• 약학회지
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• 제44권6호
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• pp.499-504
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• 2000

We previously demonstrated that 6-paradol, a compound structurally related to capsaicin, showed to produce prolonged analgesia in experimental animals. The effects of 6-paradol on the release of adenosine were investigated in the rat spinal cord synaptosomes by high performance liquid chromatography. In the presence of $Ca^{++}$, adenosine was released from synaptosomes of rat spinal cord by 6-paradol and capsaicin in a dose dependent manner. Nifedifine, L-type voltage sensitive calcium channel blocker, was found to be ineffective in releasing adenosine by $10\;{\mu}M$ 6-paradol. After exposure to $10\;{\mu}M$ capsazepine, a novel capsaicin selective antagonist, the level of adenosine evoked by $10\;{\mu}M$ 6-paradol was decreased by 75%, and that evoked by $10\;{\mu}M$ capsaicin was blocked completely. These results suggest that the analgesic effect of 6-paradol might be mediated by the vanilloid (capsaicin) sensitive pathway, or the direct binding to the vanilloid receptor.

• 한국세라믹학회지
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• 제52권1호
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• pp.28-32
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• 2015

In this article, the influence of a hydrolyzed wheat protein retarder on the hydration process, ion concentration in liquid phase, degree of supersaturation, and crystal morphology of plaster was investigated. Furthermore, the retarding mechanism and the strength loss of gypsum were also studied by scanning electron microscopy (SEM). The results indicate that the use of the hydrolyzed wheat protein retarder for plaster achieved a better retarding effect and lower strength loss. The combination of gypsum plaster with the retarder not only decreased the plaster's early hydration rate and prolonged its setting time efficiently, but also militated against the crystal morphology of dihydrate gypsum. For example, the crystal dimensions changed little, but the proportion of needle-shaped crystals decreased. Combination with calcium ions on the surface of dihydrate gypsum crystal nuclei may form a chemisorbed layer, reduce the surface energy of the crystal nuclei, and inhibit the growth of the crystal nuclei of dihydrate gypsum. Consequently, the hydration process of building gypsum becomes greatly extended and is slowed down significantly.

• 한국세라믹학회지
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• 제40권12호
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• pp.1235-1240
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• 2003

포틀랜드 시멘트의 조성범위가 되도록 한 패각-주조분진-전로슬래그계 조합물의 클링커 소성성과 시멘트 광물 생성거동에 대하여 광물상과 미구조 관찰을 중심으로 연구하였다. 이 조합물은 원료의 특성상 융액 생성이 용이하여 시멘트 클링커는 일반 천연 원료를 사용한 경우에 비하여 10$0^{\circ}C$ 정도 낮은 온도에서 생성된다. 조합물 내의 유리산화칼슘은 135$0^{\circ}C$ 이하에서 완전히 소멸되며 alite나 belite와 같은 시멘트 주광물의 합성은 140$0^{\circ}C$ 이하의 온도에서 과다한 유리상의 생성이 없이 완료된다.

• 자원환경지질
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• 제16권3호
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• pp.149-161
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• 1983

경상도(慶尙道) 지역(地域)의 삼기층중(三紀層中)에 배태(胚胎)되어진 산성백토(酸性白土)는 주(主)로 Ca-몽모리로나이트로 구성되며 이의 조성비(組成比)는 95%까지에 이른다. 이에 수반되는 광물(鑛物)은 크리스토발라이트, 석영(石英), 장석(長石), 삼정석광물(三井石鑛物) 및 비결정질(非結晶質)이 있다. 시차열분석(示差熱分析), 적외선 및 전자현미경에 의한 이들의 기본적인 특성(特性)을 기재하였고 물리적성질(物理的性質)을 섭성한계(涉性限界) 및 양이온교환능을 측정기재하였다. 이들 자원(資源)의 이용가능한 용도범위를 고찰하였다.

• 한국식품조리과학회지
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• 제9권2호
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• pp.99-104
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• 1993

This study was carried out in order to develop supplementary foods for infants using Korean foods. Thirty-four different kinds of supplementary foods were developed and fourteen representative ones were selected to be analyzed chemically. The results are as follows: 1. The developed supplementary foods were 34 kinds and divided into 3 stages. First stage is designed for the babies just beginning to eat pureed vegetables and fruits. Second stage combined the nutritional attributes of both vegetables and meat. Third stage featured tender, bite-size pieces of meats and vegetables that appealed to the most mature tastes of basies. 2. In the production of prepared foods; water, milk, vegetable juice, fruit juice, and soy milk were used as the liquid source; rice, rice starch, chestnut, noodle, potatoes, sweet potatoes, rice cakes as the carbohydrate source; fish, meats soybean curd, beans, eggs, chicken, cow liver as the protein source; and vegetables and fruits were used as vitamin & mineral source. 3. The approximate composition range of the products were 10.91∼24.46% carbohydrate, 0.15∼6.06% protein, 0.092∼7% fat, 0.13∼ 1.37% ash, 0.63∼36.34% calcium, 0.092∼0.48% iron and 0.42∼16.36% vitamin C.

