• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2005년도 춘계종합학술대회
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• pp.750-753
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• 2005

우리 생활의 한 부분으로 자리하고 있는 인터넷 서비스는 생활환경의 변화뿐만 아니라 사람들의 가치관의 변화를 요구하고 있다. 이러한 각 사회의 급속한 변화는 교육활동에서도 예외가 아니다. 교육방법, 교육에 대한 인식, 교육에 필요한 여러 가지 도구나 환경에 있어서 많은 변화를 가져왔고, 그 변화의 중요한 하나가 웹 기반 학습의 도입이라 할 수 있다. 이러한 웹 기반 학습을 통하여 교육의 질을 향상시키고 효과적인 교수-학습이 이루어지도록 하기 위하여 본 논문에서는 실업계 고등학교의 학교 교육에 머시닝센터 학습을 웹 기반 CNC(computerized Numerical Control)프로그램과 가공 학습을 적용함으로써 학생들에게 새로운 정보와 접촉할 수 있는 기회와 다양한 학습 자료를 제공하는 실험 연구를 통하여 학생들의 학업성취도 및 학습동기 향상에 미치는 영향을 연구하는 것을 목적으로 한다.

• Radiation Oncology Journal
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• 제34권2호
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• pp.135-144
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• 2016

Purpose: The purpose of this study was to evaluate the efficacy of art therapy to control fatigue in cancer patients during course of radiotherapy and its impact on quality of life (QoL). Materials and Methods: Fifty cancer patients receiving radiotherapy received weekly art therapy sessions using famous painting appreciation. Fatigue and QoL were assessed using the Brief Fatigue Inventory (BFI) Scale and the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) at baseline before starting radiotherapy, every week for 4 weeks during radiotherapy, and at the end of radiotherapy. Mean changes of scores over time were analyzed using a generalized linear mixed model. Results: Of the 50 patients, 34 (68%) participated in 4 sessions of art therapy. Generalized linear mixed models testing for the effect of time on mean score changes showed no significant changes in scores from baseline for the BFI and FACIT-F. The mean BFI score and FACIT-F total score changed from 3.1 to 2.7 and from 110.7 to 109.2, respectively. Art therapy based on the appreciation of famous paintings led to increases in self-esteem by increasing self-realization and forming social relationships. Conclusion: Fatigue and QoL in cancer patients with art therapy do not deteriorate during a period of radiotherapy. Despite the single-arm small number of participants and pilot design, this study provides a strong initial demonstration that art therapy of appreciation for famous painting is worthy of further study for fatigue and QoL improvement. Further, it can play an important role in routine practice in cancer patients during radiotherapy.

• Biomolecules & Therapeutics
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• 제25권3호
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• pp.259-265
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• 2017

This study aimed to investigate the analgesic effect of substance P (SP) in an animal model of neuropathic pain. An experimental model of neuropathic pain, the chronic constriction injury (CCI) model, was established using ICR mice. An intravenous (i.v.) injection of SP (1 nmole/kg) was administered to the mice to examine the analgesic effects of systemic SP on neuropathic pain. Behavioral testing and immunostaining was performed following treatment of the CCI model with SP. SP attenuated mechanical allodynia in a time-dependent manner, beginning at 1 h following administration, peaking at 1 day post-injection, and decaying by 3 days post-injection. The second injection of SP also increased the threshold of mechanical allodynia, with the effects peaking on day 1 and decaying by day 3. A reduction in phospho-ERK and glial fibrillary acidic protein (GFAP) accompanied the attenuation of mechanical allodynia. We have shown for the first time that i.v. administration of substance P attenuated mechanical allodynia in the maintenance phase of neuropathic pain using von Frey's test, and simultaneously reduced levels of phospho-ERK and GFAP, which are representative biochemical markers of neuropathic pain. Importantly, glial cells in the dorsal horn of the spinal cord (L4-L5) of SP-treated CCI mice, expressed the anti-inflammatory cytokine, IL-10, which was not seen in vehicle saline-treated mice. Thus, i.v. administration of substance P may be beneficial for improving the treatment of patients with neuropathic pain, since it decreases the activity of nociceptive factors and increases the expression of anti-nociceptive factors.

