• Title/Summary/Keyword: local changes

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Effect of Disodium Fumarate on In vitro Rumen Fermentation of Different Substrates and Rumen Bacterial Communities as Revealed by Denaturing Gradient Gel Electrophoresis Analysis of 16S Ribosomal DNA

  • Mao, S.Y.;Zhang, G.;Zhu, W.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.4
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    • pp.543-549
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    • 2007
  • Two experiments were conducted to investigate the effects of disodium fumarate on the in vitro rumen fermentation profiles of different substrates and microbial communities. In experiment 1, nine diets (high-forage diet (forage:concentrate, e.g. F:C = 7:3, DM basis), medium-forage diet (F:C = 5:5, DM basis), low-forage diet(F:C = 1:9, DM basis), cracked corn, cracked wheat, soluble starch, tall elata (Festuca elata), perennial ryegrass and rice straw) were fermented in vitro by rumen microorganisms from local goats. The results showed that during 24 h incubations, for all substrates, disodium fumarate increased (p<0.05) the gas production, and tended to increase (p<0.10) the acetate, propionate and total VFA concentration and decrease the ratio of acetate to propionate, whereas no treatment effect was observed for the lactate concentration. The apparent DM loss for tall elata, perennial ryegrass and rice straw increased (p<0.05) with the addition of disodium fumarate. With the exception of tall elata, perennial ryegrass and rice straw, disodium fumarate addition increased the final pH (p<0.05) for all substrates. In experiment 2, three substrates (a high-forage diet, a medium-forage diet and a high concentrate diet) were fermented by mixed rumen microbes in vitro. A polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) technique was applied to compare microbial DNA fingerprints between substrates at the end of 24 h incubation. The results showed that when Festuca elata was used as substrate, the control and disodium fumarate treatments had similar DGGE profiles, with their similarities higher than 96%. As the ratio of concentrate increased, however, the similarities in DGGE profiles decreased between the control and disodium fumarate treatment. Overall, these results suggest that disodium fumarate is effective in increasing the pH and gas production for the diets differing in forage: concentrate ratio, grain cereals and soluble starch, and in increasing dry matter loss for the forages (tall elata, perennial ryegrass and rice straw) in vitro, whereas its effect on changes of ruminal microbial community may largely depend on the general nature of the substrate.

Salivary Her2/neu Levels in Differentiation of Oral Premalignant Disorders and Oral Squamous Cell Carcinomas

  • Varun, Chopra;Dineshkumar, Thayalan;Jayant, VS;Rameshkumar, Annasamy;Rajkumar, Krishnan;Rajashree, Padmanaban;Mathew, Jacob;Arunvignesh, Rajendran K
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5773-5777
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    • 2015
  • Background: Oral squamous cell carcinoma (OSCC) is thought to develop from precancerous dysplastic lesions through multistep processes of carcinogenesis involving activation of oncogenes and loss of tumor suppressor genes. The human epidermal growth factor receptor 2 (Her-2/neu [erbB-2]), a cell membrane glycoprotein, is a growth factor receptor that has receptor tyrosine kinase activity. Her2/neu activation plays a central role in cell proliferation and survival. It has been shown that overexpression of Her2/neu increases the rate of cell division and growth, leading to precancerous changes. The aim of the present study was to compare the serum and salivary Her2/neu levels between cases with premalignant and malignant oral lesions. Materials and Methods: Fasting blood samples and unstimulated saliva by passive drooling were collected from three groups of healthy control (n=20), premalignant disorder (PMD) (n=20) and OSCC (n=25) subjects. The HER2 extracellular domain (HER2 ECD) levels were measured using ELISA. Results: The levels of serum Her2/neu showed no significant differences between any of the groups but on the other hand salivary Her2/neu levels were found to be significantly (p<0.05) higher when compared between control (median 68.7 pg/ml, range: 21.5 - 75.8) and OSCC (median 145.6 pg/ml, range: 45.1-191.1). A similar trend was observed when comparing between PMD (median 43.3, range: 22.1 -94.7) and OSCC with a statistical significance of p<0.05. Conclusions: Our study provided evidence of increased salivary Her2/neu in OSCC when compared to PMD and control which was not the case for serum levels. This suggests that probably Her2/neu is not highly amplified as in breast cancer so as to be reflected in serum. Since saliva is in local vicinity of the OSCC, even a mild increase might be mirrored. On the whole, this study proposes Her2/neu as marker for distinguishing premalignant and malignant conditions.

