• Journal of Korean Neurosurgical Society
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• 제61권3호
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• pp.393-401
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• 2018

The prognosis of brain tumors in children has improved for last a few decades. However, the prognosis remains dismal in patients with recurrent brain tumors. The outcome for infants and young children in whom the use of radiotherapy (RT) is very limited because of unacceptable long-term adverse effect of RT remains poor. The prognosis is also not satisfactory when a large residual tumor remains after surgery or when leptomeningeal seeding is present at diagnosis. In this context, a strategy using high-dose chemotherapy and autologous stem cell transplantation (HDCT/auto-SCT) has been explored to improve the prognosis of recurrent or high-risk brain tumors. This strategy is based on the hypothesis that chemotherapy dose escalation might result in improvement in survival rates. Recently, the efficacy of tandem HDCT/auto-SCT has been evaluated in further improving the outcome. This strategy is based on the hypothesis that further dose escalation might result in further improvement in survival rates. At present, the number of studies employing tandem HDCT/auto-SCT for brain tumors is limited. However, results of these pilot studies suggest that tandem HDCT/auto-SCT may further improve the outcome. In this review, we will summarize our single center experience with tandem HDCT/auto-SCT for recurrent or high-risk brain tumors.

• 의학교육논단
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• 제20권3호
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• pp.128-134
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• 2018

Medical education, competency, and outcome-based medical education started as part of the basic medical education curriculum in advanced countries 20 years ago, and such an approach was adopted in residency training. General competency training is at the core of residency training in advanced countries, and it goes beyond competency and outcome-based training to the extent that in a milestone training system, competency development is expected and measured with set competency achievements at each level. Recently, for the purpose of ensuring that doctors uphold patient safety and fulfill their obligations, entrustable professional activities (EPA) were applied at the beginning of residency when doctors move away from clinical trials and start actual care. The adoption of EPA in all residency training curriculum has spread very rapidly in the United States, United Kingdom, and Canada. Presently, Korea lags behind other countries significantly as the adoption of competency and outcome-based medical education in residency training has just begun. It is time to identify the current state of the Korean residency training system, and then design and practice a well-established system with a long-term view based on cooperation across the whole medical industry.

• Journal of Korean Neurosurgical Society
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• 제30권sup1호
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• pp.108-114
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• 2001

Objective : Posterior lumbar interbody fusion(PLIF) provides the favorable outcome to degenerative lumbar disease, especially isthmic spondylolisthesis. To determine the long-term effect of PLIF using psterior movable segment, we analysed the results of follow-up radiologic changes and surgical outcome retrospectively Patients and Method : During the past 11 years(1989. 1.-1999. 9.), 148 patients with symptomatic lumbar spondylolisthesis were managed at our department and the clinical wants were throughly recieved and final outcome is determined at last follow up. PLIF using antogenous bone(posterior movable segment, iliac bone and rib) were performed in 106 case. Results : After an average follow-up period of 33 months(range ; 15-58 months), the results were excellent in 66 cases, good in 37 cases, fair in 2 cases and poor in 1 cases. And the satisfactory results were 103 cases(98.2%) in PLIF,. Conclusion : In conclusion, patients who underwent PLIF with autologous bone graft had good clinical and radiological outcomes without significant neurological complications.

• Journal of Korean Dental Science
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• 제17권1호
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• pp.45-52
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• 2024

Purpose: To investigate the 5-year outcome of dental implants placed in a grafted maxillary sinus using recombinant human bone morphogenetic protein-2 (rhBMP-2). Materials and Methods: We retrospectively analyzed 27 implants after maxillary sinus floor augmentation (MSFA) using rhBMP-2 in 16 patients between January 2016 and March 2017. The study evaluated two outcome variables: (1) 5-year cumulative survival and success rate of the implant after functional loading and (2) marginal bone loss (MBL) for implant failure. Results: The average residual bone height was 4.78±1.53 mm. The healing period before loading was 8.35±2.34 months. The crown-to-implant ratio was 1.31±0.26. The 5-year cumulative survival and success rate after functional loading were 100% and 96.3%, respectively. The 5-year average MLB was 0.89±0.82 mm. Conclusion: Placing dental implants with MSFA using rhBMP-2 is a reliable procedure with favorable long-term survival and success rates.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제9권2호
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• pp.200-209
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• 2006

