• The Journal of Korean Physical Therapy
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• v.15 no.1
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• pp.155-170
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• 2003

Lumbar segmental instability is considered to represent a significant sub-group within the chronic low back pain population. This condition has a unique clinical presentation that displays its symptoms and movement dysfunction within the neutral zone of the motion segment. The loosening of the motion segment secondary to injury and associated dysfunction of the local muscle system renders it biomechanically vulnerable in the neutral zone. There in evidence of muscle dysfunction related to the control of the movement system. There is a clear link between reduced proprioceptive input, altered slow motor unit recruitment and the development of chronic pain states. Dysfunction in the global and local muscle systems in presented to support the development of a system of classification of muscle function and development of dysfunction related to musculoskeletal pain. The global muscles control range of movement and alignment, and evidence of dysfunction is presented in terms of imbalance in recruitment and length between the global stability muscles and the global mobility muscles. The local stability muscles demonstrate evidence of failure of aeequate segmental control in terms of allowing excessive uncontrolled translation or specific loss of cross-sectional area at the site of pathology Motor recruitment deficits present as altered timing and patterns of recruitment. The evidence of local and global dysfunction allows the development of an integrated model of movement dysfunction. The clinical diagnosis of this chronic low back pain condition is based on the report of pain and the observation of movement dysfunction within the neutral zone and the associated finding of excessive intervertebral motion at the symptomatic level. Four different clinical patterns are described based on the directional nature of the injury and the manifestation of the patient's symptoms and motor dysfunction. A specific stabilizing exercise intervention based on a motor learning model in proposed and evidence for the efficacy of the approach provided.

• Journal of Dental Anesthesia and Pain Medicine
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• v.21 no.3
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• pp.245-252
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• 2021

Background: The aim of this study was to compare the local anesthetic effect of tramadol with that of lignocaine in the extraction of immobile (grade 0) maxillary first molars. Methods: This was a randomized, double-blind, equally balanced, controlled trial conducted on a sample population of 116 patients. The patients were randomly divided into two groups: group A (control) and group B (study). Group A and group B participants received 1.8 ml of 2% lignocaine without adrenaline and 1.8 ml of 5% tramadol, respectively through the supra-periosteal infiltration technique before extraction. Intraoperative pain was recorded on the Visual Analog Scale (VAS) and was evaluated using two unpaired t-tests. Results: Intraoperative pain was evaluated in both the control and study groups. In the control group, the mean VAS score was 0.71 ± 0.81, while in the study group, the mean intraoperative VAS score was 1.21 ± 0.86, with the difference between the two mean values being statistically significant (P = 0.001). Conclusion: Tramadol has a less potent local anesthetic effect than lignocaine. As a higher dose of tramadol is required to obtain the desired anesthetic effect, it should be used as a supplement to lignocaine in extensive surgical procedures. It can also be used in patients allergic to lignocaine.

• Journal of Dental Anesthesia and Pain Medicine
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• v.21 no.4
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• pp.337-344
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• 2021

Background: The primary indication for using long-acting anesthetics in dentistry is extensive dental procedures that require pulpal anesthesia beyond 90 min and management of postoperative pain. Ropivacaine is an amide local anesthetic that is available at various concentrations with inherent vasoconstrictive properties at low concentrations. Ropivacaine has a 75% greater margin of safety than bupivacaine. Ropivacaine can be a good alternative to bupivacaine as a local anesthetic in dental implant surgery as it provides a longer duration of both pulpal and soft tissue anesthesia after mandibular nerve block and lowers CNS and cardiovascular toxicity. This study aimed to evaluate and compare the clinical efficacy of ropivacaine and lignocaine for implant surgery anesthesia. Methods: Fifteen patients with bilateral edentulous sites indicated for implant placement were recruited for this study. Patients aged 20-60 years of both sexes were randomly recruited. Thirty implant placements were performed in the test and control groups using ropivacaine and lignocaine with adrenaline as local anesthetics, respectively. Results: The results were analyzed statistically. The duration of anesthesia was significantly higher in the test group than in the control group. Ropivacaine was found to be superior to lignocaine in terms of the quality of anesthesia. The comparison of mean visual analog scale scores showed ropivacaine to have better anesthetic and analgesic effects than the control group. Conclusion: Ropivacaine 0.75% provides a significantly longer duration of anesthesia than lignocaine 2% with adrenaline. Ropivacaine 0.75% decreased intraoperative and postoperative analgesia compared to lignocaine 2% with adrenaline. Hence, ropivacaine 0.75% can be used as an alternative to lignocaine in implant surgeries and other intraoral surgical procedures that require a longer duration of anesthesia and analgesia.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.2
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• pp.219-229
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• 2020

