• Title/Summary/Keyword: long term stability

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Characterization to flammable gas $\alpha$-$Fa_{2}O_{3}/SnO_{2}$ system thin film fabricated by APCVD (APCVD법에 위해 제조된 $\alpha$-$Fa_{2}O_{3}/SnO_{2}$계 박막의 가연성 가스 감지 특성 평가)

  • 심성은;이세훈;최성철
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.10 no.2
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    • pp.105-110
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    • 2000
  • The $\alpha$-$Fa_{2}O_{3}/SnO_{2}$ thin film gas sensor was fabricated by APCVD and heat treated. The gas sensitivity to flammable gases ($CH_4$, $H_2$, LPG) was measured. This device was to heat treatment at $400^{\circ}C$, $450^{\circ}C$, $500^{\circ}C$, $550^{\circ}C$, $600^{\circ}C$ for 2 h to enhance the gas sensitivity. The heat treated device at $500^{\circ}C$ for 2 h had the best properties and especially it shows high sensitivity to H2 gas. The sensitivity to gases was studied in the temperature range from lOoC to $300^{\circ}C$ in order to find the optimum detection temperature. In the range of detection from 500 ppm to 10,000 ppm at $175^{\circ}C$ the fabricated device showed that the gas sensitivity to $H_2$ was from 62%~76% and to $CH_4$ was from 16 %~58% and to LPG was from 8%~37 %. The sensitivity difference between heat treated device and as fabricated one was about 10 8 The long-term stability to LPG at 1,000 ppm was converged to sensitivity of 30 %.

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Effect of Low-Intensity Pulsed Ultrasound on Bone Healing around Titanium Implant in Tibia of Diabetes Mellitus Induced Rats (당뇨유도 백서 경골에 티타늄 임플란트 매식 시 저출력 초음파 적용이 골치유에 미치는 영향)

  • Seo, Young-Kyo;Kim, Uk-Kyu;Park, Sang-Jun;Lee, Soo-Woon;Kim, Yong-Deok;Hwang, Dae-Seok
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.34 no.3
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    • pp.163-172
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    • 2012
  • Purpose: Diabetes mellitus (DM) has been shown to alter the properties of the bone and impair bone healing around a titanium implant. The aim of this study is to investigate whether the low-intensity pulsed ultrasound (LIPUS), which has been known to stimulate the bone healing, improve the osseointegration of the titanium implant in tibia of DM-induced rats. Methods: 16 rats were received streptozotocin (60 mg/kg) for inducing diabetes. A total number of 32 titanium implants were placed bilaterally into both tibiae of these rats. The right tibia of each rat received LIPUS application (10 min/day) during 7 days post-operation, while the left side received no treatment. The study was carried on for six weeks and the rats were sacrificed at 1, 2, 4, and 6 weaks postoperatively (4 rats for each week) for histomorphometric and histologic analysis. Bone-implant contact and bone area were measured. Comparisons between the groups were made using statistical analysis on histomorphometric analysis. Results: The histomorphometry parameters showed that the bone-implant contact and the bone area values have decreased in the late osseointegration periods (4, 6 weeks) compared to the early osseointegration periods (1, 2 weeks) in both two groups. The bone-implant contact values of the LIPUS group were somewhat higher than those of controls at 1, 2 weeks, but the difference was not statistically significant. The bone area values of the LIPUS group were also higher than those of controls at 1, 2 weeks, but the difference was not statistically significant as well. Conclusion: Results of this study indicate that LIPUS may have positive effects on early osseointegration but could not improve the long term stability of dental implants.

