Intravenous Administration of Substance P Attenuates Mechanical Allodynia Following Nerve Injury by Regulating Neuropathic Pain-Related Factors |
Chung, Eunkyung
(BIO R&D Center, L&K BIOMED CO., LTD.)
Yoon, Tae Gyoon (Department of Anesthesiology and Pain Medicine, Konkuk University Medical Center, Research Institute of Medical Science, Konkuk University School of Medicine) Kim, Sumin (Department of Genetic Engineering, College of Life Science and Graduate School of Biotechnology, Kyung Hee University) Kang, Moonkyu (Department of Dental Anesthesiology and Dental Research Institute, School of Dentistry, Seoul National University) Kim, Hyun Jeong (Department of Dental Anesthesiology and Dental Research Institute, School of Dentistry, Seoul National University) Son, Youngsook (Department of Genetic Engineering, College of Life Science and Graduate School of Biotechnology, Kyung Hee University) |
1 | Austin, P. J. and Moalem-Taylor, G. (2010) The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines. J. Neuroimmunol. 229, 26-50. DOI |
2 | Bradesi, S. (2010) Role of spinal cord glia in the central processing of peripheral pain perception. Neurogastroenterol. Motil. 22, 499-511. DOI |
3 | Chen, W. L., Zhang, Y. Q. and Zhao, Z. Q. (2006) Neurokinin-1 receptor in peripheral nerve terminals mediates thermal hyperalgesia. Biochem. Biophys. Res. Commun. 339, 132-136. DOI |
4 | Dong, X. G. and Yu, L. C. (2005) Alterations in the substance P-induced anti-nociception in the central nervous system of rats after morphine tolerance. Neurosci. Lett. 381, 47-50. DOI |
5 | Gao, Y. J., Zhang, Y. Q. and Zhao, J. Q. (2003) Involvement of spinal neurokinin-1 receptors in the maintenance but not induction of carrageenan-induced thermal hyperalgesia in the rat. Brain Res. Bull. 61, 587-593. DOI |
6 | Gao, Y. J. and Ji, R. R. (2010) Targeting astrocyte signaling for chronic pain. Neurotherapeutics 7, 482-493. DOI |
7 | Muto, Y., Sakai, A., Sakamoto, A. and Suzuki, H. (2012) Activation of NK1 receptors in the locus coeruleus induces analgesia through noradrenergic-mediated descending inhibition in a rat model of neuropathic pain. Br. J. Pharmacol. 166, 1047-1057. DOI |
8 | Nakayama, T., Naono, R., Ikeda, T. and Nishimori, T. (2010) NMDA and AMPA receptors contribute to the maintenance of substance P-induced thermal hyperalgesia. Neurosci. Res. 67, 18-24. DOI |
9 | Nichols, M. L., Allen, B. J., Rogers, S. D., Ghilardi, J. R., Honore, P., Luger, N. M., Pinke, M. P., Li, J., Lappi, D. A., Simone, D. A. and Mantyh, P. W. (1999) Transmission of chronic nociception by spinal neurons expressing the substance P receptor. Science 286, 1558-1561. DOI |
10 | Pailleux, F., Lemoine, J. and Beaudry, F. (2013) Investigation of the metabolic biotransformation of substance P in liver microsomes by liquid chromatography quadrupole ion trap mass spectrometry. Biomed. Chromatogr. 27, 39-47. DOI |
11 | Parenti, C., Arico, G., Ronsisvalle, G. and Scoto, G. M. (2012) Supraspinal injection of Substance P attenuates allodynia and hyperalgesia in a rat model of inflammatory pain. Peptides 34, 412-418. DOI |
12 | Parris, W. C. V., Kambam, J. R., Naukam, R. J. and Rama Sastry, B. V. (1990) Immunoreactive substance P is decreased in saliva of patients with chronic back pain syndromes. Anesth. Analg. 70, 63-67. DOI |
13 | Sahbaie, P., Shi, X., Guo, T. Z., Qiao, Y., Yeomans, D. C., Kingery, W. S. and Clark, J. D. (2009) Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision. Pain 145, 341-349. DOI |
14 | Shibata, K., Sugawara, T., Fujishita, K., Shinozaki, Y., Matsukawa, T., Suzuki, T. and Koizumi, S. (2011) The astrocyte-targeted therapy by Bushi for the neuropathic pain in mice. PLoS ONE 6, e23510. DOI |
15 | Takeda, K., Sawamura, S., Sekiyama, H., Tamai, H. and Hanaoka, K. (2004) Effect of methylprednisolone on neuropathic pain and spinal glial activation in rats. Anesthesiology 100, 1249-1257. DOI |
16 | Holden, J. E., Pizzi, J. A. and Jeong, Y. (2009) An NK1 receptor antagonist microinjected into the periaqueductal gray blocks lateral hypothalamic-induced antinociception in rats. Neurosci. Lett. 453, 115-119. DOI |
17 | Hong, H. S., Lee, J., Lee, E., Kwon, Y. S., Lee, E., Ahn, W., Jiang, M. H., Kim, J. C. and Son, Y. (2009) A new role of substance P as an injury-inducible messenger for mobilization of stromal-like cells. Nat. Med. 15, 425-435. DOI |
18 | Ji, F. T., Liang, J. J., Liu, L., Cao, M. H. and Li, F. (2013) Curcumin exerts antinociceptive effects by inhibiting the activation of astrocytes in spinal dorsal horn and the intracellular extracellular signal-regulated kinase signaling pathway in rat model of chronic constriction injury. Chin. Med. J 126, 1125-1131. |
