• 한국산학기술학회논문지
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• 제18권5호
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• pp.190-199
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• 2017

의료 기술의 발달로 수명이 연장됨으로써 노년기에 어떻게 행복한 생활을 영위할 수 있는지에 대한 관심이 커지고 있다. 그런데 연령대에 따라 행복감에 영향을 미치는 변인의 유형이나 행복에 대한 변인의 영향력이 변화할 수 있기 때문에 이에 대해 실증적으로 조사하는 연구가 필요하다. 선행연구를 통해 조절초점 중 '향상초점'을 활용하는 개인이 '방어초점'을 활용하는 개인보다 대체로 행복할 가능성이 높다는 것이 발견되었다. 그러나 이와 같은 조절초점의 영향이 사람의 전생애동안 모든 연령대에 걸쳐서 유효한 것인지에 대해서는 아직 조사가 제대로 이루어지지 않았다. 따라서 본 연구에서는 거주지역과 연령대별로 성인 1250명을 무작위로 선정하여 표집을 구성하고 연령이 조절초점과 주관적 행복감 간의 관계에 대해 유의한 조절효과를 가지는지 검증하였다. 분석 결과, 향상초점과 연령은 주관적 행복감에 대해 유의한 상호작용 효과를 가진 것이 발견되었으나, 방어초점과 연령은 유의한 상호작용을 보이지 않는 것으로 나타났다. 보다 더 구체적으로 연령이 높아질수록 향상초점이 삶의 만족도와 정서균형에 미치는 정적 영향이 더 강해지는 것이 발견되었다. 본 연구결과는 노년기에 능동적으로 도전적인 목표를 설정하고, 자발적으로 동기를 부여하며 성취감을 느끼는 등 향상초점을 활용하는 것이 주관적 행복감을 경험하는 데 더 중요한 역할을 한다는 것을 시사한다. 또한 본 연구에서는 사회적 지원체제의 구축을 통해 노인의 향상초점을 활성화할 것을 제안한다.

• Korean Journal of Acupuncture
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• 제19권1호
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• pp.47-56
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• 2002

The frequency of the hypertension is increasing as the life level is improved and an average span of the life is extended since we approached modern stage. The hypertension is also dangerous disease which raises fatal complication for example with the bleeding aproplexy and the ischemic attack. The medicinal treatment about the hypertension is required patients to take continually. The acupuncture have been introduced because a medicine-chemical treatment hasn't good influence on the human body. It recently has been processed that studies acupuncture effect for blood pressure and have been found out that blood pressure go down. The object of this study observe the effect of LR3 acupuncture on hypertension in Renal Hypertension RAT induced by 2K1C. The 2K1C model was based on renin-angiotensin system. We put the silver clip in renal artery to induce renal hypertension. We try to observe that LR3 acupuncture influence on the blood pressure and c-fos expression in CVLM, NTS, RVLM. In results, the blood pressure was decreased during acupuncture than before acupuncture, after acupuncture. The heart rate was also decreased during acupuncture than before acupuncture, after acupuncture. The LR3 acupuncture significantly effects on blood pressure and heart rate (P<0.05). The increased expression of c-fos was shown in CVLM, NTS, but not in RVLM. In conclusion, LR3 was relived the action of control upon the hypertension and related with medulla, particularly CVLM, NTS. It needs to be closely examined pharmacological mechanism and studied combination with other acupoints.