Development and Validation of Reference Material for Proficiency Testing of Blood Heavy Metals in Environmental Biomonitoring (환경 바이오모니터링에서의 혈중 중금속 분석 숙련도 시험을 위한 표준물질 제조 및 적용성 평가)

  • Im, Hosub;Yang, Minho;Oh, Selim;Kim, Soyoung;Jung, Hojun;Cho, Yong Min;Lee, Jung Sub;Kim, Hyun Jeong;Lee, Chae Kwan;Moon, Chan-Seok;Lee, Jong-Wha
    • Journal of Environmental Health Sciences
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    • v.42 no.6
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    • pp.450-464
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    • 2016
  • Objectives: This study developed and validated reference materials (RMs) to analyze metal compounds in blood. Methods: We referred to KoNEHS (Korea National Environmental Health Survey) to estimate concentrations of blood metals (cadmium, Cd; lead, Pb; mercury, Hg) and applied analytical methods (inductively coupled plasma - mass spectroscopy, ICP-MS, for Cd and Pb; graphite furnace - atomic absorption spectrometry, GF-AAS, for Cd and Pb; and direct mercury analyzer, DMA, for Hg). Homogeneity and stability tests were carried out. In addition, certified values and uncertainties of RMs were calculated through internal and external experiments. All RMs were developed and assessed in various forms according to element, analytical method, and two types of concentration levels high concentration for occupational exposure and low concentration for environmental exposure. Results: All samples showed acceptable homogeneity, except for low concentration of Cd in the GF-AAS method. Short- and long-term stabilities were satisfied by ANOVA testing. In the inter-laboratory comparison, robust medians were lower than the certified values of all RMs (robust median/reference value; $1.301/1.327{\mu}g/L$ for Cd, ICP-MS, low concentration; $3.152/3.388{\mu}g/L$ for Cd, ICP-MS, high concentration; $1.219/1.301{\mu}g/L$ for Cd, GF-AAS, low concentration; $3.074/3.321{\mu}g/L$ for Cd, GF-AAS, high concentration; $14.473/14.516{\mu}g/L$ for Pb, ICP-MS, low concentration; $50.069/50.114{\mu}g/L$ for Pb, ICP-MS, high concentration; $12.881/14.147{\mu}g/L$ for Pb, GF-AAS, low concentration; $47.015/47.591{\mu}g/L$ for Pb, GF-AAS, high concentration; $4.059/4.218{\mu}g/L$ for Hg, DMA, low concentration; $11.474/11.181{\mu}g/L$ for Hg, DMA, high concentration). Conclusion: This study demonstrates procedures for developing and validating RMs for biomonitoring in the field of the environmental health.

Field Application of a Precast Concrete-panel Retaining Wall Adhered to In-situ Ground (원지반 부착식 판넬옹벽의 현장 적용성 평가)

  • Min, Kyoung-Nam;Lee, Jae-Won;Lee, Jung-Gwan;Kang, In-Kyu;Ahn, Tae-Bong
    • The Journal of Engineering Geology
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    • v.26 no.1
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    • pp.51-61
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    • 2016
  • New building methods are needed to aid increased inner-city redevelopment and industrial construction. A particular area of improvement is the efficient use of cut slopes, with the minimization of associated problems. A retaining wall of precast panels can resist the horizontal earth pressure by increasing the shear strength of the ground and reinforcing it through contact with the panels. Precast panels allow quick construction and avoid the problem of concrete deterioration. Other problems to be solved include the digging of borrow pits, the disposal of material cut from the slope, and degradation of the landscape caused by the exposed concrete retaining wall.This study suggest the methods of improvement of an existing precast panel wall system by changing the appearance of the panels to that of natural rock and improving the process of adhering the panel to a vertical slope. The panels were tested in the laboratory and in the field. The laboratory test verified their specific strength and behavior, and the field test assessed the panels' ground adherence at a vertical cutting. Reinforcement of the cutting slope was also measured and compared with the results of 3D numerical analysis. The results of laboratory test, identified that the shear bar increase the punching resistance of panel. And as a results of test construction, identified the construct ability and field applicability of the panel wall system adhered to in-situ ground. In addition to that, extended measurement and numerical analysis, identified the long-term stability of panel wall system adhered to in-situ ground.

