• Asian Oncology Nursing
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• v.11 no.2
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• pp.127-135
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• 2011

Purpose: This study was performed to analyze the characteristics and effect sizes of intervention studies on foot-reflexo-massage applied to cancer patients. Methods: For meta-analysis, a total of 159 studies were retrieved from search engines such as RISS, nanet, KISS, richis and KoreaMed. 16 studies published from 1990 to 2010 were selected based on the inclusion criteria. The data were analyzed with the RevMan 5.0 program of Cochrane library. Results: 1) The mean score of 1 implement time on foot-reflexo-massage was 25.62 minutes, the average number of days was 4.12 days, and the total number of average intervention frequency was 4.25 times. 2) Intervention studies on foot-reflexo-massage included 9 studies on anxiety (56.3%), 7 for pain (43.8%), 5 for BP/pulse (31.3%), 5 for fatigue (31.3%), 3 for nausea/vomiting (18.8%), 3 for sleep satisfaction (18.8%), and 2 for depression (12.5%). 3) The effect sizes of the intervention studies that showed higher effect size were in order, anxiety (d=-1.76), fatigue (d=-1.43), depression (d=-1.03), nausea and vomiting (d=-0.83), pain (d=-0.77), pulse rate (d=-0.61), blood pressure (d=-0.55), and sleep satisfaction (d=0.43). Conclusion: This study suggests that foot-reflexo-massage can increase sleep satisfaction, whereas decreasing blood pressure, pulse rate, anxiety, fatigue, depression, nausea, vomiting and pain.

• Research in Community and Public Health Nursing
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• v.33 no.3
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• pp.340-355
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• 2022

Purpose: This study aimed to examine the effects of non-pharmacological sleep intervention programs in improving sleep quality among older adults in long-term care facilities. Methods: A literature search and selection was performed on nine different databases using the guidelines of PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). Overall, 14 studies met the inclusion criteria and were systematically reviewed. For the meta-analysis, the effect size was estimated using the random-effects model in Review Manager (RevMan) desktop version 5.4 of the Cochrane Library. Results: The meta-analysis of overall non-pharmacological interventions obtained a total effect size of 1.0 (standardized mean difference [SMD]=1.0, 95% confidence interval [CI]: 0.64~1.35), which was statistically significant (Z=5.55, p<.001). The most frequently studied non-pharmacological intervention was aroma therapy, with an effect size of 0.61 (SMD=0.61, 95% CI: 0.14~1.08), which was statistically significant (Z=2.55, p=.010). In the subgroup analysis, group-based interventions, interventions for >4 weeks, and untreated control studies were more effective. Conclusion: This study confirms that non-pharmacological interventions are effective in improving sleep quality among older adults in long-term care facilities. However, the sample size was small and the risk of bias in assessing the interventions of individual studies was unclear or high, thereby limiting the generalizability of the results. Further reviews that evaluate randomized control trials, evidence-based interventions that consider older adult participants' physical activity levels, different intervention methods and durations, and different control group intervention types are needed to obtain more conclusive evidence.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.4
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• pp.51-69
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• 2023

Objectives : The purpose of this study is to assess the effect of using Boyanghwano-tang(BYHWT) for diabetic retinopathy. Methods : We searched randomized controlled trials(RCTs) that used BYHWT for diabetic retinopathy in 10 databases(RISS, KISS, ScienceON, KCI, OASIS, DBpia, CNKI, Wanfang Database, PubMed, Cochrane Library) on August 12, 2023. Outcome measurements included total effective rate(TER) and visual acuity as the primary outcome measurements, and the secondary outcome measurements included fasting blood glucose(FBG), 2hPG, HbA1c, ET-1, NO, etc. The indicator of stability included adverse reactions. A meta-analysis was conducted according to TER, visual acuity, FBG. Results : A total of 8 randomized control trials were selected. The treatment group which used BYHWT showed significant improvement effects in TER and visual acuity compared to the control group which used western medicine or chinese patent medicine alone. TER: (RR: 1.22, CI 1.14 to 1.31, P=<0.00001), visual acuity: (RR: 2.06, CI 1.40 to 3.03, P=0.0002). Secondary outcome measurements including FBG also showed improvement in the treatment group compared to the control group. FBG: (MD: -0.15, CI -0.43 to 0.31, P=0.28). Adverse reactions were only mentioned in one study, which showed that no adverse reactions occurred in both the treatment and control groups. Conclusions : This study suggests that BYHWT is effective for diabetic retinopathy. However these findings should be interpreted cautiously due to the insufficient number of studies and unknown or high risk of bias in the included trials.