A Study on Hybrid Expressed in Modern Fashion - Focusing on the End of 1990s - (현대패션에 표현된 하이브리드 경향 연구 - 1990년대 후반을 중심으로 -)

  • 임영자;한윤숙
    • Journal of the Korean Society of Costume
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    • v.51 no.5
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    • pp.113-134
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    • 2001
  • This study was carried out with an objective to prepare the framework of conformity for the 21st century modern fashion, which is interactive with mankind, based on a position that the 21st century contemporary fashion with its amalgamating trend of diversified artistic forms may not be elucidated on a standpoint centering on one certain modality. The hybrid fashion trend of historical modality which provides freedom and satisfaction in creation of an individuals expressive power in expressing true desire of mans inside through man-centered thought of the times has made multifarious motives of the past and present fragmentary. It thus extracts inner divisions and the concept of consolidation through three-dimensional form. Modern fashion is newly interpreted by the material and details of high technologies. and is harmonized by mix and match with various expressions. By having it, it is being expressed together with many types of dresses and ornaments. Modern fashion is being expressed together with many types of dresses and ornaments by new interpretations with the material and details of high technologies and by being harmonized with mix and match with various expressions. The hybrid fashion design trend of regional elements formed by stimuli and contacts of diverse local culture by globalization of network that was achieved by scientific technologies of the contemporary information society has disintegrated varied boundaries in the conventional culture by the latest communication technology-new media on the basis of newly created culture. The fact that regional elements could be expressed as if they were interrelated without each being deprived of originality may be explained with an interpretation on pluralism. The hybrid fashion design trend of cultural aspect, which manifests in the background of scientific technological culture as it transcends the societal-cultural boundaries based on the de-centralization theory of Frederic Jameson, has supplemented the imperfect meanings through conversional correlation with other forms and internal program changes. The middle stratal and polyhedral characteristics are seen as each cultural element is dismantled and reassembled by application of 'multiple-time point expression'. Design forming method is not to bring destruction from outside, but to embrace instability and chaos through radical dismantling of the inside. and to pursue diversity and openness. Thus. it is implemented by an approach that takes the role of design process. In communication of discontinuity, continuity was dismantled through forms of mixing, overlap, perversion, insertion and coincidence.

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A Feasibility Study on the Cultivation of Tropical Fruit in Korea: Focused on Mango (FTA 시대 국내 열대과일 재배의 타당성 연구 : 망고를 중심으로)

  • Ji, Seong-Tae;Youm, Jung-Won;Yoo, Ju-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.252-263
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    • 2018
  • In this research, we performed a SWOT analysis to analyze the feasibility of cultivating tropical fruits in Korea, using the mango as a case study. The opportunities for domestic tropical fruit (mango) cultivation are that the domestic cultivation environment is improving due to global warming, the consumer market is expanding due to the increase in domestic demand, and some local governments are supporting the cultivation of tropical fruits as a new high-income crop. The strengths are that it is possible to produce high quality fresh fruits in Korea and that they are still distributed in small quantities, so they can be differentiated from imported ones. There are regular customers and the mango is recognized as a medicinally functional fruit. The threats are that the price competitiveness of imported goods is likely to be further strengthened due to the implementation of the FTA and that it is difficult to cope with the unpredictable climate changes, such as heavy snowfall and extremely cold weather. The weak points are that the initial investment cost is high, the operating costs such as heating bills are also very high, and there is no supply system for the chemicals, fertilizers and cultivation technology required for tropical fruits. In order for tropical fruits such as mangoes to become major fruits, we must make full use of these strengths and opportunities while, at the same time, complementing the weaknesses and eliminating the threats in the value chain.

A Trend Analysis of Agricultural and Food Marketing Studies Using Text-mining Technique (텍스트마이닝 기법을 이용한 국내 농식품유통 연구동향 분석)

  • Yoo, Li-Na;Hwang, Su-Chul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.10
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    • pp.215-226
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    • 2017
  • This study analyzed trends in agricultural and food marketing studies from 1984 to 2015 using text-mining techniques. Text-mining is a part of Big-data analysis, which is an effective tool to objectively process large amounts of information based on categorization and trend analysis. In the present study, frequency analysis, topic analysis and association rules were conducted. Titles of agricultural and food marketing studies in four journals and reports were used for placing the analysis. The results showed that 1,126 total theses related to agricultural and food marketing could be categorized into six subjects. There were significant changes in research trends before and after the 2000s. While research before 2000s focused on farm and wholesale level marketing, research after the 2000s mainly covered consumption, (processed)food, exports and imports. Local food and school meals are new subjects that are increasingly being studied. Issues regarding agricultural supply and demand were the only subjects investigated in policy research studies. Interest in agricultural supply and demand was lost after the 2000s. A number of studies after the 2010s analyzed consumption, primarily consumption trends and consumer behavior.

