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Transition from Conventional to Reduced-Port Laparoscopic Gastrectomy to Treat Gastric Carcinoma: a Single Surgeon's Experience from a Small-Volume Center

  • Kim, Ho Goon;Kim, Dong Yi;Jeong, Oh
    • Journal of Gastric Cancer
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    • v.18 no.2
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    • pp.172-181
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    • 2018
  • Purpose: This study aimed to evaluate the surgical outcomes and investigate the feasibility of reduced-port laparoscopic gastrectomy using learning curve analysis in a small-volume center. Materials and Methods: We reviewed 269 patients who underwent laparoscopic distal gastrectomy (LDG) for gastric carcinoma between 2012 and 2017. Among them, 159 patients underwent reduced-port laparoscopic gastrectomy. The cumulative sum technique was used for quantitative assessment of the learning curve. Results: There were no statistically significant differences in the baseline characteristics of patients who underwent conventional and reduced-port LDG, and the operative time did not significantly differ between the groups. However, the amount of intraoperative bleeding was significantly lower in the reduced-port laparoscopic gastrectomy group (56.3 vs. 48.2 mL; P<0.001). There were no significant differences between the groups in terms of the first flatus time or length of hospital stay. Neither the incidence nor the severity of the complications significantly differed between the groups. The slope of the cumulative sum curve indicates the trend of learning performance. After 33 operations, the slope gently stabilized, which was regarded as the breakpoint of the learning curve. Conclusions: The surgical outcomes of reduced-port laparoscopic gastrectomy were comparable to those of conventional laparoscopic gastrectomy, suggesting that transition from conventional to reduced-port laparoscopic gastrectomy is feasible and safe, with a relatively short learning curve, in a small-volume center.

STUDY ON RADIOGRAPHIC EVALUATION OF MARGINAL BONE LOSS AROUND OSSEOINTEGRATED IMPLANT AFTER FUNCTIONAL LOADING (기능적 부하 후 임플란트 주변의 골 흡수에 대한 방사선학적 연구)

  • Choi, Su-Jin;Chee, Young-Deok;Koh, Se-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.35 no.4
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    • pp.240-247
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    • 2009
  • Purpose: The purpose of this study was to evaluate marginal bone loss to the bone crest functionally loaded for up to eighteen months and also with regard to other variables of interest. Material and Methods: 135 endosseous implants(GS II, Osstem, South Korea) were placed in 35 patients. The design of GS II implant is straight with the microthread. Radiographic examinations were conducted at baseline (implant loading) and 3, 6, 9, 12 and 18 months after loading. Marginal bone level measurement was made from the reference point to the lowest observed point of contact of the marginal bone with the fixture. The reference point of the fixture was the border between the blasted surface and machined surface of the fixture. Results: Implants were on function for a mean 12.7 months(range, 3?18 months). For the 56 maxillary and 79 mandibular implants, mean marginal bone loss was 0.68 mm and 0.70 mm. Implants placed maxillary posterior area displayed more crestal bone loss than the other position. The difference between mesial and distal bone levels was statistically significant (p<0.05) with respective means of 0.51 mm and 0.62 mm. Also, The difference between bone graft group and no-bone graft group was statistically significant(p<0.05) with respective means of 0.38 mm and 0.66 mm. But no statistically significant influence of sex, type of surgery(one or two stage surgery), the implant length was observed(p>0.05). Conclusion: This study indicates the amount of marginal bone loss around implant has maintained a relative stable during follow-up periods.

Optimum Design for Longitudinal Strength Members of Double Hull Tankers with Central Long'l Bulkhead considering Buckling Thickness Requirement of Plate Panels based on Common Structural Rules (CSR기반 좌굴 두께 요건을 고려한 이중선체유조선의 종방향 구조부재의 최적설계 연구)