Objective: Considering the physiological and clinical importance of leptin receptor (LEPR) in regulating obesity and the fact that porcine LEPR expression is not known to be controlled by lncRNAs and miRNAs, we aim to characterize this gene as a potential target of SSC-miR-323 and the lncRNA TCONS_00010987. Methods: Bioinformatics analyses revealed that lncRNA TCONS_00010987 and LEPR have SSC-miR-323-binding sites and that LEPR might be a target of lncRNA TCONS_00010987 based on cis prediction. Wild-type and mutant TCONS_00010987-target sequence fragments and wild-type and mutant LEPR 3'-UTR fragments were generated and cloned into pmiRRB-REPORT^TM-Control vectors to construct respective recombinant plasmids. HEK293T cells were co-transfected with the SSC-miR-323 mimics or a negative control with constructs harboring the corresponding binding sites and relative luciferase activities were determined. Tissue expression patterns of lncRNA TCONS_00010987, SSC-miR-323, and LEPR in Anqing six-end-white (AQ, the obese breed) and Large White (LW, the lean breed) pigs were detected by real-time quantitative polymerase chain reaction; backfat expression of LEPR protein was detected by western blotting. Results: Target gene fragments were successfully cloned, and the four recombinant vectors were constructed. Compared to the negative control, SSC-miR-323 mimics significantly inhibited luciferase activity from the wild-type TCONS_00010987-target sequence and wild-type LEPR-3'-UTR (p<0.01 for both) but not from the mutant TCONS_00010987-target sequence and mutant LEPR-3'-UTR (p>0.05 for both). Backfat expression levels of TCONS_00010987 and LEPR in AQ pigs were significantly higher than those in LW pigs (p<0.01), whereas levels of SSC-miR-323 in AQ pigs were significantly lower than those in LW pigs (p<0.05). LEPR protein levels in the backfat tissues of AQ pigs were markedly higher than those in LW pigs (p<0.01). Conclusion: LEPR is a potential target of SSC-miR-323, and TCONS_00010987 might act as a sponge for SSC-miR-323 to regulate LEPR expression.

• International Journal of Automotive Technology
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• v.7 no.5
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• pp.609-618
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• 2006

This paper presents the lateral control of an autonomous vehicle by using a look-ahead sensing system. In look-ahead sensing by an absolute positioning system, a reference lane, constructed by straight lanes or circular lanes, was switched by a segment switching algorithm. To cope with sensor noise and modeling uncertainty, a robust LMI-based $H_{\infty}$ lateral controller was designed by the feedback of lateral offset and yaw angle error at the vehicle look-ahead. In order to verify the safety and the performance of lateral control, a scaled-down vehicle was developed and the location of the vehicle was detected by using an ultrasonic local positioning system. In the mechatronic scaled-down vehicle, the lateral model and parameters are verified and estimated by a J-turn test. For the lane change and reference lane tracking, the lateral controllers are used experimentally. The experimental results show that the $H_{\infty}$ controller is robust and has better performance compared with look-down sensing.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.11
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• pp.2862-2868
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• 1996

A sueueing model is developed and analyzed to evaluate the performance of a local and a remote destination of one multicast connection subject to a simple two-level(binary) feedback-based adaptive rate control scheme. The reate control scheme is a simple extension of the one for point-to-point case. Individual cell loss probabilities at the local and remote destinations are obtained to study the fairness of the adaptive rate control scheme. Numerical results show that this simple adaptive rate control scheme, which is fair when it is applied to a multicast connection consisting of destinations with equal propagation delays, bears bias against remote destination.

