• Design & Manufacturing
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• v.18 no.3
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• pp.30-36
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• 2024

As the demand for biomaterials and medical devices increases due to advancements in medical technology and the rising average lifespan of the population, the importance of surface treatment technology for biometallic materials used in orthopedic implants is highlighted. Achieving stable mechanical attachment between the implant and human bone, specifically bone cell adhesion, is crucial. Without proper adhesion, issues such as inflammation and reduced load-bearing capacity can occur, leading to the need for implant reimplantation. Therefore, this paper focuses on creating a micro-groove pattern using a pulsed nanosecond laser on the surface of a titanium alloy (Ti6Al4V), a biometallic material, to promote cell adhesion. To evaluate the effectiveness of the pattern in enhancing cell adhesion, MG-63 osteoblasts were cultured on the micro-groove patterned surface, and their adhesion and morphological changes were analyzed. This study confirms the potential of laser processing as a surface treatment method for biometallic materials.

• Journal of the korean society of oceanography
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• v.34 no.1
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• pp.1-21
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• 1999

A two-layer quasi-geostrophic numerical model is used to investigate the temporal variability of the East Korea Warm Current (EKWC), especially the separation from the Korean coast and the generation of warm eddies. An attention is given on the active role of the nonlinear boundary layer process. For this, an idealized flat bottom model of the East Sea is forced with the annual mean wind curl and with the inflow-outflow specified at the Korea (Tsushima) and Tsugaru Straits. Two types of separation mechanisms are identified. The first one is influenced by the westward movement of the recirculating leg of the EKWC (externally driven separation),the second one is solely driven by the boundary layer dynamics (internally driven separation). However, these two processes are not independent, and usually coexist. It is hypothesized that 'internally driven separation' arises as the result of relative vorticity production at the wall, its subsequent advection via the EKWC, and its accumulation up to a critical level characterized by the separation of the boundary flow from the coast. It is found that the sharp southeastern corner of the Korean peninsula provides a favorable condition for the accumulation of relative vorticity. The separation of the EKWC usually accompanies the generation of a warm eddy with a diameter of about 120 km. The warm eddy has a typical layer-averaged velocity of 0.3 m/s and its lifespan is up to a year. In general, the characteristics of the simulated warm eddy are compatible with observations. A conclusion is therefore drawn that the variability of the EKWC is at least partially self-excited, not being influenced by any sources of perturbation in the forcing field, and that the likely source of the variability is the barotropic instability although the extent of contribution from the baroclinic instability remains unknown. The effects of the seasonal wind curl and inflow-outflow strength are also investigated.

• Journal of the Korean institute of surface engineering
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• v.48 no.2
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• pp.33-37
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• 2015

High efficiency LED device is being concerned due to its high heat loss, and such heat loss will cause a shorter lifespan and lower efficiency. Since there is a demand for the materials that can release heat quickly into the external air, the organic insulating layer was required to be replaced with high thermal conductive materials such as metal or ceramics. Through anodizing the upper layer of Al, the Breakdown Voltage of 3kV was obtained by using an uniform thickness of $60{\mu}M$ aluminum oxide($Al_2O_3$) and was carried out to determine the optimum process conditions when thermal cracking does not occur. Two Ni layers were formed above the layer of $Al_2O_3$ by sputtering deposition and electroplating process, and saccharin was added for the purpose of minimizing the remain stress in electroplating process. The results presented that the 3-layer film including the Ni layer has an adhesive force of 10N and the thermal conductivity for heat dissipation is achieved by 150W/mK level, and leads to improvement about 7 times or above in thermal conductivity, as opposed to the organic insulation layer.

