• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.9
• /
• pp.3691-3696
• /
• 2015

Background: Cancer loci comprise heterogeneous cell populations with diverse cellular secretions. Therefore, disseminating cancer-specific or cancer-associated protein antigens from tissue lysates could only be marginally correct, if otherwise not validated against precise standards. Materials and Methods: In this study, 2DE proteomic profiles were examined from lysates of 13 lung-adenocarcinoma tissue samples and matched against the A549 cell line proteome. A549 matched-cancer-specific hits were analyzed and characterized by MALDI-TOF/MS. Results: Comparative analysis identified a total of 13 protein spots with differential expression. These proteins were found to be involved in critical cellular functions regulating pyrimidine metabolism, pentose phosphate pathway and integrin signaling. Gene ontology based analysis classified majority of protein hits responsible for metabolic processes. Among these, only a single non-predictive protein spot was found to be a cancer cell specific hit, identified as Armadillo repeat-containing protein 8 (ARMC8). Pathway reconstruction studies showed that ARMC8 lies at the centre of cancer metabolic pathways. Conclusions: The findings in this report are suggestive of a regulatory role of ARMC8 in control of proliferation and differentiation in lung adenocarcinomas.

• Clinics in Shoulder and Elbow
• /
• v.21 no.3
• /
• pp.113-119
• /
• 2018

Background: This study was undertaken to evaluate the positional relationship between planes of the glenoid component (the scapular plane and the perpendicular plane to the glenoid) and its surrounding structures. Methods: Computed tomography (CT) images of both shoulders of 100 patients were evaluated using the 3-dimensional CT reconstruction program ($Aquarius^{(R)}$; TeraRecon). We determined the most lateral scapular bony structure of the scapular plane and measured the shortest distance between the anterolateral corner of the acromion and the scapular plane. The distance between the scapular plane and the midpoint of the line connecting the posterolateral corner of acromion and the anterior tip of the coracoid process (fulcrum axis) was also evaluated. The perpendicular plane was then adjusted to the glenoid and the same values were re-assessed. Results: The acromion was the most lateral scapular structure of scapular plane and perpendicular plane to the glenoid. The average distance from the anterolateral corner of the acromion to the scapular plane was $10.44{\pm}5.11mm$, and to the plane perpendicular to the glenoid was $9.55{\pm}5.13mm$. The midpoint of fulcrum axis was positioned towards the acromion and was measured at $3.90{\pm}3.21mm$ from the scapular plane and at $3.84{\pm}3.17mm$ from the perpendicular plane to the glenoid. Conclusions: Our data indicates that the relationship between the perpendicular plane to the glenoid plane and its surrounding structures is reliable and can be used as guidelines during glenoid component insertion (level of evidence: Level IV, case series, treatment study).

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.45 no.2
• /
• pp.29-36
• /
• 2008

In this paper we propose a real-time method to estimate a pointing region from two camera images. In general, a pointing target exists in the face direction when a human points to something. Therefore, we regard the direction of pointing as the straight line that connects the face position with the fingertip position. First, the method extracts two points in the face and the fingertips region by using detecting the skin color of human being. And we used the 3D geometric information to obtain a pointing detection and its region. In order to evaluate the performance, we have build up an ICIGS(Interactive Cinema Information Guiding System) with two camera and a beam project.

• Korean Journal of Digital Imaging in Medicine
• /
• v.12 no.2
• /
• pp.127-132
• /
• 2010

In this study, the correlation among the changes of Modulation Transfer Function(MTF) in the noise and high-contrast resolution and the change of Contrast to noise ratio(CNR) in the low-contrast resolution will be examined to investigate the estimation of image quality according to the type of algorithms. The image data obtained by scanning American Association of Physicists in Medicine(AAPM) phantom was applied to each algorithm and the exposure condition of 120 kVp, 250 mAs, and then the CT number and noise were measured. The MTF curved line of the high-contrast resolution was calculated with Point Spread Function(PSF) by using the analysis program by Philips, resulting in 0.5 MTF, 0.1 MTF and 0.02 MTF respectively. The low-contrast resolution was calculated with CNR and the uniformity was measured to each algorithm. Since the measurement value for the uniformity of the equipment was below ${\pm}$ 5 HU, which is the criterion figure, it was found to belong to the normal range. As the algorithm got closer from soft to edge, the standard deviation of CT number increased, which indicates that the noise increased as well. As for MTF, 0.5 MTF, 0.1 MTF and 0.02 MTF were all sharp algorithms, and as the algorithm got closer from soft to edge, it was possible to distinguish more clearly with the naked eye. On the other hand, CNR gradually decreased, because the difference between the contrast hole CT number and the acrylic CT number was the same while the noise of hole increased.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.31 no.11
• /
• pp.1598-1610
• /
• 2007

