• Journal of Korea Association of Health Promotion
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• v.2 no.1
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• pp.93-104
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• 2004

Purpose : This study was conducted to understand the health status and health behaviors of preschoolers to provide baseline data for developing health promotion programs. Method 'Parents of children attending day-care centers and guardians of preschoolers were recruited for the study. Data were collected from June to August2002 using a structured questionnaire. Result . Among 754 preschoolers, 17,3% were overweight, while 18.2% were underweight, while 15.9% and 23.2% were overweight and underweight respectively, among 85 children living with guardians. The most frequent infectious diseases that children have had previously were hand-foot-mouth disease, chicken pox, and measles. Current health conditions that children have frequently are respiratory disease and atopic dermatitis for bother groups. Only 54%-61% brush their teeth everyday at bedtime, 49%-54% wash their hands every time after returning home, 4.5%-8.8%wear bicycle helmets, 9,3%-11.1% use a child car seat, and 3.5%-8.1% eat fruits and vegetables five times a day, Children living with guardians were less likely toper form positive health behaviors compared with children in day-care centers. Conclusion 'Based on the study results, health professionals could plan and develop health promotion programs to change unhealthy behaviors of preschoolers targeting high-risk groups.

• Journal of fish pathology
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• v.24 no.3
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• pp.269-278
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• 2011

Gene expression of two glyceraldehyde-3-phosphate dehydrogenase (GAPDH) paralogs was examined during Edwardsiella tarda challenge and heavy metal exposures in mud loach (Misgurnus mizolepis; Cypriniformes) kidney and spleen. Transcription of the two mud loach GAPDH paralogs (mlGAPDH-1 and mlGAPDH-2) was significantly modulated by these stimulatory challenges in an isoform-dependent manner. Based on the real-time RT-PCR analysis, the mlGAPDH-2 transcripts were more preferentially induced by E. tarda challenge, whereas the mlGAPDH-1 transcripts were proven to show more inducibility in response to heavy metal exposure using Cd, Cu, Mn and Zn at $5{\mu}M$. Their isoform-specific response patterns were closely in accordance with the TF binding profiles in promoter and intron-1 of the two mlGAPDH isoforms, in which the mlGAPDH-2 has more binding sites for immune-related transcription factors than mlGAPDH-1 while the mlGAPDH-1 possesses exclusively metal responsive elements in its intron. Collectively, the mlGAPDHs are potentially involved in cellular pathways independent of glycolysis and the two GAPDH paralogs might undergo functional diversification or subfunctionalization at least at the transcription level.

• The Journal of Korean Physical Therapy
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• v.24 no.6
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• pp.398-404
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• 2012

Purpose: This is designed to study the effect of weight-support walking training through motor learning on motor functions of children with cerebral palsy, in particular their activity of daily living and balance. Methods: Thirteen children with spastic cerebral palsy, at gross motor function classification system (GMFCS) levels III~IV, underwent treadmill walking training. It used principles of weight support, 4 times a week for 7 weeks, 10 minutes at a time, before and after neurodevelopmental physical therapy. Everyday functions were measured using Functional Independence Measure for Children (Wee-FIM). The ability to keep their balance was measured using electronic measuring equipment from good balance system and the assessment was made before and after the experiment. Results: There were significant differences (p<0.05) between pre and post experiment levels of functional independence in everyday life, in self-care activities, mobility, locomotion and social cognition. With regard to changes in standing balance, there were significant differences before and after the experiment (p<0.05) in GMFCS level III. There was a reduction in the agitation velocity in the x- and y-axes which measures the left-to-right shaking; in GMFCS level IV, velocity moment was reduced. Conclusion: Walking training using a treadmill can help improve the everyday activity and balance in children with spastic cerebral palsy. It can also be served as a useful purpose as a method of intervention in pediatric care.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.2 no.2
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• pp.139-154
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• 1995

The purpose of this study was presented basic data for management of living kidney donor to make bioethical decision. The research subjects were the documents and progress notes of Doctor's and Nurses in medical records related to kidney donation and nephrectomy of 20 kidney donors who received nephretomy at 4 general hospitals in Pusan. The result of this study, a desirable documents to help the living kidney donor might include following : 1st, identification of the donor and the guardian. 2nd, confirmation of the intension of kidney donor which is based on humanity or not and 3rd, a written oath about Nephrectomy. Especially it is more desirable to participate of paramedical personnels such as the religious, the social workers, the counsellors, and etc when assess the motivation of kidney donor and to use of a formulated visual educational materials about renal angiography and nephrectomy which required written consent of kidney donor. Further more, the donor should be educated sufficiently about the kidney itself and procedure for nephrectomy-the anatomical position of kidney, the function of the kidney, the operative maneaver, pre and post operative complication, the prevention of the complication, the possiblity of rejection phenomenon and loss of the transplanted kidney etc. In conclusion, medical team members for kidney transplantation must suggest not only physical problem but also psychological problem And the educated donor ought to have enough time before a making decision and all these process should be recorded in medical records

• Korean Journal of Ichthyology
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• v.11 no.2
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• pp.139-142
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• 1999

Two specimens of Opistognathus iyonis of Family Opistognathidae were collected for the first time at Chwasari Islands, Yokchi-myon, Tongyong-shi, Kyongsangnam-do, Korea. Specimens were catched by fishing on June and Oct. 1998. Opistognathus iyonis was characterized by having large mouth, big eye located anterior part of the head, large black spot on the dorsal fin and lateral line running close below base of dorsal fin. A new Korean name "Huk-Jom-Hu-Ak-Chi" is proposed for this species.

