• Title/Summary/Keyword: linear energy transfer

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Characterization of Imaging and Physical Properties in Digital Radiography System (디지탈 X-선 촬영시스템의 영상 및 물리적 특성 분석)

  • Kim, Jong-Hyo;Lee, Tae-Soo;Park, Kwang-Suk;Han, Man-Cheong;Lee, Choong-Woong;Min, Byoung-Goo
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.26 no.7
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    • pp.112-124
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    • 1989
  • In order to evaluate imaging performance of newly developed digital radiography system which requires scanning time as short as 0.7 sec and patient exposure as low as 3 mR, we have investigated its imaging and physical properties such as sensitivity characteristic, scatter fraction, detective quantum efficiency, modulation transfer function, and contrast detail diagram. The results show that the digital radiography system has linear sensitivity to the incident energy, and superior contrast resolving power with less X-ray exposure than conventional film-screen system. These performances are resulted from excellent scatter rejection capability and high detective quantum efficiency of digital radiography system.

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Comparison of Parameter Using the Repair Survival Model Irradiated High-LET (LET 증가에 따른 회복 생존 모델의 파라미터 값 비교)

  • Choi, Eunae
    • Journal of the Korean Society of Radiology
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    • v.11 no.4
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    • pp.177-181
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    • 2017
  • Dose response curves using absorbed dose to the biological effect are usually available in case of conventional X beam. However, absorbed dose is not consider in treatment planning for carbon beam such as heavy ions. Because the biological effects also depend on other quantities such as the local variation, which is often characterized by the linear energy transfer (LET). So LQ model cannot explain the entire response of fractionated carbon beam irradiation. The variation in LET with penetration depth leads to substantial differences in biological effect of carbon beam. And it is therefore essential in treatment planning to calculate not only the absorbed dose but also the LET to estimate the biological outcome of the radiation of interest. LET variation plays an important role in the fractionated irradiations. It is suggested that consideration of LET is necessary in biophysical model.

A Study on the Visualization of Ice-formation Phenomena of Bath Water to Decide Maintenance Period of Gas Heater (가스히터 보수주기 결정을 위한 히터내부 열전달 매체액 결빙현상 가시화에 관한 연구)

  • Lee J. H.;Ha J. M.;Sung W. M.
    • Journal of the Korean Institute of Gas
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    • v.5 no.3 s.15
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    • pp.1-8
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    • 2001
  • This study was carried out for the purpose of determination of maintenance period and investigation of weak point due to freeze when the gas heater of KOGAS valve station Is not operated in winter season. 3-dimensional non-linear numerical simulation was conducted in order to predict the time and location which bath water in heater reaches to ice point. FLUENT V 5.0, commercial code, is used for thermal fluid flow analysis. We thought this was problem of heat conduction solving the energy equation and modeled gas heater by using the real geometry and scale for performing the 3-dimensional simulation. It was analyzed complex heat transfer phenomena considering convection due to air on surface, conduction in insulation material, natural convection of liquid in heater and heat loss through the pipe.

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Radioprotective effects of delphinidin on normal human lung cells against proton beam exposure

  • Kim, Hyun Mi;Kim, Suk Hee;Kang, Bo Sun
    • Nutrition Research and Practice
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    • v.12 no.1
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    • pp.41-46
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    • 2018
  • BACKGROUND/OBJECTIVES: Exposure of the normal lung tissue around the cancerous tumor during radiotherapy causes serious side effects such as pneumonitis and pulmonary fibrosis. Radioprotectors used during cancer radiotherapy could protect the patient from side effects induced by radiation injury of the normal tissue. Delphinidin has strong antioxidant properties, and it works as the driving force of a radioprotective effect by scavenging radiation-induced reactive oxygen species (ROS). However, no studies have been conducted on the radioprotective effect of delphinidin against high linear energy transfer radiation. Therefore, this study was undertaken to evaluate the radioprotective effects of delphinidin on human lung cells against a proton beam. MATERIALS/METHODS: Normal human lung cells (HEL 299 cells) were used for in vitro experiments. The 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay assessed the cytotoxicity of delphinidin and cell viability. The expression of radiation induced cellular ROS was measured by the 2'-7'-dicholordihydrofluorescein diacetate assay. Superoxide dismutase activity assay and catalase activity assay were used for evaluating the activity of corresponding enzymes. In addition, radioprotective effects on DNA damage-induced cellular apoptosis were evaluated by Western blot assay. RESULTS: Experimental analysis, including cell survival assay, MTT assay, and Western blot assay, revealed the radioprotective effects of delphinidin. These include restoring the activities of antioxidant enzymes of damaged cells, increase in the levels of pro-survival protein, and decrease of pro-apoptosis proteins. The results from different experiments were compatible with each to provide a substantial conclusion. CONCLUSION: Low concentration ($2.5{\mu}M/mL$) of delphinidin administration prior to radiation exposure was radioprotective against a low dose of proton beam exposure. Hence, delphinidin is a promising shielding agent against radiation, protecting the normal tissues around a cancerous tumor, which are unintentionally exposed to low doses of radiation during proton therapy.