  • Jo, Young-Chun;Lee, Jung-Chul;Lee, Sang-Bock;Shin, Sung-Kwang;Jang, Chang-Doo
    • Special Issue of the Society of Naval Architects of Korea
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    • 2011.09a
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    • pp.117-126
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    • 2011
  • The buckling assessment of plate panels described in common structural rules (CSR) is to be determined according to the buckling utilization factor with hull girder stresses calculated on net hull girder sectional properties. As the thickness requirement for the buckling assessment of plate panels is not explicitly given in CSR, a lot of time is spent to find the proper thickness of plate panels until reaching to an allowable buckling utilization factor. In this study, in order to reduce time and cost, the thickness requirement of plate panels satisfying buckling assessment was derived. The structural design system included with the thickness requirement for buckling assessment was developed. The system is called as Oil-tanker Automated Structural Investigation System (OASIS). The design result of longitudinal strength members using OASIS was verified by Nauticus Hull which is the rule scantling software of DNV. Finally, optimum design of a double hull tanker for the minimum weight using OASIS was presented.

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A Basic Study on the Air Circulation System for Heating using Solar and Geothermal Heat - Focused on Trombe Wall Thermal Storage Performance using Solar Heat - (태양열과 지열을 이용한 난방용 공기순환시스템 기초연구 - 태양열을 이용한 트롬월식의 축열성능 중심으로 -)

  • Kim, Byung-Yun;Choi, Yong-Seok
    • Journal of the Korean Institute of Rural Architecture
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    • v.19 no.4
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    • pp.49-56
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    • 2017
  • Each country in the world currently concentrates on shifting into clean energy, which can be alternative energy, for global environment protection and solution to the problem of fossil fuel depletion. The Korean government is predicted to develop renewable energy, such as solar power, ground power, and offshore wind power, and to increase their supply ratios by ending the use of coals and nuclear power plants. This study conducted experiments on thermal storage performance of Trombe wall thermal storage materials using solar power and simulations in order to offer baseline data for the development of a hybrid air circulation system for heating that can maximize efficiency by simultaneously using solar and geothermal power. The study results are as follows: (1) In all the specimens with 3m, 5m, and 7m in the length of thermal storage pipe, $5.7^{\circ}C$, $7.8^{\circ}C$, and $10.5^{\circ}C$ rose, respectively, as the thermal storage effect of the specimens attaching insulation film and black tape to the general funnel. They were most excellent in terms of thermal storage effect. (2) As a result of thermal performance evaluation on the II type specimens, II-3 ($7.8^{\circ}C$ rise) > II-4 ($5.3^{\circ}C$ rise) > II-1 ($3.9^{\circ}C$ rise) > II-2 ($2.3^{\circ}C$ rise) was revealed, and thus II-3 (insulation film + black tape) was most effective as shown in the I type. (3) This study analyzed air current and temperature distribution inside of the greenhouse by linking actually measured values and simulation interpretation results through the interpretation of CFD (computational fluid dynamics). As a result, the parts absorbing heat and discharging heat around the thermal storage pipe could be visibly classified, and temperature distribution inside of the greenhouse around the thermal storage pipe could be figured out.

Performance Enhancement Study Using Passive Control of Shock-Boundary Layer Interaction in a Transonic/Supersonic Compressor Cascade (천음속/초음속 압축기 익렬에서 Shock-Boundary Layer 상호작용의 수동적 제어에 의한 성능 향상 연구)

  • Kim, Sang-Deok;Gwon, Chang-O;Sa, Jong-Yeop
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.20 no.9
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    • pp.2944-2952
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    • 1996
  • In this paper the CSCM type upwind flux difference splitting Navier-Stokes method has been applied to study the ARL-SL19 transoni $c^ersonic compressor cascade flow. First, the general characteristics of baseline cascade flow were analyzed. At freestream Mach n.1.612 and exit/inlet pressure ratio 2.15, the results from current laminar flow were compared well in suction surface with the experiment; however, not well in pressure surface. Second, numerical study of the transoni $c^ersonic compressor cascade flow demonstrated the effectiveness of a passive control by the various size cavities. A cavity under the shock foot point at the suction surface of the blades was used as a passive control. The passive control of shock-boundary layer interaction by a cavity reduced total pressure losses. The effect of cavity length and depth was studied. The total pressure loss was reduced by about 10% and the isentropic efficiency was improved slightly. The effect of cavity depth in current study(d/l = 0.05, 0.02) was not found strong. Further adequate turbulence modeling and TVD schemes would help to capture the shock more accurately and increase the effectiveness of the current shock-boundary layer interaction study using upwind flux difference splitting computational methods.thods.

