• Title/Summary/Keyword: low radiation

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Effect of Red Ginseng on Radiation-induced Learning and Memory Impairment in Mouse (방사선 조사 마우스에서 학습기억 장애에 대한 홍삼의 효과)

  • Lee, Hae-June;Kim, Joong-Sun;Moon, Chang-Jong;Kim, Jong-Choon;Jo, Sung-Kee;Jang, Jong-Sik;Kim, Sung-Ho
    • Journal of Ginseng Research
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    • v.33 no.2
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    • pp.132-138
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    • 2009
  • Previous studies suggest that even low-dose irradiation can lead to progressive cognitive decline and memory deficits, which implicates, in part, hippocampal dysfunction in both humans and experimental animals. In this study, whether red ginseng (RG) could attenuate memory impairment was investigated through a passive-avoidance and object recognition memory test, as well as the suppression of hippocampal neurogenesis, using the TUNEL assay and immunohistochemical detection with markers of neurogenesis (Ki-67 and doublecortin (DCX)) in adult mice treated with a relatively low-dose exposure to gamma radiation (0.5 or 2.0 Gy). RG was administered intraperitonially at a dosage of 50 mg/kg of body weight, at 36 and 12 h pre-irradiation and at 30 minutes post-irradiation, or orally at a dosage of 250 mg! kg of body weight/day for seven days before autopsy. In the passive-avoidance and object recognition memory test, the mice that were trained for one day after acute irradiation (2 Gy) showed significant memory deficits compared with the sham controls. The number of TUNEL-positive apoptotic nuclei in the dentate gyrus (DG) was increased 12 h after irradiation. In addition, the number of Ki-67- and DCX-positive cells was significantly decreased. RG treatment prior to irradiation attenuated the memory defect and blocked apoptotic death as well as a decrease in the Ki-67- and DCX-positive cells. RG may attenuate memory defect in a relatively low-dose exposure to radiation in adult mice, possibly by inhibiting the detrimental effect of irradiation on hippocampal neurogenesis.

A study on the radiation effect of silicon solar cells in a low Earth orbit satellite by using high energy electron beams (고에너지 전자빔을 이용하여 저궤도 인공위성의 실리콘 태양센서의 내방사선 특성 연구)

  • Chung, Sung-In;Lee, Jae-Jin;Lee, Heung-Ho
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.45 no.3
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    • pp.1-5
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    • 2008
  • This paper analyzes on the radiation effect of silicon solar cells in a low Earth orbit satellite by using high energy electron beams. Generally, the satellite circling round in a low orbit go through Van Allen belt, in which electronic components are easily damaged and shortened by charged particles moving in a cycle between the South Pole and the North Pole. For example, Single Event Upset (SEU) by radiation could cause electronic devices on satellite to malfunction. From the ground experiment in which we used the high energy electron beam facility at Knrea Atomic Energy Research Institute (KAERI), we tried to explain sun sensor degradations on orbit could he caused by high energy electrons. While we focused on the solar cells used for light detectors, We convince our research also contributes to understand the radiation effect of solar cells generating electric powers on satellites.

Radiation Hormesis on the Growth of Chinese Cabbage and Radish (전리방사선에 의한 배추와 무의 생육촉진효과)

  • Kim, Jae-Sung;Kim, Jin-Kyu;Lee, Eun-Kyung;Lee, Young-Bok
    • Korean Journal of Environmental Agriculture
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    • v.16 no.4
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    • pp.390-393
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    • 1997
  • Hormetic effects of low dose radiation were analyzed in terms of growth stimulation in radish and three cultivars of chinese cabbage. Seeds irradiated with ${\gamma}$ radiation were planted in the green house and in the experimental field. Though it varied with cultivars of tested plants, hormetic effect of low dose ${\gamma}$ radiation on an early stage of growth were shown especially in germination rates and elongation of seedlings. The height of seedlings increased in 0.2 Gy irradiated group of Seolim cultivar and radish, in 1 Gy irradiated group of Konaenggi cultivar and in 4 Gy irradiated group of Ducksung cultivar, respectively, In case of plants grown in the experimental field, prominent were the height increase of radish and Seolim cultivar in 1 Gy irradiated group and the fresh weight increase of both radish and cabbage in 4 Gy irradiated group.

