• 대한인간공학회지
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• 제13권2호
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• pp.43-48
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• 1994

Among many kinds of odors, some are known to have effects of sedation or stimulation on brain activity. In this study, brain activity levels affected by four kinds of fragrance0lemon, lavender, jasmine, and rose-were tested using EEG recording. In the first experiment, the quality of alpha wave was examined under controlled rest condition. In the second experiment, the event-related potential (ERP) and contingent negative variation (CNV) were investigated during a simple reaction tasks (SRT) against auditory signal. EEG data obtained for the rest condition were analyzed suing "3-Dimensional Viewer)" which was developed by ourselves to show the chaotic attractor of the signal. Power spectrum were also calculated using FET. EEG data obtained during the SRT were analyzed by comparing CNV amplitudes about each odor condition. Results confirmed the sedative effect of the lemon and the lavender, and the stimulative effect of the jasmine and the rose.

• 한국연초학회지
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• 제25권1호
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• pp.7-11
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• 2003

Repellencies of herb plants and essential oils against alate Myzus persicae were investigated in a insect cage, a screen house, and a tobacco field. Numbers of nymphs deposited by alate or apterous Myzur persicae were lower on rosemary(Rosmarinus officinalis), silver thyme (Thymus vulgaris), and lemon balm(Melissa of fcianazis). Rosemary and silver thyme show little repellency against alate Myzus persicae on a nearby tobacco plant Rosemary oil, peppermint (Mentha piperita) oil, and ginger oil showed repellency against alate Myzus persicae, but spearmint (Mentha spicata) oil and lavender oil showed little repellency in a screen house. Rosemary oil, ginger oil, peppermint oil, lavender oil, and spearmint oil showed repellency against alate Myzus persicae in a tobacco field, but there was no significant difference among oils.

• Toxicological Research
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• 제32권2호
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• pp.103-108
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• 2016

The purpose of this study was to determine the hair growth effects of lavender oil (LO) in female C57BL/6 mice. The experimental animals were divided into a normal group (N: saline), a vehicle control group (VC: jojoba oil), a positive control group (PC: 3% minoxidil), experimental group 1 (E1: 3% LO), and experimental group 2 (E2: 5% LO). Test compound solutions were topically applied to the backs of the mice ($100{\mu}L$ per application), once per day, 5 times a week, for 4 weeks. The changes in hair follicle number, dermal thickness, and hair follicle depth were observed in skin tissues stained with hematoxylin and eosin, and the number of mast cells was measured in the dermal and hypodermal layers stained with toluidine blue. PC, E1, and E2 groups showed a significantly increased number of hair follicles, deepened hair follicle depth, and thickened dermal layer, along with a significantly decreased number of mast cells compared to the N group. These results indicated that LO has a marked hair growth-promoting effect, as observed morphologically and histologically. There was no significant difference in the weight of the thymus among the groups. However, both absolute and relative weights of the spleen were significantly higher in the PC group than in the N, VC, E1, or E2 group at week 4. Thus, LO could be practically applied as a hair growth-promoting agent.

• 동서간호학연구지
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• 제18권2호
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• pp.66-73
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• 2012

Purpose: This study examines the effect of aroma inhalation therapy with lavender and rosewood essential oils for alleviating fatigue and enhancing quality of sleep in nurse shift workers. Methods: The data were collected from November 9th to 27th in 2009 at four hospitals located in Seoul. Total 60 nurses who started their night-shift works were chosen for the study and allocated to either experimental group or control group. The experimental group had had aroma inhalation therapy with lavender and rosewood for 2 weeks and was compared the level of fatigue and quality of sleep with those of the control group. Results: Significant differences were shown between the experimental group and the control group. After 2 weeks, the nurses in experimental group reported significantly lower level of fatigue and higher quality of sleep compared to the nurses in control group. Conclusion: Therefore, aroma inhalation therapy by using lavender and rosewood essential oils can be an effective intervention for relieving the level of fatigue and enhancing quality of sleepf for nurse shift workers.

