• 한국지진공학회:학술대회논문집
• /
• 한국지진공학회 2000년도 추계 학술발표회 논문집 Proceedings of EESK Conference-Fall 2000
• /
• pp.440-447
• /
• 2000

In order to evaluate the cost effectiveness of seismic isolation for bridges in low and moderate seismic region, a method of calculation minimum life-cycle cost of seismic-isolated bridges under specific acceleration level and soil condition is developed. Input ground motion is modeled as spectral density function compatible with response spectrum for combination of acceleration coefficient and site coefficient. Failure probability is calculated by spectrum analysis based on random vibration theories to simplify repetitive calculations in the minimization procedure. Ductility of piers and its effects on cost effectiveness are considered by stochastic linearization method. Cost function and cost effectiveness index are defined by taking into consideration the characteristics of seismic isolated bridges. Limit states for calculation of failure probability are defined on superstructure, isolator and pier, respectively. The results of example design and analysis show that seismic isolation is more cost-effective in low and moderate seismic region than in high seismic region.

• Journal of Korean Medical Science
• /
• 제33권46호
• /
• pp.304.1-304.7
• /
• 2018

Background: The Republic of Korea has a very low prevalence of human immunodeficiency virus (HIV) infection, but the number of new HIV diagnoses has steadily risen, strongly indicating a large number of undetected HIV infections. Thus, it is important for Korean public health authorities to adopt and encourage cost-effective HIV detection tools, such as rapid HIV screening tests. In this study, we aimed to evaluate the cost-effectiveness of enzyme-linked immunosorbent assays (ELISA) and rapid tests in a public health center (PHC) setting. Methods: We developed a decision analytic model to assess the per-examinee cost and the cost-effectiveness of identifying HIV patients in a PHC setting using two HIV testing strategies: conventional HIV screening by ELISA versus rapid HIV testing. Analysis was performed in two scenarios: HIV testing in an average-risk population and in a high-risk population. Results: Compared to the ELISA, the rapid test was cost-saving and cost-effective. The per-examinee cost was USD 1.61 with rapid testing versus USD 3.38 with ELISA in an average-risk population, and USD 4.77 with rapid testing versus USD 7.62 with ELISA in a high-risk population. The cost of identifying a previously undiagnosed HIV case was USD 26,974 with rapid testing versus USD 42,237 with ELISA in an average-risk population, and USD 153 with rapid testing versus USD 183 with ELISA in a high-risk population. Conclusion: Rapid testing would be more cost-effective than using conventional ELISA testing for identifying previously undiagnosed HIV-infected cases in Korea, a country with extremely low HIV prevalence.

• 보건행정학회지
• /
• 제9권3호
• /
• pp.70-94
• /
• 1999

This paper was performed for a cost-effectiveness analysis of pharmacologic treatment of hypercholesterolemia. Agents modeled were cholestyramine, gemfibrozil. bezafibrate, lovastatin, pravastatin, simvastatin. Pharmacologic effectiveness was estimated by regression from reported clinical trials. Pharmacologic effects were expressed as the percent change of blood cholesterol level. Cost estimates included patients' travel expenses and time loss as well as resource consumption in the health care sector. Bezafibrate was the most efficient agent for reducing total cholesterol levels, having an cost over 1 year of ￦31.400 per percent reduction in total cholesterol. Simvastatin (10mg/d) was also efficient(￦33,100 per percent reduction). Chole styramine(8g/d) was least efficient at ￦90,200. For low-density lipoprotein cholesterol. simvastatin(10mg/d) was most efficient, at ￦23,200 per percent reduction, followed by lovastatin(20mg/d) at ￦28,000. Gemfibrozil was least efficient at ￦77,800 per percent reduction. For high-density lipoprotein cholesterol. bezafibrate(400mg/d) was most efficient at ￦39,300 per percent increase of high-density lipoprotein cholesterol. Cholestyramine was least efficient at ￦514,700. Analyses combining low-density lipoprotein cholesterol and high-density cholesterol effects suggest that bezafibrate(600mg/d) and simvastatin (10mg/d) were most efficient for reducing cardiovascular risk. The cost-effectiveness analysis results show that both simvastatin and bezafibrate could be efficient treatment. Simvastatin provide more effective treatment at higher cost, whereas bezafibrate is more cost-effective, as it may be less effective, at lower cost. Therefore, clinicians should choose reasonable treatment according to the patient's needs This pharmacoeconimc analysis will provide a guideline for efficient pharmacologic treatment and also be reference data for pricing new drugs.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1997년도 하계학술대회 논문집 F
• /
• pp.2072-2074
• /
• 1997

A new low-cost high power factor correction circuit for electronic ballasts is proposed. The proposed circuit provides good power factor correction, low current harmonic distortion and cost-effectiveness. The prototype meets the IEC555-2 requirements satisfactorily with nearly unity power factor.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권12호
• /
• pp.7701-7706
• /
• 2013