• Archives of Pharmacal Research
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• 제28권3호
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• pp.319-324
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• 2005

The present study was designed to study the difference effects between nicardipine and its two enantiomers on thoracic artery of rabbit. A high-performance liquid chromatographic method was used to prepare the two enantiomers of nicardipine. The thoracic artery of rabbit was removed. The vessels were cut into 3 mm in width and 15 mm in length spiral strips and immersed into tissue baths. The concentration-response curves of nicardipine and its enantiomers were obtained by cumulative administration of the vasoconstrictors. Nicardipine and the enantiomers could shift the dose-response curves of NE, KCI or CaCl$_2$ to right in a nonparallel manner and decrease the maximum effective in a concentration-depended manner, respectively. The pD$_2$' value of R-(-)-nicardipine showed significantly effective than that of nicardipine and S-(+)-nicardipine (P<0.01). There was not obviouse difference between the pD$_2$' value of nicardipine and S-(+)-nicardipine (P>0.05). The results demonstrate that the stereoselective interaction between R-(-)-nicardipine and L-calcium channel receptor is more stronger than that of S-(+)-nicardipine.

• 한국대기환경학회지
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• 제12권4호
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• pp.449-457
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• 1996

The main purpose of this study was to investigate sulfur dioxide removal performance of flue gas desulfurization system utilizing a Spray Absorption/Drying Reactor. In this system, the size of droplets was considered the most significant factor and tested using a PDA system. Lime slurry flow rate, operating temperature, calcium/sulfur (Ca/S) ratio and applied air pressure were selected as major operation variables and tested/analyzed in terms of system performance. The results are as follows. 1. The $SO_2$ removal efficiencies were 49%, 74%, 85% for Ca$(OH)_2$ slurry flow rate of 10, 20, 30 ml/min, which implies that the increase of slurry flow rate improves removal efficiency. The optimum slurry flow rate in this study was, however, considered 20 ml/min because of constraints of system troubles and absorbent utilization. 2. As Ca/S ratio increased, $SO_2$ removal efficiency was observed to increase. 3. As air pressure, at the atomizing nozzole, increased from 3 to 5 $kg/cm^2, SO_2$ removal efficiency increased from 74% to 80%, because of droplet size reduction due to pressure increase during atomizing process and the increase of surface area, helping mass transfer between gas and liquid phase.

• 식품산업과 영양
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• 제7권3호
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• pp.39-43
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• 2002

본 연구에서는 전통적으로 한방에서 성장 촉진을 위하여 사용된 녹각, 우슬, 구기자, 두충, 오미자 및 용안 등의 한약재 추출물과 액상칼슘을 각각 첨가하여 4구간의 빵을 제조하여 품질 특성을 비교 분석하였다. 빵의 물성을 측정한 결과, strength, hardness는 한약재 추출물과 액상칼슘의 첨가량이 많을수록 높아지는 경향을 나타냈었으며 cohesiveness, springiness, gumminess 및 brittleness는 감소하는 경향으로 나타났다. 빵의 내부와 표면의 색도(L,a,b)는 첨가량에 따라 차이가 있었으며 저장 4일째에 각각 변화 정도의 차이가 있었다. $37^{\circ}$ 에서 4일간 저장 후 일반세균은 무첨가구 $15\times10^3CFU/g$에 비하여 한약재 추출물 및 액상칼슘 첨가량이 많은 구간에서는 급격히 감소하여 보존성이 높게 나타났다. 관능적 특성은 실험구간에 따른 유의적 차이는 크게 나타나지 않았으며, 각각의 실험구간에 따른 칼슘함량을 비교 분석한 결과. 한약재 추출물과 액상칼슘이 많은 구간에서 높게 나타나는 경향이었다. 이상의 결과를 바탕으로 성장촉진 한약재 및 액상칼슘을 기능성 소재로서 제빵에 활용 가능할 것으로 생각된다.

• 한국재료학회지
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• 제20권1호
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• pp.1-6
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• 2010

Geopolymer materials are attractive as inorganic binders due to their superior mechanical and eco-friendly properties. In the current study, geopolymer-based cement was prepared using aluminosilicate minerals from fly-ash with KOH as an alkaline-activator and $Na_2SiO_3$ as liquid glass. Then, calcium carbonate powder from a clam shell was mixed with the geopolymer and the mixture was coated on a concrete surface to provide points of attachment for environmental organisms to grow on the geopolymers. We investigated the effect of the shell powder grain size on the microstructure and bonding property of the geopolymers. A homogeneous geopolymer layer coated well on the concrete surface via aluminosilicate bonding, but the adhesiveness of the shell powder on the geopolymer cement was dependent on the grain size of the shell powder. Superior adhesive characteristics were shown in the shell powder of large grain size due to the deep penetration into the geopolymer by their large weight. This kind of coating can be applied to the adhesiveness of eco-materials on the surface of seaside or riverside blocks.

• Journal of Pharmaceutical Investigation
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• 제29권3호
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• pp.171-177
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• 1999

Lidocaine(2-Diethylaminoaceto-2', 6'-xylidide) was transdennally delivered by iontophoresis and the effect of enhancer on the delivery of lidocaine was studied. We delivered lidocaine through the skin of hairless mouse using diffusion cell and investigated the effect of the amount of cation salts such as sodium chloride, calcium acetate, zinc acetate and aluminum acetate on the drug delivery. The amounts of transported drugs and adsorbed metal ions were measured by HPLC(High Perfonnance Liquid Chromatography) and AAS(Atomic Absorption Spectrophotometry), respectively. The addition of zinc acetate and aluminum acetate greatly enhanced the delivery of lidocaine. The detection of two metal ions by AAS seemed to support the idea that the astringency effect of these ions were the main reason for the enhancement of transdermal delivery.