• 대한토목학회논문집
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• 제32권2A호
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• pp.65-73
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• 2012

본 연구에서는 PSC 거더교의 장경간 적용을 위해 개발된 Half-Decked PSC 거더의 구조적 성능을 실험하였다. 이를 위해 힌지-롤러의 지점 조건의 단순교로 설계된 60 m 경간의 실물 크기 거더를 제작하여 4점 재하실험을 수행하였다. 거더의 중앙을 기준으로 양쪽으로 5.5 m 씩 떨어진 위치에 가력장치를 설치 후 1 kN/sec의 속도로 하중을 재하하여 총 4단계에 걸쳐 반복하중을 가하였다. 1단계부터 4단계까지 1,000 kN, 1,200 kN, 1,500 kN, 2,000 kN의 하중을 재하하고 제거하기를 반복하며 거더의 변위, 콘크리트와 철근의 변형률, 균열 등을 확인하였다. 이를 분석하여 거더의 내하력을 평가하고 하중 제거 시 나타나는 복원력 등을 살펴보았다. 1,400 kN 인근에서 초기 휨균열이 발생하여, 이 시점부터 하중 재하 시 비선형 성이 나타나며 뚜렷한 잔류변형이 계측되었다. 초기 균열이 1등교 기준의 사용하중보다 2배 이상 큰 하중에서 계측되어 충분한 내하력을 갖고 있는 것으로 나타났다. 실험 결과의 검증을 위해 수치해석을 수행하여 결과 값을 비교하였고 그 결과 실험 결과와 해석 결과의 유사한 거동을 확인하였다. 본 연구에서 개발된 거더의 정적재하실험을 통하여 그 구조적 성능을 입증하였으며, 이를 바탕으로 Half-Decked PSC 거더 형식의 60 m 경간 실교량 설계 적용 가능성을 확인하였다.

• 약학회지
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• 제55권5호
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• pp.411-418
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• 2011

The dissolution test method and an analytical procedure by HPLC were developed and validated for nafronyl oxalate capsules and tramadol hydrochloride capsules. These drugs were not yet characterized by the dissolution specifications in the Korean Pharmaceutical Codex. So, with each reference and test drugs, we did the preliminary and standard experiments based on the Korean Pharmacopeia Guideline of dissolution testing for solid oral dosage forms. The dissolution test for nafronyl oxalate capsules was carried out under sink conditions as follows: dissolution medium phosphate buffer pH 6.8, paddle rotation speed 100 rpm and vessel volume 900 ml. More than 80% of its label amount was released within 30 min in this method. Also the dissolution test for tramadol hydrochloride capsules was carried out under sink conditions as follows: dissolution medium water, paddle rotation speed 50 rpm and vessel volume 900 ml. More than 90% of its label amount was released within 15 min in this method. The dissolution samples were analyzed with a validated HPLC analytical procedure. The analytical methodology showed acceptable values in terms of specificity, linearity, precision and accuracy. The dissolution test methods described above were adequate for the purpose and may be proposed as a pharmacopeial standard to assess the performance of nafronyl oxalate capsules and tramadol hydrochloride capsules. Furthermore, the outcomes of this study were expected to help create an environment where safe and high quality drugs would be distributed on the domestic market making contributions to advancing public health.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권2호
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• pp.654-670
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• 2020

Workers at construction sites are easily exposed to many dangers and accidents involving falls, tripping, and missteps on stairs. However, researches on construction site monitoring system to prevent work-related injuries are still insufficient. The purpose of this study was to develop a wearable textile pressure insole sensor and examine its effectiveness in managing the real-time safety of construction workers. The sensor was designed based on the principles of parallel capacitance measurement using conductive textile and the monitoring system was developed by C# language. Three separate experiments were carried out for performance evaluation of the proposed sensor: (1) varying the distance between two capacitance plates to examine changes in capacitance charges, (2) repeatedly applying 1 N of pressure for 5,000 times to evaluate consistency, and (3) gradually increasing force by 1 N (from 1 N to 46 N) to test the linearity of the sensor value. Five subjects participated in our pilot test, which examined whether ascending and descending the stairs can be distinguished by our sensor and by weka assessment tool using k-NN algorithm. The 10-fold cross-validation method was used for analysis and the results of accuracy in identifying stair ascending and descending were 87.2% and 90.9%, respectively. By applying our sensor, the type of activity, weight-shifting patterns for balance control, and plantar pressure distribution for postural changes of the construction workers can be detected. The results of this study can be the basis for future sensor-based monitoring device development studies and fall prediction researches for construction workers.

