• Bulletin of the Korean Chemical Society
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• v.32 no.10
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• pp.3566-3570
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• 2011

A series of 2,4,6-tripyridyl pyridines were synthesized, and evaluated for their antitumor cytotoxicity, topoisomerase I and II inhibitory activity. From the eighteen prepared compounds, compounds 10-12 have shown better or similar cytotoxicity against several human cancer cell lines as compared to 2,2':6',2"-terpyridine and doxorubicin. Especially, compound 10 exhibited the most potent cytotoxicity better than positive controls. Structure-activity relationship study indicated that 2,2':6',2"-terpyridine skeleton has an important role in displaying significant cytotoxicity against several human cancer cell lines.

• Proceedings of the International Microelectronics And Packaging Society Conference
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• 2002.05a
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• pp.69-73
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• 2002

In ceramic systems, many components including embedded passives and TRL(transmission line) are used for composition of 3-dimensional circuit. So the exact analysis on this components, As for the TRL's, material properties including electrical conductivity of metal, loss factor and effective dielectric constant of dielectric material and geometrical factors like roughness of surface, vias, dimension of stripline structure have a large effect on the charactersistics of transmission lines. In this research, of effect of material and geometrical factors on the characteristics of stripline structure is analyzed and quantified by simulation and measurement.

• Korean Institute of Interior Design Journal
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• v.25 no.4
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• pp.35-42
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• 2016

The purpose of this study is the analyze the spatial structure and housing component of the prairie style house of Frank Lloyd Wright during the Prairie Era which is between 1893-1910. The research results can be summarized as follows 1) In spite of European style influences which were fashionable at the time, Wright tried to attempt altering the space and form of his works (houses) from his unique architectural style. 2) All solid walls which are usually inside the square prairie and the cross floor plans were removed for interaction between the outside and inside spaces in a house creating an organic space. So the inside space of the house feels wider than the original space because of the available natural light. 3) Frank Lloyd Wright's early works were similar to the homes built at that time. However, as time passed, he remembered and was influenced by the Frobel's educational system blocks he played with as a child as well as the surrounding Midwestern USA prairies where he grew up. 4) The early prairie floor plan was square divided into nine equal parts which is classic floor planning. Wright, however, created his new unique architectural style. His style has developed into the prairie style and various floor plans. 5) Wright introduced a 3-dimensional architectural form of composition (cantilever, long eaves, etc.) to express symmetry and horizontal lines of the house. 6) Rather than emphasizing vertical lines in his works, Wright began emphasizing more horizontal lines like the horizontal lines of the actual prairies. This meant the surrounding environment of a house is always in nature.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.26 no.5
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• pp.463-470
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• 2015

In this paper, a new dual-band bandpass filter(BPF) that has resonators and feed lines with Stepped-Impedance Resonator(SIR) structures is proposed. Feed lines with SIR structure provide maximum magnetic field points which occur at the same locations of the input and output feed lines, so the insertion loss of BPF was reduced. Applying the SIR structure to the BPF for the first passband improves rejection characteristics between the first passband and the second passband. It reduces the coupling between the BPF for the first passband and the BPF for the second passband, so it makes the dual-band BPF more compact. The proposed design method provides independent changes of both the center frequency and the bandwidth for each resonator, and also improves filtering characteristics. The validity of the proposed design method is confirmed by comparisons between the designed parameters and the measured results satisfying WLAN specifications.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.3
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• pp.459-466
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• 2022

Switching surges are a common type of phenomenon that occur on any sort of power system network. These are more pronounced on long transmission lines and in high voltage converter stations. At AC/DC hybrid transmission lines, the insulation coordination of such lines is mainly dictated by the peak level of switching surges, the most dangerous of which include three phase line energization and AC/DC converter station. The power system structure consist of AC/DC hybrid transmission lines which is combination of AC 765kV and ±500kV HVDC 1 bipole system for contingency analysis. The power system under study and its components are simulated using EMTDC software package, the effects of the various AC/DC mixing power lines are reviewed. The developed models of EMTDC conversion lines based on combination of AC/DC system are simulated and the characteristics of switching surge over-voltage from its results are discussed.

