Cervical cancer (CaCx) is the second most fatal cancer contributing to 14% of cancers in Indian females, which account for 25.4% and 26.5% of the global burden of CaCx prevalence and mortality, respectively. Persistent infection with high-risk human papilloma virus (HPV- strains 16 and 18) is the most important risk factor for precursors of invasive CaCx. Comprehensive prevention strategies for CaCx should include screening and HPV vaccination. Three screening modalities for CaCx are cytology, visual inspection with acetic acid, and HPV testing. There is no Indian national policy on CaCx prevention, and screening of asymptomatic females against CaCx is practically non-existent. HPV vaccines can make a major breakthrough in the control of CaCx in India which has high disease load and no organized screening program. Despite the Indian Government's effort to introduce HPV vaccination in the National Immunization Program and bring down vaccine cost, challenges to implementing vaccination in India are strong such as: inadequate epidemiological evidence for disease prioritization, duration of vaccine use, parental attitudes, and vaccine acceptance. This paper reviews the current epidemiology of CaCx and HPV in India, and the current status of HPV vaccination in the country. This article stresses the need for more research in the Indian context, to evaluate interventions for CaCx and assess their applicability, success, scalability and sustainability within the constraints of the Indian health care system.
The sales activity of most of small manufacturing companies is based on orders of buyers. The process of promotion, negotiation, receipt and selection of orders of the manufacturers is closely coupled with the load status of the production lines. The decision on whether to accept an order or not, or the selection of optimal order set among excessive orders is entirely dependent on the schedule of production lines. However, in the real world, since the production scheduling activity is mainly performed by human experts, most of small manufacturers are suffer from being unable to meet due dates, lack of rapid decision on the acceptance of new order. Recently, Internet based Electronic Commerce is recognized as one of the alternatives for strengthening sales power of small and medium companies. However, small and medium manufacturers can't adjust properly to the new environment because they are in short of money, personnel, and technology. To cope with this problem, this paper deals with development of part sales agent coupled with virtual manufacturing in Internet environment that consist of selection agent, advertisement agent, selection agent, negotiation agent, and virtual manufacturing system. This paper develops a time-bounded negotiation mechanism for small and medium manufacturers in agent-based automated negotiation between customers and negotiation agents. Furthermore, to select optimal order set maximized profit, we first formulate the order selection problem with mixed integer programming, but the computation time of IP is not acceptable for real world scale problem. To overcome this problem and dynamic nature of virtual manufacturing, we suggest a genetic algorithm approach, which shows a reasonable computation time for real world case and good incremental problem solving capability.
The Journal of The Korea Institute of Intelligent Transport Systems
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v.13
no.2
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pp.57-67
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2014
In the last decade, various situations were simulated through virtual environment due to rapid improvement of computer capability and technology. Transportation engineering also has adopted the virtual environment facility in order to identify drivers behaviour under various circumstances. This study aims to evaluate driver reactions to the introduction of new ITS interventions at railway crossings (RLX) in driving simulator. Three ITS safety devices were used to figure out how drivers reacted to them. In addition, a survey was conducted to find participants' work load and acceptance of the technology. The ultimate purpose of this paper is to evaluate ITS safety devices in various aspects. Each participant made 3 runs (2 baselines, 1 ITS randomly) for approximately 20 minutes each. The participants answered that current railway crossings did not look safe prior to experiment. They responded that the use of ITS technologies were easy and the technologies were more effective on passive railway crossings.
Purpose: The reconstruction of a soft tissue defect of the heel pad can be challenging. One vital issue is the restoration of the ability of the heel to bear the load of the body weight. Many surgeons prefer to use local flaps or free tissue transfer rather than a skin graft. In this study, we evaluated the criteria for choosing a proper flap for heel pad reconstruction. Methods: In this study, 23 cases of heel pad reconstruction were performed by using the flap technique. The etiologies of the heel defects included pressure sores, trauma, or wide excision of a malignant tumor. During the operation, the location, size and depth of the heel pad defect determined which flap was chosen. When the defect size was relatively small and the defect depth was limited to the subcutaneous layer, a local flap was used. A free flap was selected when the defect was so large and deep that almost entire heel pad had to be replaced. Results: There was only one complication of poor graft acceptance, involving partial flap necrosis. This patient experienced complete recovery after debridement of the necrotic tissue and a split thickness skin graft. None of the other transferred tissues had complications. During the follow-up period, the patients were reported satisfactory with both aesthetic and functional results. Conclusion: The heel pad reconstructive method is determined by the size and soft-tissue requirements of the defect. The proper choice of the donor flap allows to achieve satisfactory surgical outcomes in aesthetic and functional viewpoints with fewer complications.
