• 대한의용생체공학회:의공학회지
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• 제30권1호
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• pp.18-22
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• 2009

Laser has been widely used in various fields of medicine. Recently, noninvasive low-level laser therapeutic medical devices have been introduced in market. However, low-level laser cannot deliver enough photon density to expect positive therapeutic results in deep tissue layer due to the light scattering property in tissue. In order to overcome the limitation, this study was aimed to develop a negative pressure applied low-level laser probe to optimize laser transmission pattern and therefore, to improve photon density in soft tissue. In order to evaluate the possibility of clinical application of the developed laser probe, ex-vivo experiments were performed with porcine skin samples and laser transmissions were quantitatively measured as a function of tissue compression. The laser probe has an air suction hole to apply negative pressure to skin, a transparent plastic body to observe variations of tissue, and a small metallic optical fiber guide to support the optical fiber when negative pressure was applied. By applying negative pressure to the laser probe, the porcine skin under the metallic optical fiber guide is compressed down and, at the same time, low-level laser is emitted into the skin. Finally, the diffusion images of laser in the sample were acquired by a CCD camera and analyzed. Compared to the peak intensity without the compression, the peak intensity of laser increased about $2{\sim}2.5$ times and FWHM decreased about $1.67{\sim}2.85$ times. In addition, the laser peak intensity was positively and linearly increased as a function of compression. In conclusion, we verified that the developed low-level laser probe can control the photon density in tissue by applying compression, and therefore, its potential for clinical applications.

• Journal of Korean Dental Science
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• 제2권1호
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• pp.42-47
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• 2009

Objective : The purpose of this study was to evaluate the effects of low level lasers on bone healing and new bone formation around titanium dental implants in canine models. 18 oxidized surface treated implants and a Dens-bio laser were used. Study design : Low level lasers were irradiated with a total of 8J for 4 minutes by pulse wave type and 1 minute by continuous type. For the experimental group, a low level laser was used to irradiate the first premolar implant's insertion area at the time of insertion, a low level laser was used to irradiate the second premolar implant's insertion area daily for one week after implant insertion, and a low level laser was used to irradiate the third molar implant's insertion area daily for 2 weeks postoperatively. At the conclusion of the study, sacrificed tissue sections were made from investing tissue and observed under an optical microscope. Results : The rate of new bone formation around the implant showed no significant difference between the control group and the experimental group. New bone formation rates of the control and experimental group 2 weeks following implant placement were higher than that of immediately after implant placement and 1 week after implant placement. Conclusions : Based on these results, a low-level laser showed no statistically significant increase in bone formation following implant placement.

• 대한한방내과학회지
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• 제36권4호
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• pp.561-569
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• 2015

Objectives The purpose of this study was to improve the knowledge of the low-level laser therapy (LLLT) field and to review research reports on LLLT to understand the current situation with respect to the clinical indication and current research trends.Methods A survey was carried out on the subject of low-level laser therapy to September 2012, using the PubMed search engine. Selected literature was checked by two reviewers and was classified according to the International Classification of Diseases 10th (ICD-10) over 10 years.Results We selected 469 studies in total, of which 142 were case reports, 118 were case-controlled trials, and 209 were randomized controlled trials of LLLT. According to the ICD-10 classification of diseases, the K code and M code being the most common, 399 studies have been published in the last 10 years. This shows that the study and clinical indications of low-level laser therapy have rapidly increased over the past 10 years.Conclusions Low-level laser therapy has been used most frequently with respect to dentistry and pain and musculoskeletal disorders. Recently, interest in and research into LLLT has increased for various diseases. With the establishment of standard conditions for low-level laser therapy, supported by aggressive clinical utilization and systematic clinical research, LLLT will be a very useful treatment and a useful alternative method in many medical fields.

• Asian-Australasian Journal of Animal Sciences
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• 제31권8호
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• pp.1285-1290
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• 2018

Objective: This study shows the effects of dietary fiber levels on cecal microbiota composition in geese at day 70 according to pyrosequencing of the 16S ribosomal RNA gene. Methods: A total of 468 1-day-old healthy male Yangzhou goslings with similar body weight were randomly divided into 3 groups with 6 replicates per group and 26 geese per replicate. Geese were fed diets with fiber levels of 2.5% (low fiber level diet, Group I) and 6.1% (Group III) during days 1-70, respectively, or 4.3% for days 1-28 and 6.1% for days 29-70 (Group II). Results: Low fiber level diet decreased body weight, average daily gain during, increased lower feed conversation rate of geese during day 1 to 70 (p<0.05). Low fiber level diet decreased the total operational taxonomic units, Chao1 index and Shannon index, whereas increased the Simpson index of cecal microbiota in geese at day 70. Low fiber level diet decreased the relative abundance of Bacteroidetes, Firmicutes, Bacteroides, and Paraprevotella in cecum of geese at day 70. The similarity of cecal microbiota between low fiber level diet group and other groups was smaller. Conclusion: This study indicates that the low fiber level diet decreased diversity of microbiota, and relative abundance of some beneficial microbiota in cecum of geese at day 70, implying that the low fiber level diet has negative influence on performance by altering the diversity and population of cecal microbiota in geese.