• 생명과학회지
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• 제20권8호
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• pp.1230-1234
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• 2010

천연 허브에서 추출된 정유의 스트레스 완화능이 알려지면서 화장품, 식품 산업뿐 아니라 다양한 기능성 제품에 활용되고 있다. 본 연구에서는 정유 향 흡입의 스트레스 완화 효과에 대한 과학적인 근거를 마련하기 위하여 마우스의 구속 스트레스에 대한 3가지 정유의 흡입 효과를 비교 하였다. 마우스를 1시간 구속한 경우 혈청 코티졸 농도의 유의적인 상승, 체온의 저하 및 혈중 중성지질의 상승을 확인하였으며, 10% 라벤더 오일을 30분간 흡입 한 경우, 혈청 코티졸 농도 상승 및 체온 저하가 유의적으로 억제되어 스트레스 완화 효과가 가장 좋았다. 한편 혈중 중성지질의 증가 억제효과는 실버퍼 오일 흡입에서 유의적으로 감소하였다. 본 연구에서는 폭넓게 사용되는 정유를 이용하여 정유 향 흡입의 스트레스 완화 효과를 측정 함으로서 앞으로의 연구와 활용에 대한 기본적인 과학적 근거를 마련하였다.

• 한국식품영양학회지
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• 제21권3호
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• pp.312-319
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• 2008

The principal objective of was to assess the effects of herb extracts on the antioxidant activity and quality characteristics of Maejakgwa. The total phenolic and flavonoid contents were found to be the highest by a significant degree in the rosemary, lavender, thyme, lemon balm and olive samples, in order. With regard to electron donating ability, increasing concentrations of added herbs resulted in a more significant rise in the DPPH radical scavenging effect in a range of concentrations of between $100{\sim}1000{\mu}g/m{\ell}$. In particular, the rosemary, lavender, and thyme samples were shown to be lower in antioxidant activity than ascorbic acid, but higher than a-tocopherol, thus the antioxidant activities detected in the rosemary, lavender, and thyme samples were considered to be excellent. With regard to reducing ability, increases in the concentration of added herb extract resulted in significant growth. However, the anti-oxidative activity detected in the rosemary extract was indicated to be superior even to that of $\alpha$-tocopherol when added to concentrations of $500{\sim}1,000{\mu}g/m{\ell}$. In our assessment of external appearance, color, flavor, texture, and overall quality, the highest preference was seen in the control group and in the group with 2% added rosemary extract. The lowest score was earned in the group with a 5% addition of rosemary. The functional ingredients and antioxidant activities of the samples were excellent. Our results appear to indicate that rosemary has some value as a natural antioxidant that can prevent oxidation in food.

• 감성과학
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• 제5권2호
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• pp.1-9
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• 2002

향-냄새에 대한 감수성은 종족, 성에 따라 상이하며 냄새에 대한 인지력과 식별력은 가령화에 따라 쇠퇴한다고 한다. 가령화에 따른 향의 평가에 관한 선행보고들은 그 대상이 유아에서 노인에 이르기까지 다양함에도 불구하고 제시 향에 단순 알코올이나 단순 초산염이 주로 사용되었으며, 냄새 인지력이나 식별력 둥 지성적인 측면에서의 평가가 대부분이었다. 본 연구에서는 후각기능이 정상인 19～68세 50명을 대상으로 6종의 천연향에 대해 안정/폐안 상태에서 ECG, 피부저항, 그리고 주관평가를 실시하여 서로 다른 연령층에 따른 변화를 살펴보고자 하였다. 그 결과, 20대, 40대의 청\ulcorner중년층은 lemon을, 60대는 Lavender를 긍정적으로 반응\ulcorner평가하였다. 특히 40대 그룹은 평균 RR 간격, 심박수, 피부저항, 주관평가의 결과에서 가장 높은 상관성을 보여 후각기능이 가장 성숙한 연령대임이 확인되었다. 제시 향에 대해 연령별로 상이하게 반응/평가한 본 연구결과는 연령별로 차별화된 향장품 개발뿐만 아니라 인공냄새 그리고 맛의 개발에도 응용이 가능할 것으로 여겨진다.

