• Korean Journal of Food Science and Technology
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• v.27 no.5
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• pp.666-672
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• 1995

This study was carried out to characterize thermolabile pectinesterase (TLPE) and thermostable pectinesterase (TSPE) separated from crude PE of Valencia orange in order to investigate the preventive measures of cloudy juice clarification. The TLPE was observed to be mixture of several isoenzymes with the same molecular weight of 36 KD (37.5 KD) but different isoelectric point of pH 8.4, 8.7, 8.9, 9.8 and ${\geq}10$ which were unstable at $70^{\circ}C$, and the TSPE also was found to be mixture of two or three isoenzymes with the same molecular weight of 53 KD (50 KD) but different isoelectric point of pH 8.7, 9.2 and ${\geq}10$ which had slightly different stability from one another at $70^{\circ}C$. The TLPE and the TSPE had the optimum reaction pH of 7.0 and $7.0{\sim}8.5,\;appK_{M}$ of 1.1 and 1.7 mg/ml, appVmax of 0.53 and $1.01\;{\mu}mol/min/{\mu}g$, and the turnover number of 19.000 and 54,000 mol/mol/min toward Kodak pectin, respectively. The TSPE had higher storage stabiblity and cloud loss effect on orange juice than the TLPE. Above all, the crude PE was most effective on orange juice cloud loss among the PEs used.

• Proceedings of the Korea Information Processing Society Conference
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• 2010.11a
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• pp.72-75
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• 2010

Google을 시작으로 포털 사이트들이 Maps API를 공개하면서 맵 응용에 대한 수요가 급증하고 있다. 맵 응용의 개발은 대부분 수작업으로 이루어지고 있기 때문에 맵 응용의 생산성이 떨어질 뿐만 아니라 유지 보수에도 많은 시간과 노력이 요구되고 있다. 우리가 설계하고 구현한 MapAppGen은 ModuleGen, IndexGen, MapGen으로 구성되며 맵 응용을 자동으로 생성한다. MapAppGen은 Google Maps API를 사용하여 CMS(Content Management System) 중의 하나인 Drupal에 적용 가능한 모듈들을 생성해 맵 응용에 대한 생산성을 향상시켜 준다. MapAppGen처럼 맵 응용을 위해 Drupal 모듈을 생성하는 생성기는 현재 존재하지 않으며 Gmap이나 NodeMap과 같이 고정된 맵 인터페이스 모듈들은 존재한다. 그러나 Gmap이나 NodeMap 모듈은 Drupal의 기본 컨텐츠 타입 모듈에 의존하기 때문에 사용자는 원하는 지형/지물 컨텐츠 타입을 생성해 활용할 수 없고 지형/지물들을 유형별로 맵 상에 표시하고 연관된 컨텐츠들을 검색할 수도 없다.

• Elastomers and Composites
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• v.49 no.2
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• pp.110-116
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• 2014

We investigated the effect of the concentration of stannous 2-ethylhexanoate catalyst on the esterification rate between adipic acid (AA) and each of two PEG oligomers, diethylene glycol (DEG) and polyethylene glycol (PEG600). The concentration of the catalyst was varied from 0.15 to 2.0 wt.%. To attach hydroxy group to each end of the poly(oxyethylene-co-adipate) synthesized from AA and the PEGs, the esterification was performed with excessive PEG oligomers ([PEG]/[AA]=2) at $170^{\circ}C$. The degree of polymerization of the poly(oxyethylene-co-adipate)diol products were three. The apparent rate constant ($k_{app}$) of the esterification between AA and DEG shows the first order dependency on the catalyst concentration ($k_{app}=0.88[C_{cat}]$), whereas the $k_{app}$ of the esterification between AA and PEG600 has a relation of $k_{app}=0.123[C_{cat}]^{0.55}$ with the catalyst concentration. It is expected that the rate of esterification between AA and DEG has a non-linear dependency on the catalyst concentration as the catalyst concentration approaches to 0.22M.

• Journal of Oriental Neuropsychiatry
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• v.13 no.1
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• pp.79-115
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• 2002

This research investigates the effect of the Crataegus pinnatifida BGE. var. major N.E. BR(CPVM) on Alzheimer's disease. Specifically, the effects of the DYHT extract on (1) $IL-1{\beta}$, IL-6, amyloid precursor proteins(APP), acetylcholinesterase(AChE), and glial fibrillary acidic protein(GFAP) mRNA of PC-12 cells treated with CTI05; (2) the AChE activity and the APP production of PC-12 cell treated with CT105; (3) the behavior; and (4) expression of $IL-1{\beta}$, $TNF-{\alpha}$, reactive oxygen species(ROS), nitrite oxide(NO); and (5) the infarction area of the hippocampus, and brain tissue injury in Alzheimer's diseased mice induced with CT105 were investigated. The results are as follow. 1. The CPVM extract suppressed the expression of $IL-1{\beta}$, IL-6, APP, AChE, and GFAP mRNA in PC-12 cells treated with CT105. 2. The CPVM extract suppressed the AChE activity and the production of APP significantly in PC-12 cells treated with CT105. 3. The CPVM extract group showed a significant inhibitory effect on the memory deficit for the mice with Alzheimer's disease induced by CT105 in the Morris water maze experiment. 4. The CPVM extract suppressed the over-expression of $IL-1{\beta}$, $TNF-{\alpha}$, ROS and NO in the mice with Alzheimer's disease induced by CT105. 5. The CPVM extract reduced the infarction area of hippocampus, and controlled the injury of brain tissue in the mice with Alzheimer's disease induced by CT105. These results suggest that the CPVM extract may be effective for the prevention and treatment of Alzheimer's disease.