• 융합정보논문지
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• 제11권10호
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• pp.115-130
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• 2021

본 연구는 일과 생활의 균형(WLB)과 상사신뢰, 직장행복감, 조직몰입 간의 전체적인 구조적 관계를 연구하는 것이다. WLB와 상사신뢰는 직장행복감에 어떠한 영향을 미치며, 직장행복감은 조직몰입에 어떠한 영향을 미치는가 그리고 직장행복감의 매개효과를 연구하는 것이다. 대기업 및 중소기업에 근무하는 직장 재직자들을 대상으로 설문자료를 수집하였으며, 연구항목의 타당성과 신뢰성을 확인하고 경로분석 방식으로 연구가설을 검정하였다. 연구가설의 검정결과 WLB와 상사신뢰는 직장행복감에 정(+)의 영향을 미치며, 직장행복감은 조직몰입에 정(+)의 영향을 미친다. 또한 직장행복감은 WLB와 상사신뢰, 조직몰입 사이를 부분매개하는 것으로 나타났다. 가설검정 결과를 토대로 WLB와 상사신뢰의 수준이 높을수록 직장행복감은 높아지며, 직장행복감이 제고될수록 조직몰입의 수준 역시 높다는 것을 확인하였다. 이러한 연구결과를 토대로 우리나라 기업 구성원들의 직장행복감과 조직몰입을 달성하기 위한 방안을 제시하였다.

• 품질경영학회지
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• 제49권3호
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• pp.341-358
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• 2021

Purpose: After product development, a Reliability Demonstration Test(RDT) is performed to confirm that the target life has been achieved. In the RDT, there are cases where the test equipment cannot accommodate all samples. Therefore, this study considers a test method to most economically demonstrate the target life of the product at a certain confidence level when the sample size is larger than the capacity of the test equipment. Methods: If the sample size is larger than the capacity of the test equipment, test equipments may be added or the test time of individual samples may be increased. So the test method is designed to cover this situation with limited capacity. A zero-failure test method is applied as a test method to RDT. To minimize the cost, the test cost is defined and the cost function is obtained. Finally, we obtain the optimal test plan. Results: A zero-failure test method is designed when the sample size is larger than the capacity of the test equipment, and the expected total cost is derived. In addition, the process of calculating the appropriate sample size, test time, and number of test equipment is illustrated through an example, and the effects of model parameters to the optimal solutions are investigated numerically. Conclusion: In this paper, we study a zero-failure RDT with test equipment that has limited capacity. The expected total cost is derived and the optimal sample size, test time, and number of test equipment are determined to minimize the expected total cost. We also studied numerical examples and for further studies, we can relax some restrictions in the test model and optimize the test method.

• 한국기후변화학회지
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• 제5권3호
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• pp.189-197
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• 2014

Carbon footprint of apple was a sum of $CO_2$ emission in the step of manufacturing waste of agri-materials, and greenhouse gas emission during apple cultivation. Input amount of agri-materials was calculated on 2007 Income reference of Apple by Rural Development Administration. Emission factor of each agri- materials was based on domestic data and Ecoinvent data. $N_2O$ emission factor was based on 1996 IPCC guideline. Carbon dioxide was emitted 0.64 kg $CO_2$ to produce 1 kg apple fruit, and carbon dioxide was emitted 43.6% in the step of the manufacturing byproduct fertilizer, 1.3% in the step of the manufacturing single fertilizer, 4.7% in the step of the manufacturing composite fertilizer, 6.3% in the step of the manufacturing agri-chemicals, 14.6% in the step of the manufacturing fuel, 11.5% in the step of the fuel combustion, 17.7% of $N_2O$ emission by nitrogen application and 0.18% of disposal of agri-materials. It is needed for farmers to use fertilization recommendation based on soil testing (soil. rda.go.kr) because scientific fertilization is a major tools to reduce carbon dioxide of apple production. The fertilization recommendation could be also basic data in Measurable-ReporTablele-Verifiable (MRV) system for carbon footprint.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권1호
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• pp.63-71
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• 2019

Purpose: The aim of this study was to identify the minimally meaningful dosage of inulin leading to a prebiotic effect in Indonesian infants. Methods: In a randomized controlled double-blinded, parallel, 3-arm intervention study, 164 healthy formula-fed infants aged 3 to 5 months first obtained formula-A (without inulin) during a 4-week adaptation period. Subsequently, 142 subjects were subjected to a 4-week feeding period by administering either formula-A (no inulin), formula-B (0.2 g/100 mL inulin) or formula-C (0.4 g/100 mL inulin). The primary outcome parameter was %-bifidobacteria in faecal samples determined using quantitative polymerase chain reaction analyses. Secondary outcome parameters were faecal %-lactobacilli, pH and stool frequency, and consistency. Growth and tolerance/adverse effects were recorded as safety parameters. Results: Typical %-bifidobacteria and %-lactobacilli at the end of the adaptation period in the study population were 14% and 2%, respectively. For faecal pH, significant differences between formula groups A vs. C and A vs. B were found at the end of the intervention period. Testing for differences in faecal %-bifidobacteria and %-lactobacilli between groups was hampered by non-normal data set distributions; no statistically significant differences were obtained. Comparisons within groups revealed that only in formula group C, all the three relevant parameters exhibited a significant effect with an increase in faecal %-bifidobacteria and %-lactobacilli and a decrease in pH. Conclusion: A consistent prebiotic effect along with a decrease in pH and increase in %-bifidobacteria and %-lactobacilli was found only in the group administered 0.4 g inulin/100 mL.

