등학교가 $32.(m^3/mon/class)$로 분석 되었다. 3) 1인1일 평균 사용수량의 평균은 55.8(l/c/d)이었으며, 초등학교와 중학교가 54.4(l/c/d), 고등학교가 58.6(l/c/d)로 분석 되었다.