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The Inhibitory Effects of Houttuynia cordata $T_{HUNB}$ against Cadmium induced Cytotoxicity (II) (어성초의 카드뮴에 대한 독성억제효과 (II))

  • 이정호;유일수;이기남;정우영;한두석;백승화
    • YAKHAK HOEJI
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    • v.44 no.5
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    • pp.432-439
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    • 2000
  • This study was condo더ed to investigate the antitoxic component in aqueous extract of Houttuynia cordata $T_{HUNB}$. The results were as follows: Generally, detoxification effects by Houttuynia cordata $T_{HUNB}$ extract increased in proportion to the extract concentrations in rats. When 40 mBtg dosage of Houttuynia cordata $T_{HUNB}$ extract was administrated, Houttynia cordata $T_{HUNB}$ extract showed the highest antitoxic effects in metallothionein induction. After the extract treatment, body weights increased in proportion to the extract concentrations. However, after 3 weeks, the body weight decreased insignificantly. From the above results, Houttuynia cordate $T_{HUNB}$ extract increased metallothionein concentration and decreased the toxicity of cadmium in rats. In vitro the antitoxic activity of aqueous extract of Houttuynia cordata $T_{HUNB}$ on NIH 373 fibroblasts was evaluated by the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetra-zoliumbromide) and SRB (sulforhodamine B protein) assays. The light microscopic study was carried out to observe morphological changes of the treated cells. These results were obtained as follows; The concentration of 10$^{-2}$ mg/ml of Houttuynia cordata $T_{HUNB}$ extract was shown significant antitoxic activity The number of NIH 373 fibroblasts were increased and tend to regenerate. These results suggest that Houttuynia cordata THUNB extract retains a potential antitoxic activity.oxic activity.

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Mechanical behavior test and analysis of HEH sandwich external wall panel

  • Wu, Xiangguo;Zhang, Xuesen;Tao, Xiaokun;Yang, Ming;Yu, Qun;Qiu, Faqiang
    • Advances in concrete construction
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    • v.13 no.2
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    • pp.153-162
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    • 2022
  • Prefabricated exterior wall panel is the main non-load-bearing component of assembly building, which affects the comprehensive performance of thermal insulation and durability of the building. It is of great significance to develop new prefabricated exterior wall panel with durable and lightweight characteristics for the development of energy-saving and assembly building. In the prefabricated sandwich insulation hanging wall panel, the selection of material for the outer layer and the arrangement of the connector of the inner and outer wall layers affect the mechanical performance and durability of the wall panels. In this paper, high performance cement-based composites (HPFRC) are used in the outer layer of the new type wall panel. FRP bars are used as the interface connector. Through experiments and analysis, the influence of the arrangement of connectors on the mechanical behaviors of thin-walled composite wall panel and the panel with window openings under two working conditions are investigated. The failure modes and the role of connectors of thin-walled composite wallboard are analyzed. The influence of the thickness of the wall layer and their combination on the strain growth of the control section, the initial crack resistance, the ultimate bearing capacity and the deformation of the wall panels are analyzed. The research work provides a technical reference for the engineering design of the light-weight thin-walled and durable composite sandwich wall panel.

Investigation of damaged formwork timber beam retrofitting with anchoraged CFRP strip under different loading

  • Abdullah TURER;Ozgur ANIL;Abdulkadir CEVIK;R. Tugrul Erdem
    • Steel and Composite Structures
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    • v.50 no.6
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    • pp.689-703
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    • 2024
  • Construction of high-rise structures, formwork systems that can be installed quickly, resistant to external loads, can be used more than once, have become a necessity. Timber and composite timber materials are preferred in the formation of such formwork systems due to their durability, ease of assembly, light weight and easy to use more than one time. Formwork beams are the most commonly used structural component in the formation of such formwork systems, and these beams can be damaged for different reasons during their lifetime. In this study, H20 top P type timber formwork beams with 1800 and 2450 mm length which is among the products of DOKA(c) company is damaged under the effect of static loading up to a high load level of 85% of the maximum ultimate capacity and after being retrofitted using anchored CFRP strips, performance and behavior of the beams under the influence of various loading types such as static, fatigue and impact are investigated experimentally. Two different lengths of retrofitted timber formwork beams were tested by applying monotonic static, fatigue and impact loading and comments were made about the effects of the retrofit method on performance under different loading types.

