• Biotechnology and Bioprocess Engineering:BBE
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• v.6 no.6
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• pp.402-409
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• 2001

Different bioligands carrying synthetic adsorbents have been reported in the literature for protein separation, We have developed a novel and new approach to obtain high protein ad-sorption capacity utilizing 2-methacrylamidohistidine(MAH) as a bioligand. MAH was synthe-sized by reacting methacrylocholride and histidine, Spherical beads with an average size of 150-200㎛ were obtained by the radical suspension polymerization of MAH and 2-hydrosyethyl-methacrylate(HEMA) conducted in an aqueous dispersion medium. p(HEMA-co-MAH) beads had a specific surface area of 17.6㎡/g . Synthesized MAH monomer was characterized by NMR. p(HEMA-co-MAH) beads were characterized by swelling test, FTIR and elemental analysis. Then Cu(II) ions were incorporated onto the beads and Cu(II) loading was found to be 0.96 mmol/g.These affinity beads with a swelling ration of 65% and containing, 1.6 mmol MAH/g were used in the adsorption/desorption of human serum albumin(HSA) from both aqueous solutions and hu-man serum. The adsorption of HSA onto p(HEM-co-MAH) was low(8.8 mg/g). Cu(II) chelation onto the beads significantly increased the HSA adsorption (56.3 mg/g). The maximum HSA ad-sorption ws observed at pH 8.0 Higher HSA adsorption was observed from human plasma(94.6 mgHSA/g) Adsorption of other serum proteins were obtained as 3.7 mg/g for fibrinogen and 8.5mg/g for γ-globulin. The total protein adsorption was determined as 107.1mg/g. Desorption of HSA was obtained using 0.1 M Tris/HCl buffer containing 0.5 M NaSCN, High desorption rations(up to 98% of the adsorbed HSA) were observed. It was possible to reuse Cu(II) chelated-p(HEMA-co-MAH) beads without significant decreases in the adsorption capacities.

• Journal of the Korean Ceramic Society
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• v.50 no.4
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• pp.263-268
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• 2013

Porous biphasic calcium phosphate scaffolds were fabricated by a freeze-gel casting technique using a tertiary-butyl alcohol (TBA)-based slurry. After sintering, unidirectional macropore channels of scaffolds aligned regularly along the TBA ice growth direction were tailored simultaneously with micropores formed in the outer wall of the pore channels. The crystallinity, micro structure, pore configuration, bulk density, and compressive strength for the scaffolds were investigated with X-ray diffractometery, scanning electron microscopy analysis, a water immersion method, and a universal test machine. The results revealed that the sintered porosity and pore size generally resulted in a high solid loading which resulted in low porosity and small pore size, which relatively increased the higher compressive strength. After being sintered at $1100-1300^{\circ}C$, the scaffolds showed an average porosity and compressive strength in the range 35.1-74.9% and 65.1-3.0 MPa, respectively, according to the processing conditions.

• Steel and Composite Structures
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• v.25 no.1
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• pp.105-116
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• 2017

This paper presents the dynamic stability study of laminated composite plates with different force combinations and aspect ratios. Optimum non-diverging stacking is obtained for certain loading combination and aspect ratio. In addition, the stability force is maximized for a definite operating frequency. A dynamic version of the principle of virtual work for laminated composites is used to obtain force-frequency relation. Since dynamic stiffness governs the divergence or flutter, an efficient optimization method is necessary for the response functional and the relevant constraints. In this way, a model based on the ant colony optimization (ACO) algorithm is proposed to search for the proper stacking. The ACO algorithm is used since it treats with large number of dynamic stability parameters. Governing equations are formulated using classic laminate theory (CLT) and von-Karman plate technique. Load-frequency relations are explicitly obtained for fundamental and secondary flutter modes of simply supported composite plate with arbitrary aspect ratio, stacking and boundary load, which are used in optimization process. Obtained results are compared with the finite element method results for validity and accuracy convince. Results revealed that the optimum stacking with stable dynamic response and maximum critical load is in angle-ply mode with almost near-unidirectional fiber orientations for fundamental flutter mode. In addition, short plates behave better than long plates in combined axial-shear load case regarding stable oscillation. The interaction of uniaxial and shear forces intensifies the instability in long plates than short ones which needs low-angle layup orientations to provide required dynamic stiffness. However, a combination of angle-ply and cross-ply stacking with a near-square aspect ratio is appropriate for the composite plate regarding secondary flutter mode.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.7 no.8
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• pp.1691-1697
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• 2003

The Internet is standing in the spotlight of a new medium of advertisement with explosive growth of market share of electronic commerce, several Internet advertising methods have been implemented. Among them, the banner advertising method is typically being used in the Internet, but the users are not willing to see the banner advertising, moreover that method shows low click rate. Accordingly we propose a new Internet advertising method that makes expose advertising content according to proper text keyword in the article of web pages. During user is reading a article of web page, when user puts mouse pointer over a text keyword, previously specified advertising content is appeared on the web page. The proposed method is based on the keyword advertising, and unlike banner advertising, various shape of images can be applied. Also whole web page could be used for advertising area, and the method does not affect loading delay time of web page.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.459-467
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• 2016