19 | Jiang, M. H., Chung, E., Chi, G. F., Ahn, W., Lim, J. E., Hong, H. S., Kim, D. W., Choi, H., Kim, J. and Son, Y. (2012) Substance P induces M2-type macrophages after spinal cord injury. Neuroreport 23, 786-792. DOI |
20 | Shimizu, K., Guo, W., Wang, H., Zou, S., LaGraize, S. C., Iwata, K., Wei, F., Dubner, R. and Ren, K. (2009) Differential involvement of trigeminal transition zone and laminated subnucleus caudalis in orofacial deep and cutaneous hyperalgesia: the effects of interleukin-10 and glial inhibitors. Mol. Pain 5, 75. |
21 | Traub, R. J. (1996) The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat. Pain 67, 151-161. DOI |
22 | Vissers, K. C., Geenen, F., Biermans, R. and Meert, T. F. (2006) Pharmacological correlation between the formalin test and the neuropathic pain behavior in different species with chronic constriction injury. Pharmacol. Biochem. Behav. 84, 479-486. DOI |
23 | Wang, L. H., Zhou, S. X., Li, R. C., Zheng, L. R., Zhu, J. H., Hu, S. J. and Sun, Y. L. (2012) Serum levels of calcitonin gene-related peptide and substance P are decreased in patients with diabetes mellitus and coronary artery disease. J. Int. Med. Res. 40, 134-140. DOI |
24 | Komatsu, T., Sasaki, M., Sanai, K., Kuwahata, H., Sakurada, C., Tsuzuki, M., Iwata, Y., Sakurada, S. and Sakurada, T. (2009) Intrathecal substance P auguments morphine-induced antinociception: possible relevance in the production of substance P N-terminal fragments. Peptides 30, 1689-1696. DOI |
25 | Jiang, M. H., Lim, J. E., Chi, G. F., Ahn, W., Zhang, M., Chung, E. and Son Y. (2013) Substance P reduces apoptotic cell death possibly by modulating the immune response at the early stage after spinal cord injury. Neuroreport 24, 846-851. DOI |
26 | Kanai, Y., Nakazato, E., Fujiuchi, A., Hara, T. and Imai, A. (2005) Involvement of an increased spinal TRPV1 sensitization through its up-regulation in mechanical allodynia of CCI rats. Neuropharmacology 49, 977-984. DOI |
27 | Kim, K. J., Yoon, Y. W. and Chung, J. M. (1997) Comparison of three rodent neuropathic pain models. Exp. Brain Res. 113, 200-206. DOI |
28 | Komatsu, T., Mizoguchi, H., Sasaki, M., Sakurada, C., Tsuzuki, M., Sakurada, S. and Sakurada, T. (2011) Inhibition of ERK phosphorylation by substance P N-terminal fragment decreases capsaicin-induced nociceptive response. Neuropharmacology 61, 608-613. DOI |
29 | Ledeboer, A., Jekich, B. M., Sloane, E. M., Mahoney, J. H., Langer, S. J., Milligan, E. D., Martin, D., Maier, S. F., Johnson, K. W., Leinwand, L. A., Chavez, R. A. and Watkins, L. R. (2007) Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav. Immun. 21, 686-698. DOI |
30 | Lee, J. Y., Shin, T. J., Choi, J. M., Seo, K. S., Kim, H. J., Yoon, T. G., Lee, Y. S., Han, H., Chung, H. J., Oh, Y., Jung, S. J. and Shin, K. J. (2013) Antinociceptive curcuminoid, KMS4034, effects on inflammatory and neuropathic pain likely via modulating TRPV1 in mice. Br. J. Anaesth. 111, 667-672. DOI |
31 | Lee, M. J., Shin, T. J., Lee, J. E., Choo, H., Koh, H. Y., Chung, H. J., Pae, A. N., Lee, S. C. and Kim, H. J. (2010) KST5468, a new T-type calcium channel antagonist, has an antinociceptive effect on inflammatory and neuropathic pain models. Pharmacol. Biochem. Behav. 97, 198-204. DOI |
32 | Lee, W. H., Shin, T. J., Kim, H. J., Lee, J. K., Suh, H. W., Lee, S. C. and Seo, K. (2011) Intrathecal administration of botulinum neurotoxin type A attenuates formalin-induced nociceptive responses in mice. Anesth. Analg. 112, 228-235. DOI |
33 | Li, W. W., Guo, T. Z., Liang, D. Y., Sun, Y., Kingery, W. S. and Clark J. D. (2012) Substance P signaling controls mast cell activation, degranulation, and nociceptive sensitization in a rat fracture model of complex regional pain syndrome. Anesthesiology 116, 882-895. DOI |
34 | Lin, C. C., Chen, W. N., Chen, C. J., Lin, Y. W., Zimmer, A. and Chen, C. C. (2012) An antinociceptive role for substance P in acid-induced chronic muscle pain. Proc. Natl. Acad. Sci. U.S.A. 109, E76-E83. DOI |
35 | Ma, W. and Quirion, R. (2005) The ERK/MAP pathway, as a target for the treatment of neuropathic pain. Expert Opin. Ther. Targets 9, 699-713. DOI |
36 | Mika, J., Zychowska, M., Popiolek-Barczyk, K., Rojewska, E. and Przewlocka, B. (2013) Importance of glial activation in neuropathic pain. Eur. J. Pharmacol. 716, 106-119. DOI |
37 | Milligan, E. D. and Watkins, L. R. (2009) Pathological and protective roles of glia in chronic pain. Nat. Rev. Neurosci. 10, 23-36. DOI |
38 | Andoh, T., Nagasawa, T., Satoh, M. and Kuraishi, Y. (1998) Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice. J. Pharmacol. Exp. Ther. 286, 1140-1145. |