Background: In a prospective cohort study of antiemetic therapy conducted in Malaysia, a total of 94 patients received low emetogenic chemotherapy (LEC) with or without granisetron injections as the primary prophylaxis for chemotherapy-induced nausea and vomiting (CINV). This study is a retrospective cost analysis of two antiemetic regimens from the payer perspective. Materials and Methods: This cost evaluation refers to 2011, the year in which the observation was conducted. Direct costs incurred by hospitals including the drug acquisition, materials and time spent for clinical activities from prescribing to dispensing of home medications were evaluated (MYR 1=$0.32 USD). As reported to be significantly different between two regimens (96.1% vs 81.0%; p=0.017), the complete response rate of acute emesis which was defined as a patient successfully treated without any emesis episode within 24 hours after LEC was used as the main indicator for effectiveness. Results: Antiemetic drug acquisition cost per patient was 40.7 times higher for the granisetron-based regimen than for the standard regimen (MYR 64.3 vs 1.58). When both the costs for materials and clinical activities were included, the total cost per patient was 8.68 times higher for the granisetron-based regimen (MYR 73.5 vs 8.47). Considering the complete response rates, the mean cost per successfully treated patient in granisetron group was 7.31 times higher (MYR 76.5 vs 10.5). The incremental cost-effectiveness ratio (ICER) with granisetron-based regimen, relative to the standard regimen, was MYR 430.7. It was found to be most sensitive to the change of antiemetic effects of granisetron-based regimen. Conclusions: While providing a better efficacy in acute emesis control, the low incidence of acute emesis and high ICER makes use of granisetron as primary prophylaxis in LEC controversial.

• 한국지진공학회:학술대회논문집
• /
• 한국지진공학회 2001년도 춘계학술대회 논문집
• /
• pp.387-393
• /
• 2001

Installing vibration control devices in the structure rises as a solution instead of increasing structural strength considering construction cost. Especially, viscoelastic dampers show excellent vibration control performance at low cost and are easy to install in existing structures compared with other control devices. Therefore, cost-effectiveness of structure with viscoelastic dampers needs to be evaluated. Previous cost-effectiveness evaluation method for the seismically isolated structure(Koh et al., 1999;2000)is applied on the building structure with viscoelastic dampers, which combines optimal design and cost-effectiveness evaluation for seismically isolated structures based on minimum life-cycle cost concept. Input ground motion is modeled in the form of spectral density function to take into account acceleration and site coefficients. Damping of the viscoelastic damper is considered by modal strain energy method. Stiffness of shear building and shear area of viscoelastic damper are adopted as design variables for optimization. For the estimation of failure probability, transfer function of the structure with viscoelastic damper for spectral analysis is derived from the equation of motion. Results reveal that cost-effectiveness of the structure with viscoelastic dampers is relatively high in how seismic region and stiff soil condition.

• 한국안전학회지
• /
• 제27권5호
• /
• pp.95-98
• /
• 2012

There are many high-rise apartment building construction in Korea. There was an accident to pass through worker head by rebar dropped from height place. Therefore, low cost-high effectiveness method to prevent this type of accident should be revised and applied into the construction site. This study is to find out which method could be effectively applied to a site with low cost. Practical field test at 4th floor, 10th floor of apartment building site using re-bar diameter D10, D13, D16, D19, D22 with a length of 1 m, 1.5 m, 2 m, 2.5 m, 3 m which are common by used in a site. The test has also been done with a cover of styrofoam thickness 4.5 cm and thickness 9cm on field drop preventing net. One sheet of styrofoam thickness 45 mm has approximately two times stronger than only prevention net, It is found. Also, Two sheets have approximately two times stronger than one sheet of it.

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
• /
• 제53권3호
• /
• pp.180-187
• /
• 2004

A conventional power supply of a microwave oven has a 60Hz transformer and high voltage capacitor(HVC). Though it is very simple and has low cost, it has several problems such as large size, heavy weight and low efficiency To improve these problems, various high frequency inverter type power supply have been investigated and developed in recent years. But these cost is higher than the conventional one due to additional control circuit, fast switching devces. In this paper, a novel pulse power supply for microwave oven using high frequency transformer embedded HVC(High Voltage Capacitor) is proposed for down-sizing, cost reduction and efficient improvement. To verify the effectiveness of the proposed transformer, an equivalent circuit of transformer embedded HVC is derived and it's characteristic is described. And the validity of the proposed pulse power supply embedded HVC-high frequency transformer is shown by simulations and experiments accroding to various operating conditions.

• Journal of Power Electronics
• /
• 제12권3호
• /
• pp.487-494
• /
• 2012

A new low cost high power density photovoltaic power conditioning system (PV PCS) with an energy storage system is proposed in this paper. Its high power density and cost effectiveness can be achieved through the unification of the maximum power point tracker and the battery charger/discharger. Despite the reduced power stage, the proposed system can achieve the same performance in terms of maximum power point tracking and battery charging/discharging as the conventional system. When a utility power failure happens, the proposed system cannot perform maximum power point tracking at the UPS mode. However, the predetermined battery voltage near the maximum power point of the PV array can effectively generate a reasonable PV power even at the UPS mode. Therefore, it features a simpler structure, less mass, lower cost, and fewer devices. Finally, to confirm the operation, validity, and features of the proposed system, a theoretical analysis and experimental results from a single phase AC 220Vrms/1.5kW prototype are presented.

• 전력전자학회논문지
• /
• 제20권2호
• /
• pp.122-129
• /
• 2015

In this study, we propose a low voltage stress and cost-effective light emitting diode (LED) driver capable of multi-channel current balancing. Conventional LED drivers require as many boost converters as the number of LED channels, whereas the proposed LED driver requires only one buck converter and several balancing capacitors instead of several expensive boost converters. Additionally, while the components of the boost converter have high voltage stress and depend on the LED driving voltage, components of the proposed driver have about one-half of the voltage stress across all components. The proposed driver exhibits high reliability and cost effectiveness because it only uses few DC blocking capacitors with no additional active devices to balance the current of multi-channel LEDs. The proposed driver exhibits high reliability and cost effectiveness. The validity of the proposed driver is confirmed through a theoretical analysis. An explanation of the design considerations and experimental results were obtained using a prototype applicable to a 46" LED-TV.