• Journal of Life Science
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• v.30 no.9
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• pp.819-825
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• 2020

All living organisms exhibit the characteristics of aging, such as skin wrinkle formation, muscle degeneration, cataracts, and hair graying as the number of aged cells increases over time. Senescence, which is known as a key cause of aging, is directly related to the aging of living organisms because cells are aged by external and internal factors and eventually cell proliferation is stopped. Senescence is caused by the gradual shortening of the telomere with cell division, and lifespan is determined by the length of the telomere. Recently, it has been found that the histone deacetylase, which can influence gene expression, is not only involved in yeast but also deeply involved in anti-aging mechanisms in both C. elegans and humans. It was also discovered that old cells play a decisive role in the aging phenomenon, and it has been reported that it is possible to promote the proliferation of young cells and delay aging by removing these senescent cells from the inside. Therefore, in order to develop potential anti-aging agents in the future, research should begin with an in-depth study of telomerase activators, sirtuin activators, and senolytics.

• Journal of Ecology and Environment
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• v.41 no.3
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• pp.66-71
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• 2017

Background: The sprouts of oak species play an important role in maintaining the oak community in a disturbed environment. In this study, we cut 1-year-old oak in three times during the 3 years and measured the sprout responses to know sprouting ability of six deciduous oaks in Korea. Results: Oak sprouts have appeared in spring and fall, and some of the sprouts had lifespan as short as a month. As the number of cutting increases, sprout number of Quercus acutissima increased whereas the other oak species decreased or died. The average number of sprouts over the 3 years was from 1.4 (Quercus mongolica) to 2.2 (Q. acutissima) per individual. Quercus serrata died after the second cutting, and Quercus dentata died after the third cutting. So, the two species have the lowest sprouting ability among six oak species. The sprouts grew actively during fall and slowly in summer. The sprout length during the 3 years was in the following descending order: Q. acutissima, Quercus aliena, Q. dentata, and Q. mongolica. Sprout of Q. acutissima and Q. aliena generated steadily over the 3 years, and sprout of Quercus variabilis and Q. mongolica was changed by year. After the 3 years, the number of sprouts increased only in Q. acutissima but sprout number of the other five oak species decreased. The sprout length of Q. acutissima, Q. aliena, and Q. variabilis increased, but sprout length of the other three oak species decreased. The average survival rate of saplings over the 3 years was in the following descending order: Q. acutissima, Q. aliena, Q. variabilis, and Q. mongolica. Conclusions: As a result, the sprouting ability of Q. acutissima was the highest. Such level of sprouting ability may be the evidence of how Q. acutissima community exists as a dominant species in a disturbed environment in lowlands of Korea peninsula.

• Journal of the Korea Convergence Society
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• v.7 no.6
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• pp.167-176
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• 2016

The purpose of this study was to investigate the influence of attachment across an individual's lifespan. The present study explored how mother attachment in childhood influences adult student's major satisfaction and examined the mediating effect of self-esteem between mother attachment and major satisfaction. Participants were 529 adult students enrolled in S Cyber University. They answered a questionnaire about their present self-esteem level, attachment to their mother in childhood, and major satisfaction. By using SEM analysis, this study found that adult students' self-esteem completely mediated between their childhood attachment to their mother and their major satisfaction in adulthood. This result indicates influences of a secure attachment and positive self-esteem on major satisfaction of e-learning adult students.

• The Journal of the Korea Contents Association
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• v.9 no.12
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• pp.357-363
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• 2009

The current population of elderly is increasing and the with an extended average lifespan, the frequency of cancerous occurrences have also increased, with these increases and the increase in radiotherapy for cancer patients, recognitions of harm and importance have become known. This article was known tumor treatment of patients with hematopoietic disorder by doing a comparative study on the changes in blood cells caused by the acute effects of trace dose to high dose of radiation exposed to mice. According to the sensitizer injection may give rise to harm to the components of peripheral blood. This material needs to be considered when for treating tumor patients and the risks of hematopoietic harm and believe that radiation therapy will be reasonable.