cDNA Cloning and Expression of a Cytochrome P450 1A (CYP1A) from the Pale Chub, Zacco platypus

  • Jeon, Hyoung-Joo;Park, Young-Chul;Lee, Wan-Ok;Lee, Jong-Ha;Kim, Jin-Hyoung
    • Korean Journal of Ecology and Environment
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    • v.44 no.4
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    • pp.364-372
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    • 2011
  • The pale chub (Zacco platypus) is generally found in Asian countries, such as Korea, Japan, and China. Nevertheless, very little information exists about the genes involved in the metabolism of xenobiotics in this species. This species is useful in monitoring the environmental impact on various pollutants in freshwater as a sentinel fish species. We cloned the full-length cDNA sequence of xenobiotic metabolizing cytochrome P450 1A (CYP1A) gene from Z. platypus and characterized it. Tissue distribution and timedependent induction of CYP1A were studied by real-time RT-PCR. Induction pattern of CYP1A was studied by exposing the fish to an arylhydrocarbon receptor agonist, ${\beta}$-naphthoflavone (BNF). The liver showed the highest level of expression in basal state as well as BNF- treated fish. However, appreciable levels of expression were also recorded in Gill and kidney and the least level of expression was observed in the eye. The results of the time-course study revealed an induction in the liver, brain, and gills after 6 h and 12 h in most of the tissues. This study provides an insight into the xenobiotics metabolizing system of Z. platypus and offers baseline information for further research related to biomarker, stress, and adaptive response of this ecologically important fish species in the freshwater environment.

Brain-Derived Neurotrophic Factor(BDNF) Genetic Polymorphism and the Long-term Outcome of Antidepressant Treatment in Korean Depressive Patients (한국인 우울 장애 환자에서 Brain-Derived Neurotrophic Factor(BDNF)의 유전자 다형성과 항우울제의 장기 치료 반응)

  • Koo, Jae-Woo;Lee, Hwa-Young;Paik, Jong-Woo;Kang, Rhee-Hun;Lee, Min-Soo
    • Korean Journal of Biological Psychiatry
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    • v.13 no.3
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    • pp.162-169
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    • 2006
  • Objective : Since some studies have shown that the brain-derived neurotrophic factor(BDNF) has an important role in the pathophysiology of depression, this study investigated the relationship between BDNF genetic polymorphism and the long-term outcome of the antidepressant treatment. Method : One hundred and eight patients with major depressive disorder were evaluated for the long-term outcome(up to 3 years) of antidepressant treatment. The severity and improvement of depression were assessed with the Clinical Global Impression(CGI) Scale. The genotypes of BDNF 196A/G polymorphism in the patients were determined using Restriction Fragment Length Polymorphism(RFLP). Result : The genotypes of 128 patients were investigated and 95 patients of those have been evaluated for 3 years. No significant differences were noted comparing three-genotype groups for CGI scales at baseline, 4 weeks, 8 weeks, 1 year, 2 years and 3 years. Conclusion : This result shows that BDNF polymorphism investigated in this study was not associated with the long-term outcome of the antidepressant treatment. However, further studies with another BDNF polymorphism should be needed.

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The Age and Spawning Characteristics of the Korean Endemic Spine Loach, Iksookimia pacifica (Pisces: Cobitidae) in the Bukcheon (stream), Korea (한국고유종 북방종개 Iksookimia pacifica (Pisces: Cobitidae)의 연령 및 산란기 특징)

  • Ko, Myeong-Hun;Won, Yong-Jin
    • Korean Journal of Ichthyology
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    • v.28 no.2
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    • pp.72-78
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    • 2016
  • The age and spawning characteristics of Iksookimia pacifica were investigated in this study to provide baseline data for its ecological characteristics in the Bukcheon (stream), Goseong-gun, Gangwon-do, Korea from January to December, 2013. Age groups of I. pacifica (female) estimated by the frequency distribution of total length in the spawning season indicated that the 30~49 mm group is 1 year old, the 50~74 mm group is 2 years old, the 75~99 mm group is 3 years old, the 100~124 mm group is 4 years old, and the 130~160 mm group is $5{\leq}$years old. The sex ratio (♂/♀) was 0.63, and females were 30~60 mm larger than males. The lamina circularis at the base of pectoral fins in males as a secondary sexual character was created at the 13th month after hatching. The spawning season according to the gonadosomatic index (GSI) was July to August (main spawning season in July) with water temperatures of $20{\sim}25^{\circ}C$. The average number of eggs was $2,503{\pm}1,337$ with a diameter of $1.11{\pm}0.04mm$ in mature eggs.