• 한국식품조리과학회지
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• 제33권3호
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• pp.256-263
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• 2017

Purpose: Essential oils are secondary metabolites of herbs and have antibacterial activities against foodborne pathogens. However, their applications for food protection are limited due to the hydrophobic and volatile natures of essential oils. Methods: In this study, essential oil nanoemulsions of rosemary and lavender were formulated with non-ionic surfactant Tween 80 and water using ultrasonic emulsification, and their antibacterial effects were determined. Results: The antibacterial activities of nanoemulsions were evaluated against 12 strains of 10 bacterial species, and significant antibacterial effects were observed against four Gram-positive and four Gram-negative bacteria but not against Streptococcus mutans and Shigella sonnei. In the disc diffusion test, the diameter of the inhibition zone proportionally increased with the concentration of nanoemulsions. Using cell turbidity measurement, minimum bactericidal concentration (MBC) of the nanoemulsions, which is the lowest concentration reducing viability of the initial bacterial inoculum by ${\geq}99.9%$, was significantly higher than the minimum inhibitory concentration (MIC) of the nanoemulsions. The largest bactericidal effects of lavender and rosemary essential oil nanoemulsions were observed against S. enterica and S. aureus, respectively. Conclusion: Nanoemulsion technique could improve antibacterial activity of essential oil nanoemulsions by increasing the solubility and stability of essential oils. Our findings shed light on the potential use of essential oil nanoemulsions as an alternative to chemical sanitizers in food protection.

• 한국패션뷰티학회지
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• 제2권3호
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• pp.19-26
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• 2004

석창포와 에센셜오일 Geranium(Pelargonum aspeum), lemongrass(Cymbpogen), Cypress(Cupressus Sempervirens), Chamomile Roman(Anthemis nobilis), Tea tree(malaleuca lterniflia), Bergamot(citrus aurant bergamia), lavender(Lavendula officinalis), Sandal wood(Santalum album)을 혼합하여 나타나는 항균 시너지 효과를 Streptococcus aureus, Pseudomonas aeruginosa, Candida albicans에 대하여 검토 해본 결과 다음과 같은 사실이 확인되었다. 1. 석창포는 Streptococcus aureus, Pseudomonas aeruginosa, Candida albicans에 대하여 뚜렷한 항균 효과를 나타냈다. 2. 아로마오일, Geranium(Pelargonum aspeum) lemongrass(Cymbpogen), Cypress(Cupressus Sempervirens), Chamomile Roman(Anthemis nobilis), Tea tree(malaleuca lterniflia), Bergamot(citrus aurant bergamia).lavender(Lavendula officinalis), Sandal wood(Santalum album)등은 Streptococcus aureus, Pseudomonas aeruginosa, Candida albicans에 대하여 강력한 항균 효과를 나타냈다. 3. 석창포와 아로마오일을 혼합 시에도 Streptococcus aureus, Pseudomonas aeruginosa, Candida albicans에 대하여 항균 시너지 효과를 나타냈다. 이로써 석창포와 아로마오일 모두 항균력을 가지고 있음이 확인되었고, 혼합시 또한 석창포와 아로마 오일의 대부분 상승효과가 있으며 이는 화장품에 폭넓게 응용할 수 있으리라 사료된다.

• Journal of Mycology and Infection
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• 제23권4호
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• pp.91-98
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• 2018

Background: Malassezia, a lipophilic yeast, is a causative agent for dandruff and seborrheic dermatitis. Many biological agents have been studied for anti-Malassezia effect but further studies are needed for their clinical application. Objective: The study was conducted to evaluate the inhibitory effect of different natural essential oils and a fruit extract on Malassezia species in an in vitro study and a clinical trial. Methods: The antifungal effects of natural essential oils and a fruit extract on Malassezia species (M. furfur and M. sympodialis) were evaluated by measuring the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) and using the disc diffusion method. Natural essential oils of citron seed, lavender, and rosemary and citrus junos fruit extract were used for the in vitro study. The clinical trial was conducted with a shampoo containing four ingredients. A total of 22 subjects used the shampoo every day for 4 weeks and were evaluated using clinical photography, trichoscopy, and sebumeter at baseline, 2 weeks, and 4 weeks after treatment. Results: Antifungal activity of agents was relatively lower in lavender and rosemary essential oils at MIC and MFC. Disc diffusion method revealed same results. In the clinical trial, the amount of sebum decreased statistically significantly and erythema, dandruff, and lesion extent also improved. Conclusion: The natural essential oils and fruit extract are effective for suppressing Malassezia activity, therefore these might be used as an alternative for treatment of dandruff and seborrheic dermatitis.