• Toxicological Research
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• v.24 no.2
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• pp.151-159
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• 2008

Rhus verniciflua Stokes(RVS), one of traditional medicinal plants in Asia, was found to have pharmacological activities such as antioxidative and antiapoptotic effects, raising the possibility for the development of a novel class of anti-cancer drugs. Thus, potential genotoxic effects of RVS in three short-term mutagenicity assays were investigated, which included the Ames assay, in vitro Chromosomal aberration test, and the in vivo Micronucleus assay. In Ames test, the addition of RVS water extracts at doses from 313 up to 5000 mg/plate induced an increase more than 2-fold over vehicle control in the number of revertant colonies in TA98 and TA1537 strains for detecting the frame-shift mutagens. The similar increase in reversion frequency was observed after the addition of RVS ethanol extracts. To assess clastogenic effect, in vitro chromosomal aberration test and in vivo micronucleus assay were performed using Chinese hamster lung cells and male ICR mice, respectively. Both water and ethanol extracts from RVS induced significant increases in the number of metaphases with structural aberrations mostly at concentrations showing the cell survival less than 60% as assessed by in vitro CA test. Also, there was a weak but statistically significant increase in number of micronucleated polychromatic erythrocytes(MNPCEs) in mice treated with water extract at 2000 mg/kg while ethanol extracts of RVS at doses of up to 2000 mg/kg did not induce any statistically significant changes in the incidence of MNPCEs. Therefore, our results lead to conclusion that RVS acts as a genotoxic material based on the available in vitro and in vivo results.

• Radiation Oncology Journal
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• v.7 no.1
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• pp.123-132
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• 1989

A radiation beam incident on an irregular or sloping surface produces the non-uniformity of absorded dose. The use of a tissue compensator can partially correct this dose inhomogeneity. The tissue compensator is designed based on the patient's three dimensional contour. After required compensator thickness was determined according to tissue deficit at $25cm\pm25cm$ field size, 10cm depth for 6MV x-rays, tissue deficit was mapped by isoheight technique using laser beam system. Compensator was constructed along the designed model using 0.8mm lead sheet or 5mm acryl plate. Dosimetric verification were peformed by film dosimetry using humanoid phantom. Dosimetric measurements were normalized to central axis full phantom readings for both compensated and non-compensated field. Without compensation, the percent differences in absorbed dose ranged as high as $12.1\%$ along transverse axis, $10.8\%$ along vertical axis. With the tissue compensators in place, the difference was reduced to $0\~43\%$ Therefore, it can be concluded that the compensator system constructed by isoheihnt technique can produce good dose distribution with acceptible inhomogeneity, and such compensator system can be effectively applied to clinical radiotherapy.

• Structural Engineering and Mechanics
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• v.65 no.4
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• pp.491-504
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• 2018

Because of sandwich structures with low weight and high stiffness have much usage in various industries such as civil and aerospace engineering, in this article, buckling and free vibration analyses of coupled micro composite sandwich plates are investigated based on sinusoidal shear deformation (SSDT) and most general strain gradient theories (MGSGT). It is assumed that the sandwich structure rested on an orthotropic elastic foundation and make of four composite face sheets with temperature-dependent material properties that they reinforced by carbon and boron nitride nanotubes and two flexible transversely orthotropic cores. Mathematical formulation is presented using Hamilton's principle and governing equations of motions are derived based on energy approach and applying variation method for simply supported edges under electro-magneto-thermo-mechanical, axial buckling and pre-stresses loadings. In order to predict the effects of various parameters such as material length scale parameter, length to width ratio, length to thickness ratio, thickness of face sheets to core thickness ratio, nanotubes volume fraction, pre-stress load and orthotropic elastic medium on the natural frequencies and critical buckling load of double-bonded micro composite sandwich plates. It is found that orthotropic elastic medium has a special role on the system stability and increasing Winkler and Pasternak constants lead to enhance the natural frequency and critical buckling load of micro plates, while decrease natural frequency and critical buckling load with increasing temperature changes. Also, it is showed that pre-stresses due to help the axial buckling load causes that delay the buckling phenomenon. Moreover, it is concluded that the sandwich structures with orthotropic cores have high stiffness, but because they are not economical, thus it is necessary the sandwich plates reinforce by carbon or boron nitride nanotubes specially, because these nanotubes have important thermal and mechanical properties in comparison of the other reinforcement.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.3 no.4
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• pp.73-80
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• 2004