• Journal of Korean Library and Information Science Society
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• v.47 no.4
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• pp.489-510
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• 2016

It is defined in the internal standard of the NAK namely a NAK/G8-1:2013(v.1.) such as TIFF, PNG, PDF/A, JPEG 2000 as a Long-Term Preservation Master File for internal Standardization of Paper Archives in the Central Archives of Korea. This study reviewed the possibility that JPEG format could be a standard as a Long-Term Preservation Master File for internal Standardization of Paper Archives in the Central Archives of Korea. I pointed to the unique characteristics of JPEG file format and analysed and compared with TIFF format that is a representative master file. Through this study, I suggested that JPEG format also should be additionally included in the standard, as a master file, because it meets a qualification and functional requirements of master file and can guarantee the authenticity, reliability, integrity and usability. The meaning of this study is that JPEG format, be added to master file standard, can set up a environment that has lots of benefit in the domain of usability, compatibility to user as well as the authenticity, reliability, integrity.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.23 no.4
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• pp.93-108
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• 2012

The purpose of this study is to find any contradictions which arise with the use of Wiki in the classroom, and to address such contradictions in order to promote learning among LIS students. This study employed a multi-methodology, including Wiki usage analysis, and interviews with 12 students who participated in an LIS class. Observations revealed that group projects are common in academic classes. Interviewees agreed that their performance through collaborative efforts was higher than that through individually performed activities. However, there were no pre-experiences with Wiki in learning and task-oriented cooperation which gave rise to a controversy. In addition, even though a new technology, as a more advanced form, was suggested, students cooperated with their peers according to their tradition without using the recommended new technology. Therefore, students should be taught about Wiki usage and experience the effective learning which is available to them through collaboration with their peers. Additionally, LIS curriculum should incorporate relationship-oriented activities using Web 2.0 applications with the expectation of enhanced learning among students.

• Journal of Korean Library and Information Science Society
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• v.14
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• pp.39-69
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• 1987

The purpose of this research is to analyze the differences between literature (Belles-letters) class in DDC 19 and literature class in KDC 3. The results of the study can be summarized as follows : 1. The section of philosophy and theory of literature in DDC was subdivided according to the properties as including subsection of theory of criticism but KDC didn't subdivide this section. 2. In DDC, the subsections of 'rhetoric in specific languages' and 'rhetoric of specific kinds of composition' in rhetoric section was established and can subdivide according to each languages and subjects. These considerations can be useful as compared with KDC. 3. In DDC, collections or criticism of several literatures in specific forms can be more subdivide according to specific aspects or features dealing with in the collections or criticism by a n.0, pplying Table 3-A when specified more than the literary form. 4. Reviewing a notational rank to be assigned in literatures of specific languages, Latin literature and Classical Greek literature to be ranked in division in DDC was established as subsection in KDC to treat them as literatures of minor languages. 5. The DDC can sometimes a n.0, pply, in literatures of all languages, the notations of Table 3 to be subdivided again as specific kinds of literary forms, but KDC subdivided literary forms as specific kinds of each forms in only Korean, Chinese, Japanese literature. 6. In DDC, even literatures of minor languages are provided with 'the period table for the specific literature' under each literature of specific languages in schedules and these period tables can be a n.0, pplied a n.0, ppropriately, but period numbers in KDC was established in only Korean, Chinese, Japanese literature. 7. The optional use of letter prefixes or special numbers such as 828.99 to distinguish literatures of countries other than the "mother country" which makes the use of period tables feasible, but the KDC can only use to distinguish without the function of dividing a period such as DDC. 8. According to a n.0, pplying Table 3 and 3-A also in literatures of specific languages(810-890), a literature of specific languages, a specific literary form in literature of specific languages and a literature or literary form of specific period, in case of a n.0, pplying 'form divisions 08-09', can subdivide again by a specific aspect or feature dealing with in the works when specified. 9. For grasping the rate of subdividing, after selecting several sample-titles in literary field, they classified by DDC and KDC and gave a definite score in accordance with analytic small subjects. According to the results, the rate of subdividing in literature class of KDC is proved as less 22.8% than DDC. than DDC.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1803-1806
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• 2014

Endoscopic submucosal dissection (ESD) was originally developed for en bloc resection of large, flat gastrointestinal lesions. Compared with endoscopic mucosal resection (EMR), ESD is considered to be more time consuming and have more complications for treatment of early esophageal carcinoma, such as bleeding, stenosis and perforation. The objective of this study was to compare the efficacy and safety of ESD and EMR for such lesions. We searched databases, such as PubMed, EMBASE, Cochrane Library and Science Citation Index updated to 2013 for related trials. In the meta-analysis, the main outcome measurements were the en bloc resection rate, the histologically resection rate and the local recurrence rate. We also compared the operation time and the incidences of procedure-related complications. Five trials were identified, and a total of 710 patients and 795 lesions were included. The en bloc and histologically complete resection rates were higher in the ESD group compared with the EMR group (odds ratio (OR) 27.3; 95% CI, 11.5-64.8; OR 18.4; 95% CI, 8.82-38.59). The local recurrence rate was lower in the ESD group (OR 0.13, 95 % CI 0.04-0.43). The meta-analysis also showed ESD was more time consuming, but did not increase the complication rate (P=0.76). The results implied that compared with EMR, ESD showed better en bloc and histologically resection rates, and lower local recurrence, without increasing the incidence of procedure-related complications in the treatment of early esophageal carcinoma.

