• Natural Product Sciences
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• v.18 no.3
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• pp.166-170
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• 2012

The purification of the MeOH extract from the aerial parts of Erythronium japonicum using column chromatography furnished a new megastigmane glucoside, erthrojaponiside (1), together with six known megastigmane derivatives (2 - 7). The structure of the new compound (1) was determined through 1D and 2D NMR spectral data analysis and chemical means. The isolated compounds (1 - 7) were tested for cytotoxicity against four human tumor cells in vitro using a Sulforhodamin B (SRB) bioassay.

• Natural Product Sciences
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• v.4 no.4
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• pp.230-233
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• 1998

The methanol extract of Asparagus racemosus root was evaluated for its anti-inflammatory activity on carrageenin and serotonin-induced rat hind paw oedema models. The extract (200 and 400 mg/kg) showed maximum inhibition of oedema of 18.6% and 33.7% at 3 h with carrageenin and 22.2% and 40.5% at 5 h with serotonin-induced rat paw oedema respectively. The experimental models tested, where the effect produced by the extract was compared to that of phenylbutazone, a prototype non-steroidal anti-inflammatory drug.

• Korean Journal of Pharmacognosy
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• v.24 no.3
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• pp.251-254
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• 1993

The anthocyanin isolated from the petals of Erythronium japonicum was elucidated as delphinidin 3-rutinoside on the basis of PPC and UV spectral evidences. To evaluate phytochemical and botanical utilization of this plant, the quantitative analysis of anthocyanin content was carried out by using the visible absorption spectra at 540nm. By the results of our experiment, it was found that the anthocyanin content of petals collected from the summit of Mt. Odae are higher than that of the lowest region. However, there is no significant difference between the anthocyanin contents of the petals collected from the east- and west-side area of the mountain.

• Journal of the Korean Society of Food Science and Nutrition
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• v.27 no.5
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• pp.968-972
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• 1998

Allium tuberosum Rotter(Liliaceae) is a perennial herb of which leaves are used for food. Leek has been reported to have pharmacological effects including alleviations of abdominal pain, diarrhea, hematemesis, snakebite, and asthma. To investigate the effect of dietary leek supplementation on the drug-metaboizing enzymes, quinone reductase(QR) and arylhydrocarbon hydroxylase(AHH) activities in the liver, stomach, small intestine and lung, and on the plasma testosterone and dihydrosterone hormone levels, mice were fed 2% and 5% leek diets for 8 weeks. Quinone reductase, an anticarcinogenic enzyme, was significantly induced in stomach, small intestine, and lung but slightly lowered in hepatic tissue in the experimental groups compared to control group. Arylhydrocarbon hydroxylase activity, involved in bioactivation of procarcinogens, was significantly decreased in liver and lung. Leek feeding led to the reduction in the plasma level of dihydrotestosterone which is associated with the incidence of prostate cancer. These findings support the potential chemopreventive activity of leek supplementation.

• Journal of Forest and Environmental Science
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• v.39 no.3
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• pp.150-154
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• 2023

Heloniopsis orientalis (Liliaceae) is an important horticultural crop native to Korea. Under natural conditions, germination is poor and plant growth is delayed. Therefore, we have developed a vegetative propagation method to produce plants with vigorous growth characteristics via tissue culture. The regenerated shoots were then initiated directly from leaf explants on an MS medium containing either 0.5 to 2.0 mg/L 2,4-D or 1.0 to 3.0 mg/L BA. Healthy plantlets with adventitious roots were formed on the medium supplemented with 1.0 mg/L BA (81%). BA triggered callus initiation without caulogenesis or rhizogenesis, and callus formation was better on the half-strength MS medium than on the full-strength medium. This in vitro propagation protocol will be useful for conservation, as well as for mass propagation.