The knit design of this study was developed from reconstruction of Gustav Klimt images including gorgeous colors, symbolic lines, patterns and decorations, and the purpose was laid at making of unique, creative costume image with modem sense and adding artistic value on crochet knit wears. As for the contents and method of this study, We analysed formative aspects of Gustav such as line, color and shape Klimt in his art, and reviewed the cases where his works had been employed in modern costume. The conclusions are as follows; First, painting is important motif for contemporary costume design, and according to the individual thinking and expression, can be a major momentum for development of original design. Especially the organic lines and decorative patterns of Gustav Klimt paintings were suitable for rich decorative motif of costume design. Second, the unique colors of Gustav Klimt paintings can, if introduced to costume, allow new color combination. Third, crochet technic, by the texture of material, can present rich expression even with the basic knitting only. The embroidery metallic thread which is the main material for this study, was good for expression of gorgeous and classy image, in spite of the difficulties from its typical luster and embossed feeling. And the mohair, used as decorative motif, allowed more three dimensional expression with its rich voluminous and tangling property. Fourth, in applying Gustav Klimt paintings to costume design, other technics such as knitting, beading, applique, and patchwork helped creation of more unique clothes, presenting possibilities of rich artistic expression.

• Archives of Reconstructive Microsurgery
• /
• v.25 no.2
• /
• pp.25-28
• /
• 2016

Purpose: Reconstruction of small defects of the dorsal fingers and toes is a challenging task. Although adipofascial flap is widely used for these areas, additional refinements are warranted. In this paper, we define the appropriate defect size in the finger and toes that can be treated with the adipofascial flap, refine its surgical indications and present a few surgical tips. Materials and Methods: Twelve patients with dorsal defects of the fingers and toes were treated with a random-type adipofascial turn-over flap and skin graft. If the defect area exceeded the size that could be covered by a conventional design, the flap base was designed in oblique or curvilinear fashion to lengthen the flap. For accurate defect coverage, the width of the flap base was designed in an asymmetrical shape depending on the defect configuration, varying the width from 0.3 to 1.0 cm, as opposed to the standard 0.5 to 1.0 cm width. Moreover, the lateral limit of the flap was defined as the lateral axial line. The size of the defect ranged from $3.0{\times}1.7cm$ to $1.5{\times}1.3cm$. Results: All flaps survived completely. Gliding function of the hand was well preserved and there was no evidence of tendon adhesion. Conclusion: The small defect in the dorsal finger and toe can be defined as less than one phalanx-length, measuring about $3.0{\times}2.0cm$ in size. If the defect exceeds this dimension, it is recommended that a different option be considered. We believe the adipofascial flap is an excellent option for treating small defects.

• Korean Journal of Geomatics
• /
• v.5 no.1
• /
• pp.7-19
• /
• 2005

Photogrammetric mapping procedures have gone through major developments due to significant improvements in its underlying technologies. The availability of GPS/INS systems greatly assist in direct geo-referencing of the acquired imagery. Still, photogrammetric datasets taken without the aid of positioning and navigation systems need control information for the purpose of surface reconstruction. Point features were, and still are, the primary source of control for the photogrammetric triangulation although other higher-order features are available and can be used. LIDAR systems supply dense geometric surface information in the form of three dimensional coordinates with respect to certain reference system. Considering the accuracy improvement of LIDAR systems in the recent years, LIDAR data is considered a viable supply of photogrammetric control. To exploit LIDAR data, new challenges are poised concerning the representation and reference system by which both the photogrammetric and LIDAR datasets are described. In this paper, registration methodologies will be devised for the purpose of integrating the LIDAR data into the photogrammetric triangulation. Such registration methodologies have to deal with three issues: registration primitives, transformation parameters, and similarity measures. Two methodologies will be introduced that utilize straight-line and areal features derived from both datasets as the registration primitives. The first methodology directly incorporates the LIDAR lines as control information in the photogrammetric triangulation, while in the second methodology, LIDAR patches are used to produce and align the photogrammetric model. Also, camera self-calibration experiments were conducted on simulated and real data to test the feasibility of using LIDAR patches for this purpose.