수십 MeV 양성자빔을 이용한 금속나노입자 제조 기술 및 장치

  • Kim, Gye-Ryeong;Jeong, Myeong-Hwan;Na, Se-Jin
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.493-494
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    • 2011
  • 수 MeV~수십 MeV 양성자빔을 이용해 백금, 은 등의 나노입자 제조실험을 수행하였다. 나노 입자는 의료분야와 산업 분야에서 그 응용성이 다양해 여러 지 방법을 이용한 제조기술이 개발되고 있다. 전자빔, 감마선, 양성자빔 등의 방사선을 이용한 나노입자 제조방법은 가장 널리 이용되고 있는 화학적 제조방법에 비해 비교적 공정이 단순하다는 장점을 가지고 있지만 공정 변수의 제어방법이 확립되어 있지 않아 이에 대한 연구가 필요한 실정이다. 특히, 양성자빔의 경우 에너지에 따른 투과깊이의 조절과 플럭스나 총 선량, LET (Linear Energy Transfer) 등의 변수와 제조된 나노입자의 상관관계 등에 대한 연구가 선행되어야 한다. 본 논문에서는 백금산 용액을 이용한 나노입자 제조 결과와 대면적 양성자빔을 이용하기 위한 초음파 이용 나노입자제조장치의 제작 및 실험결과에 대해 논하고 향후 건설될 100MeV 선형 양성자가속장치의 나노입자 제조실험에의 응용을 위한 이용시설을 소개하고자 한다. 나노입자 제조실험은 한국원자력의학원의 MC-50 싸이클로트론을 이용하여 수행하였으며, 가속기로부터 인출되는 에너지는 35, 45MeV, 빔전류는 수십 nA~수${\mu}A$의 범위 내에서 조절하였다. 제조된 나노입자는 TEM을 이용하여 그 크기와 분포를 관찰하였다. 대면적의 양성자빔을 이용하는 경우, 수mm의 두께와 수십 cm의 직경을 가지는 원반 모양의 시료용기를 사용하여 양성자빔의 에너지와 선량을 정확히 조절할 수 있게 되는데 이 때 용기 내 시료와 양성자빔간의 균일한 반응을 위해 용액을 적절하게 섞어 주어야만 한다. 이러한 목적으로 초음파를 이용하여 나노입자 제조장치를 제작하여 실험을 수행하였다. 나노입자 제조는 현재 교과부의 지원으로 경주 건천지역에 건설되고 있는 100MeV 선형양성자가속기의 주요 이용 분야 중의 하나로 20MeV 빔라인 중 한 개의 빔라인과 표적실을 나노입자 제조 등의 실험을 위한 시설로 구축 중이다. 최대 평균전류 1.6mA 까지 가능하고 펄스폭은 0.05~1.33 msec까지 조절가능하도록 개발되고 있다.

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Routing Protocol for Wireless Sensor Network Considering Data Transmission Stability and Load Quantity (선형적 데이터 전달의 안정성과 부하량을 고려한 무선 센서 네트워크 라우팅 프로토콜)

  • Hwang, Min;Cheon, Seung-Hwan;You, Jin-Ho;Kien, Nguyen Trung;Lee, Guee-Sang
    • The Journal of the Korea Contents Association
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    • v.7 no.11
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    • pp.111-119
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    • 2007
  • Sensor networks are needed for special purposes such as collecting or transmitting information by using sensor devices, for which various routing protocols have been proposed. Among existing protocols, the modified PEGASIS routing technique is known to be effective when applied to cases with directional transmissions of data. However it does not consider recovery from errors or guaranteeing stability in data transmission, while sensor devices performing repetitive relays and controls are prone to errors. In this paper, a double relay routing protocol for Zigbee based sensor networks where data are transfered reliably with a linear direction. The proposed protocol is effective in the sense that it secures the relaible transmission of data with minimal energy consumption based on a directional data transfer. A streetlight control system has been presented as an application of the proposed protocol.

Listener Auditory Perception Enhancement using Virtual Sound Source Design for 3D Auditory System

  • Kang, Cheol Yong;Mariappan, Vinayagam;Cho, Juphil;Lee, Seon Hee
    • International journal of advanced smart convergence
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    • v.5 no.4
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    • pp.15-20
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    • 2016
  • When a virtual sound source for 3D auditory system is reproduced by a linear loudspeaker array, listeners can perceive not only the direction of the source, but also its distance. Control over perceived distance has often been implemented via the adjustment of various acoustic parameters, such as loudness, spectrum change, and the direct-to-reverberant energy ratio; however, there is a neglected yet powerful cue to the distance of a nearby virtual sound source that can be manipulated for sources that are positioned away from the listener's median plane. This paper address the problem of generating binaural signals for moving sources in closed or in open environments. The proposed perceptual enhancement algorithm composed of three main parts is developed: propagation, reverberation and the effect of the head, torso and pinna. For propagation the effect of attenuation due to distance and molecular air-absorption is considered. Related to the interaction of sounds with the environment, especially in closed environments is reverberation. The effects of the head, torso and pinna on signals that arrive at the listener are also objectives of the consideration. The set of HRTF that have been used to simulate the virtual sound source environment for 3D auditory system. Special attention has been given to the modelling and interpolation of HRTFs for the generation of new transfer functions and definition of trajectories, definition of closed environment, etc. also be considered for their inclusion in the program to achieve realistic binaural renderings. The evaluation is implemented in MATLAB.