• Journal of the Korean housing association
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• v.11 no.3
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• pp.29-41
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• 2000

The main object of this research was to study the better housing business by the Architectural Association of Chosun. The Architectural Association of Chosun was founded in 1992 and it influenced great deal on the development of Korean architecture. The Architectural Association of Chosun took the first step in business by holding the Better Housing Plan Competition which was the first housing plan competition in Korea, Also, it meant the enlightenment of better cultural housing. Overall, it can be summarized as follows; 1) It could be considered that the Architectural Association of Chosun was connected with the Japanese Colonial Policy of that time. 2) The Better Housing Plan Competition indicated the way of improving better living condition. 3) Most of the prize-wining works emphasized economical and practical way of housing. 4) The wanted to get out of the old conventional way of hosing. 5) All the plans showed \" the living\" and it meant that \" the living: is the centre of family life which connected the modern housing plan. 6) Western way of life was combined with the conventional style, in other words, modernization of life was derived from the western style. 7) Better housing plan which is more suitable for the Korean weather and environment was not considered. 8) Colonial domination of Japanese style could also be found in housing. Most of the plans used Japanese style as the basic housing style. housing style.

• Child Health Nursing Research
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• v.14 no.2
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• pp.146-154
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• 2008

Purposes: The purposes of this study are to describe the health problems experienced by VLBW premature infants and their health care services utilization during the first year of life Method: Eighteen mothers of VLBW premature infants completed a survey questionnaire, asking socioeconomic/demographic information, health/developmental problems experienced by their infants, and their use of health care services. Results: Of the 18 infants, 78% experienced respiratory problems such as cold/running nose and wheezing during the first year and 33% experienced gastrointestinal problems such as vomiting, diarrhea and constipation. Twelve (67%) infants visited the emergency department at least one time and 10 infants (56%) were hospitalized at least once during their first year of age. Interestingly, infants without chronic lung disease visited the emergency department more than infants without chronic lung disease (p=.213). Infants living in non-disadvantaged neighborhoods were hospitalized more than infants living in disadvantaged neighborhoods (p=.000). Conclusions: Health care providers should initiate educating mothers, particularly those living in disadvantaged neighborhoods, about post-NICU discharge health care needs of their VLBW premature infants while their infants were still in the NICU so that unnecessary visits to the emergency department and rehospitalizations can be possibly prevented.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2008.11a
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• pp.327-331
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• 2008

In Korea, welfare needs brought on by the rapidly growing of elderly population. Also, the senior group with spare time, wealth and health is increasing. Currently, the people have known about needs welfare system for improving quality of life during senescence personally and socially. In addition to the senior friendly industry, having distinction with simple approach medical services, will be great expanding after 2010. And there will be a new welfare services plan supporting long term care insurance for senior citizens. But we don't have prepared systematically organized senior friendly industry and products yet. So, the purpose of the study is to analyze systematically the classification characteristics of the senior friendly products according to the difficulty of daily living for senior citizens. Above all, the study finds out the senior friendly products characteristics according to the consumer's various situations about health and housing space. Therefore the result of the study reveals that the simulation guidelines for choosing the products depend on the customer's needs are essential and useful to improve senior friendly industry. And the post evaluation data of senior friendly products would be put to practical use in the industry.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2008.11a
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• pp.92-95
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• 2008

As society ages increasingly, maintaining an independent lifestyle at home becomes an important issue for older people. The elderly themselves demand an independent lifestyle despite their health status and living arrangements. The purpose of this study is to provide basic guidelines for the elderly housing through the analysis of seniors' housing behavior. The total of 438 residents take part in the questionnaire survey research through the quota sampling method grouped by age (60-64 group, 65-69 group, 70-74 group, over 75 group). The results are as follows. (1) Seniors' subjective physical and functional status is not differed one age group from the others, but it is differed by the sex. (2) Seniors spend more than three hours on watching TV. The male spend more time on information search, while the female on the house chores. (3) The older use the bedroom more than the younger. Living rooms are more frequently used among the young old and the residents live in the apartment houses. (4) More than half senior use a sofa in the living room, a table in the dining room, and a bed in the bedroom. The young old and the apartment residents use such furniture more than the other groups.

• BMB Reports
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• v.51 no.10
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• pp.526-531
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• 2018

Protein-Protein Interactions (PPIs) play essential roles in diverse biological processes and their misregulations are associated with a wide range of diseases. Especially, the growing attention to PPIs as a new class of therapeutic target is increasing the need for an efficient method of cell-based PPI analysis. Thus, we newly developed a robust PPI assay (SeePPI) based on the co-translocation of interacting proteins to the discrete subcellular compartment 'processing body' (p-body) inside living cells, enabling a facile analysis of PPI by the enriched fluorescent signal. The feasibility and strength of SeePPI (${\underline{S}}ignal$ ${\underline{e}}nhancement$ ${\underline{e}}xclusively$ on ${\underline{P}}-body$ for ${\underline{P}}rotein-protein$ ${\underline{I}}nteraction$) assay was firmly demonstrated with FKBP12/FRB interaction induced by rapamycin within seconds in real-time analysis of living cells, indicating its recapitulation of physiological PPI dynamics. In addition, we applied p53/MDM2 interaction and its dissociation by Nutlin-3 to SeePPI assay and further confirmed that SeePPI was quantitative and well reflected the endogenous PPI. Our SeePPI assay will provide another useful tool to achieve an efficient analysis of PPIs and their modulators in cells.