• Reproductive and Developmental Biology
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• v.31 no.2
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• pp.127-131
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• 2007

Embryonic germ (EG) cells are undifferentiated stern cells isolated from cultured primordial germ cells (PGC). These cells share many characteristics with embryonic stem cells including morphology and pluripotency. Undifferentiated porcine EG cell lines demonstrating capacities of differentiation both in vitro and in vivo have been established. Since EG cells can be cultured indefinitely in an undifferentiated state, whereas somatic cells in primary culture are often unstable and have limited lifespan, EG cells may provide inexhaustible source of karyoplasts in nuclear transfer (NT). In this study the efficiencies of NT using porcine EG and fetal fibroblast cells were compared. Two different techniques were used to perform NT. With conventional NT procedure (Roslin method) involving fusion of donor cells with enucleated oocytes, the rates of development to the blastocyst stage in EG and somatic cell NT were 16.8% (59/351) and 14.5% (98/677), respectively. In piezo-driven microinjection (Honolulu method) of donor nuclei into enucleated oocytes, the rates of blastocyst formation in EG and somatic cell NT were 11.9% (15/126) and 9.4% (9/96), respectively. Regardless of NT methods used in this study, EG cell NT gave rise to comparable rate of blastocyst development to somatic cell NT. Overall, EG cells can be used as karyoplast donor in NT procedure, and embryos can be produced by EG cell NT that may be used as an alternative to conventional somatic cell NT.

• Genomics & Informatics
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• v.10 no.2
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• pp.106-109
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• 2012

Pulse rate is known to be related to diverse phenotypes, such as cardiovascular diseases, lifespan, arrhythmia, hypertension, lipids, diabetes, and menopause. We have reported two genomewide significant genetic loci responsible for the variation in pulse rate as a part of the Korea Association Resource (KARE) project, the genomewide association study (GWAS) that was conducted with 352,228 single nucleoride polymorphisms typed in 8,842 subjects in the Korean population. GJA1 was implied as a functionally causal gene for pulse rate from the KARE study, but lacked evidence of replication. To re-evaluate the association of a locus near GJA1 with pulse rate, we looked up this signal in another GWAS conducted in a Health Examinee-shared cohort of 3,703 samples. Not only we were able to confirm two pulse rate loci (1q32.2a near CD46 and 6q22.13c near LOCL644502) identified in the KARE GWAS, we also replicated a locus (6q22.31c) near GJA1 by the lookup in the Health Examinee GWAS. Considering that the GJA1-encoded protein is a major component of cardiac gap junctions, a functional study might be necessary to validate its genuine molecular biological role in the synchronized contraction of the heart.

• Journal of the Korea Fashion and Costume Design Association
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• v.19 no.2
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• pp.1-14
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• 2017

The consumption trend of fashion in modern industrial society is developing from the rapid changes, and the lifespan of fashion products becomes shorter due to the various industrial wastes. Due to the attitude change caused by the ethical consumption consciousness and environment awareness, the up-cycle fashion products got to receive attention, and it is in the limelight as a new trend to realize the sustainable fashion products in the domestic and foreign fashion. The purpose of this study lies in drawing the expression characteristics by investigating and analyzing the cases of each type on the fashion bag products of up-cycle brand, and contributing to the diversification of product family fitting to the characteristics of fashion bag product of up-cycle brand, systematic strategies of up-cycle fashion products, and activation of up-cycle fashion market. In research methods, the theatrical researches were conducted centered the relevant domestic literature materials, preceding papers, etc., which ran paralleled with the actual case analysis study. Through the preceding research and websites related to selected products, websites of up-cycle companies, relevant books, related articles, etc., the expression characteristics of up-cycle fashion bag products were drawn. The results of this study are as follows: First, as it has the feature of historicality, the designs can be created by containing the designer's story, story of materials, and consumer's story. Second, since it has the characteristic of sustainability, the application of manufacturing process and materials, extension of product life, conversion of original material's function, etc. can be sustainable. Third, as it's a trait of scarcity, all products may be produced by hand, and it can have the specialty which the original materials have. Fourth, since it has an eco-friendly trait, even while saving the original materials, the aesthetic needs could be met according to the consumers' continuous demand.