• 제목/요약/키워드: longitudinal studies

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동맥 전단부의 역학적분석을 위한 새로운 실험적 방법 (A New Experimental Method of Mechanical Analysis for Arterial Cross-Section Research)

  • 황민철;신정욱
    • 대한의용생체공학회:의공학회지
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    • 제16권2호
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    • pp.149-156
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    • 1995
  • 동맥전단부를 연구할수있는 새로운 실험방법과 기계역학적 분석방법을 제시하였다. 지금까지동맥역학적 연구는 대부분이 동맥의 길이방향과 원주방향에 대한것이 이였다. 두께방향의 변형은 포아손비라든지 비압축성가정으로 이론적으로 결정되었다. 또한 두께에 걸친 변형의 변화도 무시되었다. 그러나 병리학적인 의미에서 동맥의 두께에 걸친 변형도와 변형의 분포는 중요한 의미를 가진다. 그러므로 본연구에서 제안된 실험방법과 장치는 두께전반에 걸친 변형을 측정할수 있게 했다. 또한 전단부의 부위별 변형도의 관찰이 가능하고 병리적인 동맥경화증에 대한 현상과 역학적현상을 상관시킬 수 있음에 중요한 의미를 들 수 있다.

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액션러닝 교수설계에 의한 창의적 문제해결 교과의 학습성과 (Effects of an Action Learning based Creative Problem-Solving Course for Nursing Students)

  • 장금성;김남영;박현영
    • 간호행정학회지
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    • 제20권5호
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    • pp.587-598
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    • 2014
  • Purpose:This study was conducted to identify the effects of an action learning based creative problem-solving (CPS) course on problem solving, creativity and team-member exchange in nursing students. Methods: A quasi-experimental study applying a non-equivalent control group pre-post design was employed. Sophomore nursing students (32 in the experimental group and 33 in the control group) were recruited from a university in G-city, Korea. Problem solving, creativity and team-member exchange were measured for the pretest and posttest using self-report questionnaires. Kolmogorov-Smirnov test, Chi-square, Fisher's exact test, t-test, and ANCOVA with SPSS/Win 20.0 program were used to analyze the data. Results: The scores for problem solving, creativity and team-member exchange in the experimental group were significantly higher than those of the control group. Conclusion: Results of this study indicate that an action learning based CPS course is an effective teaching method to improve nursing students' competencies. In the future longitudinal studies are needed to assess the long term effects of the course.

청소년기의 부모감독 변화에 대한 부모애착의 효과 (Effects of Adolescents' Attachment to Their Parents on the Longitudinal Changes in Parental Monitoring)

  • 정윤주
    • 가정과삶의질연구
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    • 제32권1호
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    • pp.1-12
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    • 2014
  • The purpose of this study was to examine: (1) whether the level of parental monitoring changes during adolescence; (2) if it changes, what is the pattern of the change; and (3) whether the effects of adolescents' attachment to their parents on parental monitoring are dependent on time. Six waves of data from the Korea Youth Panel Study (KYPS) were used to address the research questions. The participants of the KYPS were 3,449 (1,725 boys and 1,724 girls) adolescents who participated in the study once a year for 6 years (from the 2nd grade in middle school until their high school graduation). Latent growth modeling (LGM) was used to analyze the data. The findings are as follows: the level of parental monitoring significantly increased over the six waves of the study, and the adolescents' attachment to their parents was a time-dependent predictor of parental monitoring. The results indicate that the quality of adolescents' attachment to their parents is an important factor that makes a difference in the level of parental monitoring by, possibly, affecting the level of adolescents' disclosure to their parents.

우울증 치료에서의 어려운 문제들 (Difficult Clinical Problems of Treatment in Depression)