• Journal of the Korean Wood Science and Technology
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• 제42권3호
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• pp.309-317
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• 2014

수확된 목제품(Harvested Wood Products, HWP)이란 제재목, 합판, 파티클보드 또는 목구조재, 건축내장재, 가구, 종이제품 등과 같이 나무를 원료로 사용하여 가공한 제품을 말한다. HWP는 수명을 다하여 폐기될 때까지 산림에서 생장하면서 저장했던 탄소를 장기간 제품 내에 저장하고 있기 때문에 대기 중의 이산화탄소 농도를 안정화시키는 효과를 발휘한다. 이러한 이유로, 탄소계정 시 목제품의 탄소저장효과를 인정해야 한다는 의견들이 지속적으로 제기되어왔다. 2011년 11월 더반에서 열린 17차 기후변화협약 당사국총회(COP)에서는 자국산 목재 만을 대상으로 하는 생산접근법을 HWP의 탄소계정방법으로 결정하였다. 이에 본 연구는 향후 국가 간 논의 및 협상에 대응하고자 국산 HWP 탄소계정에 필요한 인자인 반감기를 결정하기 위하여, 외국의 반감기 결정사례를 조사하고 국산 HWP 반감기 결정을 위해 필요한 요소를 분석하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2307-2310
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• 2013

Curcumin previously was proven to inhibit angiogenesis and display potent antitumor activity in vivo and in vitro. In the present study, we investigated whether a combination curcumin with hyperthermia would have a synergistic antitumor effect in the LL/2 model. The results indicated that combination therapy significantly inhibited cell proliferation of MS-1 and LL/2 in vitro. LL/2 experiment model also demonstrated that the combination therapy inhibited tumor growth and prolonged the life span in vivo. Furthermore, combination therapy reduced angiogenesis and increased tumor apoptosis. Our findings suggest that the combination therapy exerted synergistic antitumor effects, providing a new perspective fpr clinical tumor therapy.

• 셀메드
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• 제1권1호
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• pp.4.1-4.4
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• 2011

Excessive stress is harmful to academic performance in children and may lead to dropping out of school. To meet the demands of a modern life-style which is full of speed, stress and tension, an all-round child health program is crucial. The use of yoga for children has diverse applications in maintaining and developing their physical, mental, intellectual, emotional and spiritual levels. Yoga, through its physical postures (asana), breathing practices (pranayama), cleansing techniques (kriya), meditation therapies (dhyana) and relaxation training (yoga nidra) yields a positive effect in the management of stress in children. Yoga practice benefited children by improving their eye-hand coordination, attention span, levels of concentration, competitive performance and relaxation. Visually impaired children showed a significant decrease in their abnormal anxiety levels when they practiced yoga for three weeks, while a program of physical activity had no such effect. Socially disadvantaged children in a remand home showed significant improvements in sleep, appetite and general well being, as well as a decrease in physiological arousal after yoga. In one study, it is found that a 4-week program of asana and meditation lowers the aggressive behavior of children. Meditation helped to reduce problems related to maladaptive behavior, increase emotional and physical health and psychological well-being in children. Finally, the possible role of yoga in improving the mental state and general well-being of children with cancer is being explored.

• 대한약침학회지
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• 제13권1호
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• pp.5-14
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• 2010

Objectives : This study was performed to examine the anticancer effect of mountain ginseng Pharmacopuncture(MGP) to the nude mouse of lung carcinoma induced by NCI-H460 human nonsmall lung cancer cells. Methods : Human lung cancer (NCI-H460) cells were cultured and applied to evaluate anti-tumor activity in nude mice. After confirmed tumor growth in mice, MGP was treated per 0.1ml/kg dose to intraperitoneal and intravenous injection everyday for four weeks. And checked the changes in body weights, tumor volume, mean survival time and percent, increase in life span, histo-pathological findings, organ weights, and blood chemistry levels. Results : The results of in vivo study showed that MGP may have potential as growth inhibitor of solid tumor induced NCI-H460 without marked side effects. MGP inhibited dosage-dependently the growth of NCI-H460 cell-transplanted solid tumor compared with the control group. And mean survival time of MGP treated group was prolonged comparing with control group. Generally the group of intravenous injection is more effective than intraperitoneal injection. Conclusion : These results were suggested that MGP may be a useful anticancer agent for therapy of human lung cancer. And follow study need for the certain evidence.