• Current Research on Agriculture and Life Sciences
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• v.8
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• pp.71-82
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• 1990

In order to collect the plant genetic resources in Korea, the medicinal plants were surveyed from 1987 to 1989 in Kyungbuk province and at the several areas in Kyuognam and Choongbuk province. The medicinal plants of 456 species in 118 families were investigated in these regions. Among them, 249 species were belonged to 19 families, Compositae, Liliaceae, Leguminosae, Poiygonaceae, Labiatae, Rosaceae, Umbelliferae, Gramineae, Solanaceae, Cucurbitaceae, Ranunculaceae, Cruciferae, Rutaceae, Araliaceae, Araceae, Moraceae, Scrophulariaceae, Caryopyhllaceae, and Convolvulaceae, and others were belonged to 99 families. They have been used mostly for urination, gastroenteric disoder, robustness, antiphlogistic, anodyne, cough medicine, fever remedy, hemostatic, and 9 species of them have been used for anticancer medicine. The medicinal plant resources which were planted in the fields, gardens, parks, roadsides, and glass house, were 93 species for ornamental, 50 for medicine, 27 for vegetable, 14 for food, 5 for vegetable fruit, 13 for fruit, 5 for oil, 6 for tea, 9 for shade, and 14 for other purposes. Most of investigated plants were perennial, and flowered from June to August. The root parts were most frequently used as medicine, and other parts were used in the order of leaf and stem, whole plants, flower, seed, and fruit. Among the 456 species, 191 species in 87 families were investigated to be important medicinal plants.

• Natural Product Sciences
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• v.11 no.2
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• pp.67-74
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• 2005

The ethanolic extracts of the leaves and bulbs of Allium victorialis var. platyphyllum (Liliaceae) collected from Daegwallyoung (D) and Ullung Island (U) in Korea were obtained using three different extracting methods. The first extracts, DL-1 DB-1, UL-1 and UB-1, were obtained from leaves (L) and bulbs (B) dried at $90^{\circ}C$, respectively, and the second extracts, DL-2, DB-2, UL-2 and UB-2, were obtained by extracting the leaves and bulbs of fresh plant parts. The third extracts DL-3, DB-3, UL-3 and UB-3 were obtained by incubating leaves and bulbs at $36^{\circ}C$. The six extracts obtained from A. victorialis var. platyphyllum at Daegwanllyoung (cultivated site) were orally administered to examine for a possible antihepatotoxic effect in $CCl_4-induced$ rats. DL-1 exhibited the most pronounced effect. The extracts inhibited serum ALT, AST, SDH, ${\gamma}-GT$, ALP and LDH activities elevated by $CCl_4$ injection and attenuated decreased glutathione S-transferase, glutatione reductase and ${\gamma}-glutamylcysteine$ synthetase activities and a decreased hepatic glutathione. However, the extracts obtained from Ullung Is. (native site) were less active than the extracts from Daegwallyoung, suggesting that A. victorialis var. platyphyllum from the cultivated site is more useful for functional food than of native site. These results also suggest that the antihepatotoxic effect is due to a higher content of hepatic glutathione. Gas chromatography of the twelve extracts showed significantly different sulfides, disulfides or trisulfides contents belonging to volatile sulfur substances (VSS). Nine components were identified on the basis of their mass spectra, namely, dimethyl disulfide, dimethyl trisulfide, diallyl disulfide, dipropyl disulfide, allyl methyl sulfide, allyl methyl trisulfide, 2-vinyl-4H-1,3-dithiin, 3,4-dihydro-3-vinyl-1,2-dithiin, and allithiamine. Extract DL-1 had the highest VSS content. Dried plant materials contained larger amounts of the VSSs than other extracts, and the leaves contained larger amount than the bulbs. These results suggest that heat treatment increases the antiheaptotoxic ability of A. victorialis var. platyphyllum by increasing the proportion of VSSs.

• Korean Journal of Pharmacognosy
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• v.36 no.2 s.141
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• pp.109-115
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• 2005

