Lee Hyun-Seok;Jeong Han-Sin;Kim Tae-Wook;Son Young-Ik;Baek Chung-Hwan
Korean Journal of Head & Neck Oncology
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v.21
no.1
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pp.26-31
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2005
Backgrounds and Objectives: Squamous cell carcinomas of the oral cavity(SCOC) in TNM stage I & II have relatively high chance to be cured compared to those in the advanced stage, but sometimes result in the treatment failure with poor prognosis. There have been few reports on the patterns of failure and the clinical courses for SCOC in stage I & II after the failure of initial treatment. This study is directed at identifying the clinical outcomes of stage I & II SCOC and the salvage rate after initial treatment and suggesting an optimal level of treatment by analyzing the patterns of failure. Material and Methods: The medical records of 36 patients with SCOC, initially diagnosed between 1995 and 2001 as TNM stage I & II were reviewed retrospectively. The patterns of failure, salvage treatment, clinical courses, and the survival of these subjects were analyzed. The minimum follow-up period of no-evidence of disease(NED) was 12 months with an average of 32.2 months. Results: Overall rate of the treatment failure in SCOC of stage I & II was 41. 7%(15/36 cases). Most of the treatment failure in the subjects with stage I tumors occurred in regional lymph node. Local failure was the most frequent form of failure in the subjects with stage II tumors after wide excision of primary tumor with elective neck dissection and/or radiation therapy. No significant correlation was noted between the safety margin and the local failure. Elective neck dissections in stage I & II SCOC had a tendency to reduce regional failure (p=0.055). The salvage rates at 24 months were 85.7% in stage I, and 37.5% in stage II. The 3-year survival rate after the failure of initial treatment was 55.0%. Conclusion: SCOC of stage I & II after the failure of initial treatment showed poor prognosis despite of the salvage treatments. This study implies that the elective neck dissections for regional lymph node should be required for SCOC of stage I & II to reduce the treatment failure.
Park, Min-Jung;Yoon, Mi-Hye;Hong, Hae-Geun;Joe, Tae-Suk;Lee, In-Sook;Park, Jeong-Hwa;Ko, Hoan-Uk
Journal of Food Hygiene and Safety
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v.23
no.2
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pp.108-112
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2008
A survey of total aflatoxin levels was conducted on 158 samples (nuts, fermented foods and their processed products) collected in local markets in Gyeonggi-do and Domestic Internet Site. The total aflatoxins were quantified by the immunoaffinity column clean-up method followed by high performance liquid chromatography (HPLC)-fluorescence detector (FLD). Aflatoxins were found in 45(28.5%) samples including 34 nuts and nut products, 7 soybean pastes, 1 meju, 1 bean product and 2 corn snacks with a range of $0.02{\sim}3.96\;{\mu}g/kg$. These results show that the contamination level of aflatoxin in foods consumed in Korea is low compared with the standard in Korea Food Code($10\;{\mu}g/kg$ as aflatoxin $B_1$). Aflatoxin $B_1$ content was increased in peanuts and com snacks during storage but it was decreased in doenjang (soybean paste).
Formamide is a colorless fluid with ammonia odor, and irritable when inhaled. It has $LD_{50}$ value of > 5,577 mg/kg in rats for acute oral toxicity and NOAEL of 113 mg/kg/day for target organ (liver) of whole body toxicity. It is also known as reproductive toxicant (1B) and TWA(Time Weighted Average) for it is 10 ppm. Workplace measurements of work places dealing with formamide showed the ppm of all 25 samples was very lower than WEL. However, the exposure concentration can change, depending on workplace condition such as the intensity of work, operating local ventilation system, and wearing protection equipment (Respirators). Therefore, considering it with the risk of whole body toxicity and reproductive toxicity, exposure quantity of each imaginary scenario was calculated at 5.16, 1.72, and $0.43mg/m^3$. The average value was calculated at 0.02-0.58, 0.02-0.66 at 90 percent of cumulative distribution, 0.02-0.69 at 95 percent of cumulative distribution. Therefore, it was generally evaluated to be safe because all values were below 1. However, caution is required to prevent health hazard because it has hepatotoxicity and reproductive toxicity and risk of a high level momentary exposure, depending on the condition of workplace.