  • 민경준
    • 생물정신의학
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    • 제8권1호
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    • pp.37-46
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    • 2001
  • Whenever a clinician manages the patients with depression, he may meet various problems that make it difficult to treat them. Even though he has good skills and knowledge about depression, some barriers will be appear during his practice. In general, the difficulties in treating depression are treatment-resistance, adverse effects of antidepressants, pregnancy in female patients, comorbid medical conditions, poor compliance, drug-drug interactions, and so on, which are related with pharmacological treatments. Here, only the two of them, the treatment-resistant depression and difficult problems concerned with pregnancy, were discussed. Some level of treatment resistance is the norm rather than the exception. As the treatment failure stems from inadequate treatment, it is important that the clinician should prescribe medications with sufficient doseage and adequate duration. And to overcome the treatment resistant depression the polypharmacy is necessary, in that case, the side effects and toxicities should be explored and managed immediately. So the clinician have to learn more about the pharmacokinetic and pharmacodynamic mechanisms of each drugs used in treatment of depression. When the risk of the fetus by the exposure is higher than the risk of untreated maternal psychiatric disorder, psychotropic medications should be used during pregnancy. Women who are maintained on psychotropics and become pregnant, as well as women with the new onset of psychiatric symptoms during pregnancy, should be carefully reassessed. However, data concerning the potential risk of long-term behavioral changes following prenatal exposure to psychotropics is rare, so further longitudinal follow-up studies are needed.

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Pharmacognostical Evaluation of Trachyspermum roxburghianum (DC) Craib Fruits

  • Verma, Nitin;Khosa, R.L.
    • Natural Product Sciences
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    • 제17권1호
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    • pp.45-50
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    • 2011
  • Sophisticated modern research tools for evaluation of medicinal plants are available but microscopic methods are one of the simplest and cheapest methods to establish the identity of the source materials. Pharmacognostical investigation of the dried, powdered and anatomical sections of the fruits of Trachyspermum roxburghianum (DC) Craib was carried out to determine its macro and microscopical characteristics along with its physical constants. Externally, the fruits, yellowish or greenish brown in colour are elongated, elliptical, slightly curved, prominently ridged and longitudinal. As seen in transectional views of the fruits from Trachyspermum roxburghianum, the mericarp has concave sides called commissural surfaces and a convex outer side called the dorsal surface. The mericarp has three primary ridges alternating with two secondary ridges on the dorsal side. On the commissural side, there are two primary ridges which are lateral in position and two secondary ridges in the commissural side. The seed is attached to the pericarp by a short stalk called a raphe. Circular, four-lobed calcium oxalate crystals are fairly abundant in the endosperm. Phytochemical studies revealed the presence of phenolic compounds, triterpenoids, proteins and sugars. The pharmacognostical profile of the fruits will assist in standardization for quality, purity and sample identification.

산악지형에서 효율적인 2-Arch 터널의 설계사례 (Practical 2-Arch Road Tunnel Design in Mountainous area)

  • 정경한;이주공;한성수;황용섭;김지성
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2005년도 지반공학 공동 학술발표회
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    • pp.601-612
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    • 2005
  • In mountainous area, Two parallel tunnels have been usually recognized as a road tunnel which has benefits in aspects of cost and stability. However, Design and construction of 2-Arch road tunnel are growing recently due to environmental destruction, compensation of land and difficulty of route separation. As studies are mainly undergoing on only guaranteeing stability and developing a waterproofing-drainage system to avoid water leakage through comprehension for characteristics of 2-arch tunnel behaviors, there is a tendency to evaluate quantity of support by empirical method with a tunnel which has a complicated cross-section and lack of construction ability. In this study, therefore, we made a plan of tunnel cross-section which had shown good construction ability and developed the waterproofing-drainage system which is able to solve the water leakage problem fundamentally by analyzing precedented 2-arch tunnels and investigating their sites in and out of nation. We also determined fixed quantity of support by a large-scale model test and numerical analysis. We want to contribute to 2-arch tunnel design hereafter introducing design procedure and method applied here.

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자가 조혈모세포 이식환자와 동종 조혈모세포 이식환자의 삶의 질의 비교 (Comparison of Quality of Life of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation Recipients)

  • 김은지
    • 종양간호연구
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    • 제8권1호
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    • pp.50-60
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    • 2008
  • Purpose: The purpose of this study was to compare Quality of life (QOL) in type and time after Hematopoietic stem cell tansplantation (HSCT) for patients with hematologic cancer. Method: This study was cross-sectional. The autologous recipients was 120, the allogeneic recipients was 237. The obtained data were analyzed using T-test, One-way ANOVA, Scheffe's test. Results: No significant differences were total QOL between the autologous and allogeneic recipients. But the autologous recipients reported better status than the allogeneic recipients in physical domain, especially 1-3 yr after HSCT. There was poorer QOL of 1-3 yr compared to 1 yr after HSCT in physical, psychological and social domain between the two groups. QOL in time after HSCT of the autologous recipients was significance differences in psychological, social domain. And QOL in time after HSCT of the allogeneic recipients was significant differences in physical, psychological and social domain. Conclusions: QOL of recipients undergoing HSCT is recovered beyond 3 yr point. Accordingly, long term care and service is essential to recipients undergoing HSCT. And further studies with a longitudinal design are necessary.