• BMB Reports
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• v.43 no.10
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• pp.704-709
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• 2010

The Swedish mutation (K595N/M596L) of amyloid precursor protein (APP-swe) has been known to increase abnormal cleavage of cellular APP by Beta-secretase (BACE), which causes tau protein hyperphosphorylation and early-onset Alzheimer's disease (AD). Here, we analyzed the effect of APP-swe in global gene expression using deep transcriptome sequencing technique. We found 283 genes were down-regulated and 348 genes were up-regulated in APP-swe expressing H4-swe cells compared to H4 wild-type cells from a total of approximately 74 million reads of 38 base pairs from each transcriptome. Two independent mechanisms such as kinase and phosphatase signaling cascades leading hyperphosphorylation of tau protein were regulated by the expression of APP-swe. Expressions of catalytic subunit as well as several regulatory subunits of protein phosphatases 2A were decreased. In contrast, expressions of tau-phosphorylating glycogen synthase kinase $3\beta$(GSK-3$\beta$), cyclin dependent kinase 5 (CDK5), and cAMP-dependent protein kinase A (PKA) catalytic subunit were increased. Moreover, the expression of AD-related Aquaporin 1 and presenilin 2 expression was regulated by APP-swe. Taken together, we propose that the expression of APP-swe modulates global gene expression directed to AD pathogenesis.

• Journal of Korea Game Society
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• v.18 no.3
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• pp.27-38
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• 2018

This paper is designed to propose the contents necessary for updating and developing future mobile RPG game developers through a usability evaluation of Users using In-App Payment Services at Lineage M. This paper conducted a usability assessment for quantitative assessment of users who use in-app payment services for mobile game 'Lineage M'. The tool for usability assessment was surveyed in a questionnaire designed based on 'The User Experience Honeycomb' defined by Peter Morville. These statistical results were then divided into lateral analyses. Through this, it is expected that game developers and planners will be able to find data to help develop new mobile RPG games.

• Journal of the Korean Society of Groundwater Environment
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• v.1 no.1
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• pp.23-32
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• 1994

To determine the apparent equilibrium constants, K$_{ad,app}$, for the adsorption reactions of trace metals on amorphous iron oxyhydroxide (AIO) in the Taebag coal mine area, time-adsorption and pH-adsorption experiments were performed for a selected bottom sediment mainly comprised of AIO from the study area. The results from the adsorption experiments indicate that most of the trace metals, except Pb, achieve equilibrium states with AIO and thus, the calculated K$_{ad,app}$ may represent the true apparent equilibrium constants. K$_{ad,app}$ and the stoichiometric coefficients of proton, x, of the adsorption reactions between the trace metals and AIO were respectively calculated from the intercepts and slopes of the regression lines of log($\Gamma$/ ［M］$_{aq}$)against pH provided by pH-adsorption experiments. The calculated K$_{ad,app}$ this study has the values of the range from 10$^{－4.5}$ to 10$^{2.75}$ , which is much different from the reported values by other investigators for simple experimental systems. K$_{ad,app}$ of this study is more or less close but not exactly pertinent to the estimated values for the other natural systems. It indicates that K$_{ad,app}$ for the adsorption reactions in the aquatic system in the study area is unique and thus should be determined befor the adsorption modelling. The calculated x of this study has the values of the range from -0.3 to 0.7, which is also much different from what most geochemists generally accept. The discrepancy in x may be due to the competition among different kinds of ionic species on the adsorption site or simulataneous occurrence of different kinds of adsorption reactions. The results from this study should help construct an appropriate adsorption model for the aquatic systems polluted by the coal mine drainage in the Taebag area. With the constructed model, one can describe the concentration variations of trace metals due to the adsorption in the system, which is an essential part of the investigation on the water quality affected by coal mine drainage in the Taebag coal field.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.04a
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• pp.515-517
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• 2015

본 연구는 블록 형태의 프로그래밍 툴인 앱 인벤터를 이용해 학생들의 학업에 대한 정보와 궁금증을 해결해 줄 수 있는 인터넷 강의평가 앱 개발을 연구하였다. 앱을 개발하는 과정에서 웹 데이터베이스와 구글 퓨전 테이블을 이용하여 로그인 기능과 사용자들에게 공유하여 볼 수 있는 게시판 기능을 추가하였다. 이 기능을 통하여 사용자간에 정보를 공유하여 인터넷강의 선정에 정보제공 방법을 연구하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.1158-1159
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• 2013

It gives to users a difficulty for searching between this huge numbers of programs. Searching the best applications for our needs is a big challenge today. In this paper, we propose a study on collaborative filtering based app recommendation system. The proposed method is composed of three steps. In the first step, we extract the data set from the target website. In the second step, we parse the extracted raw data according to the types, and store in a database. In the third, we perform recommendations based on the stored data in database.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.11a
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• pp.1113-1114
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• 2011

본 연구에서는 텍스트 중심의 e-book에서 나아가 비디오 콘텐트가 융합된 HTML5 기반의 양방향 videobook을 구현하였다. 이를 위하여 기존 videobook의 사례를 바탕으로 콘텐트 유형 및 구성요소를 도출하고, 기존 인터랙션 양식 기반으로 videobook 인터랙션을 설계한 후 HTML5를 바탕으로 구현하였다.