Safety Test of Brown Rice Expressing Arabidopsis Calcium Transporter by Feeding Trial in Mice (애기장대 칼슘수송체를 발현하는 형질전환 현미의 생쥐 식이를 통한 안전성 평가)

  • Kim, Kyung-Min;Kim, Chang-Kil;Kim, Byung-Oh
    • Journal of Life Science
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    • v.18 no.10
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    • pp.1390-1394
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    • 2008
  • Previously, we found that the transgenic rice plants over-expressing the Arabidopsis $H^+/Ca^{2+}$ antiporter CAX 1 (accession no. U57411) gene accumulated 2.7 to 7.5-fold more calcium in the T3 rice grains as compared to those of control. To examine physiological safety of the $T_3$ rice grains, the effect of the $T_3$ brown rice on change in levels of body weight and white blood cells was compared with that of the control Ilpum brown rice by feeding trial in mice. During the feeding trial for one month, there was no significant difference between two mice groups, which were fed by the $T_3$ brown rice or Ilpum brown rice. There were no detectable differences in their effects on immune functions including plaque-forming unit, peritoneal macrophage number, and NK-cell activity. In addition, biochemical analysis of the blood failed to exhibit any difference between two mice groups. Together, these results suggested that the $T_3$ brown rice, which was produced from a genetically modified organism (GMO), might be safe and possess a potential to be applicable as calcium-fortified feed or food. Long-term safety of the $T_3$ brown rice, however, remains to be elucidated.

Stable Transmission and Expression of TPO Transgene up to 10 Generation in the Transgenic Mice (형질전환 생쥐에서 제10세대까지 TPO 유전자의 안정적 전이와 지속적인 발현)

  • 정진우;오건봉;한용만;이경광
    • Korean Journal of Animal Reproduction
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    • v.27 no.1
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    • pp.9-14
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    • 2003
  • The pBT-L transgenic mice carrying human TPO gene in conjunction with bovine $\beta$-casein promoter express human TPO in milk during lactation. In this study, stability of germ line transmission and expression of pBT-L transgene integrated into host chromosome were monitored up to generation F10 of transgenic pBT-L/15 line. When male mouse of generation F8 was crossbred with normal females, approximately half of offsprings (51.3$\pm$18.98%) were identified as transgenic mice. Generation F9 and F 10 mice also showed similar transmission rates (43.8$\pm$18.98% and 71.4$\pm$26.98%, respectively), implying that pBT-L transgene can be transmitted stably up to long term generation in the transgenic mice. Expression levels of human TPO from milk of generation F9 and F10 mice were 1.1$\pm$0.33 mg/ml and 1.1 $\pm$0.45 mg/ml, respectively, which are similar to expression level of generation F2 mice. In conclusion, our results suggest that transgenic animals once established will continuously pass their transgenes to the progeny through the breeding program with the same productivity of human protein in their milk.

Coracoclavicular Ligament Augmentation Using TightRope® for Acute Acromioclavicular Joint Dislocation : Surgical Technique and Preliminary Results (TightRope®를 이용한 급성 견봉 쇄골 관절 탈구의 치료 : 수술 술기 및 예비 보고)

  • Cho, Chul-Hyun;Sohn, Sung-Won;Kang, Chul-Hyung;Oh, Geon-Myeoung
    • Clinics in Shoulder and Elbow
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    • v.11 no.2
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    • pp.165-171
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    • 2008
  • Purpose: The purpose of this study was to introduce a new surgical technique and to evaluate the preliminary results after operative treatment with using TightRope$^{(R)}$ for treating acute acromioclavicular joint dislocation. Material and Methods: We studies 10 patients who were followed up for more than 6 months after operative treatment with using an TightRope$^{(R)}$. A longitudinal incision approximately 4cm in length was made from 1cm medial to the acromioclavicular joint to the coracoid process, and then coracocalvicular ligament augmentation using TightRope$^{(R)}$ was done after splitting the deltoid. For postoperative stability, two 1.6 mm Kirschner wires were inserted temporarily across the acromioclavicular joint in all cases. The radiologic results on the serial plain radiographs and the clinical results according to the UCLA score were analyzed. Results: Radiologically, 7 cases showed anatomical reduction, 2 cases showed a slightly loss of reduction and 1 case showed partial loss of reduction. Clinically, 6 cases were excellent, 3 cases were good and 1 case was fair. Conclusion: Coracoclavicular ligament augmentation using TightRope$^{(R)}$ for treating acute acromioclavicular joint dislocation is a minimally invasive, safe procedure that provides satisfactory radiologic and clinical preliminary results. Yet the long-term results have to be analyzed to determine the final results of this procedure.