• Journal of Astronomy and Space Sciences
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• v.32 no.1
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• pp.73-80
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• 2015

The Yang-gyeong-gyu-il-ui (兩景揆日儀) is a kind of elevation sundial using three wooden plates. Sang-hyeok Lee (李尙爀, 1810~?) and Byeong-cheol Nam (南秉哲, 1817~1863) gave descriptions of this sundial and explained how to use it in their Gyu-il-go (揆日考) and Ui-gi-jip-seol (儀器輯說), respectively. According to Gyu-il-go (揆日考) there are two horizontal plates and two vertical plates that have lines of season and time. Subseasonal (節候) lines are engraved between seasonal (節氣) lines, subdividing the interval into three equal lines of Cho-hu (初候, early subseason), Jung-hu (中候, mid subseason) and Mal-hu (末候, late subseason); there are 13 seasonal lines for a year, thus resulting in 37 subseasonal lines; also, there are 12 double-hour (時辰) lines for a day engraved on these plates. The only remaining artifact of Yang-gyeong-gyu-il-ui was made in 1849 (the $15^{th}$ year of Heon-jong) and is kept at the Korea University Museum. We have compared and analyzed Yang-gyeong-gyu-il-ui and similar western sundials. Also, we have reviewed the scientific aspect of this artifact and built a replica. Yang-gyeong-gyu-il-ui is a new model enhanced from the miniaturization development in the early Joseon Dynasty and can be applied to the southern part of the tropic line through a structure change.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.39 no.1
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• pp.63-72
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• 1994

The relationships among the endosperm structure, physicochemical characteristics and cooking and milling properties were examined in this study by using the isogenic lines which have the same genetic background except starch characteristics. The isogenic lines were bread by combining three pairs of genes, of waxy or non-waxy, fractured or round starch granule, and shrunken or plump endosperm. Although grains weight and chemical compositions of the endosperms did not differ widely, but cooking qualities, amylose contents, $\beta$-glucan viscosities were significant differences between isogenic types. Water absorptions and expansibilities were highest in waxy lines, and lowest in fratured starch granular lines; the smaller the seed sizes were, the higher the water absorptions were. Mixogram pattern of cooked barley varied with the starch properties and milling properties were excellent in fractured granular lines, whereas those properties of the waxy and shrunken endosperm lines were not good.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.6
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• pp.517-523
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• 2013

Naphthyridine compounds are important, because they exhibit various biological activities including anticancer, antimicrobial, and anti-inflammatory activity. Some naphthyridines have antimitotic effects or demonstrate anticancer activity by inhibiting topoisomerase II. These compounds have been investigated as potential anticancer agents, and several compounds are now part of clinical trials. A series of naphthyridine derivatives were evaluated for their in vitro cytotoxic activities against human cervical cancer (HeLa), leukemia (HL-60), and prostate cancer (PC-3) cell lines using an MTT assay. Some compounds (14, 15, and 16) were more potent than colchicine against all three human cancer cell lines and compound (16) demonstrated potency with $IC_{50}$ values of 0.7, 0.1, and $5.1{\mu}M$, respectively. Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were used for quantitative structure-activity relationship (QSAR) molecular modeling of these compounds. We obtained accurate and predictive three-dimensional QSAR (3D-QSAR) models as indicated by the high PLS parameters of the HeLa ($q^2$, 0.857; $r^2$, 0.984; $r^2\;_{pred}$, 0.966), HL-60 ($q^2$, 0.777; $q^2$, 0.937; $r^2\;_{pred}$, 0.913), and PC-3 ($q^2$, 0.702; $q^2$, 0.983; $r^2\;_{pred}$, 0.974) cell lines. The 3D-QSAR contour maps suggested that the C-1 NH and C-4 carbonyl group of the naphthyridine ring and the C-2 naphthyl ring were important for cytotoxicity in all three human cancer cell lines.

• Journal of Electrical Engineering and Technology
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• v.6 no.6
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• pp.760-768
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• 2011

The performance of transmission lines and its shielding design during a lightning phenomenon are quite essential in the maintenance of a reliable power supply to consumers. The leader progression model, as an advanced approach, has been recently developed to calculate the shielding failure rate (SFR) of transmission lines using geometrical data and physical behavior of upward and downward lightning leaders. However, such method is quite time consuming. In the present paper, an effective method that utilizes artificial neural networks (ANNs) to create a metamodel for calculating the SFR of a transmission line based on shielding angle and height is introduced. The results of investigations on a real case study reveal that, through proper selection of an ANN structure and good training, the ANN prediction is very close to the result of the detailed simulation, whereas the Processing time is by far lower than that of the detailed model.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.15 no.6
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• pp.529-534
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• 2002

Recently, As the higher frequency in clock of digital system being demanded and the density of circuits gets high for purpose of making light and minimizing system, the study for solution of digital signal distortion being interested. In this paper, the distortion of square pulse caused by dispersion as it propagates along a single microstrip line and crosstalk between lines on the Multi-Transmission Lines (MTL) is investigated. The dispersion and crosstalk of pulse signals is analyzed regarding to the structure of transmission line such as relative permittivity, substrate height, strip width of the microstrip line and pulse width of signal pulse.