• 한국미생물·생명공학회지
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• 제28권1호
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• pp.52-58
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• 2000

The effect of fivrinolytic enzyme produced from Bacillus subtilis K-54 on the thrombosis and stress in vivo was investigated. Each partially purified fibrinolytic enzyme of 4 protein casein unit was administered orally for 3 days before intravenously injection with collagen and epinephrine. In the mice group administered with the enzyme and increased life span of mice was observed in comparison with that of control. The result suggest that the enzyme may prevent the formation of thrombos in vivo. Administration of the enzyme did not influence to stress itself because 5-hydroxyindoleacetatic acid concentration of brain in the mice group with stress did not decreased after the administration of the enzyme. The value of lipid peroxide (LPO) of the liver and brain cells in the group treted with the enzyme was lower than that of control. However, protein degradation (PDP value showed no significant difference between treatment and control groups. In addition, the value of activated partial thromboplastin time (APTT), protrombin time (PT0 and antiplasmin in blood were higher in the stress group than that of the enzyme treated group.

• Natural Product Sciences
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• 제5권1호
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• pp.1-6
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• 1999

This study was devised to observe the antitumor activity of mugwort (Artemisia princeps Pampan.) against ICR mice inoculated with sarcoma-180 cells. The antitumor compounds were partially purified from petroleum ether extract of mugwort by silicic acid column chromatography. The active fraction used in in vivo test was obtained under the elution with acetone in silicic acid column chromatography. When the acetone fraction was intraperitoneally injected to the mice which had been subcutaneously inoculated on the left groin with sarcoma-180, the growth rate of tumor (sarcoma-180 mass) was inhibited by 30%. In case the acetone fraction was injected to the mice which had been inoculated intraperitoneally with sarcoma-180, the average life span was prolonged by 20%. After the injection of the active fraction, the spleen index and ${\gamma}-globulin$ ratio (%) were increased significantly (p<0.05). The administration of acetone fraction did not cause any abnormality in the body and the homeostasis of mice. Those observations suggest that the acetone fraction of mugwort extract has an antitumor effect in vivo.

• 대한간호학회지
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• 제42권4호
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• pp.537-548
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• 2012

Purpose: The purpose of this study was to use meta-analysis to evaluate the variables related to depression in patients who have had a stroke. Methods: The materials of this study were based on 16 variables obtained from 26 recent studies over a span of 10 years which were selected from doctoral dissertations, master's thesis and published articles. Results: Related variables were categorized into sixteen variables and six variable groups which included general characteristics of the patients, disease characteristics, psychological state, physical function, basic needs, and social variables. Also, the classification of six defensive and three risk variables group was based on the negative or positive effect of depression. The quality of life (ES=-.79) and acceptance of disability (ES=-.64) were highly correlated with depression in terms of defensive variables. For risk variables, anxiety (ES=.66), stress (ES=.53) showed high correlation effect size among the risk variables. Conclusion: These findings showed that defensive and risk variables were related to depression among stroke patients. Psychological interventions and improvement in physical functions should be effective in decreasing depression among stroke patients.

• 동력기계공학회지
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• 제14권1호
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• pp.59-64
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• 2010

Ferritic stainless steel is currently increasingly used for automotive exhaust material. The material for exhaust manifold is used in the temperature range of 500∼$850^{\circ}C$. Therefore, high temperature characteristic is an important one that affects it's life span. It has been investigated the effect of alloying elements of Cr, Mo, Nb, Ti in the ferritic stainless steel for exhaust manifold on the high temperature tensile strength. There was a few difference in the tensile strength at $600^{\circ}C$ with the exception of low Cr steel, but the steels containing higher Cr, Mo or Nb elements showed significantly higher tensile strength at the temperature of $800^{\circ}C$. The precipitates of the specimens after heat treating at the test temperature were electrolytic extracted, and quantitatively analysed using by SEM-EDS and TEM. The alloying elements of Cr and Mo increased the tensile strength as a solid solution strengthener, and on the other hand Nb element enhanced the strength by forming the fine intermetallic compounds such as NbC or $Fe_2Nb$.