• 한국항공우주학회지
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• 제46권10호
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• pp.823-832
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• 2018

일반적으로 항공기 운동 모델의 충실도는 대상 항공기의 비행시험 결과와 비교하여 검증한다. 따라서 성능 비교를 위한 기준 비행 데이터를 추출하는데, 각종 잡음이 포함된 방대한 양의 비행데이터를 처리하는 것은 많은 인력과 시간이 소요된다. 특히 회전익항공기는 축간 커플링 효과와 후류 간섭 효과 등으로 비선형성이 큰 특성을 가지고 있으며, 제자리 비행, 후진 비행 등의 다양한 기동을 수행하므로 비행 데이터를 처리하는 것이 복잡하다. 본 연구에서는 회전익항공기의 비행 데이터 처리 기준을 정의하고, 데이터마이닝 기법을 이용한 정적 및 동적 비행 데이터 자동 처리를 위한 절차와 방법을 제시한다. 최종적으로 비행데이터를 사용하여 제시한 방법을 검증한다.

• 비파괴검사학회지
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• 제27권5호
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• pp.442-448
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• 2007

원전 취약부위의 하나인 증기발생기 전열관의 확관/천이영역을 초음파로 검사하기 위한 장치를 개발하고 모의결함 시험편 및 자연결함 시험편을 이용하여 그 성능검증을 수행하였다. 10% 이상의 깊이를 가지는 모의결함은 모두 검출 가능했으며 20% 이상의 깊이를 가지는 모의결함은 그 크기도 재현성 있게 측정할 수 있었다. 순차적인 깊이를 가지는 모의결함을 이용한 실험결과 표준편차 3.27로 비교적 재현성 있는 결과를 얻었다. 자연결함을 포함하고 있는 시편을 이용한 실험결과, 결함의 진행 형태가 검출능에 영향을 미침을 알 수 있었고 결함의 깊이방향 형태가 비교적 잘 반영되므로 결함 단면 면적을 측정할 수 있는 가능성을 타진할 수 있었다.

• 한국대기환경학회지
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• 제18권1호
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• pp.39-49
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• 2002

In this study, limits of detection (LOD), accuracy and precision of four sampling/ analytical methods were evaluated and compared for the determination of airborne hexavalent chromium, Cr (VI). The methods include : (1) a combination of the National Institute for Occupational Safety and Health (NIOSH) Method 7600/U. S. Environmental Protection Agency (EPA) Method 218.6 (NIOSH/EPA Method) proposed by Shin and Paik, 2) two impinger methods using 2% NaOH/3% Na$_2$CO$_3$. (3) same as (2) but with 0.02 N NaHCO$_3$absorbing solution, and (4) the Occupational Safety and Health (OSHA) Method ID-215. An ion chromatograph/visible absorbance detector was used for the analysis of Cr (VI) in sample solution. Limit of detection (LOD) , analytical accuracy, and precision were also tested using Cr (VI) spike samples. Recoveries (as index of accuracy) and coefficient of variation (CV) (as a index of precision) were determined. Two-way ANOVA and Turkey's test were performed to test the significance in differences among recoveries and CVs of the methods. In all the methods, the peaks of Cr (VI) were separated sharply on chromatograms and exhibited a strong linearity with Cr (VI) concentrations in solution. The correlation coefficients of calibration curves typically ranged from 0.9997 to 0.9999, and the analytical LODs from 0.025 to 0.1$\mu\textrm{g}$/sample. All the method had good sensitivities and linearities between Cr (VI) levels and peak areas. The accuracies (% mean recoveries) of the methods ranged from 80.1 to 104.2%, while the precisions (pooled coefficient of variation) ranged from 3.16 to 4.43%. The impinger methods showed higher recoveries ( > 95%) than those of the PVC filter methods (the OSHA Method and the NIOSH/EPA Method). It was assumed that Cr (VI) on PVC filter was exposed to air and reduced to trivalent chromium, Cr (III), whereas it was stabilized in alkali solution contained in impinger. Thus, a special treatment of Cr (VI) samples collected on PVC filters may be required.

• 분석과학
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• 제11권4호
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• pp.243-247
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• 1998

백금을 함유한 항암제로 신장과 신경계에 심각한 부작용을 일으키는 cisplatin의 혈중 농도를 flameless atomic absorption spectrometry법(FAAS)으로 분석하였다. 이 방법은 시료전처리 과정이 필요 없어 신속하고 간단한 분석법이다. 검정곡선에 대한 직선성을 조사한 결과 20~1000ng/mL 농도 범위에서 r=0.999로 나타났으며, 정확도는 50 ng/mL 이상의 농도에서 상대표준편차가 5.0% 이하 이었다. 그리고, 혈장시료 $200{\mu}L$에 대한 검출한계는 10 ng/mL 이었다. 본 방법은 cisplatin의 최적 치료 조건과 독성 경감을 위한 혈중 모니터링에 그 활용이 크게 기대된다.

