• Title/Summary/Keyword: low dose X-ray

Search Result 188, Processing Time 0.042 seconds

DNA Damage by X-ray and Low Energy Electron Beam Irradiation (X선과 저에너지 전자선에 의한 DNA 손상)

  • Park, Yeun-Soo;Noh, Hyung-Ah;Cho, Hyuck;Dumont, Ariane;Ptasinska, Sylwia;Bass, Andrew D.;Sanche, Leon
    • Journal of Radiation Protection and Research
    • /
    • v.33 no.2
    • /
    • pp.53-59
    • /
    • 2008
  • We observed DNA damages as a function of mean absorbed dose to identify the indirect effect of high-energy radiation such as x-ray. Monolayer films of lyophilized pGEM-3Zf(-) plasmid DNA deposited on tantalum foils were exposed to Al $K{\alpha}$ X-ray (1.5 keV) for 0, 3, 7 and 10 min, respectively, in a condition of ultrahigh vacuum state. We compared DNA damages by X-ray irradiation with those by 3 eV electron irradiation. X-ray photons produced low-energy electrons (mainly below 20 eV) from the tantalum foils and DNA damage was induced chiefly by these electrons. For electron beam irradiation, DNA damage was directly caused by 3 eV electrons. Irradiated DNA was analyzed by agarose gel electrophoresis and quantified by ImagaQuant program. The quantities of remained supercoiled DNA after irradiation were linearly decreased as a function of mean absorbed dose. On the other hand, the yields of nicked circular (single strand break, SSB) and interduplex crosslinked form 1 DNA were linearly increased as a function of mean absorbed dose. From this study, it was confirmed that DNA damage was also induced by low energy electrons ($0{\sim}10\;eV$) even below threshold energies for the ionization of DNA.

Photon-Counting Detector CT: Key Points Radiologists Should Know

  • Andrea Esquivel;Andrea Ferrero;Achille Mileto;Francis Baffour;Kelly Horst;Prabhakar Shantha Rajiah;Akitoshi Inoue;Shuai Leng;Cynthia McCollough;Joel G. Fletcher
    • Korean Journal of Radiology
    • /
    • v.23 no.9
    • /
    • pp.854-865
    • /
    • 2022
  • Photon-counting detector (PCD) CT is a new CT technology utilizing a direct conversion X-ray detector, where incident X-ray photon energies are directly recorded as electronical signals. The design of the photon-counting detector itself facilitates improvements in spatial resolution (via smaller detector pixel design) and iodine signal (via count weighting) while still permitting multi-energy imaging. PCD-CT can eliminate electronic noise and reduce artifacts due to the use of energy thresholds. Improved dose efficiency is important for low dose CT and pediatric imaging. The ultra-high spatial resolution of PCD-CT design permits lower dose scanning for all body regions and is particularly helpful in identifying important imaging findings in thoracic and musculoskeletal CT. Improved iodine signal may be helpful for low contrast tasks in abdominal imaging. Virtual monoenergetic images and material classification will assist with numerous diagnostic tasks in abdominal, musculoskeletal, and cardiovascular imaging. Dual-source PCD-CT permits multi-energy CT images of the heart and coronary arteries at high temporal resolution. In this special review article, we review the clinical benefits of this technology across a wide variety of radiological subspecialties.

A Study on Overexposure Rate according to Overdensity in Chest X-ray Radiography(II) (흉부촬영에서 overdensity에 따른 overexposure rate를 아는 방법(II))

  • Kim, Jung-Min;Huo, Joon;Hayashi, Taro
    • Journal of radiological science and technology
    • /
    • v.23 no.1
    • /
    • pp.13-19
    • /
    • 2000
  • We have presented with the "A study on overexposure rate according to over-density in chest X-ray radiography(I)" last year. In this report, We could calculate the entrance skin dose from chest X-ray film density the formula $I_0=Ix/e^{-{\mu}x}{\times}mG$, (mG is Bucky factor) was used to deliver the skin dose. At that time, There was two problems that the Bucky factor from maker was not equal to field experience and the field size influenced on the Attenuation Rate. The experiment of Bucky factor was done from film method and retried the Attenuation Rate of Acryle phantom according to Good & Poor geometry. As the results, The Bucky factor from maker higher than in this experiments $30{\sim}40%$. The Attenuation Rate in good geometric condition brings about a little alteration compare with poor geometric condition. In the field experiment, we could get the chest image with very low entrance skin radiation dose $29.3{\mu}Sv$, especially with air gap methode, the entrance skin dose was detected $10{\mu}Sv$.