• The Journal of Advanced Prosthodontics
• /
• v.4 no.3
• /
• pp.153-157
• /
• 2012

PURPOSE. The study was conducted to compare the radiographic and clinical methods of measuring the horizontal condylar guidance (HCG) values. MATERIALS AND METHODS. The condylar guidance was measured using the radiographic (CT scan) and three clinical methods i.e. the wax protrusive records, Lucia jig record and intraoral central bearing device in 12 patients aged between 20-40 years irrespective of sex. The records were taken and transferred on the semi-adjustable articulator to record the HCG values. The CT scan was taken for 3D reconstruction of the mid facial region. Frankfort horizontal plane (FHP) and a line extending from the superior anterior most point on the glenoid fossa to the most convex point on the apex of articular eminence (AE) was marked on the CT scan. An angle between these two lines was measured on both right and left sides to obtain condylar inclination angle. Three interocclusal protrusive wax and jig records were taken and transferred to the semi adjustable articulator. Three readings were recorded on each side. Similarly the records were taken and transferred to the same articulator using the intra oral central bearing device to record the readings. RESULTS. The statistical analysis showed insignificant differences in the HCG values between the right and left sides [(P=.589 (CT), P=.928 (wax), P=.625 (jig), P=.886 (tracer)]. The clinical methods provided low Pearsons correlation values [(R = 0.423 (wax), R = 0.354 (jig), R = 0.265 (tracer)] for the right as well as the left sides when compared with the CT values. Among the clinical methods, jig and wax method showed strong level of association which is statistically significant while the intra-oral tracer showed weak association with the other two methods. CONCLUSION. The right and left HCG values were almost similar. The CT scan showed higher HCG values than the clinical methods and among the clinical methods, values obtained from all the methods were comparable.

• Korean Journal of Cleft Lip And Palate
• /
• v.8 no.2
• /
• pp.87-94
• /
• 2005

Patients with unilateral cleft lip and palate (UCLP) generally demonstrate the asymmetries in the lip, nose and the naso-maxillary complex. And their skeletal asymmetries are known to be derived from the displacement of nasal septum, anterior nasal spine (ANS) and the pre-maxilla toward the non-affected side during the developmental and growth period. Due to the interruption of the important facial muscles, which are critical for the symmetric growth of premaxilla, functional matrix system fails to develop and results in the displacement of the ANS toward the non-affected side and nasal asymmetry. Therefore the rhinoplasty for CLP patients is required to have inter-skeletal and muscular rearrangement in the naso-maxillary complex in order to let them recover from esthetic and physiologic imbalances. And functional cheilorhinoplasty (FCR) has been a representative treatment of choice for this concept of treatment modality. The outcome and prognosis of primary or repair FCR have been known to be definitely affected by timing of the operation as well as adequate reconstruction of naso-labial muscles. However, sometimes FCR has an ineffective treatment results for patients after the facial growth period, and the limited rhinoplasty around the nose often fails to bring satisfying results. In order to circumvent this limitation, we performed ANS osteotomy for patients with unilateral CLP showing asymmetric nose, as an alternative way for corrective rhinoplasty. We could observe that the nose was rearranged along the facial mid-line by this osteotomy design and asymmetries were evidently improved postoperatively. Here we present this osteotomy method in CLP patients.

• Korean Journal of Optics and Photonics
• /
• v.18 no.1
• /
• pp.8-13
• /
• 2007

In this paper, we analyze the optical properties of the transmission grating recorded in a reflection-type photopolymer. Recording and reconstruction of the micropattern using a total internal reflection hologram applied to a reflection type photopolymer are studied. The transmission-type photopolymer was shown to have the maximum diffraction efficiency in $40^{\circ}C$ symmetric structure. However, that of reflection type photopolymer was more than 90% at $60{\sim}80^{\circ}$. The line and point patterns with the interval of $1{\mu}m$ are recorded successfully and can be observed when the micro objective lenses with 10 and 100 time magnification are used.