A dual purpose robot automation system is developed for both arc welding and spot welding by one robot within a cell. The need for automation of both arc welding and spot welding processes is urgent while the production volume is not so big as to accommodate separate station for the two processes. Also, space is too narrow for separate station to be settled down in the factory. A spot welding robot is chosen and the function for arc welding are implemented in-house at cost of advanced functions. For the spot welding, a single pole type gun is used and the robot has to push down the plate to be welded, which causes the robot positioning error. Therefore, position error compensation algorithm is developed. The basic functions for the arc welding processes are implemented using the digital I/O board of robot controller, PLC, and A/D conversion PCB. The weaving pattern is taught in meticulously by manual teach. A fixture unit is also developed for dual purpose. The main aspects of the system is presented in this paper especially in the design and implementation procedure. The signal diagrams and sequence logic diagrams are also included. The outcome of the dual purpose welding cell is the increased productivity and good production stability which is indispensable for production volume prediction. Also, it leads to reduction of manufacturing lead time.

• Progress in Medical Physics
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• v.13 no.2
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• pp.62-68
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• 2002

A muiltileaf collimator (MLC) is used as a replacement for conventional blocks. The MLC, however may not be appropriate for a fine field shaping. For the fine field shaping, conventional block can be added under the MLC. But it may significantly affect on the dosimetric characteristics such as surface dose of skin, buildup region and percent depth doses. We performed the study to evaluate the surface dose and the maximum depth dose using MLC conjunction with conventional blocks for various field sizes and energies. We confirmed the surface dose was increased by using the additional conventional block under the MLC ranging from 10 to 35.6％ according to various field sizes and radiation beam energies. The surface dose was effectively reduced by application of 2 or 3 m thickness of lead plate as electron filter.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.2
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• pp.127-135
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• 2006

We analyzed recyclability of the fuel tanks made from steel or aluminum alloy. For a comparison of the fuel tank recyclability, first we had analyzed the process of disassembly in a vehicle and evaluated its disassemblability. Then we evaluated the recyclability for reuse and withdrawal. The processes were more or less same owing to the similarity of fastening method of fuel tank and components. However, the fuel tank of the aluminum alloy was easier (about 5%) to disassembly than the fuel tank of steel. This could be attributed to the differences in weight of steel and aluminium. On light of the withdrawal and reuse, the fuel tank made up of steel needed to plate with zinc or lead due to its anti-corrosiveness. Hence, it required additional processes. In this paper, we were explaining the results of our on going research on the recyclability of fuel tanks made of steel and aluminum alloys. The differences that we found between the fuel tank made up of the aluminum alloy and steel were in their weight, recyclability, disassemblability, anticorrosive property, cost and productivity.

• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.1
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• pp.67-73
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• 2017

This study has addressed to evaluate the effects of radius of curvature and skew angle on the negative reaction in a plate girder bridge with LRB (Lead Rubber Bearing) supports. As analytical parameters, various radius of curvatures and skew angles were selected and two seismic loads of El-Centro and artificial earthquakes were applied to the bridge in the longitudinal and transverse directions. As results of 3D analysis, the possibility of negative reaction is shown at the part of acute angle and inner side of the curved bridge, and becomes increased when seismic load is applied in the transverse direction. In addition, the occurrence of negative reaction is found to be increased as both radius of curvature and skew angle decrease, which means that curved bridge has higher possibility of negative reaction than straight one. Conclusively, all of earthquake wave, gradient, radius of curvature and skew angle should be considered together to investigate the possibility of negative reaction at the bridge support subject to seismic load.