  • PDF

A Comparison of Dose in Changed Technique Factor Using X-ray Imaging System (X-선 장치의 기술적 인자의 변화에 따른 선량 비교 평가)

  • Han, Dong-Kyoon;Ko, Shin-Gwan;Seon, Jong-Ryul;Yoon, Seok-Hwan;Jung, Jae-Eun
    • Korean Journal of Digital Imaging in Medicine
    • /
    • v.11 no.2
    • /
    • pp.101-107
    • /
    • 2009
  • With the recent development of diagnosis using radiation and increasing demand of the medical treatment, we need to minimize radiation exposure dose. So, This is the method which reduce patient dose by measuring surface dose of radiographic change factor and by comparing theoretical and actual dose, when we take an X-ray which is generally used. By changing the factor of kV, mAs, FSD, whose range is 60 to 120 kV, 20 to 100 mAs, 80 to 180 cm, we compared theoretical surface dose with actual surface dose calculated by the simple calculation program, Bit system, and NDD-M method As a result, when kV and mAs were higher, theoretical surface dose and actual surface dose were more increased. but the higher FSD was, the more decreased surface dose was. According to this, the error were measured about 0.1 to 0.2 mGy in low dose part and about 0.7 to 1.5 mGy in high dose part. Therefore, this shows that theoretical surface dose calculation method is more correct in low dose part than in high dose part. In conclusion, we will have to make constant efforts which can reduce patient and radiographer's exposure dose, studying methods which can predict patient's radiation exposure dose more exactly.

  • PDF

Development of DAP(Dose Area Product) for Radiation Evaluation of Medical and Industrial X-ray generator (의료 및 산업용 X-선 발생장치의 선량평가를 위한 면적선량계(DAP) 개발)

  • Kwak, Dong-Hoon;Lee, Sang-Heon;Lee, Seung-Ho
    • Journal of IKEEE
    • /
    • v.22 no.2
    • /
    • pp.495-498
    • /
    • 2018
  • In this paper, we propose an DAP system for dose evaluation of medical and industrial X-ray generator. Based on the DAP measurement technique using the Ion-Chamber, the proposed system can clearly measure the exposure radiation dose generated by the diagnostic X-ray apparatus. The hardware part of the DAP measures the amount of charge in the air that is captured by an X-ray. The high-speed processing algorithm part for cumulative radiation dose measurement through microcurrent measures the amount of charge captured by X-ray at a low implementation cost (power) with no input loss. The wired/wireless transmission/reception protocol part synchronized with the operation of the X-ray generator improves communication speed. The PC-based control program part for interlocking and aging measures the amount of X-ray generated in real time and enables measurement graphs and numerical value monitoring through PC GUI. As a result of evaluating the performance of the proposed system in an accredited testing laboratory, the measured values using DAP increased linearly in each energy band (30, 60, 100, 150 kV). In addition, since the standard deviation of the measured value at the point of 4 division was ${\pm}1.25%$, it was confirmed that the DAP showed uniform measurements regardless of location. It was confirmed that the normal operation was not less than ${\pm}4.2%$ of the international standard.

Development of a Cantilevered Patient Table Considering X-ray Transparency (X-선 투과특성을 고려한 외주형 수술용 테이블 개발)

  • Won B.H.;Chun K.J.
    • Proceedings of the Korean Society of Precision Engineering Conference
    • /
    • 2006.05a
    • /
    • pp.189-190
    • /
    • 2006
  • A patient table considering x-ray transparency, mechanical safety and compact multi-axis moving mechanism has been developed. The goal of medical imaging technology is to keep radiation exposure of patients during x-raying to a minimum. In order to obtain clear pictures at low dose, however, the x-ray table which supports the patient must be sufficiently permeable to radiation to allow good image resolution. The table top is made of low density foam for x-ray transparent effective area and structural aluminum plate to connect moving mechanism under the table, covered with thin carbon fiber. This sandwich construction is very rigid and lightweight, so the table top can handle relatively heavy load comparing to its cantilevered structure which is unavoidable as long as cooperate with C-arm radiography. To verify the design results finite element static analysis and experimental tests have been done. According to the verification the results well satisfy certification guide lines as a medical device.