The herb of Allium victorialis var. platyphyllum (Liliaceae) has been used as an edible wild herb and to treat heart failure and gastritis. We have already reported antihyperlipidemic anti-tumor effects of this plant. To enlarge the commercial availability of this food, it was investigated whether the extracts of A. victorialis var. platyphyllum reduce hyperlipidemia and obesity or not. The plants tested in this experiment were collected from two eco-types of Is. Ullung and Mt. Odae cultivated at Pyongchang. Extracts were prepared by extracting the fresh leaves and those dried at $36^{\circ}C$ and $90^{\circ}C$, respectively. Pretreatment with the ethanolic extracts for two weeks(p.o.) reduced serum triglyceride-, total cholesterol- and LDL-cholesterol contents in rats induced by Triton WR-1339, respectively. Furthermore, oral administration of the extracts also inhibited the hyperlipidemia induced with oral diet of 30% corn oil. In the other attempt to find to alleviate the obesity, the model rats with obesity were induced by the high fat-diet for six weeks. Post-treatment with the extracts for two weeks significantly reduced the hyperlipidemia. Retroperitoneal-, epidymal- and total abdominal fat pad weights were considerably reduced at 100 mg/kg oral administration of the extracts. Increased feces lipid contents were also found in the rat treated with the extracts. The extract may lead to the higher activity in treatment of hyperlipidemia and obesity than of the dried one.

• Journal of Life Science
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• v.17 no.3 s.83
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• pp.328-333
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• 2007

Genetic diversity and population structure of eleven Liriope platyphylla (Liliaceae) populations in Korea were determined using genetic variation at 20 allozyme loci. The percent of polymorphic loci within the enzymes was 55.9%. Genetic diversity at the species level and at the population level was high(Hes = 0.178; Hep = 0.168, respectively), whereas the extent of the population divergence was relatively low ($G_{ST}$ = 0.064). $F_{IS}$, a measure of the deviation from random mating within the 11 populations, was 0.311. Total genetic diversity values ($H_T$) varied between 0.0 and 0.535, giving an average over all polymorphic loci of 0.323. The interlocus variation in within population genetic diversity ($H_S$) was high (0.305). An indirect estimate of the number of migrants per generation (Nm = 3.66) indicates that gene flow is high among Korean populations of the species. In addition, analysis of fixation indices revealed a substantial heterozygosity deficiency in some populations and at some loci. Mean genetic identity between populations was 0.988. It is highly probable that directional toward genetic uniformity in a relatively the homogenous habitat is thought to be operated among Korean populations of L. platyphylla.

• Korean Journal of Environment and Ecology
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• v.10 no.2
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• pp.211-239
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• 1997

The flora of Oesorak in the Soraksan National Park including Chombongsan(Mountain) and Kwanmobong(Peak) were surveyed from February to August, 1996. These areas have very rich and diverse flora;620 taxa with 89 families, 321 genera, 526 species, 2 subspecies, 89 varieties and 3 forms in the Oesorak, 404 taxa with 251 genera, 350 species, 1 subspecies, 51 varieties and 2 forms in the Chombongsan(Mountain), 286 taxa with 206 genera, 233 species, 1 subspecies, 50 varieties and 2 forms in Kwanmobong(peak). The Oesorak had very distinct floristic characteristics such as the wild habitats of Asarum maculatum(Aristolochiaceae) and Ilex macropoda(Aquifoliaceae). In the phyorgeographical point of view, the six species such as Sapium japonicum (Euphorbiaceae), Euphorbia joldini(Euphorbiaceae), Ilex macropoda (Aquifoliaceae), Styrax japonica (Styracaceae), Carex sideros ticta (Cyperaceae) and Asarum maculatum (Aristolochiaceae) were naturalized into this region, while the 17 taxa such as Abies neprolepis(Pinaceae), Pinus pumila(Pinaceae), Thuja koraiensis(Cupressaceae), Allium senescens(Liliaceae), Lilium distichum(Liliaceae), Saxifraga punctata(Saxfragaceae), Rosa marretii(Rosaceae), Bupleurum euphorbioides(Umbelliferae), Androsace cortusaefolia (Primulaceae), Peducularis mandshurica(Scrophulariaceae) and Leontopodium coreanum (Compositae) were distrivuted to this region. The colonizing weedy species such as Ixris repens (Compositae) were distributed to this region. The colonizing weedy species losa(Labiatae) and Rosa rugosa(Rosaceae) were naturalized into ca. 900m at sea level mainly due to the sand soil from the seashore. Mountain roadbed is susceptible than other areas to the slippery road problems, due largely to snow and rain, particularly during winter. Sand soils from seashore are utilized to minimize this slip in traffic operation.