The subjects in this study are the residents of Busan, analyzing the perception gap between the residents adjacent to the nuclear plant and living in town, about the lawsuit of thyroid cancer damage nearby the nuclear plant, to distinguish the citizen's acceptance level about the nuclear power. 551 people(269 people adjacent to nuclear plant, 282 people in town) were face-to-face surveyed and the result showed that people's perceptions of the nuclear power has changed after the thyroid cancer damage lawsuit. In the case of the residents adjacent to the nuclear plant, it became clear that the negative perception of nuclear power became stronger due to increasing distrust and anxiety about nuclear power after the lawsuit of thyroid cancer damage nearby the nuclear plant. On the other hand, people living in town showed their positive perceptions of nuclear power despite the thyroid cancer damage lawsuit. However, two-sided perception was shown compared to the acceptance of nuclear power, since the safety and reliability of the nuclear power was analyzed as negative perception. Therefore, for the constant increased use of nuclear power in the future, national understanding and credibility, including the communication with the nation or the residents in the neighboring area of nuclear power plant, will be necessary.
In the situation that crime is diversified qualitatively and quantitatively, the mutual cooperation system between police and private security is very important to cope with the change of policing environment properly. The primary purpose of this study is to suggest the method to improve the policing service quality of police and advance sound security industry by analyzing the case of close mutual cooperation system between police and private security of USA, which can be called the best country in the field of private security. When considering the cases of USA synthetically, we can know that as the most basic characteristic, the discussion over actual cooperation method is performed on the basis of positive recognition over mutual existence of police or private security. It means that the mutual relationship is based on the basic recognition over partner relationship to meet citizen's desire for safety. While reviewing the cases of USA, Korea shall refer to the fact that social safety activities of advanced countries display effects because of many factors such as various mutual cooperation programs between police and private security, efforts of local government, high quality of private security, reliance of citizen and general understanding of police, private security and citizen to solve crime problem. As shown in the review of USA cases, when considering the fact that the mutual cooperation between police and private security is performed in the level of autonomous police, Korea shall perform autonomous police system to provide better policing service, which is close to citizen.
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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v.39
no.6
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pp.469-476
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2021
The framework plan for the development of an integrated underground space map was established of preventing ground subsidence. The mapping process is expected to be completed to the level of nationwide municipal government standards by end of this year. To facilitate the utilization of the integrated underground space map, paper-based drawings for specialized organizations in underground safety impact assessment have been provided since September 2018, and services for local government officials have been provided in the underground information utilization system since May 2019. However, the map is utilized based on the information at the time of the initial development of the map, without any updates, thereby resulting in a lack of accuracy and latest information. This has led to a decrease in the utilization and reliability of the information. Therefore, in this study, for the underground structures(subway, underground shopping mall, underground passage, underground roadway, underground parking lot, utility tunnel), which are the key components of the integrated underground space map, a standard format for the submission of completed drawings is designed in accordance with Article 42 (2) of the Special Act on Underground Safety Management, which aims at laying the foundation for establishing the updated system of the integrated underground space map. In addition, through the verification of the automatically updated underground structure data based on the standard format, the reliability of the data can be assured. This format is expected to contribute to the improved utilization of the integrated underground space map in the future.
In spite of relatively low level of radiation dose used at dental clinics, long term exposure may be harmful, so radiation workers at dental clinics must be well aware of its danger. This study was radiation safety management by dental hygienists in order to take preventive measures for dental hygienists and suggest ideas to develop radiation safety training programs. For this, we contacted dental hygienists working at the local dental clinics for 4 months from December of 2003 to march of 2004 and obtained the following findings. 1. Regarding the intraoral radiographic method, the average daily photographing frequency of standard films stood at one to five pieces (47.5%), and the average weekly photographing frequency of digital radiation medicine stood at less than one piece (69.8%), and the average weekly photographing frequency of bitewing films stood at less than one piece (67.7%), and and the average weekly photographing frequency of occlusal films stood at less than one piece (95.5%), and the dentistries whose average weekly photographing frequency of pediatric films stood at one to five pieces accounted for 47.1 percent. 2. Regarding the extraoral radiographic method, the average weekly photographing frequency of panorama film stood at one to five pieces (63.7%), and less than one piece (20.9%), the average weekly photographing frequency of cephalometric film stood at less than one piece (72.3%), and one to five pieces (20.1%). 3. Concerning the radiation safety management training program, only 18.7% of total 278 surveyed attended the training progra., Attendance tendency of the training program by general characteristics showed statistically significant difference according to age (p<0.01), working experience (p<0.001), and marital status (p<0.01). 4. When asked about the protective equipments against radiation exposure, 40.6% of them said "modest", and 71.1% appeared equipped with led apron as a protective tool.
