Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Evaluation of Anti-inflammatory Activity of Asparagus racemosus Willd. (Liliaceae) root extract

  • Mandal, Subhash C. (Division of Pharmacognosy, Dept. of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Maiti, B.C. (Indian Institute of Chemical Biology) ;
  • Maity, Tapan K. (Division of Pharmacognosy, Dept. of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Pal, M. (Division of Pharmacognosy, Dept. of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Saha, B.P. (Division of Pharmacognosy, Dept. of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University)
  • Published : 1998.12.01
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Abstract

The methanol extract of Asparagus racemosus root was evaluated for its anti-inflammatory activity on carrageenin and serotonin-induced rat hind paw oedema models. The extract (200 and 400 mg/kg) showed maximum inhibition of oedema of 18.6% and 33.7% at 3 h with carrageenin and 22.2% and 40.5% at 5 h with serotonin-induced rat paw oedema respectively. The experimental models tested, where the effect produced by the extract was compared to that of phenylbutazone, a prototype non-steroidal anti-inflammatory drug.

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