• Korean Journal of Clinical Pharmacy
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• v.28 no.4
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• pp.320-332
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• 2018

Background: This study was performed to clarify the effect of SLCO1B1 T521C on statin-induced myotoxicity. Methods: The PubMed, Embase, Ovid, and Cochrane Library databases were searched for all published studies between database inception and April 2018. Using Review Manager 5, the pooled odds ratio (OR) and corresponding 95% confidence interval (CI) were determined to assess the effect of SLCO1B1 T521C on statin-induced myotoxicity by using different genetic models. Results: Eleven observational studies and one randomized controlled trial were included in the meta-analysis. The pooled analysis showed that the incidence of statin-induced myotoxicity was significantly associated with the SLCO1B1 521C variant allele. Among patients using statins, the incidence of myotoxicity was higher in those carrying the 521TC or 521CC variant than in those carrying the 521TT variant in the dominant model (TC + CC vs TT, OR: 1.57; 95% CI: 1.20, 2.05; p = 0.001). The 521TC genotype was associated with a higher risk of myotoxicity than the 521TT genotype (OR: 1.42; 95% CI: 1.09, 1.86; p = 0.009). Furthermore, the incidence of myotoxicity was higher in 521CC carriers than in 521TC carriers (OR: 1.40; 95% CI: 1.06, 1.83; p = 0.02) and noticeably higher in 521CC carriers than in 521TT carriers (OR: 2.26; 95% CI: 1.23, 4.17; p = 0.009). Conclusion: The identification of individuals with the SLCO1B1 521C variant allele prior to the initiation of statin therapy might be useful to predict the risk of toxicity development, determine the individual dose, and prevent myotoxicity.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5343-5348
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• 2014

Background: A meta-analysis was performed to examine the benefit/risk ratio for the addition of anti- HER MoAbs to chemotherapy in patients with advanced gastric and gastroesophageal cancer from six randomized phase II/III trials. Materials and Methods: We searched relative trials from Pubmed, EMBASE, Cochrane library databases, China National Knowledge Infrastructure databases, Google Scholar and the NIH ClinicalTrials. Primary outcomes were overall response rate (ORR), progression-free survival (PFS), overall survival (OS). Secondary outcomes were toxicities. All analyses were performed using STATA 12.0. Results: This meta-analysis included six randomized controlled trials (RCTs) with 2, 297 patients and we demonstrated that the anti-HER MoAbs arm did have a positive effect on ORR in the anti-HER MoAbs arm (OR 1.28, 95% CI 1.00-1.64, p=0.01). There was an increasing benefit regarding OS (HR 0.74, 95% CI 0.60-0.88, p<0.05) and PFS (HR 0.72, 95% CI 0.60-0.84, p<0.05) in the anti-HER2 subgroup, but a reduction of OS (HR 1.11, 95% CI 0.87-1.36, p<0.05) and PFS (HR 1.13, 95% CI 0.98 -1.28, P<0.05) in anti-EGFR subgroup. Some grade 3-4 toxicity had a significantly higher incidence in the anti-HER MoAbs arm. There was no significant publication bias for all endpoints. Conclusions: The addition of trstuzumab MoAb to chemotherapy for gastric and gastroesophageal cancer significantly improved outcome of OS and PFS endpoints, while other MoAbs led to no improvement in results. Some adverse events were increased in anti-HER MoAbs arm compared with the control.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.3C
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• pp.102-111
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• 2005

In this paper, we propose an advanced hardware architecture for the fast inter prediction engine of the video coding standard MPEG-4 AVC. We describe the algorithm and derive the hardware architecture emphasizing and real time operation of the quarter_pel based motion estimation. The fast inter prediction engine is composed of block segmentation, motion estimation, motion compensation, and the fast quarter_pel calculator. The proposed architecture has been verified by ARM-interfaced emulation board using Excalibur & Virtex2 FPGA, and also by synthesis on Samsung 0.18 um CMOS technology. The synthesis result shows that the proposed hardware can operate at 62.5MHz. In this case, it can process about 88 QCIF video frames per second. The hardware is being used as a core module when implementing a complete MPEG-4 AVC video encoder chip for real-time multimedia application.