Effects of local cold application on tissue & peripheral oxygen saturation, peripheral blood flow, skin temperature, and body temperature of healthy adult (국소적 냉 요법이 정상 성인의 조직과 말초의 산소포화도, 말초 혈류, 피부 온도, 체온에 미치는 효과)

  • Kim, Seung Ok;Shin, Yong Soon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.127-136
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    • 2020
  • Purpose: This study aimed to establish a basis for application time and cold therapy interval by checking the physiological changes after applying a cold-gel and ice pack, commonly applied to cold therapy, and after passive rewarming. Method: A total of 22 healthy adults used cold-gel packs and ice packs in a Randomized control group repeated measurement study, and passive rewarming was performed for 40 minutes after 30 minutes of cold therapy. After applying to the right axilla, StO2, SpO2, peripheral blood flow, skin and body temperature were measured 15 times every 5 minutes. Result: In the cold-gel pack group, StO2 decreased from 69.43% to 61.06% after 30 minutes application, and in the ice pack group, StO2 decreased from 67.66% to 64.80% (p <001). In the cold-gel pack group, skin temperature decreased from 33.57℃ to 29.15℃ after 30 minutes application, and in the ice pack group, skin temperature decreased from 32.64℃ to 28.90℃ (p <.001). Only skin temperature recovered completely after 40 minutes of rewarming. There were insignificant differences between the cold-gel pack and ice pack. Conclusion: When applying cold therapy to the axillary, at least 40 minutes for passive rewarming is necessary after 30 minutes of application.

Associations of dietary intake and metabolic syndrome risk parameters in Vietnamese female marriage immigrants in South Korea: The KoGES follow-up study

  • Yang, Hyesu;Kim, Hyesook;Kim, Ji-Myung;Chung, Hye Won;Chang, Namsoo
    • Nutrition Research and Practice
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    • v.10 no.3
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    • pp.313-320
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    • 2016
  • BACKGROUND/OBJECTIVES: This study was conducted to compare the overall changes in dietary intake and metabolic syndrome risk parameters in Vietnamese marriage-based female immigrants over time. SUBJECTS/METHODS: The subjects of this study were 581 Vietnamese marriage-based female immigrants, who were recruited from local clinical centers in Korea. Baseline data were collected from 2006-2011 and the follow-up data were collected from 2012-2014. Dietary food intake was assessed by a 1-day 24-hour recall method. RESULTS: Compared to the baseline, the mean body weight, body mass index, waist circumference, high density lipoprotein (HDL)-cholesterol, systolic blood pressure and diastolic blood pressure increased while the fasting blood sugar, triglycerides and low density lipoprotein-cholesterol decreased at follow-up. The total consumption of foods such as vegetables/fruits/seaweeds/mushrooms, oil and fat, and eggs decreased during the follow-up period, whereas the consumption of sugars, beverages and meats increased. Partial correlation between the rate of change [(Follow-up - Baseline) / Baseline ${\times}100$] in metabolic syndrome risk parameters and food intake after controlling for confounding factors showed that the waist circumference was positively correlated with either the total plant food intake (r = 0.1042, P = 0.0129) or the total food intake (r = 0.0880, P = 0.0359). The plasma levels of total cholesterol (r = -0.1918, P = 0.0289) and HDL-cholesterol (r = -0.1424, P = 0.0007) were negatively correlated with the percentage of total intake from plant food, and HDL-cholesterol levels were positively correlated with the intake of total animal food (r = 0.0980, P = 0.0217). The serum C-reactive protein levels were positively correlated with the total intake of animal food (r = 0.2374, P < 0.0001) or the percentage of total intake from animal food (r = 0.1346, P = 0.0016). CONCLUSIONS: These results suggest that the change rate of dietary intake such as total plant food or animal food is associated with the change rates of metabolic syndrome risk parameters.