Application of biofilter for removing malodomus gas generated from compost factory (퇴비화 '공장에서 발생되는악취'를 제거하기 위한 Biofilter의 적용)

  • Kim, Chang-Il;Lee, Jae-Ho;Kim, Dae-Seung;Nam, Sang-Il;Nam, Yi
    • Journal of Korea Soil Environment Society
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    • v.4 no.3
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    • pp.45-56
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    • 1999
  • A biofilter was established to remove the ammonia, which is representative nitrogen-contained malodorous gas. in a compost factory. Removal efficiency of ammonia and hydrogen sulfide also was investigated. A quantity of malodor gas produced in a compost factory was affected greatly by the weather. compost states and working condition of a fertilizing mixer, and the produced gas concentrations doubled by above various parameters. By operating a water scrubbing system for removing water-soluble malodorous gases effectively. we could improve the removal efficiency over three times. We investigated long-term stability of biofilter under continuous gas flow(SV=500h-1) for 100 days. The results showed 30 days of microbial retention time. After the days, deodorization efficiency of biofilter was kept steady state. and the removal efficiency was kept over 95% for ammonia and 97% for hydrogen so]fide. respectively. The electric consumption of the biofilter, which could treat malodorous gas of 100$\textrm{m}^3$/min, applied in the compost factory was evaluated about 80u0day and water consumption was 80~100$\ell$/day. These results concluded that the biofilter is a excellent deodorization technology as well as cost-effective for removing malodorous gas produced in a compost factory.

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A Study on the Applicability of GSTAR-1D to the Riverbed-Level Variation in the Geum River (GSTAR-1D 모형의 금강 하상변동예측 적용성에 관한 연구)

  • Chung, Sung-Young;Park, Bong-Jin;Jung, Kwan-Sue
    • Proceedings of the Korea Water Resources Association Conference
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    • 2006.05a
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    • pp.1611-1615
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    • 2006
  • The purpose of this study is to simulate the riverbed profile changes downstream of Daecheong re-regulation dam from 1988 to 2001, to evaluate the model's applicability and to predict a long-term riverbed-level variation between 2002 and 2017. As a result of simulation 14 sediment transport equations provided by GSTAR-1D, it was found that Acker's & White formula was the most stable relatively. The interval used to calculate its stability was 7 days for bankful discharge$(1,000m^2/s)$, 3 days for daily maximum flow$(4,273m^2/s)$, 1 day for hourly maximum flow$(7,605m^2/s)$ and minimum flow$(8.5m^2/s)$. The simulation results of river bed changes were evaluated and compared to its measure data from 1988 to 2001. It was showed that there was the degradation for a section between Daecheong re-regulation dam and Maepo water stage gage station due to bed-material, and the degradation for a reach between Maepo and Gongju water stage gage station due to massive aggregate collection. Also, as a result of simulating the river profile change for 2002 to 2017, it was predicted that the section between Daecheong re-regulation dam and Geumnam Bridge would remain as the present profile and the reach between Maepo and Gongju water stage gage station would have some degradations in several parts, which would be stable as a whole unless it was due to artificial river profile change.

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Isolation and Characterization of Catalase-producing Bacteria from Soil (토양으로부터 카탈라제 생산균의 분리 및 특성)

  • Han, Kyung-Ah;Rhee, Jong-Il
    • KSBB Journal
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    • v.24 no.6
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    • pp.508-514
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    • 2009
  • This study investigated the production of catalase from Bul-kyo soil bacteria through fermentation process. Isolation and selection of bacteria was performed through chemical and physiological analysis. Catalases were produced from bacteria which belong to 3 different species (Bacillaceae bacterium BKBChE-1, Bacillus sp. BKBChE-2, Bacillus flexus BKBChE-3) confirmed by using 16S rDNA sequence method. The catalases were found to be stable in the temperature range of $30^{\circ}C-60^{\circ}C$ for BKBChE-1, BKBChE-2 and BKBChE-3 and also in the pH range of 9.0-12.0 for BKBChE-1 and BKBChE-3. Long-term stability of the catalases was about 20 days at $4^{\circ}C$. However, BKBChE-2 has kept its activity over 30 days at $4^{\circ}C$.