Recently, new open-cut modular construction method, which is built within a 5~7m depth below the road, was proposed for the near-surface transit system to ensure the economic feasibility of underground structures. In this paper, the precast modular construction method was developed for the low-cost and rapid construction of underground structures. For the experiment on the flexural performance of the modular slab connections, a total of eleven specimens were fabricated according to the test variables; section shape, joint type, lap length, and transverse reinforcement. The test results were compared with those of the specimens without loop joints. To verify the performance of the slab connections, the 4-point loading tests of precast RC members with loop joints were conducted. As a result of the test, the flexural performance of the half-depth specimens with a 200mm lap length of loop joints were confirmed to be similar to those of the specimens without joints.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.8 no.3
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• pp.13-22
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• 2012

According to recent research on leak-rate estimates to assess rupture probabilities of nuclear piping which contains a circumferential surface/through-wall cracks due to PWSCC, i.e., xLPR (Extremely Low Probability of Rupture) program, it has been revealed that the use of crack shape with an idealized circumferential through-wall crack during actual crack growth can lead to overestimate of the leak-rate. Thus, for accurate estimation of the leak-rate during crack growth, the more realistic crack shape that can simulate the crack shape transition from surface crack to through-wall crack should be used. In this context, in the present study, the elastic crack opening displacement of slanted circumferential through-wall crack in thick-walled cylinder was proposed based on 3-dimensional elastic finite element fracture mechanics analyses. To propose the elastic crack opening displacement of slanted circumferential through-wall crack in thick-walled cylinder, the geometric variables affecting crack opening displacement, i.e., thickness of cylinder, reference inner crack length and slant crack ratio were systematically varied. In terms of loading conditions, axial tension, global bending moment and internal pressure were considered. The present results can be applied to calculate the leak-rate considering more realistic crack shape transition from surface crack to idealized through-wall crack, and can be expected to enhance current leak-rate estimation scheme, for instance, in xLPR program etc.

• Archives of design research
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• v.17 no.3
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• pp.101-110
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• 2004

The purpose of this study is to draw a distinction between general computer graphics courses and game development ones and to find out making various improvements in game graphics courses. In addition to general hand-drawing skills and computer graphics technology which are essential for the students who major in game graphics; however, the special classes should be required for them to comprehend the work process of game development and to produce the game graphics data. This necessity of the discriminative education is going to be an identification of game development department. Although loading game data onto a game engine and finding out the solution to problems of data is one of the excellent settlement for educating game graphics students, it is not possible to purchase the commercial game engine such as Quake or Lithtech and to analyze the commercial program libraries. For this reason, this research presents the replacement of commercial game engine with VRML97 for the academic purpose and shows what effect upon education will be. It is expected that the VRML97 can be a substitute of the game engine for the effectiveness of game graphics education with more active study and verification of game fields.

• Journal of Satellite, Information and Communications
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• v.5 no.1
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• pp.80-84
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• 2010

Satellite structure should be designed to accommodate and support safely the payload and equipments necessary for its own missions and to secure satellite and payloads from severe laucnch enviroments. The lauch environments imposed on satellites are quasi-static accelerations, aerodynamic loads, acoustic loads and shock loads. To qualify the structure design against low-frequency dyanmic enviromnent, sine vibration test should be performed. During sine vibration test, the notchings are implemented in order to keep the payloads and equipments from excessive loading at their own main modes. This paper deals with sine test prediction, sine vibration test results, comparison of predicted values and tested values, and verification of Finite Element Model.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.8 no.2
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• pp.143-150
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• 2010

Vitrification technology has been gradually recognized as one of effective solidification methods for concentrated boric acid wastes generated in PWR. Vitrification for low- and intermediate-level radioactive wastes has a large volume reduction and good durability for the final products. A feasibility study for the vitrification of concentrated boric acid wastes has been performed with developing the pre-treatment methods of powdered wastes, glass compositions using glass formulation and demonstration test. The pre-treatment method is pelletizing the powder type for stable feeding within cold crucible melter. The glass compositions should be developed considering molten glass are related with wastes reduction. High contents of sodium and boron within borate wastes give influence to waste loading. A variety of factors obtained from the demonstration test are reviewed, which is wastes feeding rate, off-gas characteristics on stack and glass characteristics of final products such as durability for implementing the wastes disposal requirement. The aim of this paper is to present the feasibility of vitrification and review the solidification method for concentrated boric acid wastes and obtain the physicochemical characteristics of solidified glass.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.14 no.3
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• pp.279-287
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• 2016

Korea Radioactive Waste Agency (KORAD) began to operate the low and intermediate level radioactive waste disposal facility in Gyeongju and to transport the radioactive waste containing radioactive isotopes from Daejeon to the disposal facility for the first time at 2015. For this radioactive waste transportation, in this study, radiological impact assessment is carried out for workers and public. The dose rate to workers and public during the transportation is estimated with consideration of the transportation scenarios and is compared with the Korean regulatory limit. The sensitivity analysis is carried out by considering both the variation of release ratios of the radioactive isotopes from the waste and the variation of the distances between the radioactive waste drum and worker during loading and unloading of radioactive waste. As for all the transportation scenarios, radiological impacts for workers and public have met the regulatory limits.