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Comparison of the Result of Radiation Alone and Radiation with Daily Low Dose Cisplatin in Management of Locally Advanced Cervical Cancer (국소적으로 진행된 자궁경부암에서 방사선 단독치료와 방사선 및 저용량 Cisplatin 항암화학요법 병용치료의 비교)

  • Kim Hun Jung;Kim Woo Chul;Lee Mee Jo;Kim Chul Su;Song Eun Seop;Loh John J K.
    • Radiation Oncology Journal
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    • v.22 no.3
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    • pp.200-207
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    • 2004
  • Purpose: An analysis was to compare the results of radiation alone with those of radiation with dally low dose cisplatin as a radiation sensitizer in locally advanced cervical cancer. Materials and Methods: A retrospective analysis of 59 patients diagnosed with locally advanced uterine cervix cancer between December 1996 and March 2001 was peformed. Thirty one patients received radiation alone and 28 patients received dally low dose cisplatin, as a radiation sensitizer, and radiation therapy. The median follow-up period was 34 months, ranging from 2.5 to 73 months. The radiation therapy consisted of 4500 cGy external beam irradiation to the whole pelvis (midline block after 3060 cGy), a 900$\~$l,000 cGy boost to the involved parametrium and high dose-rate intracavitary brachytherapy (a total dose of 3,000$\~$3,500 cGy/500 cGy per fraction to point A, twice per week). In the chemoradiation group, 10 mg of daily intravenous cisplatin was given daily from the 1st day of radiation therapy to the 20th day of radiation therapy. According to the FIGO classification, the patients were subdivided into 51 (86.4$\%$) and 8 (13.6$\%$) stages IIB and stage IIIB, respectively. Results: The overall 5 year survival rate was 65.65$\%$ and according to treatment modality were 56.75$\%$ and 73.42$\%$ in the radiation alone and chemoradiation groups, respectively (p=0.180). The 5 year disease-free survival rates were 49.39$\%$ and 63.34$\%$ in the radiation alone and chemoradiatoin groups, respectively (p=0.053), The 5 year locoregional control rates were 52.34$\%$ and 73.58$\%$ in the radiation alone and chemoradiation groups, respectively (p=0.013). The 5 year distant disease-free survival rates were 59.29$\%$ and 81.46$\%$ in the radiation alone and chemoradiation groups, respectively (p=0.477), Treatment related hematologic toxicity were prominent in the chemoradiation group. Leukopenia $\geq$grade) occurred in 3.2$\%$and 28.5$\%$ of the radiation alone and chemoradiation groups, respectively (p=0.02). There were no statistical differences in the incidences of vesical, rectal and small bowel complications between two groups. Conclusion: Radiation therapy with low dose cisplatin did not improve the rates of survival and response rates, but did improve the rate of disease free survival and locoregional control rates In locally advanced cervical cancer. The incidence of bone marrow suppression was higher in the chemoradiation group.

Dosimetric characteristics of an independent collimator system using measurements performed quarter fields. (Tungsten eyeball shield block의 임상적용에 관한 고찰)

  • Jeong, Deok-Yang;Lee, Byoung-Koo;Hwang, Woong-Koo
    • The Journal of Korean Society for Radiation Therapy
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    • v.14 no.1
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    • pp.89-94
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    • 2002
  • During radiation therapy with electron beam to eyelid, we must keep the minimal dose on eyeball as possible. especially in the treatment of Sebaceous gland carcinoma, Squamouse cell ca., and basal cell ca. of eyelid and low grade MALToma etc. But if radiation field covered the upper & lower eyelid, it makes a cataract on lens of treated eye, in late complications. Now we reports the advantages of Tungsten eyeball shielding block compare to previously used lead block. with BOLX-I material, we made a eyeball model and measured the absorbed dose of 6MeV & 9MeV electron hem at 6 point of eyeball model with TLD chip. And compare the absorbed dose to previously lead block and other types of Tungsten eyeball shielding block.

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Number of Mediastinal Lymph Nodes as a Prognostic Factor in PN2 Non Small Cell Lung Cancer: A Single Centre Experience and Review of the Literature

  • Takanen, Silvia;Bangrazi, Caterina;Graziano, Vanessa;Parisi, Alessandro;Resuli, Blerina;Simione, Luca;Caiazzo, Rossella;Raffetto, Nicola;Tombolini, Vincenzo
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7559-7562
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    • 2014
  • Currently the most important prognostic factor in lung cancer is the stage. In the current lung TNM classification system, N category is defined exclusively by anatomic nodal location though, in other type of tumours, number of lymph nodes is confirmed to be a fundamental prognostic factor. Therefore we evaluated the number of mediastinal lymph nodes as a prognostic factor in locally advanced NSCLC after multimodality treatment, observing a significant effect of the number of lymph nodes in terms of OS (p<0.01) and DFS (p<0.001): patients with a low number of positive mediastinal nodes have a better prognosis.

