• Title/Summary/Keyword: linkage structures

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Research on Preparation of Sheath-Core Bicomponent Composite Ion Exchange Fibers and Absorption Properties to Metal Ion

  • Ding, Zhi-Jia;Qi, Lu;Ye, Jian-Zhong
    • Macromolecular Research
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    • v.16 no.1
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    • pp.21-30
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    • 2008
  • Based on the sheath-core bicomponent composite fibers with modified polystyrene (PS) and the modified polypropylene (PP), composite fibers obtained were further cross-linked and sulphonated with chlorosulphonic acid to produce strong acidic cation ion exchange fibers. The structures of the fibers obtained were characterized using Fourier transform infrared (FT-IR) spectroscopy, differential scanning calorimetry (DSC) etc. The optimal technology of the fibers obtained is discussed. The static absorption capacity of the sheath-core bicomponent composite cation exchange fibers for $Zn^{2+}$, $Cu^{2+}$ was determined. The absorption kinetics and major factors affecting the absorption capacities of $Zn^{2+}$, $Cu^{2+}$ were studied, and its chemical stability and regenerating properties were probed. The results suggest that cation exchange fibers with better mechanical properties and higher exchange capability were obtained. Moreover, this type of ion exchange fiber has good absorption properties and working stability to various metal ions. Hence, they have higher practicability.

The Effect of Trade Integration on Business Cycle Synchronization in East Asia

  • NGUYEN, Vinh Thi Hong;HOANG, Thuy Thi Thanh;NGUYEN, Sang Minh
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.8
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    • pp.225-231
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    • 2020
  • The paper aims to investigate the impact of trade integration on business cycle synchronization for the East Asian countries during 2005- 2017 based on the endogeneity hypothesis of Optimum Currency Area criteria. We test the determinants of business cycles by calculating bilateral trade, financial integration, and business cycle synchronization. Applying the system Generalized Method of Moments for dynamic panel data models, the results show that business cycle synchronization is highly associated with trade and financial integration. These findings confirm the endogeneity hypothesis that more trade integration will mitigate asymmetric shocks, and have a positive impact on the business cycle synchronization. The increased trade intensity and financial linkage lead to more correlated business cycles in East Asia. Apart from trade and financial integration, the trade structure differential, monetary policy similarity also influence the business cycle comovement. The significantly negative impact of trade structure differential on business cycle synchronization suggests that countries with less similar structures are more likely to undergo asymmetric shocks. The results also indicate that monetary policy matters for output comovement. This study recommends that the East Asian countries should focus on bilateral trade as well as financial integration with each other to reap benefits from the integration process.

A SMA-based actuation system for a fish robot

  • Le, Chan Hoang;Nguyen, Quang Sang;Park, Hoon Cheol
    • Smart Structures and Systems
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    • v.10 no.6
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    • pp.501-515
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    • 2012
  • We design and test a shape memory alloy (SMA)-based actuation system that can be used to propel a fish robot. The actuator in the system is composed of a 0.1 mm diameter SMA wire, a 0.5 mm-thick glass/epoxy composite strip, and a fixture frame. The SMA wire is installed in a pre-bent composite strip that provides initial tension to the SMA wire. The actuator can produce a blocking force of about 200 gram force (gf) and displacement of 3.5 mm at the center of the glass/epoxy strip for an 8 V application. The bending motion of the actuator is converted into the tail-beat motion of a fish robot through a linkage system. The fish robot is evaluated by measuring the tail-beat angle, swimming speed, and thrust produced by the tail-beat motion. The tail-beat angle is about $20^{\circ}$, the maximum swimming speed is about 1.6 cm/s, and the measured average thrust is about 0.4 gf when the fish robot is operated at 0.9 Hz.

EphB/ephrinB Signaling in Cell Adhesion and Migration

  • Park, Inji;Lee, Hyun-Shik
    • Molecules and Cells
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    • v.38 no.1
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    • pp.14-19
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    • 2015
  • Eph receptors and their ligands, ephrins, represent the largest group of the receptor tyrosine kinase (RTK) family, and they mediate numerous developmental processes in a variety of organisms. Ephrins are membrane-bound proteins that are mainly divided into two classes: A class ephrins, which are linked to the membrane by a glycosylphosphatidylinositol (GPI) linkage, and B class ephrins, which are transmembrane ligands. Based on their domain structures and affinities for ligand binding, the Eph receptors are also divided into two groups. Trans-dimerization of Eph receptors with their membrane-tethered ligands regulates cell-cell interactions and initiates bidirectional signaling pathways. These pathways are intimately involved in regulating cytoskeleton dynamics, cell migration, and alterations in cellular dynamics and shapes. The EphBs and ephrinBs are specifically localized and modified to promote higher-order clustering and initiate of bidirectional signaling. In this review, we present an in-depth overview of the structure, mechanisms, cell signaling, and functions of EphB/ephrinB in cell adhesion and migration.