• Journal of Electrical Engineering and Technology
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• v.10 no.3
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• pp.1319-1327
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• 2015

As wind power farm (WPF) installations continue to grow, monitoring and controlling large-scale WPFs presents new challenges. In this paper, a hierarchical network architecture is proposed in order to provide remote monitoring and control of large-scale WPFs. The network architecture consists of three levels, including the WPF comprised of wind turbines and meteorological towers, local control center (LCC) responsible for remote monitoring and control of wind turbines, and a central control center (CCC) that offers data collection and aggregation of many WPFs. Different scenarios are considered in order to evaluate the performance of the WPF communications network with its hierarchical architecture. The communications network within the WPF is regarded as the local area network (LAN) while the communication among the LCCs and the CCC happens through a wide area network (WAN). We develop a communications network model based on an OPNET modeler, and the network performance is evaluated with respect to the link bandwidth and the end-to-end delay measured for various applications. As a result, this work contributes to the design of communications networks for large-scale WPFs.

• Journal of information and communication convergence engineering
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• v.8 no.6
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• pp.702-708
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• 2010

This paper proposes a novel linearization method for Takagi.sugeno (TS) fuzzy model. A T-S fuzzy controller consists of linear controllers based on local linear models and the local linear controllers cannot be designed independently because of overall stability conditions which are usually conservative. To use linear control theories easily for T-S fuzzy system, the linearization of T-S fuzzy model is required. However, The linearization of T-S fuzzy model is difficult to be achieved by using existing linearization methods because fuzzy rules and membership functions are included in T-S fuzzy models. So, a new linearization method is proposed for the T-S fuzzy system based on the idea of T-S fuzzy state transformation. For the T-S fuzzy system linearized with uncertainties, a robust optimal controller with the robustness of sliding model control(SMC) is designed.

• Journal of The Institute of Information and Telecommunication Facilities Engineering
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• v.10 no.1
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• pp.7-13
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• 2011

Matrix multiplication is a fundamental operation of linear algebra and arises in many areas of science and engineering. This paper introduces an efficient parallel matrix multiplication scheme on N ${\times}$ N mesh-connected SIMD array processor, called multiple hierarchical SIMD architecture (HMSA). The architectural characteristic of HMSA is the hierarchically structured control units which consist of a global control unit, N local control units configured diagonally, and $N^2$ processing elements (PEs) arranged in an N ${\times}$ N array. PEs are communicating through local buses connecting four adjacent neighbor PEs in mesh-torus networks and global buses running across the rows and columns called horizontal buses and vertical buses, respectively. This architecture enables HMSA to have the features of diagonally indexed concurrent broadcast and the accessibility to either rows (row control mode) or columns (column control mode) of 2D array PEs alternately. An algorithmic mapping method is used for performance evaluation by mapping matrix multiplication on the proposed architecture. The asymptotic time complexities of them are evaluated and the result shows that paralle matrix multiplication on HMSA can provide significant performance improvement.

• Journal of Communications and Networks
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• v.16 no.4
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• pp.371-377
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• 2014

Localized topology control is attractive for obtaining reduced network graphs with desirable features such as sparser connectivity and reduced transmit powers. In this paper, we focus on studying how to prolong network lifetime in the context of localized topology control for wireless multi-hop networks. For this purpose, we propose an energy efficient localized topology control algorithm. In our algorithm, each node is required to maintain its one-hop neighborhood topology. In order to achieve long network lifetime, we introduce a new metric for characterizing the energy criticality status of each link in the network. Each node independently builds a local energy-efficient spanning tree for finding a reduced neighbor set while maximally avoiding using energy-critical links in its neighborhood for the local spanning tree construction. We present the detailed design description of our algorithm. The computational complexity of the proposed algorithm is deduced to be O(mlog n), where m and n represent the number of links and nodes in a node's one-hop neighborhood, respectively. Simulation results show that our algorithm significantly outperforms existing work in terms of network lifetime.