Journal of the Korea institute for structural maintenance and inspection
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v.26
no.2
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pp.84-91
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2022
This study investigated the behavior of out-of-plane skewed moment connections that were designed as IMFs, as per the Korean standards. A total of 14 finite element models were constructed with the consideration of two types (single- and double-sided connections) and four levels of skew angle (0°, 10°, 20°, and 30°). The results indicated that the skewed connections considered in this study met the acceptance criteria for IMFs given by the codes. However, the load-carrying capacities of skewed connections were decreased as the skew angle increased. For the connection with a skew angle of 30°, the peak load was noted to be 13% less and the energy dissipation capacity could be 26% less than that of non-skewed connection. In addition, because of the skewed nature, the stress distribution in the skewed beam flange near the connection was asymmetric and the stresses were concentrated on the beam inner flange. Column twisting induced by the skewed configuration was very small and negligible in the beam and column combination considered in this study.
The aim of this study was to evaluate the quality characteristics of fresh red paprika treated by electron-beam irradiation at quarantine doses. The initial microbial loads were low with $10^4$ and $10^2$ colony-forming units/g for total aerobic bacteria and coliform, respectively; however, a dose of 1 kGy resulted in load reduction of 1 log cycle. A dose level of more than 1 kGy caused significant decreases in the hardness and carotenoid content parameters. An applied dose level of less than 2 kGy did not affect vitamin C content; however, a decrease of 87-90% was observed after 40-day storage. Samples treated with 2 kGy showed significantly lower acceptance compared to the control, with lower sensory evaluation scores for color and texture. Therefore, e-beam irradiation at dose range of 0.4 and 1 kGy was found to be appropriate for quarantine applications for microbiological control and quality maintenance of paprika.
Kim, Sung Yong;Lee, Cheol Ho;Kim, Na Eun;Cho, Sung Sang;Chung, Woon Ok
Journal of Korean Society of Steel Construction
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v.26
no.6
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pp.511-522
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2014
In this study, an innovative steel stair system is presented which enables rapid erection and high quality control in both residential and office building construction. This system features two lightweight steel stringers of box shape, bolted connections easy to absorb construction tolerance, and stair steps movable transversely (or sliding steps) such that the work space needed for concrete stairway wall could be easily provided. In this type of stairway system, other than providing robust connecting details, ensuring vibration performance is especially important since this system may be vibration-sensitive due to lightweight nature and/or probable low damping. To tackle these issues, a series of full-scale mock-up tests were conducted by using box-shape stringer members with or without concrete-fill. The connection system was shown to be sufficiently stiff and strong, or it remained elastic even under the 160% of service load level. Among the seven stringer alternatives, five exhibited satisfactory vibration performance according to the related North American and European acceptance criteria.
Nutrition label (NL) on the package of processed food provides consumers with a reliable and consistent source of information . It has been considered as a useful aid for food selection and a potent educational tool for nutrition in daily life. Since current nutrition labeling regulation in Korea does not define a format for presenting nutrition information a wide variety of NL format exists in the markers created by individual manufacturers. Development of standard NL format and its registration remain to be the work for the professionals and government officials. However the acceptance and evaluation of NL by the consumers is a very important and necessary process in the development of NL formats. In this study four different formats A, B, C, D were formulated based on currently circulating labels and new U.S.NL. Subjects used for evaluation of these formats were middle -aged highly educated housewives, who and the potential users of NL. Major parameters observed through the questionnare were their nutritional knowledge of RDA, ability of IC(Information Comparison) and CA (Comprehension and Application of informed nutrient contents), as well as their preference to the different formats. The results are summarized as follows. 1) Of the 178 subjects , 89.9% of the middleaged housewives were college graduates. Their nutrition knowledge of RDA were relatively satisfactory showing over 80% correlation on the basic concepts and unit while for numerical value less than 50% correct answer. 2) IC test scores were significantly different among the formats showing the highest values for format A and B which are presented as absolute value and % RDA, respectively. Format C presented as serving size(number of products) showed the lowest score. CA scores were also significantly different, though the increased load of information did not facilitate to increase the consumers comprehension. 3) RDA knowledge test scores and the scores of IA and CA were correlated in format A and D but not in format B and C suggesting % RDA presentation would be more acceptable to the less educated group. 4) For the preference in the aspects of easiness and time-saving format A was the best one then format D supporting the result of IC and CA test. The results of the present study indicate the most useful and preferred format is the simplest format presented as absolute value without RDA, . The secondly preferred format is the new NL format of the US with much information .