Semantic Network Analysis about Comments on Internet Articles about Nurse Workplace Bullying (간호사 괴롭힘 관련 인터넷 포털 기사에 대한 댓글의 의미연결망 분석)

  • Kim, Chang Hee;Moon, Seong Mi
    • Journal of Korean Clinical Nursing Research
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    • v.25 no.3
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    • pp.209-220
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    • 2019
  • Purpose: A significant amount of public opinion about nurse bullying is expressed on the internet. The purpose of this study was to analyze the linkage structures among words extracted from comments on internet articles related to nurse workplace bullying using semantic network analysis. Methods: From February 2018 to April 2019, comments made on news articles posted to the Daum and Naver web portal containing keywords such as "nurse", "Taeum", and "bullying" were collected using a web crawler written in Python. A morphological analysis performed with Open Korean Text in KoNLPy generated 54 major nodes. The frequencies, eigenvector centralities, and betweenness centralities of the 54 nodes were calculated and semantic networks were visualized using the UCINET and NetDraw programs. Convergence of iterated correlations (CONCOR) analysis was performed to identify structural equivalence. Results: This paper presents results about March 2018 and January 2019 because these months had highest number of articles. Of the 54 major nodes, "nurse", "hospital", "patient", and "physician" were the most frequent and had the highest eigenvector and betweenness centralities. The CONCOR analysis identified work environment, nurse, gender, and military clusters. Conclusion: This study structurally explored public opinion about nurse bullying through semantic network analysis. It is suggested that various studies on nursing phenomena will be conducted using social network analysis.

Assignment of ¹H and $^{13}C$ Nuclear Magnetic Resonances of Ganglioside $G_{A1}$

  • 이경익;전길자;류경임;방은정;최병석;김양미
    • Bulletin of the Korean Chemical Society
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    • v.16 no.9
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    • pp.864-869
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    • 1995
  • Investigation of the structures of the gangliosides has proven to be very important in the understanding of their biological roles such as regulation of differentiation and growth of cells. We used nuclear magnetic resonance spectros-copy in order to investigate the structure of GA1. In order to do this, the assignment of spectra is a prerequisite. Since GA1 does not have polar sialic acid, the spectral overlap is severe. In order to solve this problem, we use 2D NMR spectroscopy and heteronuclear 1H/13C correlated spectroscopy in this study. Here, we report the complete assignment of the proton and the carbon spectra of the GA1 in DMSO-d6-D20 (98:2, v/v). These assignments will be useful for interpreting 1H and 13C NMR data from uncharacterized oligosaccharides and for determining the linkage position, the number of sugar rings, and the sequence of new ganglioside. Amide proton in ring Ⅲ shows many interring nOes and has intramolecular hydrogen bonding. This appears to be an important factor in tertiary folding of GA1. Based on this assignment, determination of three dimensional structure of GA1 will be carried out. Studies on the conformational properties of GA1 may lead to a better understanding of the molecular basis of its functions.

A Study on IFC extended and GIS linkage using BIM as Facility Management - Case Study on Bridge and Tunnel of Infra BIM - (BIM을 유지관리로 활용하는 IFC 확장 및 GIS 연계 연구 - 기반시설 BIM의 교량, 터널 중심으로 -)

  • Chae, Jae-Hyun;Choi, Hyun-Sang;Lee, Ji-Yeong
    • Journal of KIBIM
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    • v.12 no.3
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    • pp.1-17
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    • 2022
  • As the technology of Smart City and Digital Twin is developing, techniques to integrate BIM data of infrastructure facilities into GIS are becoming more critical. Hence, this study aims to manage BIM data representing bridge and tunnel structures through the Industry Foundation Classes (IFC) standard and to develop a method to link these IFC-compliant files to the GIS standard CityGML without loss of information. We analyze the criteria for creating BIM data for bridges and tunnels by reviewing the BIM guidelines set by each client. We use these criteria to suggest methods for data management based on InfraBIM as a specific IFC class standard. Furthermore, we perform model analysis to determine the necessary design and construction field-appropriate model process and Level of Detail (LOD). From the model analysis, we conclude that the classified BIM models can be used as base data to generate BIM models of bridges and tunnels for facility management.

