• Title/Summary/Keyword: lifetime diagnostics

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The Bivariate Kumaraswamy Weibull regression model: a complete classical and Bayesian analysis

  • Fachini-Gomes, Juliana B.;Ortega, Edwin M.M.;Cordeiro, Gauss M.;Suzuki, Adriano K.
    • Communications for Statistical Applications and Methods
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    • v.25 no.5
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    • pp.523-544
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    • 2018
  • Bivariate distributions play a fundamental role in survival and reliability studies. We consider a regression model for bivariate survival times under right-censored based on the bivariate Kumaraswamy Weibull (Cordeiro et al., Journal of the Franklin Institute, 347, 1399-1429, 2010) distribution to model the dependence of bivariate survival data. We describe some structural properties of the marginal distributions. The method of maximum likelihood and a Bayesian procedure are adopted to estimate the model parameters. We use diagnostic measures based on the local influence and Bayesian case influence diagnostics to detect influential observations in the new model. We also show that the estimates in the bivariate Kumaraswamy Weibull regression model are robust to deal with the presence of outliers in the data. In addition, we use some measures of goodness-of-fit to evaluate the bivariate Kumaraswamy Weibull regression model. The methodology is illustrated by means of a real lifetime data set for kidney patients.

Study of Optimal Conditions Affecting the Photothermal Effect and Fluorescence Characteristics of Indocyanine Green

  • Seo, Sung Hoon;Bae, Min Gyu;Park, Hyeong Ju;Ahn, Jae Sung;Lee, Joong Wook
    • Current Optics and Photonics
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    • v.5 no.5
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    • pp.554-561
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    • 2021
  • Indocyanine green (ICG) is a cyanine dye that has been used in medical diagnostics based on fluorescence imaging, and in medical therapy based on the photothermal effect. It is important to systematically understand the photothermal effect and fluorescence characteristics of ICG simultaneously. By varying a number of conditions such as laser power density, laser irradiation wavelength, concentration of ICG solution, and exposure time of laser irradiation, the intensity properties of fluorescence and the temperature change induced by the photothermal effect are measured simultaneously using a charge-coupled-device camera and a thermal-imaging camera. The optimal conditions for maximizing the photothermal effect are determined, while maintaining a relatively long lifetime and high efficiency of the fluorescence for fluorescence imaging. When the concentration of ICG is approximately 50 ㎍/ml and the laser power density exceeds 1.5 W/cm2, the fluorescence lifetime is the longest and the temperature induced by the photothermal effect rapidly increases, exceeding the critical temperature sufficient to damage human cells and tissues. The findings provide useful insight into the realization of effective photothermal therapy, while also specifying the site to be treated and enabling real-time treatment monitoring.

Halide Perovskites for X-ray Detection: The Future of Diagnostic Imaging

  • Nam Joong Jeon;Jung Min Cho;Jung-Keun Lee
    • Progress in Medical Physics
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    • v.33 no.2
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    • pp.11-24
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    • 2022
  • X-ray detection has widely been applied in medical diagnostics, security screening, nondestructive testing in the industry, etc. Medical X-ray imaging procedures require digital flat detectors operating with low doses to reduce radiation health risks. Recently, metal halide perovskites (MHPs) have shown great potential in high-performance X-ray detection because of their attractive properties, such as strong X-ray absorption, high mobility-lifetime product, tunable bandgap, low-temperature fabrication, near-unity photoluminescence quantum yields, and fast photoresponse. In this paper, we review and introduce the development status of new perovskite X-ray detectors and imaging, which have emerged as a new promising high-sensitivity X-ray detection technology. We discuss the latest progress and future perspective of MHP-based X-ray detection in medical imaging. Finally, we compare the conventional detection methods with quantum-enhanced detection, pointing out the challenges and perspectives for future research directions toward perovskite-based X-ray applications.

Ultrasound-optical imaging-based multimodal imaging technology for biomedical applications (바이오 응용을 위한 초음파 및 광학 기반 다중 모달 영상 기술)

  • Moon Hwan Lee;HeeYeon Park;Kyungsu Lee;Sewoong Kim;Jihun Kim;Jae Youn Hwang
    • The Journal of the Acoustical Society of Korea
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    • v.42 no.5
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    • pp.429-440
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    • 2023
  • This study explores recent research trends and potential applications of ultrasound optical imaging-based multimodal technology. Ultrasound imaging has been widely utilized in medical diagnostics due to its real-time capability and relative safety. However, the drawback of low resolution in ultrasound imaging has prompted active research on multimodal imaging techniques that combine ultrasound with other imaging modalities to enhance diagnostic accuracy. In particular, ultrasound optical imaging-based multimodal technology enables the utilization of each modality's advantages while compensating for their limitations, offering a means to improve the accuracy of the diagnosis. Various forms of multimodal imaging techniques have been proposed, including the fusion of optical coherence tomography, photoacoustic, fluorescence, fluorescence lifetime, and spectral technology with ultrasound. This study investigates recent research trends in ultrasound optical imaging-based multimodal technology, and its potential applications are demonstrated in the biomedical field. The ultrasound optical imaging-based multimodal technology provides insights into the progress of integrating ultrasound and optical technologies, laying the foundation for novel approaches to enhance diagnostic accuracy in the biomedical domain.