A Study on the Analysis of Solar Radiation Characteristics on a High Elevated Area (고지대 일사량 특성분석에 관한 연구)

  • Jo, Dok-Ki;Kang, Young-Heack;Auh, Chung-Moo
    • Journal of the Korean Solar Energy Society
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    • v.23 no.3
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    • pp.23-28
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    • 2003
  • The purpose of this study is to procure basic data to be used for solar power plant and concentrating collector designs. Site elevation is one of the major factors which influences the incoming insolation to the earth surface. Because the nonpermanent gases such as ozone, water vapor are unmixed components of the atmosphere and their concentrations are the function of height, the site elevation effects the relative proportion of the atmospheric constituents. We have measured solar radiation on Jiri Mt. (1,400m) and in Gurye area(115m) at the near same latitude. These values were then compared to obtain their characteristics and to investigate the potential for the solar utilization for both high and low elevated areas. From the experimental results, we concluded that 1) Daily mean horizontal global radiation and normal beam radiation on Mt. Jiri are 9.5%, and 35.3% higher than Gurye area respectively for a clear day. 2) A significant difference in atmospheric clearness index is observed between Mt. Jiri and Gurye areas.

Analysis of Long-wave Radiation Characteristics According to Atmospheric Conditions in Daegu Area During Summer (하절기 대구지역의 대기상태에 따른 장파복사 특징 분석)

  • Baek, Chang-Hyeon;Choi, Dong-Ho;Lee, Bu-Yong;Lee, In-Gyu
    • Journal of the Korean Solar Energy Society
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    • v.38 no.5
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    • pp.1-9
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    • 2018
  • The purpose of this study is to analyze the urban heat island ultimately by analyzing long-wave radiation which is the dominant factor of night minimum temperature formation. We observed during two months with four elements which is long and short wave radiation, temperature, relative humidity. And we analyzed the correlation between the four factors of long-wave radiation, temperature, cloud form, and cloud amount during the summer two months on the night time. Observations were carried out at two sites in Daegu and nearby. The results are as follows. (1) Long-wave radiation change per $1^{\circ}C$ in summer was larger than winter. (2) Long-wave radiation amount is affected by temperature change when the amount of cloud is small. (3) Low cloud was analyzed to have more influence on long-wave radiation than high cloud.

Analysis of Individual Exposure Dose of Workers and Clinical Practice Students in Radiation Management Area (방사선관리구역내의 종사자 및 임상실습 학생의 개인피폭선량 비교 분석)

  • Lee, Joo-Ah
    • The Journal of the Korea Contents Association
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    • v.17 no.11
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    • pp.383-388
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    • 2017
  • The purpose of this study was to compare radiation dose among workers in the radiation zone and to compare the doses of students in clinical practice in the same area to provide basic data on optimization of radiation protection. The subjects were 121 radiation related workers, 36 radiation workers, and 121 students who completed 8 weeks of clinical practice from Jan. 2016 to Dec. The depth and surface dose between the radiation related workers and the radiation workers were the highest with $.7440{\pm}1.676mSv$ and $.7753{\pm}1.730mSv$, respectively, and statistically significant (p<.01). Among the three groups, the depth dose was the highest at $.143{\pm}.136mSv$ for clinical practice students and the highest at surface dose of $.1513{\pm}.139mSv$. The lowest in both cases, The mean difference between the two groups was statistically significant (p<.01). In conclusion, it is necessary to manage thoroughly according to the ALARA(As Low As Reasonably Achievable) principle. Especially, it is necessary to systematically manage the dose of radiation for clinical students who are in the blind spot of radiation safety management.

A study on radiation safety education, knowledge, and practice in using portable intraoral X-ray equipment of dental hygienist's (치과위생사의 이동형 구내방사선 촬영에 관한 방사선 방어 교육, 지식, 수행에 관한 연구)

  • Ryu, Jeong-Min;Kang, Bo-Sun;Kim, Seol-Hee
    • Journal of Korean society of Dental Hygiene
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    • v.17 no.6
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    • pp.1053-1065
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    • 2017
  • Objectives: The purpose of this study is to evaluate radiation safety education, knowledge and practice of dental hygienists in using handheld portable intraoral X-ray equipment and to suggest the need for radiation safety education in using handheld portable intraoral X-ray equipment. Methods: We surveyed 223 dental hygienists from July, 2017 to August in the dental clinics of Daejeon, Seoul and Gyeonggi area. Results: Radiation safety educational experience was higher in a year's career (72.9%), than 3 years experience (32.5%) (p<0.05). 82.7% of dental clinic workers took university education for radiation safety education while 55.6% of dental hospital workers took company training (p<0.05). More than 70% of the subjects did not have experience of radiation safety education about using portable intraoral X-ray. Radiation safety knowledge was highest in a year's career (p<0.05). The cumulative dose, radiation sensitivity, and lead defense knowledge were high in all subjects, but knowledge related to scattering radiation and scattering radiation sources was low. Practice of portable intraoral X-ray safety was significantly lower than knowledge. Conclusions: Knowledge of portable intraoral radiography safety is available, but performance is poor. Even with the small amount of radiation exposure, the risk is perceivable. There is a need to actively utilize the provided radiation protection products. In order to do this, efforts should be made to improve knowledge and performance of radiation safety through not only college education but also postemployment training.