• 동력기계공학회지
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• 제10권4호
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• pp.127-132
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• 2006

Pneumatic cylinders that are usually applied in the factory automation line have complicated failure cause because they are composed of various elements. In this study, we performed life test and performance test of double acting pneumatic cylinders according to the international standards and then analyzed the life and the main failure mode of the cylinders in the same load condition. On the basis of these processes, we can estimate shape parameter for the reliability estimation of pneumatic cylinders and their data analysis of life distribution.

• BMB Reports
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• 제54권5호
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• pp.246-252
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• 2021

The Golgi complex plays a central role in protein secretion by regulating cargo sorting and trafficking. As these processes are of functional importance to cell polarity, motility, growth, and division, there is considerable interest in achieving a comprehensive understanding of Golgi complex biology. However, the unique stack structure of this organelle has been a major hurdle to our understanding of how proteins are secreted through the Golgi apparatus. Herein, we summarize available relevant research to gain an understanding of protein secretion via the Golgi complex. This includes the molecular mechanisms of intra-Golgi trafficking and cargo export in the trans-Golgi network. Moreover, we review recent insights on signaling pathways regulated by the Golgi complex and their physiological significance.

• 스마트미디어저널
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• 제11권11호
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• pp.63-74
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• 2022

Nowadays, lithium-ion battery has become more popular around the world. Knowing when batteries reach their end of life (EOL) is crucial. Accurately predicting the remaining useful life (RUL) of lithium-ion batteries is needed for battery health management systems and to avoid unexpected accidents. It gives information about the battery status and when we should replace the battery. With the rapid growth of machine learning and deep learning, data-driven approaches are proposed to address this problem. Extracting aging information from battery charge/discharge records, including voltage, current, and temperature, can determine the battery state and predict battery RUL. In this work, we first outlined the charging and discharging processes of lithium-ion batteries. We then summarize the proposed techniques and achievements in all published data-driven RUL prediction studies. From that, we give a discussion about the accomplishments and remaining works with the corresponding challenges in order to provide a direction for further research in this area.

• 기술사
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• 제34권3호
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• pp.10-15
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• 2001

The biotechnology is the study of biochemical and biological processes in living things. Since 1990's biotechnology has developed more repidly than all of the life technical industries, through the use of extremly sensitive analytical instruments, computers, and radioactive tracers. The biotechnician has been able to gain an understanding of the mechanisms and information on biotechnology, enables the biologist and biochemist to fine farther information about DNA techniques and human beings.

• 한국응급구조학회지
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• 제15권3호
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• pp.5-17
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• 2011

purpose : The purpose of this study was to analyze the effect of basic life support performance by video simulation training. Methods : The subjects in this study consisted of 24 persons of experimental group and 24 persons of control group in freshmen and sophomore EMT students. The data were collected from September 1 to 30, 2010. Results : 1. Hypothesis one: experimental group is meaningful higher than control group at the operation point (p<0.05) of adult/infant's basic life support for one person. In subcategory that identifying breath, artificial respiration, pulse rate, 30 compressions, Ability to perform all the processes, the experimental group showed statistically higher score (p<0.05) than control group, and sequence from checking reaction to keeping airway management isn't statistically significant difference between experimental group and control. 2. Hypothesis two: In the hypothesis, the experimental group's point of adult basic life support by two persons and use of Automated External Defibrillator is good in experimental group than control group's point(p<0.05). As the result of researching 11 contents of check list about adult basic life support by two persons and Automated External Defibrillator(AED), by dividing into 7 subcategories, every subcategory shows that the experimental group is significant higher than control group(p<0.05). 3. Hypothesis three: In the hypothesis, the experimental group gets higher point of infant basic life support by one or two persons than the control group (p<0.05). As the results of researching 15 contents of check list about infant basic life support by one or two persons, by dividing into 8 subcategories, the experimental group is statistically meaningful higher (p<0.05) than the control group in process of keeping airway, indentifying breathing, identifying pulse, 30 compressions, Ability to perform all the processes. There isn't statistically significant difference between the groups in process of checking reaction, reporting 119, and artificial respiration by giving 2 breaths(p<0.05). Conclusion : As summarizing the results, the group, receiving using video, gets higher points of knowledge of basic life support and operating skill than the general educated group. It is found that the Video simulation training could be effective, because of these positive effects to improve clinical working performance of students, who participate in the department of Emergency Medical Technology.

• Journal of Veterinary Science
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• 제23권6호
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• pp.90.01-90.13
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• 2022

Background: Insulin regulates glucose homeostasis and has important effects on metabolism, cell growth, and differentiation. Depending on the cell type and physiological context, insulin signal has specific pathways and biological outcomes in different tissues and cells. For studying the signal pathway of insulin on glycolipid metabolism in porcine embryonic fibroblast (PEF), we used high-throughput sequencing to monitor gene expression patterns regulated by insulin. Objectives: The goal of our research was to see how insulin affected glucose and lipid metabolism in PEFs. Methods: We cultured the PEFs with the addition of insulin and sampled them at 0, 48, and 72 h for RNA-Seq analysis in triplicate for each time point. Results: At 48 and 72 h, 801 and 1,176 genes were differentially expressed, respectively. Of these, 272 up-regulated genes and 264 down-regulated genes were common to both time points. Gene Ontology analysis was used to annotate the functions of the differentially expressed genes (DEGs), the biological processes related to lipid metabolism and cell cycle were dominant. And the DEGs were significantly enriched in interleukin-17 signaling pathway, phosphatidylinositol-3-kinase-protein kinase B signaling pathway, pyruvate metabolism, and others pathways related to lipid metabolism by Kyoto Encyclopedia of Genes and Genomes enrichment analysis. Conclusions: These results elucidate the transcriptomic response to insulin in PEF. The genes and pathways involved in the transcriptome mechanisms provide useful information for further research into the complicated molecular processes of insulin in PEF.