Neural Network Model for Partial Discharge Pattern Analysis of XLPE/EPR Interface (XLPE/EPR 계면의 부분방전 패턴 분석을 위한 신경망 모형)

  • Cho, Kyung-Soon
    • Journal of the Korea Computer Industry Society
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    • v.6 no.2
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    • pp.357-364
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    • 2005
  • The prefabricated type used generally in Korea to join cable runs on new installations or to repair broken Cable runs on existing installations, because installation is very simple and save time. This type is a permanent, shielded and submersible cable joint for direct burial or vault application. It confirms to the requirements of IEEE std. 404-1993 by factory testing, but many problems of insulated cable systems are caused by internal defects of the joint part which have to be mounted ensile. Faults arise from impurities or voids. A suitable solution for a monitoring of cable joints during the after-laying test and service is partial discharge detection. Specimen obtained 1mm thickness from the insulation of real power cable and cable joint. <중략>The partial discharges are measured to determine their time dependence for 60 minutes and the influence of applied electrical stress under 30kV. $\Phi-q-n$ properties were measured using detection impedance, high pass filter and computerized data acquisition system. Statistic Value like maximum charge, repetition rate, average charge, etc. are calculated. It is possible to quantitative analysis of $\Phi-q-n$ properties from this statistic value and pattern analysis.

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Neural Network Model for Partial Discharge Pattern Analysis of XLPE/EPR Interface (XLPE/EPR 계면의 부분방전 패턴 분석을 위한 신경망 모형)

  • Cho Kyung-Soon
    • Journal of the Korea Computer Industry Society
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    • v.6 no.2
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    • pp.279-286
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    • 2005
  • The prefabricated type used generally in Korea to join cable runs on new installations or to repair broken Cable runs on existing installations, because installation is very simple and save time. This type is a permanent, shielded and submersible cable joint for direct burial or vault application. It confirms to the requirements of IEEE std. 404-1993 by factory testing, but many problems of insulated cable systems are caused by internal defects of the joint part which have to be mounted ensile. Faults arise from impurities or voids. A suitable solution for a monitoring of cable joints during the after-laying test and service is partial discharge detection. <중략> $\Phi-q-n$ properties were measured using detection impedance, high pass filter and computerized data acquisition system. Statistic Value like maximum charge, repetition rate, average charge, etc. are calculated. It is possible to quantitative analysis of $\Phi-q-n$ properties from this statistic value and pattern analysis.

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Assessment of Perception of Medical Students in Regard to Links between Tobacco or Alcohol Use and Cancer

  • Alshammari, Fawaz Dabea;Khalifa, Amany M;Kosba, Ayman Ahmed;Khalil, Nuhar A;Ali, Safia M;Hassouna, Mona M;Elawad, Gamal Mohamed;Ginaw, Ibrahim Abdelmajeed;Ahmed, Hussain Gadelkarim
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2697-2700
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    • 2015
  • Background: The aim of this study was to assess cancer awareness among medical students in Saudi Arabia toward tobacco and alcohol use as risk factors. Materials and Methods: A cross-sectional survey from October to December 2014, covering 1200 medical students, was performed. Results: Of the total, 975 (81.25%) responded. The male to female ratio was 1.00:7.125. 96/975 (9.8%) had smoked tobacco in their lifetime, and 51/975 (5.23%) were alcoholic beverage consumers. On asking them whether tobacco smoking and alcohol consumption can cause cancer, only 4/975 (0.4%) and 14/975 (1.43%) answered no for smoking and alcohol, respectively. Conclusions: The prevalence of smoking and alcohol use is very low among medical students, which might be due to high female contribution besides social stigma. The prevalence of second-hand smoke (SHS) was found to be very high in Hail region.

Experimental Study of Operating Parameters for Pneumatic Control Valve in Abnormal Conditions (공기구동 제어밸브 비정상상태 운전변수에 관한 실험적 연구)

  • Kim, Yang-seok;Kim, Dae-woong;Lee, Byoung-oh;Jeoung, Rae-hyuk;Lee, Seung-ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.6
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    • pp.613-619
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    • 2016
  • A pneumatic control valve performs a major role in controlling the flow of a system or the level of a key tank in many power plants, and its performance should be guaranteed during the plant's lifetime. Its operation starts by supplying air to the pneumatic actuator or by exhausting the air from the actuator. To control the valve position, the amount of air supply or exhaust is adjusted by a control loop where various accessaries are equipped. In this paper, air leakage in the air supply line, changes in the valve packing force, and false adjustments of zero and the span of the positioner are simulated and analyzed using a 2-in pneumatic valve with a position control loop including an I/P converter and positioner, where the valve position is controlled within ${\pm}2%$ of the control pressure at 67% opening position.