System Design of SIGMA(KHUSAT-3) CubeSat Mission

  • Lee, Seongwhan;Lee, Junkyu;Kum, Kanghoon;Lee, Hyojeong;Seo, Junwon;Shin, Youra;Jeong, Seonyoung;Shin, Jehyuck;Cheon, Junghoon;Kim, Hanjun;Jin, Ho;Nam, Uk-Won;Kim, Sunghwan;Lee, Regina;Lessard, Marc R.
    • The Bulletin of The Korean Astronomical Society
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    • v.39 no.1
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    • pp.54.1-54.1
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    • 2014
  • Kyung Hee University has been developing a CubeSat for the space science mission called SIGMA (Scientific cubesat with Instrument for Global Magnetic field and rAdiation), which includes TEPC (Tissue Equivalent Proportional Counter) and a magnetometer. SIGMA has a 3-unit CubeSat, and the weight is about 3.2 kg. The main payload is TEPC which can measure the Linear Energy Transfer (LET) spectrum and calculate the equivalent dose for the complicated radiation field in the space. The magnetometer is a secondary payload using a miniaturized fluxgate magnetometer. We expect it to have a 1 nT resolution in the dynamic range of ${\pm}65535$ nT. An Attitude Control System (ACS) spins the SIGMA spacecraft 4 rpm with the spin axis perpendicular to the ecliptic plane. Full duplex communication is consists of VHF uplink and S-band and UHF downlink. In this paper, we introduce the system design and the scientific purpose of the SIGMA CubeSat mission.

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An analytic solution for the stirling engines with saw-toothed piston motions in adiabatic cylinders (단열실린더내에서 톱날파형 피스톤운동을 하는 스터링기관에 대한 해석적인 해)

  • 유호선
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.12 no.5
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    • pp.1197-1205
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    • 1988
  • An analytical method to predict qualitative performance characteristics of the Stirling Engines in the preliminary design stages is investigated. Both the expansion and the compression cylinder are treated as adiabatic and piston motions are approximated as saw-toothed waves. Basic equations which were originally proposed by Finkelstein consist of mass conservation and energy balances for each adiabatic cylinder. The approximation on piston motions and physical conditions make it possible to divide an engine cycle into four fundamental processes. In each process, first, pressure can be expressed as a function of the crank angle by solving a nonlinear first order ordinary differential equation and other thermodynamic variables are determined in turn. Application of the cyclic steady condition to the whole processes can complete a cycle. Also, further analysis results in analytic expressions for cyclic work and heat transfer in terms of the engine parameters and thermodynamic variables at boundary points. The results are expected useful as a quick reference for the engine performances. Finally, the present method can be applied to the other adiabatic analyses on the Stirling Engines with piece wise linear piston motions, if mass variations are predictable.

Electrochemical Sensor for Non-Enzymatic Glucose Detection Based on Flexible CNT Fiber Electrode Dispersed with CuO Nanoparticles (산화구리 나노입자가 분산된 CNT fiber 유연 전극 기반의 글루코스 검출용 비효소적 전기화학센서)

  • Min-Jung Song
    • Korean Chemical Engineering Research
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    • v.61 no.1
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    • pp.52-57
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    • 2023
  • This study is a basic research for the development of high performance flexible electrode material. To enhance its electrochemical property, CuO nanoparticles (CuO NPs) were introduced and dispersed on surface of CNT fiber through electrochemical deposition method. The CNT fiber/CuO NPs electrode was fabricated and applied to electrochemical non-enzymatic glucose sensor. Surface morphology and elemental composition of the CNT fiber/CuO NPs electrode was characterized by scanning electron microscope (SEM) with energy dispersive X-ray spectrometry (EDS). And its electrochemical characteristics were investigated by cyclic voltammetry, electrochemical impedance spectroscopy and chronoamperometry. The CNT fiber/CuO NPs electrode exhibited the good sensing performance for glucose detection such as high sensitivity, wide linear range, low detection limit and good selectivity due to synergetic effect of CNT fiber and CuO NPs. Based on the unique property of CNT fiber, CuO NPs were provide large surface area, enhanced electrocatalytic activity, efficient electron transport property. Therefore, it is expected to develop high performance flexible electrode materials using various nanomaterials.