• 대한간호학회지
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• 제39권3호
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• pp.338-348
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• 2009

Purpose: The purpose of this study was to explore and describe healing effects of the forest on alcoholics through a forest experience program. Methods: The qualitative data was gathered from one focus group discussion with 6 alcoholics and individual interviews with 8 alcoholics. They had all participated in a "healing forest" program. All interviews were recorded and transcribed according to thematic content analysis processes. Results: The four main themes on the attributes of forest were "a lively living being", "placidity and tranquility", "acceptive atmosphere", and "beautifulness as it is" which revealed the participants' perceived nature of the forest which was attributed to the healing effects. Eight other themes on participants' positive changes included "revived senses", "aspired to live", "relieved and relaxed from being tense", "gaining insight on self", "having an acceptive attitude", "becoming compliant with his/her life", "learning that life is being together" and "recognizing the value of one's existence". Conclusion: The findings of the study illustrated the participants' self-healing processes through interactions with the nature of the forest. Nursing interventions utilizing healing atmospheres such as "healing forest" programs can be considered helpful in providing a venue to alcoholics to reflect on their lives affirmatively.

• Journal of Ecology and Environment
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• 제30권4호
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• pp.347-356
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• 2007

The structure and dynamics of Korean red pine stands established in the riparian zone were studied in the Tsang stream in Mt. Seorak National Park, in east-central Korea. Pine stands were classified into four successional stages, the initial, establishing, competitive, and stabilizing stages, based on the age distribution of a dominant tree, Pinus densiflora, the vegetation stratification, and the microtopography of the riverine environment. The stages usually corresponded to disturbance frequencies, depending on the horizontal and vertical distances from the watercourse. Stands of the initial and establishing stages lacked tree or subtree layers, or both. As stands progressed through the developmental stages, soil particle size became finer and moisture retention capacity was improved. The stand ordination reflected the developmental stage, and the species ordination differentiated species specializing in relatively dry and wet habitats. The results of the analysis of vegetation dynamics provided ecological information which will be useful for understanding the developmental processes of vegetation established in riparian zones. Species diversity indices usually increased across developmental stages, following the typical pattern for successional processes. We discuss the importance and necessity of riparian vegetation in Korea, where most riparian forests have disappeared due to excessive human land use.

• Environmental Engineering Research
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• 제22권4호
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• pp.363-368
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• 2017

The external diseconomy is hampering sustainable development of the city logistics sector. Burdens on urban environment imposed by the city logistics industry have been put in the spotlight. Based on the principle of Life Cycle Analysis, the comprehensive environment impact for city logistics systems is measured. Firstly, with the city logistics service chain as a whole, its business processes and their interactions with environment are analyzed. In total four types of major environment impact categories are determined. Secondly, case study is made on three city logistics operators located in Jing-Jin-Ji region of China with different business modes, respectively self-operation mode, joint distribution mode and the $3^{rd}$ Party Logistics or 3PL mode. Through analysis of energy consumption and emissions for various business processes, their comprehensive environmental impact values are finally obtained. Thirdly, horizontally comparative analysis is carried out to these three modes of the urban logistics distribution systems. Results show the advantages of the 3PL and the joint distribution modes in developing greener urban logistics distribution. Future research avenues and policy suggestions are proposed finally.

• Journal of Microbiology
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• 제39권3호
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• pp.149-153
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• 2001

The electron transfer reaction is one of the most essential processes of life. Not only does it provide the means of transforming solar and chemical energy into a utilizable form for all living organisms, it also extends into a range of metabolic processes that support the life of a cell. Thus, it is of great interest to understand the physical basis of the rates and reduction potentials of these reactions. To identify the major determinants of reduction potentials in redox proteins, we have chosen the simplest electron transfer protein, rubredoxin, a small (52-54 residue) iron-sulfur protein family, widely distributed in bacteria and archaea. Rubredoxins can be grouped into two classes based on the correlation of their reduction potentials with the identity of residue 44; those with Ala44 (ex: Pyrococcus furiosus) have reduction potentials that are ∼50 mV higher than those with Va144 (ex: Clostridium pasteurianum). Based on the crystal structures of rubredoxins from C. pasteurianum and P. furiosus, we propose the identity of residue 44 alone determines the reduction potential by the orientation of the electric dipole moment of the peptide bond between 43 and 44. Based on 1.5 $\AA$ resolution crystal structures and molecular dynamics simulations of oxidized and reduced rubredoxins from C. pasteurianum, the structural rearrangements upon reduction suggest specific mechanisms by which electron transfer reactions of rubredoxin should be facilitated.