Park, Chan-Duk;Lee, Kyu-Hwan;Ryu, Nam-Jae;Lee, Song
Journal of the Korea institute for structural maintenance and inspection
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v.8
no.1
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pp.175-181
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2004
This study is about a section where underground water level occurs at the underground 5m depth by the excavation of the ground, as a stream is adjacent to a excavation section of High Speed Railway ${\bigcirc}{\bigcirc}$ Station construction sections and a reservoir being always full of water is located at the left side of the construction section. Therefore this test is executed for the design and construction of buoyance anchors able to permanently prevent buoyance by the underground water level at working and for the stable construction and permanent smooth maintenance of structures. In this test, bar type anchors are divided according to their length and standard to execute test-anchor test, and In spot test, 9 test-anchors test, proof test to construction process, suitability test and acceptance test are executed 4 times to 9 test-anchors by dividing anchors according to the length of permanent anchor, the outer diameter of bar and boring diameter. Standard motion characteristic centering on load transmission and break mechanism of bar-type anchors for the prevention of buoyance will be showed in the thesis.
Saxena, Shailesh;Khan, Mohammad Zubair;Singh, Ravendra;Noorwali, Abdulfattah
International Journal of Computer Science & Network Security
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v.21
no.11
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pp.345-353
/
2021
Cloud computing represent a new era of computing that's forms through the combination of service-oriented architecture (SOA), Internet and grid computing with virtualization technology. Virtualization is a concept through which every cloud is enable to provide on-demand services to the users. Most IT service provider adopt cloud based services for their users to meet the high demand of computation, as it is most flexible, reliable and scalable technology. Energy based performance tradeoff become the main challenge in cloud computing, as its acceptance and popularity increases day by day. Cloud data centers required a huge amount of power supply to the virtualization of servers for maintain on- demand high computing. High power demand increase the energy cost of service providers as well as it also harm the environment through the emission of CO2. An optimization of cloud computing based on energy-performance tradeoff is required to obtain the balance between energy saving and QoS (quality of services) policies of cloud. A study about power usage of resources in cloud data centers based on workload assign to them, says that an idle server consume near about 50% of its peak utilization power [1]. Therefore, more number of underutilized servers in any cloud data center is responsible to reduce the energy performance tradeoff. To handle this issue, a lots of research proposed as energy efficient algorithms for minimize the consumption of energy and also maintain the SLA (service level agreement) at a satisfactory level. VM (virtual machine) consolidation is one such technique that ensured about the balance of energy based SLA. In the scope of this paper, we explore reinforcement with fuzzy logic (RFL) for VM consolidation to achieve energy based SLA. In this proposed RFL based active VM consolidation, the primary objective is to manage physical server (PS) nodes in order to avoid over-utilized and under-utilized, and to optimize the placement of VMs. A dynamic threshold (based on RFL) is proposed for over-utilized PS detection. For over-utilized PS, a VM selection policy based on fuzzy logic is proposed, which selects VM for migration to maintain the balance of SLA. Additionally, it incorporate VM placement policy through categorization of non-overutilized servers as- balanced, under-utilized and critical. CloudSim toolkit is used to simulate the proposed work on real-world work load traces of CoMon Project define by PlanetLab. Simulation results shows that the proposed policies is most energy efficient compared to others in terms of reduction in both electricity usage and SLA violation.
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