Evaluation of Reduced Port Laparoscopic Distal Gastrectomy Performed by a Novice Surgeon

  • Park, Dong Jin;Lee, Eun Ji;Kim, Gyu Youl
    • Journal of Gastric Cancer
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    • v.21 no.2
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    • pp.179-190
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    • 2021
  • Purpose: Reduced port laparoscopic distal gastrectomy (RPLDG) using 3 ports is less invasive than conventional laparoscopic distal gastrectomy (CLDG) using 5 ports. Although RPLDG performed by expert surgeons is safe and feasible, novice surgeons have difficulty performing this procedure. This study evaluated the surgical outcomes and feasibility of RPLDG performed by a novice surgeon. Materials and Methods: The records of 136 patients who underwent laparoscopic distal gastrectomy for gastric cancer performed by a single novice surgeon between May 2016 and December 2018 were retrospectively reviewed. Among these 136 patients, 52 underwent RPLDG and 84 underwent CLDG. The clinicopathological characteristics, operative outcomes, and short-term postoperative outcomes of the 2 groups were compared. Results: The percentage of women was significantly higher in the RPLDG group than in the CLDG group (48.1% vs. 31%; P=0.045), but other baseline characteristics did not differ significantly between the groups. Billroth II anastomosis was performed significantly more frequent (90.4% vs. 73.8%, P=0.015) and operation time was significantly shorter (207.1±43.3 min vs. 225.5±44.6 min, P=0.020) in the RPLDG group than in the CLDG group. The time to first flatus, postoperative pain score, length of postoperative hospital stay, and incidence and severity of complications did not differ significantly between the groups. Analysis of the learning curve based on the operation time showed that performing RPLDG on 20-30 patients was required to achieve technical proficiency. Conclusions: RPLDG is a safe and feasible surgical procedure for the treatment of gastric cancer, even when performed by a novice surgeon.

Effect of Non-invasive Transcutaneous Electrical Stimulation in Women With Stress Urinary Incontinence: A Prospective Study

  • Ji-hyun Kim;Hye-seon Jeon;Oh-yun Kwon;Ui-jae Hwang;Eun Young Park;Su-jin Kim
    • Physical Therapy Korea
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    • v.31 no.2
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    • pp.167-173
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    • 2024
  • Background: Stress urinary incontinence (SUI) impacts the social, physical, and psychological well-being and quality of life of the patient. Several techniques exist for its management, including transcutaneous electrical stimulation (TES). Objects: We aimed to demonstrate the effects of TES on ultrasonographic variables and quality of life in women with SUI. Methods: This prospective study recruited 21 women who had been diagnosed with grade 1 or 2 SUI between July 2018 and March 2019. The exclusion criteria were pregnancy and a history of urogenital surgery. All participants were assessed at baseline and 8 weeks after intervention initiation. The bladder neck position (BNP), length of the urethra (LU), funneling index (FI), and rhabdosphincter thickness (RT) were measured. The Incontinence-Quality of Life (I-QOL) was used to assess incontinence-specific quality of life. Statistical significance level was set at p < 0.05. Results: Twenty-one patients with SUI used TES for 8 weeks. BNP and FI significantly decreased after intervention (p < 0.05). LU, anterior and posterior RT (indicators of external sphincter hypertrophy) significantly increased post-intervention (p < 0.05). The total I-QOL score increased from 64.81 to 71.86 after the intervention (p < 0.05). Conclusion: This intervention improved BNP, LU, FI, RT, and subjective indicators such as quality of life in women with SUI. Therefore, TES can be an effective non-surgical treatment method for improving SUI symptoms and quality of life in these patients.