• Journal of the Institute of Convergence Signal Processing
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• v.9 no.1
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• pp.10-17
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• 2008

The purpose of this thesis is to reduce of error for source location through acoustic emission(AE) signal, generated elastic wave from crack growth to leak for facility diagnosis. Especially, in order to overcome noise from original signal, this paper proposed enhancement of source location by using noise reduction based on wavelet transform. To evaluate actual performance in experiments, Pencil Lead Break is used crack signal source on the aluminum plate and drain valve of air compressor is used as substitute pressure vessel to generate leak signal. In signal processing, wavelet shrinkage and soft threshold are used to discriminate signal source and then source location techniques have been effectively used with group velocity using material property and time difference between sensor using cross correlation. Source location for crack and leak test have some difference, but the result show that improved 30% with a average length within 10.46mm in crack test and improved 2% compare with average filter in leak test when we applied wavelet transform.

• Journal of Environmental Health Sciences
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• v.19 no.1
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• pp.44-50
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• 1993

In order to investigate the hygienic conditions of potable water in farm area, we examined the hygienic bacteriological and chemical tests of the 159 waters in the farm areas of Kwangjugun, Namyangju-gun, Yangpyung-gun Paju-gun and Hwasung-gun.The results were as follows: 1. Of the 159 waters, the average numbers of standard plate count and coliform were 920 $\pm$ 250ml and 450 $\pm$ 380/100 ml, respectively. The average pH was 6.74 $\pm$ 0.08, KMnO$_4$ consumption 4.18 $\pm$ 0.23 mg/l, turbidity 0.74 $\pm$ 0.08 degree, NH$_3$-N 0.07 $\pm$ 0.02 mg/l, NO$_3$-N 7.76 $\pm$ 0.48 mg/l, total hardness 101.3 $\pm$ 4.7mg/l, chlorine 18.6 $\pm$ 1.3mg/l, sulfate 12.9 $\pm$ 1.0 mg/l, lead 0.036 $\pm$ 0.003 mg/l, manganese 0.017 $\pm$ 0.003 mg/l, zinc 0.064 $\pm$ 0.005 mg/l, and copper 0.010 $\pm$ 0.001 mg/l, respectively. 2. Of the 159 waters, 84 samples (52.8%) were over 100 per ml of SPC or detected coliform per 100 ml water and 63 samples (39.6%) exceed over physicochemical limited criteria for potable water. NO$_3$-N was the primary item among excess contents of potable water in farm areas. 3. The contents of total hardness, chlorine and NO$_3$-N in Hwasung-gun were higher than those in the other regions, but the numbers of SPC and coliform in Yangpyung-gun and Namyangjugun were higher than those in the other regions. 4. The correlationships among many items were highly significant (SPC, Coliform, KMnO$_4$ consumption NH$_4$-N, NO$_3$-N, KMnO$_4$, Total hardness, Chlorine, Sulfate).

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.41 no.1
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• pp.30-36
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• 2015

Objectives: The aim of this study is to determine the incidence, location, and orientation of maxillary sinus septa in formalin embalmed cadavers. Materials and Methods: The study was conducted on 210 cadaveric heads available in our department. After taking the mid-sagittal section the specimens were opened from the medial aspect and the sinus sinus septa, their anatomical plane, location and dimensions. Results: The mean linear distance between maxillary sinus floor and its anatomical ostium was $26.76{\pm}5.21mm$ and $26.91{\pm}4.96mm$ on right and left side, respectively. A total of 59 maxillary sinus septa (28.1%) were observed in 210 maxillary specimens. Septae were most common, 33 septa (55.9%), in the middle region (between first and second molar tooth) of the sinus cavity. The maxillary sinus membrane (Schneiderian membrane) adhered tightly to the maxillary sinus and over the septae. Significantly more maxillary sinus septa were observed in edentulous maxillae in comparison to the dentate upper jaw. Conclusion: Knowledge of location of maxillary sinus ostium is mandatory for the rhinologist for drainage of secretions in maxillary sinusitis. The morphological details of maxillary sinus septa, particularly their location and anatomical planes, will guide dentists in performance of safe implant surgeries. The maxillary antrum septa of category I and II may complicate the procedure of inversion of bone plate and elevation of sinus membrane during maxillary augmentation surgeries. The category III septa observed in the sagittal plane were embedded by one of the branches of the infraorbital nerve in it, and if accidentally cut will lead to infraorbital nerve palsy in maxillary sinus surgeries.