  • PDF

A Study on Feasibility of Total Variation Algorithm in Skull Image using Various X-ray Exposure Parameters (다양한 X-ray 촬영조건을 이용하여 획득한 skull 영상에서의 Total Variation 알고리즘의 가능성 연구)

  • Park, Sung-Woo;Lee, Jong-In;Lee, Youngjin
    • Journal of the Korean Society of Radiology
    • /
    • v.13 no.5
    • /
    • pp.765-771
    • /
    • 2019
  • Noise in skull X-ray imaging is inevitable, which reduces imaging quality and diagnostic accuracy and increases errors due to the nature of digital imaging devices. Increasing the dose can attenuate noise, but that could lead to big problems with higher exposure dose received by patients. Thus, noise reduction algorithms are actively being studied at low doses to solve dose problems and reduce noise at the same time. Wiener filter and median filter have been widely used, with the disadvantages of poor noise reduction efficiency and loss of much information about imaging boundary. The purpose of this study is to apply total variation (TV) algorithm to skull X-ray imaging that can compensate for the problems of previous noise reduction efficiency to assess quantitatively and compare them. For this study, skull X-ray imaging is obtained using various kVp and mAs using the skull phantom using the X-ray device of Siemens. In addition, contrast to noise ratio (CNR) and coefficient of variation (COV) are compared and measured when noisy image, median filter, Wiener filter and TV algorithm were applied to each phantom imaging. Experiments showed that when TV algorithms were applied, CNR and COV characteristics were excellent under all conditions. In conclusion, we've been able to see if we can use TV algorithm to improve image quality and CNR could be seen to increase due to the decrease in noise as the amount of increased mAs. On the other hand, COV decreased as the amount of increased mAs, and when kVp increased, noise was reduced and the transmittance was increased, so COV was reduced.

Calculation of Effective Dose on Domestic Chest PA X-ray Examinations (국내 흉부 X-선 검사에 따른 유효선량 계산)

  • Choi, Seokyoon
    • Journal of the Korean Society of Radiology
    • /
    • v.12 no.7
    • /
    • pp.827-832
    • /
    • 2018
  • Research on effective dose analysis of actual conditions of use based on large data is scarce. In this study, the exposure conditions of Chest X-Ray examinations used by 324 medical institutions in Korea were calculated and evaluated using computer simulations. As a result of the experiment, the effective dose in the low energy parameter bands was 0.024 mSv, followed by spleen, adrenal glands, and lung. The effective dose in the high-energy exposure parameter band was 0.123 mSv, followed by height, spleen and adrenal glands. The effective dose was 0.017 mSv when the optimal conditions considered the quality and exposure proposed in Park's study were used. The results of the study will be a reference for chest X-rays and will help reduce patient exposure.

Enhancement of Image Quality Using Detector Filter (검출기 필터를 이용한 화질의 향상)

  • Lim, Jong-Nam;Kim, Hyung-Tae;Kim, Min-Hye;Chon, Kwon Su
    • Journal of the Korean Society of Radiology
    • /
    • v.10 no.6
    • /
    • pp.451-456
    • /
    • 2016
  • Radiation dose to patient is unavoidable when diagnosis is carried out using X-ray. Radiation diagnosis using dual energy X-ray was examined to verify the possibility of medical applications by SNR and image scoring. The dual energy X-ray was realized by combining together two image plates and filter of 0.5 mm thick Cu or Al. Under one X-ray exposure, contrast enhanced image was obtained using two images of image plates. The enhanced image showed higher SNR and image score compared to the first image which was the image recorded with the first image plate. The dual energy X-ray technique would be a very useful method for obtaining higher SNR image and for realizing very low dose, and could be applied to medical applications.

Development of X-ray Detector using Liquid Crystal with Front Light (전면광원(Front Light)을 적용한 액정 X선 검출기 개발)

  • Rho, Bong Gyu;Baek, Sam Hak;Kang, Seok Jun;Lee, Jong Mo;Bae, Byung Seong
    • Journal of the Korean Society of Radiology
    • /
    • v.13 no.6
    • /
    • pp.831-840
    • /
    • 2019
  • The X-ray detector by liquid crystal with front light was proposed and verified by a X-ray image. The proposed detector utilizes the visible light instead of the electric signal by transistor. Therefore, it shows low noise and can be fabricated at low cost. The liquid crystal detector uses the orientation change of the liquid crystal molecule by conductivity change of the photoconductive layer. We can get the X-ray image from the transmitted light through the liquid crystal. The X-ray dose was calibrated from the measured transmittance of the visible light after comparison to the reference transmittance curve of the liquid crystal. The amorphous Se was used for photo con ducting layer and parylene was used for the liquid crystal alignment instead of the conventional alignment layer which needs high-temperature process over 200℃. The proposed X-ray detector can decrease the X-ray dose by high sensitivity which was verified by simulation. After the fabrication of the X-ray detector, the X-ray image was obtained as a function of the bias voltage to the liquid crystal. 10 lines/mm resolution was obtained from the line pattern and we will apply it to the 17inch diagonal liquid crystal X-ray detector with 3π retardation.