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Spatial Analysis on Marine Atmosphere Boundary Layer Features of SAR Imagery Using Empirical Mode Decomposition

  • Jo, Young-Heon;Oliveira, Gustavo Henrique;Yan, Xiao-Hai
    • 대한원격탐사학회지
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    • 제33권4호
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    • pp.351-358
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    • 2017
  • A new method to decompose the footprints of marine atmosphere boundary layer (MABL) on Synthetic Aperture Radar (SAR) imagery into characteristic spatial scales is proposed. Using two-dimensional Empirical Mode Decomposition (EMD) we obtain three Intrinsic Mode Functions (IMFs), which mainly present longitudinal rolls, three-dimensional cells and atmospheric gravity waves (AGW). The rolls and cells have spatial scales between 3.0 km and 3.8 km and between 5.3 km and 7.1 km, respectively. Based on previous observations and mixed-layer similarity theory, we estimated MABL's depths that vary from 0.95 km to 1.2 km over the rolls and from 3.0 km to 3.8 km over the cells. The AGW has maximum spectrum at 14.3 km wavelength. The method developed in this work can be used to decompose other satellite imageries into individual features through characteristic spatial scales.

뇌자기공명영상의 노화에 따른 변화 (A Review of Brain Magnetic Resonance Imaging Correlates of Successful Cognitive Aging)

  • 지은경;정인원;윤탁
    • 생물정신의학
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    • 제21권1호
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    • pp.1-13
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    • 2014
  • Normal aging causes changes in the brain volume, connection, function and cognition. The brain changes with increases in age and difference of gender varies at all levels. Studies about normal brain aging using various brain magnetic resonance imaging (MRI) variables such as gray and white matter structural imaging, proton spectroscopy, apparent diffusion coefficient, diffusion tensor imaging and functional MRI are reviewed. Total volume of brain increases after birth but decreases after 9 years old. During adulthood, total volume of brain is relatively stable. After 35 years old, brain shrinks gradually. The changes of gray and white matters by aging show different features. N-acetylaspartate decreases or remains unchanged but choline, creatine and myo-inositol increase with aging. Apparent diffusion coefficient decreases till 20 years old and then becomes stable during adulthood and increase after 60 years old. Diffusion tensor properties in white matter tissue are variable during aging. Resting-state functional connectivity decreases after middle age. Structural and functional brain changes with normal aging are important for studying various psychiatric diseases such as dementia, schizophrenia and bipolar disorder. Our review may be helpful for studying longitudinal changes of these diseases and successful aging.

제주도 주변해엽 고등어 포착망의 연구 - 1 . 정수에 있어서 망형 변화에 관한 모형실험 - (Studies on the Mackerel Purse Seine Operation in the Sea Area of Cheju Island - 1 . Model Experiment on the Changes of Net Shape in Stagnant Water -)

  • 박정식
    • 수산해양기술연구
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    • 제22권2호
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    • pp.7-15
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    • 1986
  • In order to investigate the performance for the mackerel purse seine of one boat purse seiner using in the sea area of Cheju Island, a model net is made of the scale of 1/400 of its full scale, and model test on the shape of net and the tension of purse line is carried out in the stagnant water channel of the circulating water tank. Designing and testing for the model net are based on the Tauti's law. The obtained results are as follows; 1. The sinking rate of net is maximized the value of 6.40 m/min from 5 to 10 minutes after shooting net, and the mean value is 6.13 m/min. 2. The enclosed area formed with the float line after pursing operation is 76-84% of the area which is formed immediately after the shooting operation. At that time, purse seine is pulled inward the circle of surrounding net about 26.5% of the diameter. 3. In operating, when longitudinal section area of the central part of the net is maximized, the split area of both the wing-ends is 31-32% of the former. 4. When the time for the completing of pursing is 20 minutes, the maximum tension of the purse line is about 10.2 tons.

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