• 대한의용생체공학회:의공학회지
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• 제37권5호
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• pp.168-177
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• 2016

In this paper we present an implantable pressure sensor to measure real-time blood pressure by monitoring mechanical movement of artery. Sensor is composed of inductors (L) and capacitors (C) which are formed by microfabrication and direct bonding on two biocompatible substrates (quartz). When electrical potential is applied to the sensor, the inductors and capacitors generates a LC resonance circuit and produce characteristic resonant frequencies. Real-time variation of the resonant frequency is monitored by an external measurement system using inductive coupling. Structural and electrical simulation was performed by Computer Aided Engineering (CAE) programs, ANSYS and HFSS, to optimize geometry of sensor. Ultrafast laser (femto-second) cutting and MEMS process were executed as sensor fabrication methods with consideration of brittleness of the substrate and small radial artery size. After whole fabrication processes, we got sensors of $3mm{\times}15mm{\times}0.5mm$. Resonant frequency of the sensor was around 90 MHz at atmosphere (760 mmHg), and the sensor has good linearity without any hysteresis. Longterm (5 years) stability of the sensor was verified by thermal acceleration testing with Arrhenius model. Moreover, in-vitro cytotoxicity test was done to show biocompatiblity of the sensor and validation of real-time blood pressure measurement was verified with animal test by implant of the sensor. By integration with development of external interrogation system, the proposed sensor system will be a promising method to measure real-time blood pressure.

• 한국지반환경공학회 논문집
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• 제16권4호
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• pp.33-40
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• 2015

현재 제안되고 있는 압밀과 관련된 상관식들은 분석대상 지역이 국외나 국내의 특정지역에 국한되거나 자료의 숫자를 늘리기 위해 여러 지역의 실험자료를 통합함으로써 적용에 무리가 따르는 경우가 많다. 또한 취득된 자료의 명확한 통계적 평가없이 모형이 개발되어 왔다. 따라서 본 연구에서는 시험자료의 불확실성을 최대한 줄이기 위해 서해안의 연약지대를 한강과 금강, 영산강으로 대분하고 물리적 특성치와 역학적 특성치에 대하여 정규성 검증과 회귀분석을 수행하였다. 분석결과 압축지수와 수정압축지수의 직선성이 강하며, 모든 지역에서 수정압축지수와 초기간극비가 가장 상관성이 양호하고 다음으로 전체단위중량, 함수비, 액성한계 순으로 나타났다. 또한 깊이에 따른 과압밀비는 모든 지역에서 깊이가 5~6m 이하의 경우 과압밀비의 폭이 크게 나타나며, 5m~6m 이상일 경우 일정한 값을 가지는 패턴을 보였다.

• 한국의상디자인학회지
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• 제10권3호
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• pp.173-180
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• 2008

Cotton, wool, cotton/wool blended (80:20) and tencel fabrics were treated with low temperature oxygen plasma, enzymes (cellulase or protease), or oxygen plasma-enzyme and they were examined for dyeing and handling properties for environment friendly finishing. The appropriate conditions for cellulase treatment were enzyme concentration of 3g/l, pH of 5, and $60^{\circ}C$ for one hour, and for protease treatment were enzyme concentration of 4g/l, pH of 8, and $60^{\circ}C$ for one hour. The equilibrium uptake of a direct dye on cotton changed with plasma treatment and plasma-cellulase treatment, and the rate of dyeing slightly decreased. When wool was dyed with acid dye, the equilibrium dye uptake did not change with plasma, protease treatment nor plasma-protease treatment, however, the rate of dyeing had increased with plasma-protease treatment. From these results, it is assumed that plasma attacks the surface of the fiber, and enzyme mainly affects the inner part of the fiber. Plasma treatment did not affect mechanical properties related to the handling of fabrics. The handling test showed increased extension at maxmum load(EM), tensile energy(WT) with decreased tensile resilience (RT), and the fabrics became softer but resilience decreased slightly with enzyme treatment. The bending recidity(B), hysteresis of bending moment(2HB), and hysteresis of shear force at five degrees(2HG5) decreased, however, shear stiffness(G) increased. I knew the plasma pre-treatment made fabrics softer with lower koshi(stiffness). The handling of plasma pre-treated fabrics was better than that of enzyme-treated fabrics. When we pre-treated fabrics, the handling test showed decreased coefficient of friction(MIU), geometrical roughness(SMD), while the surface of fabrics became smoother and numeri increased. Even though compression resilience(RC) increased, fukurami(bulky property) and compressive elasticity, decreased due to the linearity of compression-thickness curve(LC) and compression energy(WC).