Finite Element Analysis of Flow and Water Quality in the New Harbor Site (신항만부지에서의 유동 및 수질에 관한 유한요소해석)

  • Ahn, Do-Kyung;Lee, Joong-Woo
    • Journal of Navigation and Port Research
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    • v.26 no.1
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    • pp.137-145
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    • 2002
  • Water flow simulations for environmental problems often require local detailed analyses for better understanding and accurate prediction of the fate of pollutant in water bodies. This study deals with the development and application of a two-dimensional flow an dispersion model to the coastal water area to find out possible changes due to the wide port development plan. As far as the spatial discretization is concerned, the finite element method is attractive because of its flexibility and ability to naturally treat complex coastal geometries. The model uses finite element theory and the Galerkin weighted-residual approach as its basis. Developed model is applied to the Busan New harbor Construction site. Results from the model were compared with the measured water level and flows in four stations. The flow pattern by the model shows to be similar to the observed data away from the construction site where the flow is not affected. From the simulation results, it is concluded that the model may be useful for numerous other studies for planning and management purposes, especially flow and pollution dispersion in the coastal water bodies where the flow is so complicated.

Shoes from Pinet to the Present

  • June, Swann
    • Proceedings of the Korea Society of Costume Conference
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    • 2001.08a
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    • pp.11-13
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    • 2001
  • For those unfamiliar with the shoe world, Pinet (1817-1897) was a contemporary of Worth, the great Parisian couturier. So I look at the glamour shoes and the world of haute couture, and indeed the development of the named designer. That is a concept we are all familiar with now. So it is not easy to comprehend the lack of names for the exquisite work before 1850. Straightway I have to say that the number of noted shoe designers is far fewer than famous dress designers, but I will introduce you to some of them, against the background of contemporary shoe fashions. Franc;ois Pinet was born in the provinces (probably Touraine) in 1817, two years after the end of the Napoleonic Wars. His father, an ex-soldier, settled to shoemaking, a comparatively clean and quiet trade. It had a tradition of literacy, interest in politics, and was known as the gentle craft, which attracted intelligent people. We should presume father would be helped by the family. It was usual for a child to begin by the age of 5-6, tying knots, sweeping up, running errands and gradually learning the job. His mother died 1827, and father 1830 when he was 13, and at the time when exports of French shoes were flooding world markets. He went to live with a master shoemaker, was not well treated, and three years later set out on the tour-de- France. He worked with masters in Tours and Nantes, where he was received as Compagnon Cordonnier Bottier du Devoir as Tourangeau-Ia rose dAmour (a name to prove most appropriate). He went on to Bordeaux, where at 19 he became president of the local branch. In 1841 he went to Paris, and in 1848, revolution year, as delegate for his corporation, he managed to persuade them not to go on strike. By now the shoemakers either ran or worked for huge warehouses, and boots had replaced shoes as the main fashion. In 1855 Pinet at the age of 38 set up his own factory, as the first machines (for sewing just the uppers) were appearing. In 1863 he moved to new ateliers and shop at Rue ParadisPoissoniere 44, employing 120 people on the premises and 700 outworkers. The English Womans Domestic Magazine in 1867 records changes in the boots: the soles are now wider, so that it is no longer necessary to walk on the uppers. There is interest in eastern Europe, the Polonaise boots with rosette of cord and tassels and Bottines Hongroises withtwo rows of buttons, much ornamented. It comments on short dresses, and recommends that the chaussure should correspond to the rest of the toilet. This could already be seen in Pinets boots: tassels and superb flower embroidery on the higher bootleg, which he showed in the Paris Exposition that year. I think his more slender and elegant Pinet heel was also patented then or 1868. I found little evidence for colour-matching: an English fashion plate of 1860 shows emerald green boots with a violetcoloured dress.

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Phased Introduction of the New Transportation System under the Step-by-step Land Development Project (단계적 택지개발사업에 따른 신교통시스템 적정 도입방안 분석)

  • Kim, Tae-Gyun;Lee, Yun-Sang;Jeong, Yeun-Woo
    • Land and Housing Review
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    • v.7 no.3
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    • pp.157-164
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    • 2016
  • Recently, the paradigm of land development has been transformed from the joint development to the step-by-step development due to changes in socio-economic conditions. Nevertheless, the introduction of large-scale transportation facilities such as new transportation system tends to employ the joint development. Although new transportation system is eco-friendly, it occasionally fails at the beginning of the project because of high installation cost. Such phenomenon is caused by not only the system did not reflect the local characteristics but also did not respond to the step-by-step development. Accordingly, in order to introduce transportation system rationally, introducing new methods corresponding to the step-by-step development should be sought. In this study, we assumed that large-scaled land development site be achieved step-by-step development. and suggested the need for a phased introduction through benefit-cost analysis. The findings illustrated that the phased introduction shows economic efficiency with 30% increase of B/C compared to the bulk introduction. It also demonstrates that the bulk introduction under step-by-step development is more efficient than the bulk introduction under joint development.