Cancer registries help to establish and maintain cancer incidence reporting system, serve as a resource for investigation of cancer and its causes, and provide information for planning and evaluation of preventive and control programs. However, their wider role in directly enhancing oncology drug access has not been fully explored. We examined the value of cancer registries in oncology drug access in the Asia-Pacific region on three levels: (1) specific registry variable types; (2) macroscopic strategies on the national level; and (3) a regional cancer registry network. Using literature search and proceedings from an expert forum, this paper covers recent cancer registry developments in eight economies in the Asia-Pacific region - Australia, China, Hong Kong, Malaysia, Singapore, South Korea, Taiwan, and Thailand - and the ways they can contribute to oncology drug access. Specific registry variables relating to demographics, tumor characteristics, initial treatment plans, prognostic markers, risk factors, and mortality help to anticipate drug needs, identify high-priority research area and design access programs. On a national level, linking registry data with clinical, drug safety, financial, or drug utilization databases allows analyses of associations between utilization and outcomes. Concurrent efforts should also be channeled into developing and implementing data integrity and stewardship policies, and providing clear avenues to make data available. Less mature registry systems can employ modeling techniques and ad-hoc surveys while increasing coverage. Beyond local settings, a cancer registry network for the Asia-Pacific region would offer cross-learning and research opportunities that can exert leverage through the experiences and capabilities of a highly diverse region.
The sustainability of conventional agriculture which is characterized by input dependent and ecologically simplified food production system is vague. Chemicals and present practices used in agriculture are not only costly but also have widespread implications on human and animal health, food quality and safety and environmental quality. Thus there is a need for alternative farming practices to sustain food production for the escalating population and conserve environment for future generations. The present research scenario in the area of plant microbe interactions for maintaining sustainable agriculture suggests that the level of internal regulation in agro-ecosystems is largely dependent on the level of plant and microbial diversity present in the soil. In agro-ecosystems, biodiversity performs a variety of ecological services beyond the production of food, including recycling of nutrients, regulation of microclimate and local hydrological processes, suppression of undesirable organisms and detoxification of noxious chemicals. Controlling the soil microflora to enhance the predominance of beneficial and effective microorganisms can help improve and maintain soil chemical and physical properties. The role of beneficial soil microorganisms in sustainable productivity has been well construed. Some plant bacteria referred to as plant growth-promoting rhizobacteria (PGPR) can contribute to improve plant growth, nutrient uptake and microbial diversity when inoculated to plants. Term PGPR was initially used to describe strains of naturally occurring non-symbiotic soil bacteria have the ability to colonize plant roots and stimulate plant growth PGPR activity has been reported in strains belonging to several other genera, such as Azotobacter, Azospirillum, Arthrobacter Bacillus, Burkhokderia, Methylobacterium, and Pseudomonas etc. PGPR stimulate plant growth directly either by synthesizing hormones such as indole acetic acid or by promoting nutrition, for example, by phosphate solubilization or more generally by accelerating mineralization processes. They can also stimulate growth indirectly, acting as biocontrol agents by protecting the plant against soil borne fungal pathogens or deleterious bacteria. Present review focuses on some recent developments to evolve strategies for better biotechnological exploitation of PGPR's.
Journal of agricultural medicine and community health
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v.38
no.2
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pp.130-141
/
2013
Objectives: The purpose of this study was to reconsider the necessity of stroke-related educational programs by investigating early symptoms of stroke that emergency medical technicians (EMTs) may experience. Methods: An interview survey was carried out, targeting all EMTs 298 people who were working at 119 fire safety centers and local units in Jeollabuk-do province, from April 1 to 30, 2011. An interviewer administered questionnaire was used to obtain data on ETMs' demographic characteristics, educational level on stroke, and awareness level about early symptoms of stroke and treatment-related characteristics of stroke patients. Results: The results showed that 63.2% of those surveyed had completed the required educational programs on stroke during the past year. The level of awareness about early symptoms of stroke and assessment of stroke patients' condition was relatively high for women, those who were 30 years under, low position people, emergency service practitioners, emergency medical technicians, and people who have completed education, respectively. It was also turned out that 82.8% of those surveyed took stroke patients to the nearest hospitals first so that they could receive appropriate treatment. The level of awareness about early symptoms of stroke and assessment of stroke patients' condition in people who have completed education were higher than non-complete. The level of awareness about early symptoms of stroke was positively correlated with confidence, satisfaction and appropriateness in treatment of stroke patients. Conclusions: These results strongly suggest that it is necessary to operate specialized educational programs to enhance EMTs' appropriate awareness of the early symptoms of stroke and assessment of stroke patient's condition.
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