Transparent and Flexible All-Organic Multi-Functional Sensing Devices Based on Field-effect Transistor Structure

  • Trung, Tran Quang;Tien, Nguyen Thanh;Seol, Young-Gug;Lee, Nae-Eung
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.491-491
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    • 2011
  • Transparent and flexible electronic devices that are light-weight, unbreakable, low power consumption, optically transparent, and mechanical flexible possibly have great potential in new applications of digital gadgets. Potential applications include transparent displays, heads-up display, sensor, and artificial skin. Recent reports on transparent and flexible field-effect transistors (tf-FETs) have focused on improving mechanical properties, optical transmittance, and performances. Most of tf-FET devices were fabricated with transparent oxide semiconductors which mechanical flexibility is limited. And, there have been no reports of transparent and flexible all-organic tf-FETs fabricated with organic semiconductor channel, gate dielectric, gate electrode, source/drain electrode, and encapsulation for sensor applications. We present the first demonstration of transparent, flexible all-organic sensor based on multifunctional organic FETs with organic semiconductor channel, gate dielectric, and electrodes having a capability of sensing infrared (IR) radiation and mechanical strain. The key component of our device design is to integrate the poly(vinylidene fluoride-triflouroethylene) (P(VDF-TrFE) co-polymer directly into transparent and flexible OFETs as a multi-functional dielectric layer, which has both piezoelectric and pyroelectric properties. The P(VDF-TrFE) co-polumer gate dielectric has a high sensitivity to the wavelength regime over 800 nm. In particular, wavelength variations of P(VDF-TrFE) molecules coincide with wavelength range of IR radiation from human body (7000 nm ~14000 nm) so that the devices are highly sensitive with IR radiation of human body. Devices were examined by measuring IR light response at different powers. After that, we continued to measure IR response under various bending radius. AC (alternating current) gate biasing method was used to separate the response of direct pyroelectric gate dielectric and other electrical parameters such as mobility, capacitance, and contact resistance. Experiment results demonstrate that the tf-OTFT with high sensitivity to IR radiation can be applied for IR sensors.

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Effect of Seed Coat Color and Seed Weight on Protein, Oil and Fatty Acid Contents in Seeds of Soybean (Glycine max (L.) Merr.) Germplasms

  • Yu-Mi Choi;Hyemyeong Yoon;Myoung-Jae Shin;Yoonjung Lee;On Sook Hur;XiaoHan Wang;Kebede Taye Desta
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2021.04a
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    • pp.15-15
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    • 2021
  • Seed coat color and seed weight are among the key agronomical traits that determine the nutritional quality of soybean seeds. This study aimed to evaluate the contents of total protein, total oil and five prominent fatty acids in seeds of 49 soybean varieties recently cultivated in Korea, and assess the influences of seed coat color and seed weight on each. Total protein and total oil contents were in the ranges of 36.28-44.19% and 13.45-19.20%, respectively. Likewise, individual fatty acid contents were in the ranges of 9.90-12.55, 2.45-4.00, 14.97-38.74, 43.22-60.26, and 5.37-12.33% for palmitic, stearic, oleic, linoleic, and linolenic acids, respectively. Our results found significant variations of protein, oil and fatty acid contents between the soybean varieties. Moreover, both seed coat color and seed weight significantly affected total oil and fatty acid contents. Total protein content, however, was not significantly affected by any factor. Among colored soybeans, pale-yellow soybeans were characterized by a high level of oleic acid (30.70%) and low levels of stearic (2.72%), linoleic (49.30%) and linolenic (6.44%) acids, each being significantly different from the rest of colored soybeans (p < 0.05). On the other hand, small soybeans were characterized by high levels of all individual fatty acids except oleic acid. The level of oleic acid was significantly high in large seeds. Cluster analysis grouped the soybeans into two classes with notable content differences. Principal component analysis also revealed fatty acids as the prime factors for the variability observed among the soybean varieties. As expected, total oil and total protein contents showed a negative association with each other (r = -0.714, p < 0.0001). Besides, oleic acid and linoleic acid showed a tradeoff relationship (r = -0.936, p < 0.0001) which was reflected with respect to both seed coat color and seed weight. In general, the results of this study shade light on the significance of seed coat color and seed weight to distinguish soybeans in terms of protein, oil and fatty acid contents. Moreover, the soybean varieties with distinct characteristics and nutritional contents identified in this study could be important genetic resources for consumption and cultivar development.

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A Study on Selective Composite Patch for Light Weight and Quality Improvement of Battery Module (배터리 모듈의 경량화 및 품질 향상을 위한 선택적 복합재료 패치에 관한 연구)

  • Lee, Seung-Chan;Ha, Sung Kyu
    • Composites Research
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    • v.32 no.1
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    • pp.13-20
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    • 2019
  • In this study, in order to improve the quality issue and component characteristics of the battery module, which is one of the major parts of the electric vehicle. The structure is reinforced by using the composite material and the mechanism structure optimization of Hybrid concept which can overcome the disadvantages of single material was performed and the performance was compared. For this purpose, figure out the main design variables of composite materials according to Classical Laminated Plate Theory (CLPT) and the algorithm for predicting composite material properties have been studied. Based on the mechanical properties of the designed composite materials, finite element analysis (FEM) and the performance of the battery module was verified. Consequently, according to the verification result, Hybrid Battery Module reinforced with Selective Composite Patch can reduce the weight by 30% and reduce the product thickness by 32.5% compared with the existing Al battery module and proved the merit of Hybrid structure such as maintaining impact performance.