목 적: 만성 기능성 변비 환아의 임상 증상과 경과를 관찰하고, 장기적인 치료 성적을 평가하여 치료 결과에 영향을 미치는 요인을 분석함으로써 변비 치료에 도움을 얻고자 하였다. 방 법: 2001년 3월부터 2005년 6월까지 순천향대학교 부천병원에서 만성 기능성 변비로 진단받고 1개월 이상 치료받고 경과를 볼 수 있었던 63명의 환아를 대상으로 임상 증상, 치료에 따른 경과, 치료 결과 및 재발 여부 등을 조사하고 예후와 관련된 요인을 분석하였다. 결 과: 대상 환아들의 성별 분포는 남아가 35명(55.6%), 여아가 28명(44.4%)이었고 남아가 여아에 비해 유분증이 유의있게 많았다. 발병 연령은 평균 $21.1{\pm}23.5$ (1.9~84.0)개월이었으며 진단 당시 평균 연령은 $47.1{\pm}34.2$ (6.9~138.0)개월이었다. 치료 전 주당 배변 횟수는 평균 $3.2{\pm}2.3$ (0.5~10.0)회였고, 변비와 동반된 증상으로는 유분증이 34명(54.0%), 굵은 변이 30명(47.6%), 배변 횟수의 감소가 20명(31.7%), 배변 시 힘주기와 변 참기가 각각 19명(30.2%) 순이었다. 추적 관찰 기간은 평균 $34.2{\pm}14.6$ (3.6~60.0)개월이었으며 전화 통화 당시 변비 증상으로부터 회복된 환아는 44명(69.8%)이었고 증상이 남아있었던 환아는 19명(30.2%)이었다. 변비에서 회복된 환아들의 임상적 경과를 살펴보면 유분증이 있었던 환아들이 유분증이 없어진 시간은 치료 시작 후로 부터 평균 $4.3{\pm}2.4$ (1.0~36.0)개월이었으며, 배변시 힘을 많이 주었던 환아들이 변을 힘주지 않고 누게 된 시간은 평균 $5.0{\pm}1.4$ (0.8~36.0)개월이었고, 변을 참았던 환아들이 변을 참지 않게 된 시간은 평균 $5.0{\pm}3.1$ (1.0~36.0)개월이었다. 변비가 재발한 경우는 15명(23.8%)이었으며 남아가 9명(60%), 여아가 6명(40%)이었다. 치료 종료 후로부터 재발하기 까지의 기간은 평균 $2.9{\pm}1.9$ (1.0~6.0)개월이었으며 성별, 발병 나이, 변비의 증상, 치료 시작 전 증상의 지속 기간, 진단 당시 유분증 유무, 이유식 시작 시기와 대변 가리기 훈련 시기 등은 재발에 영향을 미치지 않았으며 치료 기간이 재발에 영향을 미치는 유일한 인자였다. 결 론: 대부분의 소아 만성 기능성 변비 환아가 치료 시작 후 5개월 경에 증상이 회복되었으나 치료 종료 후 약 3개월 내에 재발할 수 있으며 치료 기간이 재발 여부에 영향을 미치는 것으로 보아 충분한 기간 동안 치료하는 것과 정기적인 추적 관찰이 중요하다고 하겠다.

• Journal of Korean Neurosurgical Society
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• 제44권4호
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• pp.228-233
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• 2008

Objective : The standard treatment strategy of intracranial aneurysms includes either endovascular coiling or microsurgical clipping. In certain situations such as in giant or dissecting aneurysms, bypass surgery followed by proximal occlusion or trapping of parent artery is required. Methods : The authors assessed the result of extracranial-intracranial (EC-IC) bypass surgery in the treatment of complex intracranial aneurysms in one institute between 2003 and 2007 retrospectively to propose its role as treatment modality. The outcomes of 15 patients with complex aneurysms treated during the last 5 years were reviewed. Six male and 9 female patients, aged 14 to 76 years, presented with symptoms related to hemorrhage in 6 cases, transient ischemic attack (TIA) in 2 un ruptured cases, and permanent infarction in one, and compressive symptoms in 3 cases. Aneurysms were mainly in the internal carotid artery (ICA) in 11 cases, middle cerebral artery (MCA) in 2, posterior cerebral artery (PCA) in one and posterior inferior cerebellar artery (PICA) in one case. Results : The types of aneurysms were 8 cases of large to giant size aneurysms, 5 cases of ICA blood blister-like aneurysms, one dissecting aneurysm, and one pseudoaneurysm related to trauma. High-flow bypass surgery was done in 6 cases with radial artery graft (RAG) in five and saphenous vein graft (SVG) in one. Low-flow bypass was done in nine cases using superficial temporal artery (STA) in eight and occipital artery (OA) in one case. Parent artery occlusion was performed with clipping in 9 patients, with coiling in 4, and with balloon plus coil in 1. Direct aneurysm clip was done in one case. The follow up period ranged from 2 to 48 months (mean 15.0 months). There was no mortality case. The long-term clinical outcome measured by Glasgow outcome scale (GOS) showed good or excellent outcome in 13/15. The overall surgery related morbidity was 20% (3/15) including 2 emergency bypass surgeries due to unexpected parent artery occlusion during direct clipping procedure. The short-term postoperative bypass graft patency rates were 100% but the long-term bypass patency rates were 86.7% (13/15). Nonetheless, there was no bypass surgery related morbidity due to occlusion of the graft. Conclusion : Revascularization technique is a pivotal armament in managing complex aneurysms and scrupulous prior planning is essential to successful outcomes.