Fully coupled multi-hull/mooring/riser/hawser time domain simulation of TLP-TAD system with MR damper

  • Muhammad Zaid Zainuddin;Moo-Hyun Kim;Chungkuk Jin;Shankar Bhat
    • Ocean Systems Engineering
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    • v.13 no.4
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    • pp.401-421
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    • 2023
  • Reducing hawser line tensions and dynamic responses to a certain level is of paramount importance as the hawser lines provide important structural linkage between 2 body TLP-TAD system. The objective of this paper is to demonstrate how MR Damper can be utilized to achieve this. Hydrodynamic coefficients and wave forces for two bodies including second-order effects are obtained by 3D diffraction/radiation panel program by potential theory. Then, multi-hull-riser-mooring-hawser fully-coupled time-domain dynamic simulation program is applied to solve the complex two-body system's dynamics with the Magneto-Rheological (MR) Damper modeled on one end of hawser. Since the damping level of MR Damper can be changed by inputting different electric currents, various simulations are conducted for various electric currents. The results show the reductions in maximum hawser tensions with MR Damper even for passive control cases. The results also show that the hawser tensions and MR Damper strokes are affected not only by input electric currents but also by initial mooring design. Further optimization of hawser design with MR Damper can be done by active MR-Damper control with changing electric currents, which is the subject of the next study.

The Information Modeling Method based on Extended IFC for Alignment-based Objects of Railway Track (선형중심 객체 관리를 위한 확장된 IFC 기반 철도 궤도부 정보모델링 방안)

  • Kwon, Tae Ho;Park, Sang I.;Seo, Kyung-Wan;Lee, Sang-Ho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.31 no.6
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    • pp.339-346
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    • 2018
  • An Industry Foundation Classes(IFC), which is a data schema developed focusing on architecture, is being expanded to civil engineering structures. However, it is difficult to create an information model based on extended IFC since the BIM software cannot provide support functions. To manage a railway track based on the extended IFC, this paper proposed a method to create an alignment-centered separated railway track model and convert it to an extended IFC-based information model. First, railway track elements have been classified into continuous and discontinuous structures. The continuous structures were created by an alignment-based software, and discontinuous structures were created as independent objects through linkage of the discretized alignment. Second, a classification system and extended IFC schema for railway track have been proposed. Finally, the semantic information was identified by using the property of classification code and user interface. The availability of the methods was verified by developing an extended IFC-based information model of the Osong railway site.

Ribosomal Crystallography: Peptide Bond Formation, Chaperone Assistance and Antibiotics Activity

  • Yonath, Ada
    • Molecules and Cells
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    • v.20 no.1
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    • pp.1-16
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    • 2005
  • The peptidyl transferase center (PTC) is located in a protein free environment, thus confirming that the ribosome is a ribozyme. This arched void has dimensions suitable for accommodating the 3'ends of the A-and the P-site tRNAs, and is situated within a universal sizable symmetry-related region that connects all ribosomal functional centers involved in amino-acid polymerization. The linkage between the elaborate PTC architecture and the A-site tRNA position revealed that the A-to P-site passage of the tRNA 3'end is performed by a rotatory motion, which leads to stereochemistry suitable for peptide bond formation and for substrate mediated catalysis, thus suggesting that the PTC evolved by genefusion. Adjacent to the PTC is the entrance of the protein exit tunnel, shown to play active roles in sequence-specific gating of nascent chains and in responding to cellular signals. This tunnel also provides a site that may be exploited for local co-translational folding and seems to assist in nascent chain trafficking into the hydrophobic space formed by the first bacterial chaperone, the trigger factor. Many antibiotics target ribosomes. Although the ribosome is highly conserved, subtle sequence and/or conformational variations enable drug selectivity, thus facilitating clinical usage. Comparisons of high-resolution structures of complexes of antibiotics bound to ribosomes from eubacteria resembling pathogens, to an archaeon that shares properties with eukaryotes and to its mutant that allows antibiotics binding, demonstrated the unambiguous difference between mere binding and therapeutical effectiveness. The observed variability in antibiotics inhibitory modes, accompanied by the elucidation of the structural basis to antibiotics mechanism justifies expectations for structural based improved properties of existing compounds as well as for the development of novel drugs.