Effects of Temperature, Light Intensity and Soil Moisture on Growth, Yield and Essential Oil Content in Valerian(Valeriana fauriei var. dasycarpa Hara) (쥐오줌풀의 생육 및 수량과 정유성분에 미치는 온도, 광도, 토양수분의 영향)

  • Cho, Chang-Hwan;Lee, Jong-Chul;Choi, Young-Hyun;Han, Ouk-Kyu
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.42 no.1
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    • pp.22-32
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    • 1997
  • This experiment was conducted to obtain information for the cultivation of Korean valerian(Valeriana lauriei var. dasycarpa Hara) which will be useful for medicinal and aromatic resources. The effect of different temperature conditions, light intensities and soil water conditions on growth, yield and component of essential oil of V. fauriei were measured at the Dankook University, Cheonan, and a study on the shading treatment was at Umsung, Chungchongbukdo, and Jinbu, Kangwondo, in 1995. V. laudei was planted at five different temperature conditions, 10, 15, 20, 25 and 3$0^{\circ}C$, eight light intensity conditions, 1, 000, 2, 500, 5, 000, 20, 000, 30, 000, 40, 000, 50, 000 and 60, 000lux, six soil water contents, 30, 45, 55, 70, 80 and 90% of the saturated soil, during growth stage. Shading treatment was three conditions, 0, 25 and 50%, during the daytime in field conditions. Photosynthesis had a highly significant relationship with temperature conditions in a quadratic regression model, from which the temperature for the plant growth was estimated to be 17.7$^{\circ}C$. A highly significant quadratic regression was noted between temperature and leaf width or root weight of V. fauriei. It was estimated from the regression equation that the optimum temperature for root growth was 20.3$^{\circ}C$. The content of essential oil and extract rate of root was the highest in the 15~2$0^{\circ}C$. Photosynthesis also was significantly affected by light intensity in a quadratic regression model, from which the optimum light intensity for the growth was estimated to be 40, 000lux. Root yield was more produced in Jinbu than that of in Umsung. The root yield was increased by the shading treatment in Umsung, whereas it was decreased by the shading treatment in Jinbu. The content of essential oil was not affected by the shading treatment of plants during the cultivation, while the compositions of components of essential oil were related to the growing locations. As soil water content was higher, the growth and content of root extract were increased. The optimum soil moisture for the growth of V. fauriei was 80~90% of the saturated soil. In summary, the results indicated that the growth, yield and component of essential oil in V. fauriei were affected by environmental factors as well as soil moisture.

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Positron Annihilation Spectroscopy of Active Galactic Nuclei