• 한국콘텐츠학회논문지
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• 제15권9호
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• pp.317-328
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• 2015

본 연구는 요양시설 직접돌봄제공자의 기능유지간호에 대한 자기효능감 및 결과기대감 도구를 번역한 한국판 기능유지간호에 대한 자기효능감 및 결과기대감 도구의 타당도 및 신뢰도 분석을 통해 문화적인 차이가 있는 원 도구를 한국의 노인 요양시설에 근무하는 간호사에게 적용할 수 있는지 검증하는데 그 목적이 있다. 본 연구의 대상자는 전국 69개의 요양시설에 근무하는 간호사 187명으로 자료수집은 구조화된 설문지를 이용하였다. 수집된 자료는 SPSS/WIN 21.0과 AMOS 22.0을 이용하여 분석하였으며 구성타당도 검정은 확인적 요인분석으로 시행하였고, 준거타당도 검증을 위해 기능유지간호에 대한 자기효능감 및 결과기대감과 기능유지간호에 대한 지식, 직무만족과의 상관관계를 이용하였다. 연구결과 확인적 요인분석을 통해 구성타당도가 입증되었고, 준거타당도가 검증되었다. 또한, 신뢰도 분석을 통해 도구의 신뢰도가 확인되었다. 본 연구를 통해 번역된 한국어판 기능유지간호에 대한 자기효능감 및 결과기대감 도구가 국내에서 사용할 수 있는 도구임이 검증되었고, 추후 시설 입소노인의 기능유지간호를 위한 초석이 될 것으로 사료된다.

• Clinics in Shoulder and Elbow
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• 제26권3호
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• pp.231-237
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• 2023

Background: In the past decade, the number of anatomic total shoulder arthroplasty (aTSA) procedures has steadily increased. Patients over 65 years of age comprise the vast majority of recipients, and outcomes have been well documented; however, patients are opting for definitive surgical treatment at younger ages.We aim to report on the effects of age on the long-term clinical outcomes following aTSA. Methods: Among the patients who underwent TSA, 119 shoulders were retrospectively analyzed. Preoperative and postoperative clinical outcome data were collected. Linear regression analysis (univariate and multivariate) was conducted to evaluate the associations of clinical outcomes with age. Kaplan-Meier curves and Cox regression analyses were performed to evaluate implant survival. Results: At final follow-up, patients of all ages undergoing aTSA experienced significant and sustained improvements in all primary outcome measures compared with preoperative values. Based on multivariate analysis, age at the time of surgery was a significant predictor of postoperative outcomes. Excellent implant survival was observed over the course of this study, and Cox regression survival analysis indicated age and sex to not be associated with an increased risk of implant failure. Conclusions: When controlling for sex and follow-up duration, older age was associated with significantly better patient-reported outcome measures. Despite this difference, we noted no significant effects on range of motion or implant survival. Level of evidence: IV.

• Journal of Yeungnam Medical Science
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• 제37권4호
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• pp.337-340
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• 2020

Ureterosciatic hernia is extremely rare. In ureteral herniation, ureter prolapses occur through either the greater or lesser sciatic foramen. Atrophy of the piriformis muscle, hip joint diseases, and defects in the parietal pelvic fascia are predisposing factors for the development of ureterosciatic hernia. Most symptomatic patients have been treated surgically, with conservative treatment reserved only for asymptomatic patients. To the best of our knowledge, long-term follow-up outcomes after ureterosciatic hernia management are sparse. In this paper, we report the case of a 68-year-old woman who presented with colicky left abdominal pain. After computed tomography (CT) scan and anterograde pyelography, she was diagnosed ureterosciatic hernia with obstructive uropathy. We performed ureteral balloon dilatation and double-J ureteral stent placement. After this minimally invasive procedure, CT scan demonstrated that the left ureter had returned to its normal anatomical position without looping into the sciatic foramen. The patient remained asymptomatic with no adverse events 7 years after the minimally invasive procedures. This brief report describes ureterosciatic hernia successfully managed with minimally invasive procedures with long-term follow-up outcomes.

• 대한간호학회지
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• 제41권4호
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• pp.528-538
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• 2011

Purpose: The purpose of the study was to examine the effects of multisensory stimulation (MSS) using familiarity on persons with dementia (PWDs) residing in nursing homes in Korea. Methods: A nonequivalent control group with pre and posttests was used. Fifty one PWDs were included if they: 1) were over 65 yr old, 2) were diagnosed with dementia, 3) had no visual or speech impairments, 4) were able to communicate, and 5) had spent more than one month in a nursing home. The experimental group (n=25) received a 55 min MSS program twice a week for 10 weeks. The outcome variables included were cognition, activities of daily living, grip strength, depression, wandering, and aggressive behaviors. Repeated ANOVA was used for data analysis. Results: There were no significant differences in demographics or the main variables at pretest. Cognition, depression, wandering, and aggressive behaviors were significant over time between the two groups. Grip strength was only significant when accounting for interaction between group and time. Conclusion: An intervention of MSS using familiarity was marginally effective in improving cognition, depression, wandering, and aggression. Future study is suggested with a larger sample and longer treatment to retest the effects of MSS.