• Mycobiology
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• 제47권2호
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• pp.230-241
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• 2019

The Great Sebkha of Oran is a closed depression located in northwestern of Algeria. Despite the ranking of this sebkha among the wetlands of global importance by Ramsar Convention in 2002, no studies on the fungal community in this area have been carried out. In our study, samples were collected from two different regions. The first region is characterized by halophilic vegetation and cereal crops and the second by a total absence of vegetation. The isolated strains were identified morphologically then by molecular analysis. The biotechnological interest of the strains was evaluated by testing their ability to grow at different concentration of NaCl and to produce extracellular enzymes (i.e., lipase, amylase, protease, and cellulase) on solid medium. The results showed that the soil of sebkha is alkaline, with the exception of the soil of cereal crops that is neutral, and extremely saline. In this work, the species Gymnoascus halophilus, Trichoderma gamsii, the two phytopathogenic fungi, Fusarium brachygibbosum and Penicillium allii, and the teleomorphic form of P. longicatenatum observed for the first time in this species, were isolated for the first time in Algeria. The halotolerance test revealed that the majority of the isolated are halotolerant. Wallemia sp. and two strains of G. halophilus are the only obligate halophilic strains. All strains are capable to secrete at least one of the four tested enzymes. The most interesting species presenting the highest enzymatic index were Aspergillus sp. strain A4, Chaetomium sp. strain H1, P. vinaceum, G. halophilus, Wallemia sp. and Ustilago cynodontis.

• 동의생리병리학회지
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• 제33권4호
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• pp.239-248
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• 2019

There are no published data on Gyeongokgo (GOK) safety or efficacy despite being commonly use. The Gyeongokgo (GOK) is commonly used in traditional Korean medicine to promote a health qi and blood, but their objective data was not sufficient in clinical field. To investigate the safety and efficacy of GOK with hematologic and serologic testing and the change of the quality of life in healthy individuals. Randomized, subject-assessor-blind, placebo-controlled, single-center pilot study Participants and Interventions 29 healthy volunteer subjects were randomly placed into the GOK group (n = 20) or placebo control group (n = 9) and instructed to take one treatment packet (GOK or placebo) twice daily for 4 weeks. Subjects were assessed using the Fatigue Severity Scale (FSS) and Short Form 36 Health Survey (SF-36) and underwent hematologic and serologic tests and body composition analysis. The FSS total score (p = 0.093) and SF-36 general health index (p = 0.002) were improved following treatment in the GOK group. Post-treatment thyroid-stimulating hormone levels were increased in the GOK group compared with pre-treatment levels (p = 0.0042). C-reactive protein levels decreased (p = 0.0256) in the GOK group compared with that the placebo group. In time-series tests, GOK did not affect post-prandial serum triglycerides, glucose, insulin, or C-peptide levels. Notably, elevations in serum fasting triglycerides at 2- (p = 0.0333) and 4-hours (p = 0.0414) post-prandial were lower than those in the placebo group. GOK reduced fatigue levels and did not significantly affect laboratory test results performed to measure safety, serum glucose, and lipid profiles. Post-meal triglyceride levels were effectively reduced with treatment.

• 한국추진공학회지
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• 제23권1호
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• pp.46-51
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• 2019

Intermittent CSR 측정법을 이용하여 NBR 오링의 노화 거동과 수명 예측에 관하여 연구하였다. Intermittent CSR jig는 오링의 실제 사용 환경을 고려하여 설계 제작하였다. 오링의 노화 거동은 $40{\sim}120^{\circ}C$에서의 가속 노화 연구를 통하여 관찰하였다. 오링은 $80^{\circ}C$ 이하에서 비선형 노화 거동을 나타내었다. 오링의 수명은 고장 조건 20%에 대하여 Arrhenius plot으로부터 32.5년, WLF plot으로 부터 22.6년으로 나타났다.