• 한국항공운항학회지
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• 제28권4호
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• pp.1-11
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• 2020

In order to diagnose low-level turbulence in Korea, diagnostic indices of low-level turbulence were calculated from Aug 2016 to Jul 2019 using a Korea Meteorological Administration Post Precessing (KMAPP) developed by the National Institute Meteorological Sciences (NIMS), and the indices were evaluated using Aircaft Meteorological Data Relay (AMDAR). In the mean horizontal distribution of diagnostic indices calculated, severe turbulence was simulated along major domestic mountains, including near the Taebaek Mountains, the Sobaek Mountains and Hallasan Mountain on Jeju Island due to geographical factors. Later, detection performance was evaluated by calculating the KMAPP Low-Level Turbulencd index (KLT) on combined index, using AUC value of Individual diagnostic indices as a weight. The result showed that the AUC value of KLT was 0.73, and the detection performance was improved (0.02-0.13) when the index was combined. Also, when looking for the AMDAR data is divided into years, seasons, and altitudes, up to 0.94 AUC values were found in winter (DJF) and the surface (surface-1,000ft). By using high-resolution numerical data reflecting detailed terrain data, local turbulence distribution was well demonstrated and high detection performance was shown at low-level.

• Clinical and Experimental Reproductive Medicine
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• 제17권1호
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• pp.65-70
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• 1990

Clinical effects of intramuscular injection of 250mg testosterone cypionate every 2-3 weeks were investigated in 15 impotent patients with low or low normal serum testosterone level (Hypo-gonadotrophic hypogonadism was excluded). The results were obtained as follows. 1. Among 15 patients, 7(46.7%) showed markedly improved potency, 6(40%) partially improved potency and 2(13.7%) no improvement of potency. There was no correlation between effec-tiveness of testosterone replacement and age, testicular size, serum testosterone level or LH, FSH level. 2. Among 12 patients who had showed improved potency, 8(66.7%) complained of redeveloped decrease in potency during testosterone replacement. In conclusion, testosterone cypionate for treatment of the impotent patients with low or low normal serum testosterone level was effective, but further studies are necessary to investigate cause of redeveloped decrease in potency during testosterone replacement.

• 복식
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• 제66권2호
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• pp.1-14
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• 2016

This study was intended to investigate the influences that consumer's price sensitivity, bundle discount type, and price level of the male cosmetics have on consumer attitude. The design of this research was comprised of $2{\times}2{\times}2$ mixed design studies. The first element was high price sensitivity vs. low sensitivity, the second element was the bundle discount type (mixed leader vs. mixed-joint), and the third element was the price level of male cosmetics (high-price brand vs. low-price brand). The results of this study showed that price sensitivity, bundle discount type and price level of male cosmetic had a statistically significant interaction effect on the consumer's quality perception. The quality perception of low-cost brands for high price sensitivity/mixed-joint bundle group was low. The quality perception of low-cost brands for mixed-leader bundled groups did not change significantly even when the price sensitivity became higher. However, it can be seen as the same result that the overall value is higher when suggested the price information in Mixed-leader bundle than Mixed-joint bundle. In particular, this study suggests that price information should be presented in mixed-leader bundles for high price sensitivity and low cast brands.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.1039-1043
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• 2005

Despite the many significant advances made in robot architecture, the basic approaches are deliberative and reactive methods. They are quite different in recognizing outer environment and inner operating mechanism. For this reason, they have almost opposite characteristics. Later, researchers integrate these two approaches into hybrid architecture. In such architecture, Reactive module also called low-level motion control module have advantage in real-time reacting and sensing outer environment; Deliberative module also called high-level task planning module is good at planning task using world knowledge, reasoning and intelligent computing. This paper presents a framework of the integrated planning and control for mobile robot navigation. Unlike the existing hybrid architecture, it learns topological map from the world map by using MST (Minimum Spanning Tree)-based SOFM (Self-Organizing Feature Map) algorithm. High-level planning module plans simple tasks to low-level control module and low-level control module feedbacks the environment information to high-level planning module. This method allows for a tight integration between high-level and low-level modules, which provide real-time performance and strong adaptability and reactivity to outer environment and its unforeseen changes. This proposed framework is verified by simulation.

• 한국수자원학회논문집
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• 제33권5호
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• pp.635-645
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• 2000

감조하천에서는 수위, 유량과 조석이 상호관련이 있다. 특히 저수위에서 조석의 영향을 감안하지 않은 수위-유량관계는 부정확하다. 본 논문에서는 수위와 조위의 수면차를 변수로 하여 감조하천에서의 유량을 계산할 수 있도록 하였다. 이를 위해 태화강 감조부에 위치한 울산수위관측소 지점의 저수위 유량을 수위 및 수위와 조위의 수면차로 나타내는 다중회귀식을 개발하였으며, 기존의 수위-유량곡선식과 비교한 결과 우수한 적용성을 확인하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제16권2호
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• pp.261-265
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• 2003

This study was performed to determine whether transglutaminase (Aciva-TG, TGase) can be used to reduce the salt level in low-fat sausages and to replace emulsified meats (10%) for the manufacture of restructured meat products (RMP). Pork hams and loins were collected from a local retail market in Gwangju, Korea and used for the manufacture of sausages and RMPs, respectively. TGase at the level of 0.1% can permit the reduction of the salt level from 1.5% to 1.0% in low-fat comminuted sausages without any quality defects, however a crumbly texture was found if the salt level was reduced below 1.0% even though it combined with certain amounts of TGase. No differences in chemical composition and physical properties were observed (p>0.05) among treatments. Approximately 0.3% of TGase can replace 10% emulsified meats, which are normally used for improvement of binding capacity to manufacture RMPs, without quality defects. This study suggests that TGase could be used for the manufacture of low-fat, low-salt functional meat products for the improvement of textural characteristics and binding capacity without adverse effects.