  • Doikov, Dmytry N.;Yushchenko, Alexander V.;Jeong, Yeuncheol
    • Journal of Astronomy and Space Sciences
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    • v.36 no.1
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    • pp.21-33
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    • 2019
  • This paper focuses on the interpretation of radiation fluxes from active galactic nuclei. The advantage of positron annihilation spectroscopy over other methods of spectral diagnostics of active galactic nuclei (therefore AGN) is demonstrated. A relationship between regular and random components in both bolometric and spectral composition of fluxes of quanta and particles generated in AGN is found. We consider their diffuse component separately and also detect radiative feedback after the passage of high-velocity cosmic rays and hard quanta through gas-and-dust aggregates surrounding massive black holes in AGN. The motion of relativistic positrons and electrons in such complex systems produces secondary radiation throughout the whole investigated region of active galactic nuclei in form of cylinder with radius R= 400-1000 pc and height H=200-400 pc, thus causing their visible luminescence across all spectral bands. We obtain radiation and electron energy distribution functions depending on the spatial distribution of the investigated bulk of matter in AGN. Radiation luminescence of the non-central part of AGN is a response to the effects of particles and quanta falling from its center created by atoms, molecules and dust of its diffuse component. The cross-sections for the single-photon annihilation of positrons of different energies with atoms in these active galactic nuclei are determined. For the first time we use the data on the change in chemical composition due to spallation reactions induced by high-energy particles. We establish or define more accurately how the energies of the incident positron, emitted ${\gamma}-quantum$ and recoiling nucleus correlate with the atomic number and weight of the target nucleus. For light elements, we provide detailed tables of all indicated parameters. A new criterion is proposed, based on the use of the ratio of the fluxes of ${\gamma}-quanta$ formed in one- and two-photon annihilation of positrons in a diffuse medium. It is concluded that, as is the case in young supernova remnants, the two-photon annihilation tends to occur in solid-state grains as a result of active loss of kinetic energy of positrons due to ionisation down to thermal energy of free electrons. The single-photon annihilation of positrons manifests itself in the gas component of active galactic nuclei. Such annihilation occurs as interaction between positrons and K-shell electrons; hence, it is suitable for identification of the chemical state of substances comprising the gas component of the investigated media. Specific physical media producing high fluxes of positrons are discussed; it allowed a significant reduction in the number of reaction channels generating positrons. We estimate the brightness distribution in the ${\gamma}-ray$ spectra of the gas-and-dust media through which positron fluxes travel with the energy range similar to that recorded by the Payload for Antimatter Matter Exploration and Light-nuclei Astrophysics (PAMELA) research module. Based on the results of our calculations, we analyse the reasons for such a high power of positrons to penetrate through gas-and-dust aggregates. The energy loss of positrons by ionisation is compared to the production of secondary positrons by high-energy cosmic rays in order to determine the depth of their penetration into gas-and-dust aggregations clustered in active galactic nuclei. The relationship between the energy of ${\gamma}-quanta$ emitted upon the single-photon annihilation and the energy of incident electrons is established. The obtained cross sections for positron interactions with bound electrons of the diffuse component of the non-central, peripheral AGN regions allowed us to obtain new spectroscopic characteristics of the atoms involved in single-photon annihilation.

Effects of Media Replacement and Environmental Control for in vitro Microtuber Production of Yam (Dioscorea opposita Thunb.) (둥근마(Dioscorea opposita Thunb.) 기내 소괴경 생산을 위한 배양환경과 배지의 교체효과)

  • Jeong, Eun-Ah;Jeong, Jeong-Hak;Kwon, Soon-Tae
    • Korean Journal of Plant Resources
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    • v.25 no.2
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    • pp.225-231
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    • 2012
  • To figure out optimum culturing condition for $in$ $vitro$ yam ($Dioscorea$ $opposita$ Thunb.) production, various media components and environmental controls were evaluated, effective temperature, light condition and timing of the liquid media replacement for multiplication of yam in liquid culture were determined in this study. There was no visible difference detected for $15^{\circ}C$ and $25^{\circ}C$ temperature conditions. At $25^{\circ}C$, continuous light condition was more effective compared to 16 hour light/ 8 hour dark condition. Effect of media replacement was tested, and approximately 5 more microtubers obtained and 70% of increase in weight was detected when media replacement was performed. Timing for media replacement was tested at 2, 4, 6, 8, and 10 weeks after initial culture for 12 weeks. Considering both number and weight of microtubers, replacement of media 6 weeks after initial culture was most effective. In terms of component of media, significant increase in weight of microtubers was observed in MS media containing sucrose $60g{\cdot}L^{-1}$. In summary, the most effective condition for $in$ $vitro$ propagation of chinese yam is replacing medium 6 weeks after initial inoculation with MS medium containing sucrose $60g{\cdot}L^{-1}$ in continuous light condition.

Analysis of Littoral Currents by the Coupled Hydrodynamic Model (복합해수유동 수치모형에 의한 조간대 연안류의 해석)

  • Lee, Jong-Sup;Kwon, Kyong-Hwan;Park, Il-Heum
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.20 no.2
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    • pp.247-258
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    • 2014
  • To evaluate the influence of the external force components on the littoral currents in the Gusipo beach, Jeonbuk, West Coast of Korea where a wide tidal sand flat developed, a coupled hydrodynamic model considered real time tidal currents and wave-induced currents was constructed in which the EFDC for tides and tidal currents, the SWAN for waves and the SHORECIRC for wave-induced currents were used as the hindcasting models. A series of field observations for tides, tidal currents and incident waves were carried out and especially to observe the littoral currents in the tidal sand flat, the GPS mounted and light weight drogues were used. Also wind data were collected from the adjacent weather station. To analyze the littoral current components, the numerical drogue tracking results considered real time winds, tides and waves were compared with the field drogue data. The drift speed of numerical drogues was reproduced as the range of 68.0~105.2% compared with the field data and the velocity error of main direction component showed a good result as -16.7~10.0%. As a result, in the mild slope tidal flat including wide surf zone, the tides and winds were the major affection component of the littoral currents, on the other hand, the wave-induced currents seemed the minor component when the incident wave heights were relatively small.